BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0132.0023.p (398 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1016 [I] COG0183 Acetyl-CoA acetyltransferase Pae Pseudomonas ... 256 8e-68 MTH793 [I] COG0183 Acetyl-CoA acetyltransferase Mth Methanotherm... 183 5e-46 MA4042 [I] COG0183 Acetyl-CoA acetyltransferase Mac Methanosarci... 182 1e-45 AF2416 [I] COG0183 Acetyl-CoA acetyltransferase Afu Archaeoglobu... 174 2e-43 AF0438 [I] COG0183 Acetyl-CoA acetyltransferase Afu Archaeoglobu... 172 2e-42 >PA1016 [I] COG0183 Acetyl-CoA acetyltransferase Pae Pseudomonas aeruginosa Length = 383 Score = 256 bits (653), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 156/399 (39%), Positives = 224/399 (56%), Gaps = 24/399 (6%) Query: 5 SLRGKVAVIGIGLSAVGKVPGRSPLSLAAEAAANALADAGLAKSQVDGVL---SSHAFAS 61 ++RGK A++GIG + VG+ PG S + L +A+ A+ADAGL S +D + SSHAF + Sbjct: 4 AIRGKTAIVGIGSAGVGEAPGYSAIELLGQASLKAIADAGLKLSDIDAIFAATSSHAFPT 63 Query: 62 PFHRFSVAFSEYFGIRPTFSNTLQVSGATAATMFSIGAAAIHGGPAPVKKKKVVLLVAAD 121 ++ +EY GIRP F + + G++ A+ G ++ ++ Sbjct: 64 ------LSVAEYLGIRPKFVDGTNIGGSSFELHLLQATLALEAGLC----DAALICYGSN 113 Query: 122 SLMTGLTPDLALRSLTESRDQQYEMPFGI--PVANTFAMTAHRHMREFGTTPEQLAEVAV 179 G R ++ S Q +E P+ P+ +A+ A RHM ++GTT EQLAEVAV Sbjct: 114 QRTAGG------RLVSMSEPQWHETPYKPRHPI-TAYALAASRHMHQYGTTREQLAEVAV 166 Query: 180 VHRRHAARTPGAQQTTPITAADVLSSPMVTTPYHKLDCSLISDGGAAFVLTSAEHAKALG 239 R+ A P A P++ DVL++ MV+ P DC L++DGG A V+ AE A+ L Sbjct: 167 SARQWANLNPEAFARGPLSVDDVLAARMVSDPLSAADCCLVTDGGGACVVVRAERARDL- 225 Query: 240 IGRSIYILGCGECYTHEHIFLMPSLTTTGAVESSRRAYAMAGYQPRDMDVAGIYDCFTGT 299 +Y LG H I MP LT T A ES+ RA MAG + D+D+ +YD FT Sbjct: 226 PNAPVYFLGAAGAQWHRSIVSMPDLTVTAASESAPRAMQMAGVRHADIDLVMLYDAFTIN 285 Query: 300 VVMMLEDLGFCRKGEGGPFVADGQMSYGGQIPSNTHGGLLSFAHSGMPGALFHFHEVIAQ 359 ++ LEDLGFC KGEGGPFV G+++ GG++ NT+GG LS H GM G +F E + Q Sbjct: 286 TLLFLEDLGFCAKGEGGPFVQGGRIAPGGELAVNTNGGGLSCVHPGMYG-MFLIIEAVTQ 344 Query: 360 LRGQCGERQVDRAALGLVHSLGAGFATNATAILGTEETL 398 LR Q GERQ+ +A + L+H G ++ TA+LGT +TL Sbjct: 345 LRRQAGERQLAKADVALLHGNGGTLSSQVTALLGTGDTL 383 >MTH793 [I] COG0183 Acetyl-CoA acetyltransferase Mth Methanothermobacter thermautotrophicus Length = 383 Score = 183 bits (465), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 123/389 (31%), Positives = 194/389 (49%), Gaps = 15/389 (3%) Query: 9 KVAVIGIGLSAVGKVPGRSPLSLAAEAAANALADAGLAKSQVD----GVLSSHAFASPFH 64 VAVIG+ + G++ S + EA A+ DAG+ + +D G +S+ F H Sbjct: 3 DVAVIGVSQTKFGELWDVSFRDMITEAGLGAIEDAGVEGADLDAMYVGNMSAGLFIKQEH 62 Query: 65 RFSVAFSEYFGIRPTFSNTLQVSGATAATMFSIGAAAIHGGPAPVKKKKVVLLVAADSLM 124 S +++ G+ P S ++ + A+ G A+ G +V+ + + Sbjct: 63 -ISSLIADHAGLTPIPSTRVEAACASGGLALRSGIMAVASG-----YHDIVIAAGVEKMT 116 Query: 