BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0132.0003.p (305 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3594 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 190 3e-48 PA2510 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 189 7e-48 BS_alsR [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 186 6e-47 STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 176 4e-44 PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 176 7e-44 >PA3594 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 295 Score = 190 bits (483), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 106/256 (41%), Positives = 155/256 (60%) Query: 8 MDLRRLVYFVAVAEELHFGRAASRLAIAQPPLSRQIAQLESDLGVMLIDRSRSQIRLTQA 67 MDLR+L YF+AVAEELHFGRAA+RL I+QP LS I +LE LG L+ R+ ++LT A Sbjct: 1 MDLRQLRYFIAVAEELHFGRAAARLFISQPALSFDIKKLEEQLGTQLLLRNNKSVKLTGA 60 Query: 68 GSVLLERARDVLERLDRTHREIKRIGEGFSGHLRVAFVGSATYGVLPSVIQAFRSAYPDV 127 G VLL AR++L + ++ R + EG G LRV FV S Y LP + F +P++ Sbjct: 61 GQVLLVEARNLLLQAEKVKRLTQLSAEGDVGQLRVGFVNSMLYRGLPRAMSRFEREHPNM 120 Query: 128 ELALSAMNNAEQKRAVIQREIDIAIARPSLDDEELKSEPLLHEPLILALSDTSSLLEQQV 187 E+ L MN+AEQ +A+ + +ID+ E+ SEPL+ +P + L L Q Sbjct: 121 EVVLGEMNSAEQAQALQRGQIDLGFVHWGRLPAEIVSEPLISDPFLCCLPAGHRLAGQAR 180 Query: 188 PRLAALKAETFILYPRKPRPSFADHILNICLEEGFIPKSQVLAQDYQTAISLVSVGVGIA 247 LA L+ E FIL+PR P + D I+ C++ GF P+ + A+ +QT ++V +G+G+A Sbjct: 181 LDLAELRDEDFILFPRHVSPHYHDLIIARCVDAGFSPRIRHEARLWQTVAAMVGLGMGVA 240 Query: 248 LVPKSVSEAERPGVAY 263 L+P+++ A R V Y Sbjct: 241 LIPETLCLAWRNEVRY 256 >PA2510 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 290 Score = 189 bits (480), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 117/281 (41%), Positives = 162/281 (57%), Gaps = 3/281 (1%) Query: 8 MDLRRLVYFVAVAEELHFGRAASRLAIAQPPLSRQIAQLESDLGVMLIDRSRSQIRLTQA 67 M+LR L YF A+A L+F RAA +L IAQPPLSRQI QLE LGV L++R R +RLT+A Sbjct: 1 MELRHLRYFQALARTLNFTRAAEQLHIAQPPLSRQIQQLEEMLGVALLERGRP-LRLTEA 59 Query: 68 GSVLLERARDVLERLDRTHREIKRIGEGFSGHLRVAFVGSATYGVLPSVIQAFRSAYPDV 127 G E++ +L++L+ +RIG+G + FV SA YGVLP +I+ R P++ Sbjct: 60 GRFFHEQSATLLDQLESICDSTRRIGQGQRQWFGIGFVPSALYGVLPELIRHLRGD-PEL 118 Query: 128 ELALSAMNNAEQKRAVIQREIDIAIARPSLDDEELKSEPLLHEPLILALSDTSSLLEQQV 187 EL L M +Q A+ IDI R +DD ++ L EPL+ AL LL Q + Sbjct: 119 ELGLLEMTTLQQVEALKSGRIDIGFGRIRIDDPAIRQSVLSEEPLVAALPAGHPLLGQPL 178 Query: 188 PRLAALKAETFILYPRKPRPSFADHILNICLEEGFIPKSQVLAQDYQTAISLVSVGVGIA 247 L L E F+LYP +PRPS+ADH+L + G + A + QTAI LV+ G+G Sbjct: 179 -SLERLSREPFVLYPGQPRPSYADHVLALFATHGLSLRVTQWANEMQTAIGLVAAGLGAT 237 Query: 248 LVPKSVSEAERPGVAYRAYEGHNPGTALSLNYRRDNRMPHL 288 LVP SV R VAY+A + + + ++ R+ + PHL Sbjct: 238 LVPASVQLQHRDDVAYQALADASLTSPIIVSRRQGDGSPHL 278 >BS_alsR [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 302 Score = 186 bits (472), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 101/297 (34%), Positives = 157/297 (52%) Query: 8 MDLRRLVYFVAVAEELHFGRAASRLAIAQPPLSRQIAQLESDLGVMLIDRSRSQIRLTQA 67 M+LR L YF+AVAEELHFG+AA RL + QPPLS+QI QLE ++GV L+ R++ + LT A Sbjct: 1 MELRHLQYFIAVAEELHFGKAARRLNMTQPPLSQQIKQLEEEVGVTLLKRTKRFVELTAA 60 Query: 68 