BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0130.0007.p (410 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 289 1e-77 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 276 7e-74 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 265 2e-70 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 263 6e-70 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 252 9e-67 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 289 bits (739), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 169/395 (42%), Positives = 229/395 (57%), Gaps = 31/395 (7%) Query: 7 SRLYGRIAWRLIPFLLACYTVAIIDRFNIGFAKLQFLHDLQIDDAVFGLAAGIFSVGYVA 66 + +Y + R++PFL CY A +DR NIGFAKLQ +DL + DA +GL AGIF GY+ Sbjct: 17 TSVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYML 76 Query: 67 LEVPSNLLLVKVGVRKTLLRIMVLWGVVTMLLALVQNQYHLYLLRFLLGAAEGGFFPGIL 126 EVPSNLLLVK+G R+TL RI++LWG+V+ + V + + Y LRFLLG E GF PG++ Sbjct: 77 FEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAPGMI 136 Query: 127 YYLTLWFPDRVRGRMTSLFVMAVPLGGVIAGPLSGLIMDHMQGVHGLHGWQWLFILEGGP 186 YYLT W+P R ++ + A PLGGVI GP S IM H G GL GWQW+F+ EG P Sbjct: 137 YYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGIP 196 Query: 187 AVLLGIAAYFYLADGPQVASWLSADERRQVA----------AARLSALLHLLRVLLLAQH 236 ++LLGIAAY YL D P A WL+ ++ +A A+ L ++ +LA Sbjct: 197 SILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARAAPGQASSFGKALTEPKLYVLAAA 256 Query: 237 H--------------PAVDADAAETRRRXTEIGWLSGAISVASAIGMXAIGYSSDRTRER 282 + P++ A + +IG S ++A + M A+G SDR ER Sbjct: 257 YFCLICGVYAVGFWLPSILKSAGLS--DLFQIGLYSAIPNLAMIVAMYALGRRSDRRGER 314 Query: 283 RWHVVCCGLVAAA--CFIALQAAQDSVLLTVTLLAVASIGIFAILSLFWTIPNAMLEGSA 340 H ++ A + A + + L+++TL AS IFA S+FW IP L+G+A Sbjct: 315 HLHSAITAVLGAGLLAWAAYATSFPAALISITL---ASAAIFASYSVFWAIPQQHLKGTA 371 Query: 341 AAGGIALISAIGSFGGAVCPALIGWMNVATGSIYA 375 AAGGIALI++IG FGG P LIGW ATGS+ A Sbjct: 372 AAGGIALINSIGLFGGFFSPTLIGWTKEATGSLQA 406 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 276 bits (706), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 162/420 (38%), Positives = 239/420 (56%), Gaps = 28/420 (6%) Query: 2 QDAAHSRLYGRIAWRLIPFLLACYTVAIIDRFNIGFAKLQFLHDLQIDDAVFGLAAGIFS 61 Q + Y + W L+P L+ CY + +DR N+GFAKLQ DLQ D V+GL AG+F Sbjct: 14 QLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFF 73 Query: 62 VGYVALEVPSNLLLVKVGVRKTLLRIMVLWGVVTMLLALVQNQYHLYLLRFLLGAAEGGF 121 +GY LE+PSNL+L +VG R + RIM+ WG+++ +A V Y++RFLLG AE GF Sbjct: 74 IGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGF 133 Query: 122 FPGILYYLTLWFPDRVRGRMTSLFVMAVPLGGVIAGPLSGLIMDHMQGVHGLHGWQWLFI 181 FPGI+ Y++ WFP RGR+ LFV++VPL G+I PLSG IM + G G GWQW+FI Sbjct: 134 FPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFI 193 Query: 182 LEGGPAVLLGIAAYFYLADGPQVASWLSADERR-----------QVAAARLSA------- 