125 TGLTPDLALRSLTESRDQQYEMPFGIPVANTFAMTAHRHMREFGTTPEQLAEVAVVHRRH 184 + P A+ + + DQ++E G+ + +AM A RHM E+GTT EQLA V+V++ + Sbjct: 117 DVVDPTPAIAT---ASDQEWEAQQGVTFPSLYAMMARRHMYEYGTTREQLAMVSVINHEN 173 Query: 185 AARTPGAQQTTPITAADVLSSPMVTTPYHKLDCSLISDGGAAFVLTSAEHAKALGIGRSI 244 A+ P AQ +T V++S MV P LDCS ISDG AA +L A+ A+ + Sbjct: 174 ASNNPRAQFPMKVTVEQVMNSTMVADPLRLLDCSPISDGAAAVILCPADMAREY-TDTPV 232 Query: 245 YILGCGECYTHEHIFLMPSLTTTGA-VESSRRAYAMAGYQPRDMDVAGIYDCFTGTVVMM 303 Y+ + + +T A V ++R A+ MA P D+D+ ++DCF+ ++ Sbjct: 233 YVKASAQASGTIALHDRRDITRIDATVNAARNAFKMAKLTPGDIDLVEVHDCFSINGILA 292 Query: 304 LEDLGFCRKGEGGPFVADGQMSYGGQIPSNTHGGLLSFAHSGMPGALFHFHEVIAQLRGQ 363 +EDLGF KGEGG DG G IP N GGL + H + EV+ QLRG+ Sbjct: 293 VEDLGFVEKGEGGRAFEDGMTRIDGDIPVNPSGGLKARGHPLGATGIAQAAEVVWQLRGE 352 Query: 364 CGERQVDRAALGLVHSLGAGFATNATAIL 392 G+RQV+ A +G+ H++G T A I Sbjct: 353 AGKRQVEGAEIGMTHNIGGTGGTAAVHIF 381 >MA4042 [I] COG0183 Acetyl-CoA acetyltransferase Mac Methanosarcina acetivorans str.C2A Length = 390 Score = 182 bits (462), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 129/392 (32%), Positives = 194/392 (49%), Gaps = 12/392 (3%) Query: 10 VAVIGIGLSAVGKVPGRSPLSLAAEAAANALADAGLAKSQVD----GVLSSHAFASPFHR 65 VA+IG+ + G++ RS + EAA L DA ++ ++D G +S F H Sbjct: 4 VAIIGVKNTKFGELWDRSLRDIIVEAAIGVLDDADVSGKEIDALYLGNMSGGRFVDQEH- 62 Query: 66 FSVAFSEYFGIRPTFSNTLQVSGATAATMFSIGAAAIHGGPAPVKKKKVVLLVAADS-LM 124 ++Y G+ S L + + G A+ V ++VAA + M Sbjct: 63 IGALIADYSGL----SKNLHIPATRVEAACASGGLALRQAIMAVASGYSNIVVAAGAEKM 118 Query: 125 TGLTPDLALRSLTESRDQQYEMPFGIPVANTFAMTAHRHMREFGTTPEQLAEVAVVHRRH 184 T + + A +L + D+++E G +AM A HM +GTT EQLAEVAV + ++ Sbjct: 119 TDVGTEEASSALAAAADREWEGMAGATFPGLYAMIAKLHMHRYGTTSEQLAEVAVKNHKN 178 Query: 185 AARTPGAQQTTPITAADVLSSPMVTTPYHKLDCSLISDGGAAFVLTSAEHAKALGIGRSI 244 + P AQ I+ DVL S MV P H DCS I+DG +A V+ A+ A I Sbjct: 179 GSLNPIAQYKNEISVDDVLKSIMVADPLHIFDCSPITDGASALVVAPADIAHKY-TDTPI 237 Query: 245 YILGCGECYTHEHIFLMPSLTTTGA-VESSRRAYAMAGYQPRDMDVAGIYDCFTGTVVMM 303 YI + + +TT + V +++RAY+MA P D+D+ ++DCFT + Sbjct: 238 YIKATAQASDTIALHDRRDITTLDSTVMAAKRAYSMAKLTPEDIDLVEVHDCFTIAEICA 297 Query: 304 LEDLGFCRKGEGGPFVADGQMSYGGQIPSNTHGGLLSFAHSGMPGALFHFHEVIAQLRGQ 363 +EDLGF KG+GG +G+ + GG+IP NT GGL + H + E++ QLRG Sbjct: 298 IEDLGFAEKGKGGIVTENGETAIGGRIPVNTSGGLKACGHPVGATGIKQAVEIVTQLRGD 357 Query: 364 CGERQVDRAALGLVHSLGAGFATNATAILGTE 395 G+RQV A G+ H++G AT IL E Sbjct: 358 AGKRQVAGAEYGMTHNVGGSGATAVIHILSRE 389 >AF2416 [I] COG0183 Acetyl-CoA acetyltransferase Afu Archaeoglobus fulgidus Length = 384 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 128/397 (32%), Positives = 196/397 (49%), Gaps = 30/397 (7%) Query: 9 KVAVIGIGLSAVGKVPGRSPLSLAAEAAANALADAGLAKSQVD----GVLSSHAFASPFH 64 +VAV+G+G S G++ + + EA AL DA L +++ G +S + H Sbjct: 3 RVAVVGVGQSKFGELWEKGFRDIVLEAGREALEDADLEGREIEAMFVGNMSGGRYLGQEH 62 Query: 65 RFSVAFSEY-----FGIRPTFSNTLQVSGATAATMFSIGAAA-IHGGPAPVKKKKVVLLV 118 + ++Y FGI T SG A + A+ +H +V+ Sbjct: 63 -VAALIADYAGLAEFGIPATRVEAADASGGLAVRQAYMAVASGLH---------DIVIAA 112 Query: 119 AADSLMTGLTPDLALRSLTESRDQQYEMPFGIPVANTFAMTAHRHMREFGTTPEQLAEVA 178 A+ + P ++ L+ S D ++E G + +A+ A HM FGTT E LA V+ Sbjct: 113 GAEKVTDVDDP---MQILSSSVDVEWENFVGGSLPALYAIIARLHMDSFGTTEEDLALVS 169 Query: 179 VVHRRHAARTPGAQQTTPITAADVLSSPMVTTPYHKLDCSLISDGGAAFVLTSAEHAKAL 238 V + R+ A+ P AQ I DVL+SP V P LDC+ +SDG AA +L S + A+ + Sbjct: 170 VKNHRNGAKNPKAQFRKEIRVEDVLNSPYVAEPLKLLDCASVSDGAAAVILASEDVAREI 229 Query: 239 GIGRSIYILGCGECYTHEHIFLMPS---LTTTGAVESSRRAYAMAGYQPRDMDVAGIYDC 295 ++I C + +++ L L+ V++SR AY +AG P+D+ VA ++D Sbjct: 230 -TDTPVFIEACTQA--SDYLALQSRKDILSMRAVVKASRDAYELAGVGPKDIQVAEVHDS 286 Query: 296 FTGTVVMMLEDLGFCRKGEGGPFVADGQMSYGGQIPSNTHGGLLSFAHSGMPGALFHFHE 355 FT ++ EDLGF KG+G V +G GG+IP N GGL + H+ + E Sbjct: 287 FTIAEILAYEDLGFAEKGKGAELVREGVTEIGGKIPVNPSGGLKACGHAVGATGVRQIVE 346 Query: 356 VIAQLRGQCGERQVDRAALGLVHSLGAGFATNATAIL 392 + QLRG+ GERQVD A GL ++G AT +IL Sbjct: 347 LTLQLRGEAGERQVD-AETGLALNIGGTGATAVVSIL 382 >AF0438 [I] COG0183 Acetyl-CoA acetyltransferase Afu Archaeoglobus fulgidus Length = 387 Score = 172 bits (435), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 129/382 (33%), Positives = 183/382 (47%), Gaps = 18/382 (4%) Query: 9 KVAVIGIGLSAVGKVPGRSPLSLAAEAAANALADAGLAKSQVDGVLSSHAFASPFHRF-S 67 +V VIG+G S G+ LA EA AL DAG+ + +V+ + + + Sbjct: 2 RVGVIGVGCSRFGRRDDAVIQELAYEAVKEALDDAGITQDEVELSVVGSVNTRGYELMPA 61 Query: 68 VAFSEYFGIRPTFSNTLQVSGATAATMFSIGAAAIHGGPAPVK----KKKVVLLVAADSL 123 V +EY G ++ + AT A +I G A V +K+ + A SL Sbjct: 62 VPVNEYCGFAGKGPLRVEAACATGAAAVYTAYTSIASGMADVAIAIGVEKMTEVDTATSL 121 Query: 124 MTGLTPDLALRSLTESRDQQYEMPFGIPVANTFAMTAHRHMREFGTTPEQLAEVAVVHRR 183 G L + +G +AM A HM ++GTT EQ+A+VAV R Sbjct: 122 AIGGRAGNYLWEFHQ---------YGTTFPAYYAMHATAHMAKYGTTEEQMAKVAVKAHR 172 Query: 184 HAARTPGAQQTTPITAADVLSSPMVTTPYHKLDCSLISDGGAAFVLTSAEHAKALGIGRS 243 +AAR P A I DVL+S +T P DCS ISDG AA +L S E + LGI Sbjct: 173 NAARNPKAHFQKEIAVEDVLNSRYITYPLKLYDCSPISDGSAAAILASEEKIRELGIDDV 232 Query: 244 IYILGCGECYTHEHIFLMPSLTTTGAVESSRR-AYAMAGYQP--RDMDVAGIYDCFTGTV 300 ++I G ++ S A +R AY AG + + +D A ++DCFT Sbjct: 233 VWIDSVGYASDTSNMTNRESFVGLKATVLAREMAYRKAGIEEPVKQLDFATVHDCFTIAE 292 Query: 301 VMMLEDLGFCRKGEGGPFVADGQMSYGGQIPSNTHGGLLSFAHSGMPGALFHFHEVIAQL 360 +M EDLGFCRKGEGG V G+ GG++P NT GGL + H + +E++ QL Sbjct: 293 IMAYEDLGFCRKGEGGKLVESGETELGGKLPVNTFGGLKAKGHPLAATGVAMVYEIVKQL 352 Query: 361 RGQCGERQVD-RAALGLVHSLG 381 RG+ GE QV+ R L+H++G Sbjct: 353 RGEAGELQVELRNNRALLHNVG 374