BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0132.0032.p (220 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC0400 [IQR] COG1028 Dehydrogenases with different specificities... 207 1e-53 PA2892 [IQR] COG1028 Dehydrogenases with different specificities... 202 5e-52 Rv3224 [IQR] COG1028 Dehydrogenases with different specificities... 202 7e-52 MT3321 [IQR] COG1028 Dehydrogenases with different specificities... 202 7e-52 mll2413 [IQR] COG1028 Dehydrogenases with different specificitie... 199 3e-51 >CC0400 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 285 Score = 207 bits (527), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 102/220 (46%), Positives = 142/220 (64%), Gaps = 2/220 (0%) Query: 2 AEDIRKLGTAALPLRVDVRDADALANAIERTVQEFGGLDILVNNASAISPTGLLDTPARK 61 A++I G ALPL VDVR+ ++ A+++ V +FGG+DI VNNASAIS T L T ++ Sbjct: 53 AKEIEDAGGKALPLVVDVREESSVQEAVDKAVAQFGGIDICVNNASAISLTPTLMTDMKR 112 Query: 62 FDLLSAVNGRATYICAYHAVPHLKRSSNPHVLTLSPPLPKSAIWLGKYPAYATSKYSMTM 121 +DL+ +N R T++ + +PHLK + NPHVL LSPPL S W G + AY +K+ M+M Sbjct: 113 YDLMHQINTRGTFLTSKACIPHLKNAENPHVLMLSPPLDMSPRWFGSHVAYTMAKFGMSM 172 Query: 122 YTLALAEEFRSFGIAANALWPKTMIATDAVR--VHYQSDYRRSRSPSIMADAAHFIVTQG 179 L +AEEF+ GIA NALWP+T IAT A++ + + R R+P IMADAA+ I + Sbjct: 173 CVLGMAEEFKPDGIAFNALWPRTGIATAAIQFALTGEEGLRHCRTPEIMADAAYGIFNKP 232 Query: 180 SREFSGRTLIDEEVLRLQGVDDLSVYAIDPASQLAPDILI 219 SR+FSG LID+ L +GV D Y +DP + L PD + Sbjct: 233 SRDFSGNFLIDDTFLYGEGVRDFDHYKVDPTASLMPDFFV 272 >PA2892 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 274 Score = 202 bits (513), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 102/223 (45%), Positives = 144/223 (64%), Gaps = 3/223 (1%) Query: 1 VAEDIRKLGTAALPLRVDVRDADALANAIERTVQEFGGLDILVNNASAISPTGLLDTPAR 60 VA ++ G ALPL++DVRD A+A A+ R + FGG+D LVNNA AI G+ + Sbjct: 52 VAAEVEAAGGQALPLQLDVRDEQAVAAAMARAAERFGGIDALVNNAGAIRLVGVEKLEPK 111 Query: 61 KFDLLSAVNGRATYICAYHAVPHLKRSSNPHVLTLSPPLPKSAIWLGKYPAYATSKYSMT 120 +FDL+ +N RA +C+ A+P+L+RS+N H+L+LSPP+ + W ++ Y +KY M+ Sbjct: 112 RFDLMYQINTRAVLVCSQAALPYLRRSANGHILSLSPPINLAGRWFAQHGPYTVTKYGMS 171 Query: 121 MYTLALAEEFRSFGIAANALWPKTMIATDAVRVHYQSD--YRRSRSPSIMADAAHFIVTQ 178 M TL + EEF + I+ NALWPKTMIAT A+ S +RR+R+P+IMADAAH I+T Sbjct: 172 MLTLGMHEEFGKYAISVNALWPKTMIATAAIEFELGSRDAFRRARTPAIMADAAHAILTS 231 Query: 179 GSREFSGRTLIDEEVLRLQGVDDLSVYAIDP-ASQLAPDILIE 220 R SGR L+DEE+LR +G D Y DP L PD+ ++ Sbjct: 232 EGRSLSGRLLVDEELLRERGQSDFEQYRYDPEGGALVPDLFLD 274 >Rv3224 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mtu Mycobacterium tuberculosis H37Rv Length = 282 Score = 202 bits (513), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 100/221 (45%), Positives = 146/221 (66%), Gaps = 3/221 (1%) Query: 2 AEDIRKLGTAALPLRVDVRDADALANAIERTVQEFGGLDILVNNASAISPTGLLDTPARK 