223 LEG P+VL+GI + L D A+WL+ E+ A +RL Sbjct: 194 LEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYAHSRLRDAFLQPRV 253 Query: 224 -LLHLLRVLLLAQHH------PAVDADAAETRRRXTEIGWLSGAISVASAIGMXAIGYSS 276 LL L+ L++ + P + D+ + IG+L+ S A+A+ M + S+ Sbjct: 254 WLLTLIYFCLISGFYTIGFWLPTLIRDSGV--KDILSIGFLTAIPSAAAAVTMIVVSRSA 311 Query: 277 DRTRERRWHVVCCGLVAAACFIALQAAQDSVLLTVTLLAVASIGIFAILSLFWTIPNAML 336 DR RERRWH+ ++ A I D++++ + L + ++G + + LFW++P A L Sbjct: 312 DRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFL 371 Query: 337 EGSAAAGGIALISAIGSFGGAVCPALIGWMNVATGSIYAPLALVGTVLGIGMLTLIVCVP 396 GSAAA GIA I++ G+ GG V P ++G++ T S + ++ T L IG L+ +P Sbjct: 372 GGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLFIGA-ALVFLIP 430 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 265 bits (676), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 159/415 (38%), Positives = 235/415 (56%), Gaps = 23/415 (5%) Query: 10 YGRIAWRLIPFLLACYTVAIIDRFNIGFAKLQFLHDLQIDDAVFGLAAGIFSVGYVALEV 69 Y +++WRLIPFLL CY VA +DR N+GFAKLQ L+DL+ + V+GL AGIF +GY EV Sbjct: 28 YRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYFLFEV 87 Query: 70 PSNLLLVKVGVRKTLLRIMVLWGVVTMLLALVQNQYHLYLLRFLLGAAEGGFFPGILYYL 129 PSN++L +VG R + RIM+ WG+++ + V Y++RFLLG AE GFFPGI+ YL Sbjct: 88 PSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYL 147 Query: 130 TLWFPDRVRGRMTSLFVMAVPLGGVIAGPLSGLIMDHMQGVHGLHGWQWLFILEGGPAVL 189 T W+P RGR T+ F+ AV L GVI GP+SG + GV+GL GWQW+F++EG P+V+ Sbjct: 148 TYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVV 207 Query: 190 LGIAAYFYLADGPQVASWLSADER----RQVAA-------ARLSALLHLLRVLLLAQHHP 238 +G+ YL + A WL+ +E+ R +AA A ++A++ RV L++ + Sbjct: 208 IGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQKEDAPIAAIMASPRVWLMSLIYF 267 Query: 239 AVDADAAETRRRXTEIGWLSGAISVASAIGMXAIGY------------SSDRTRERRWHV 286 + + +G S + AI Y S+DRTRERRWH+ Sbjct: 268 SFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRERRWHI 327 Query: 287 VCCGLVAAACFIALQAAQDSVLLTVTLLAVASIGIFAILSLFWTIPNAMLEGSAAAGGIA 346 L A + + L + L + ++GI L LFW++P A L G+ AA GIA Sbjct: 328 AIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIA 387 Query: 347 LISAIGSFGGAVCPALIGWMNVATGSIYAPLALVGTVLGIGMLTLIVCVPRTRHE 401 LI+++G+ G + P +GW+ T S + + L+ + +G L + RT + Sbjct: 388 LINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGALLTLSVPARTVNR 442 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 263 bits (672), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 154/423 (36%), Positives = 242/423 (57%), Gaps = 30/423 (7%) Query: 3 DAAHSRLYGRIAWRLIPFLLACYTVAIIDRFNIGFAKLQFLHDLQIDDAVFGLAAGIFSV 62 + + Y ++A+R+IP L+ CY +A +DR N+GFAKLQ +L +A++GL AG+F + Sbjct: 30 EVVENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFI 89 Query: 63 GYVALEVPSNLLLVKVGVRKTLLRIMVLWGVVTMLLALVQNQYHLYLLRFLLGAAEGGFF 122 