GSVLLERARDVLERLDRTHREIKRIGEGFSGHLRVAFVGSATYGVLPSVIQAFRSAYPDV 127 G + L R L ++ + +R G G L + FVGSATY LP +++ +R +P V Sbjct: 61 GEIFLNHCRMALMQIGQGIELAQRTARGEQGLLVIGFVGSATYEFLPPIVREYRKKFPSV 120 Query: 128 ELALSAMNNAEQKRAVIQREIDIAIARPSLDDEELKSEPLLHEPLILALSDTSSLLEQQV 187 ++ L ++++ Q+ +++ IDI I P L L E P +LAL L ++ Sbjct: 121 KIELREISSSRQQEELLKGNIDIGILHPPLQHTALHIETAQSSPCVLALPKQHPLTSKES 180 Query: 188 PRLAALKAETFILYPRKPRPSFADHILNICLEEGFIPKSQVLAQDYQTAISLVSVGVGIA 247 + L+ E I ++ P+ + C + GF P A +YQ I LVS G+G+ Sbjct: 181 ITIEDLRDEPIITVAKEAWPTLYMDFIQFCEQAGFRPNIVQEATEYQMVIGLVSAGIGMT 240 Query: 248 LVPKSVSEAERPGVAYRAYEGHNPGTALSLNYRRDNRMPHLFNFLKVAQDVTRRQRK 304 VP S + V YR + + YR+DN P + +F+ ++ R ++ Sbjct: 241 FVPSSAKKLFNLDVTYRKMDQIQLNAEWVIAYRKDNHNPLIKHFIHISNCQQTRTKE 297 >STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 292 Score = 176 bits (447), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 105/287 (36%), Positives = 153/287 (53%), Gaps = 2/287 (0%) Query: 8 MDLRRLVYFVAVAEELHFGRAASRLAIAQPPLSRQIAQLESDLGVMLIDRSRSQIRLTQA 67 M+LR + YF+AVAEE HF RAA++L I QPPLS+QI LE +LG L R LT+A Sbjct: 1 MELRHIRYFLAVAEERHFTRAATKLGIGQPPLSQQIKDLERELGAQLFRRVPHGAELTEA 60 Query: 68 GSVLLERARDVLERLDRTHREIKRIGEGFSGHLRVAFVGSATYG-VLPSVIQAFRSAYPD 126 G + + + R +R+ G SG LRV F SA + V+P I+ F+ AYPD Sbjct: 61 GKAFYDVVKGMPATATRAVLAAQRVARGESGVLRVGFTASAAFNSVVPGAIRTFKRAYPD 120 Query: 127 VELALSAMNNAEQKRAVIQREIDIAIARPSL-DDEELKSEPLLHEPLILALSDTSSLLEQ 185 V L L N + + + +D+A RP +E + L EP+++ L++T Sbjct: 121 VRLQLEEGNTTQLADELNEGSLDVAFLRPGFTGNERFQLRLLSEEPMVIVLAETHPAAAC 180 Query: 186 QVPRLAALKAETFILYPRKPRPSFADHILNICLEEGFIPKSQVLAQDYQTAISLVSVGVG 245 + L+ LK E F+L+PR+ S D ++ C + GF PK L + I+LVS +G Sbjct: 181 KQIALSILKDEFFLLFPREIGLSLYDAVIKACGKAGFEPKIGQLVPQISSVINLVSAEMG 240 Query: 246 IALVPKSVSEAERPGVAYRAYEGHNPGTALSLNYRRDNRMPHLFNFL 292 +++VP S+ + GV YR P L+L YRR + P L NF+ Sbjct: 241 VSMVPDSMRQVNVKGVVYRPVADQMPVAKLALAYRRGDTSPTLRNFI 287 >PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 301 Score = 176 bits (445), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 106/296 (35%), Positives = 161/296 (54%), Gaps = 6/296 (2%) Query: 8 MDLRRLVYFVAVAEELHFGRAASRLAIAQPPLSRQIAQLESDLGVMLIDRSRSQIRLTQA 67 M+LR L YF+AVAEELHFGRAA RL I+QPPLS+QI LE ++G L +R+ ++ LT A Sbjct: 1 MELRHLRYFIAVAEELHFGRAAERLGISQPPLSQQIQALEEEIGARLFERTNRRVELTDA 60 Query: 68 GSVLLERARDVLERLDRTHREIKRIGEGFSGHLRVAFVGSATY-GVLPSVIQAFRSAYPD 126 G + L+ +R VL ++D+ +R G G L++ F SA + +PS I AFR AYPD Sbjct: 61 GRLFLDESRQVLAQVDKAVLLARRAHLGELGELKIGFTSSAPFTSTIPSSIHAFRKAYPD 120 Query: 127 VELALSAMNNAEQKRAVIQREIDIAIARPSLDDEELKSEPLLHEPLILALSDTSSLL--E 184 V L L M++ + +A+++ + + + RP + + L EPL+ L L Sbjct: 121 VHLDLQEMSSRQVLKALLEESLQVGVIRPLALPDAVHWVELFREPLVAVLRADHPLAAGS 180 Query: 185 QQVPRLAALKAETFILYPRKPRPSFADHILNICLEEGFIPKSQVLAQDYQTAISLVSVGV 244 + +AAL E F+ +PR D ++ + + GF P+ A + T I LVS G+ Sbjct: 181 EDGLAIAALAEEPFVFFPRSYGTGLYDQVIALTRQAGFSPRIAQEASEAMTIIGLVSAGL 240 Query: 245 GIALVPKSVSEAERPGVAYRAYEGHNPGTALSLNYRRDNRMPHLFNFLKVAQDVTR 300 G++++P S GV YR TA+ L R++ P +F+ + VTR Sbjct: 241 GVSILPASFRRTRVDGVVYRTLSDPEATTAVWLVRRQNEGSPLALSFIDL---VTR 293