61 A+++ + G ALP+ D+RD DA+A+A+ TV++FGG+DI VNNASAI+ + + P ++ Sbjct: 53 AKELEEAGGQALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKR 112 Query: 62 FDLLSAVNGRATYICAYHAVPHLKRSSNPHVLTLSPPLPKSAIWLGKYPAYATSKYSMTM 121 FDL++ + R TY + +PH+K NPH+LTLSPP+ WL + AY +KY MT+ Sbjct: 113 FDLMNGIQVRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWL-RPTAYMMAKYGMTL 171 Query: 122 YTLALAEEFRSFGIAANALWPKTMIATDAVRVHYQSD--YRRSRSPSIMADAAHFIVTQG 179 L +AEE R+ GIA+N LWP+TM+AT AV+ D RSR P + ADAA+ IV + Sbjct: 172 CALGIAEEMRADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKP 231 Query: 180 SREFSGRTLIDEEVLRLQGVDDLSVYAIDPASQLAPDILIE 220 + E++G+TL+ E+VL GV DLSVY P + L D+ +E Sbjct: 232 ATEYTGKTLLCEDVLVESGVTDLSVYDCVPGATLGVDLWVE 272 >MT3321 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MtC Mycobacterium tuberculosis CDC1551 Length = 282 Score = 202 bits (513), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 100/221 (45%), Positives = 146/221 (66%), Gaps = 3/221 (1%) Query: 2 AEDIRKLGTAALPLRVDVRDADALANAIERTVQEFGGLDILVNNASAISPTGLLDTPARK 61 A+++ + G ALP+ D+RD DA+A+A+ TV++FGG+DI VNNASAI+ + + P ++ Sbjct: 53 AKELEEAGGQALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKR 112 Query: 62 FDLLSAVNGRATYICAYHAVPHLKRSSNPHVLTLSPPLPKSAIWLGKYPAYATSKYSMTM 121 FDL++ + R TY + +PH+K NPH+LTLSPP+ WL + AY +KY MT+ Sbjct: 113 FDLMNGIQVRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWL-RPTAYMMAKYGMTL 171 Query: 122 YTLALAEEFRSFGIAANALWPKTMIATDAVRVHYQSD--YRRSRSPSIMADAAHFIVTQG 179 L +AEE R+ GIA+N LWP+TM+AT AV+ D RSR P + ADAA+ IV + Sbjct: 172 CALGIAEEMRADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKP 231 Query: 180 SREFSGRTLIDEEVLRLQGVDDLSVYAIDPASQLAPDILIE 220 + E++G+TL+ E+VL GV DLSVY P + L D+ +E Sbjct: 232 ATEYTGKTLLCEDVLVESGVTDLSVYDCVPGATLGVDLWVE 272 >mll2413 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 288 Score = 199 bits (507), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 101/220 (45%), Positives = 138/220 (62%), Gaps = 2/220 (0%) Query: 2 AEDIRKLGTAALPLRVDVRDADALANAIERTVQEFGGLDILVNNASAISPTGLLDTPARK 61 A++I + G ALP+ D+R+ +A A+ +TV++FGG+DI VNNASAI TG L T ++ Sbjct: 53 AQEIEQAGGKALPVLCDIREEAQVAEAVAKTVEKFGGIDICVNNASAIQLTGTLQTDMKR 112 Query: 62 FDLLSAVNGRATYICAYHAVPHLKRSSNPHVLTLSPPLPKSAIWLGKYPAYATSKYSMTM 121 +DL+ +N R T++ + +PHLK + NPH+L L+PPL A W + AY +K+ M+M Sbjct: 113 YDLMHQINTRGTFLVSKMCIPHLKLADNPHILNLAPPLDMKAKWFKNHVAYTMAKFGMSM 172 Query: 122 YTLALAEEFRSFGIAANALWPKTMIATDAVR--VHYQSDYRRSRSPSIMADAAHFIVTQG 179 TL ++ EF GIA N+LWP + I T AVR + + SRSP IMADAAH I + Sbjct: 173 CTLGMSAEFAKDGIAVNSLWPISTIDTAAVRNLLGGATVAAMSRSPDIMADAAHAIFMRP 232 Query: 180 SREFSGRTLIDEEVLRLQGVDDLSVYAIDPASQLAPDILI 219 SRE SG IDEEVLR +GV D S YA LA D + Sbjct: 233 SREASGNFYIDEEVLRAEGVTDFSAYAPGATGPLAGDFFV 272