GY E+PSN+LL K+G R + RIM+ WG+++ L A VQ ++ Y+LRFLLGAAE GF+ Sbjct: 90 GYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFY 149 Query: 123 PGILYYLTLWFPDRVRGRMTSLFVMAVPLGGVIAGPLSGLIMDHMQGVHGLHGWQWLFIL 182 PG++ YLT WFP RG M +LF P G+ PLSG IMD G GWQW+F+L Sbjct: 150 PGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVL 209 Query: 183 EGGPAVLLGIAAYFYLADGPQVASWLSADER----RQVAA-----ARLSALLHLLR---- 229 E PAV+LG+ YL + + A WL+ +E+ R + A A +L+ L++ Sbjct: 210 EAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASHSLMSLVKNPML 269 Query: 230 --------VLLLAQH-----HPAVDADAAETRRRXTEIGWLSGAISVASAIGMXAIGYSS 276 ++ QH P + + T IG L + + I M S+ Sbjct: 270 WVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSN--VTIGLLGAIPFICAIIAMVIFSRSA 327 Query: 277 DRTRERRWHVVCCGLVAAACFIALQAAQDSVLLTVTLLAVASIGIFAILSLFWTIPNAML 336 D RERRWH+V L+ A F+ +A ++ + ++ L++A+ G+ A LFW++P A+L Sbjct: 328 DHYRERRWHLVVPALLGAVGFVVAASATNTTV-SIIFLSMAAAGVLACAPLFWSLPTAIL 386 Query: 337 EGSAAAGGIALISAIGSFGGAVCPALIGWMNVATGSIYAPLALVGTVLGIGMLTLIVCVP 396 G+AAA GIALI+++ + G + P ++G + AT S + ++ L +G +++C+P Sbjct: 387 SGAAAAAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLILGA-AIVLCIP 445 Query: 397 RTR 399 ++ Sbjct: 446 ASK 448 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 252 bits (644), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 164/397 (41%), Positives = 217/397 (54%), Gaps = 35/397 (8%) Query: 1 MQDAAHSRLYGRIAWRLIPFLLACYTVAIIDRFNIGFAKLQFLHDLQIDDAVFGLAAGIF 60 + D+ H R + WRL+P LL CY A +DR NIGFAKLQ DL D V+GL AG+F Sbjct: 14 LSDSTHDR----VTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTVYGLGAGLF 69 Query: 61 SVGYVALEVPSNLLLVKVGVRKTLLRIMVLWGVVTMLLALVQNQYHLYLLRFLLGAAEGG 120 + Y +PSNL+L ++G R+ + +M++WG ++ + LV+ YLLRFLLG AE G Sbjct: 70 FIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRFLLGVAEAG 129 Query: 121 FFPGILYYLTLWFPDRVRGRMTSLFVMAVPLGGVIAGPLSGLIMDHMQGVHGLHGWQWLF 180 FFPGIL YL WFP R RG++T+LF +AVP+ GVI GPLSG I++ GL GWQW+F Sbjct: 130 FFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHDALGLRGWQWMF 189 Query: 181 ILEGGPAVLLGIAAYFYLADGPQVASWLS-----------ADERRQVAAARLSALLHLLR 229 ++EG P VLLG+ + L + + +WLS A E ++ S + + Sbjct: 190 LIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQRKTITSFSGIFSNPQ 249 Query: 230 VLLLAQHHPAV----------------DADAAETRRRXTEIGWLSGAISVASAIGMXAIG 273 V LL + AV A A+ R IG LS +A M IG Sbjct: 250 VWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSR----IGMLSAVPYLAGCAFMIFIG 305 Query: 274 YSSDRTRERRWHVVCCGLVAAACFIALQAAQDSVLLTVTLLAVASIGIFAILSLFWTIPN 333 SSDR RERRWH+ L+AAA A S L + L +A +G A L +FW +P Sbjct: 306 RSSDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASAALPMFWQLPP 365 Query: 334 AMLEGSAAAGGIALISAIGSFGGAVCPALIGWMNVAT 370 A L + A GIALIS+ GS + P LIGWM T Sbjct: 366 AFLSSATLAAGIALISSFGSIAAFLAPYLIGWMRDTT 402