BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0129.0071.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DRA0195 [IQR] COG1028 Dehydrogenases with different specificitie... 189 7e-48 RSc1769 [IQR] COG1028 Dehydrogenases with different specificitie... 108 1e-23 RSc2753 [IQR] COG1028 Dehydrogenases with different specificitie... 103 3e-22 SA2266 [R] COG4221 Short-chain alcohol dehydrogenase of unknown ... 102 8e-22 mlr6518 [IQR] COG1028 Dehydrogenases with different specificitie... 102 9e-22 >DRA0195 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Dra Deinococcus radiodurans Length = 278 Score = 189 bits (479), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 107/257 (41%), Positives = 155/257 (60%), Gaps = 15/257 (5%) Query: 1 MQVKDKVCVVTGGASGIGEAVARAYADAGARGVVVADLKTSRDRLASV----AGDIDGLA 56 M+ ++K+ VVTGGASGIG A+A + GA + + DR A V A +I Sbjct: 1 MEFQNKIVVVTGGASGIGLALATRFVQEGATVI-------TSDRNAEVGAQKAQEIGARF 53 Query: 57 VTADVGLEEDIKALIAAAEDKYGPVDVFFSNAGLSR-KGQETASDADWDVSWRVHVMSHV 115 + AD+ EE ++A+I + G +D+F SNAG+++ +G ET D WD+ R++VMSHV Sbjct: 54 IPADISREEGVQAIIENVLAQEGRIDLFCSNAGVAQGEGPET-PDKVWDLVHRINVMSHV 112 Query: 116 YAARALVPGMLARGSGYLINTASAAGLLASLNSMPYGVTKNAAVALAEHLAIQYGDRGVR 175 +AAR L+P L RG G+ +NTASAAGLL L+S PY VTK+AA+A AE LA+ YGDRG++ Sbjct: 113 WAARHLLPHFLERGEGHFLNTASAAGLLTELHSAPYAVTKHAALAFAEWLAVTYGDRGIK 172 Query: 176 VSVLCPQSVQTGMTTPGPSAARVDGVLQPGEVARMVIEAMAEERFLILSHPQVQEYMQRK 235 V+ LCP+ V T M P + + E+ +E + + FLI +H + + K Sbjct: 173 VTCLCPEGVWTPMVQNAPILQQT--AITTDELVEKALEVLRADGFLITTHDTTLKSFRNK 230 Query: 236 ATNRERWLSGMRRLRDR 252 A N + W+S MR LR + Sbjct: 231 AENYDVWISKMRHLRTK 247 >RSc1769 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 300 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 95/274 (34%), Positives = 137/274 (50%), Gaps = 46/274 (16%) Query: 2 QVKDKVCVVTGGASGIGEAVARAYADAGARGVVVADLKTSRDRL-ASVAG----DIDGLA 56 Q V V+TGGASG G+A AR A G + +V+AD++ +D L A+VAG ++ + Sbjct: 3 QFAGGVAVITGGASGFGKAFARLGAGLGMK-LVLADIQ--QDALDAAVAGFRAQGVEVIG 59 Query: 57 VTADVGLEEDIKALIAAAEDKYGPVDVFFSNAGLSRKGQ-ETASDADWDVSWRVHVMSHV 115 V DV E D++AL AA +G V++ F+NAG+ G S DWD V++ + Sbjct: 60 VRVDVSREADVQALADAAIRTFGKVNLLFNNAGVGAGGLIWENSQQDWDWVLGVNLHGVI 119 Query: 116 YAARALVPGMLARGS------GYLINTASAAGLLASLNSMPYGVTKNAAVALAEHLAIQY 169 + R P MLA + G+++NTAS AGLL + Y V+K+A VAL E L Y Sbjct: 120 HGVRIFTPLMLAEAAKDPSYAGHIVNTASMAGLLNAPAMGIYNVSKHAVVALTESL---Y 176 Query: 170 GD-----RGVRVSVLCPQSVQTGMT-----------TPGP-------SAARVDGVLQPGE 206 D +R SVLCP V TG+T P + A D + G+ Sbjct: 177 QDLSLVTEQIRCSVLCPYFVPTGITQSHRNRPQDLANAAPPTRSQLVAQAMTDKAVSAGK 236 Query: 207 VA-----RMVIEAMAEERFLILSHPQVQEYMQRK 235 V+ +M +A+ +ERF I SHP +Q + Sbjct: 237 VSAEQVGQMTFDAIRDERFYIYSHPHALAPVQHR 270 >RSc2753 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 265 Score = 103 bits (257), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 71/194 (36%), Positives = 106/194 (54%), Gaps = 3/194 (1%) Query: 6 KVCVVTGGASGIGEAVARAYADAGARGVVVADLK--TSRDRLASVAGDIDGLAVTADVGL 63 KV +VTG GIG A AR +A GAR +V A ++ + AS+ D + L V ADV Sbjct: 15 KVALVTGATQGIGAATARLFARHGARVIVNALVRDAAAEAFAASIGHDGNVLLVQADVRY 74 Query: 64 EEDIKALIAAAEDKYGPVDVFFSNAGLSRKGQETA-SDADWDVSWRVHVMSHVYAARALV 122 + A++AA ++G +DV +NAG++ A S+ADW V + + ARA++ Sbjct: 75 RDQADAMVAAGVARFGGIDVLVNNAGINVFSDPLALSEADWARCLSVDLEGAWHCARAVL 134 Query: 123 PGMLARGSGYLINTASAAGLLASLNSMPYGVTKNAAVALAEHLAIQYGDRGVRVSVLCPQ 182 P MLARG+G ++N AS G + PY V K+ + L L I+Y RG+RV+ + P Sbjct: 135 PHMLARGAGSIVNIASVHGHKIIPGAFPYPVAKHGLIGLTRALGIEYAARGIRVNSISPG 194 Query: 183 SVQTGMTTPGPSAA 196 + T + G +AA Sbjct: 195 LILTPIAEAGFAAA 208 >SA2266 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity Sau Staphylococcus aureus N315 Length = 231 Score = 102 bits (254), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 76/236 (32%), Positives = 123/236 (52%), Gaps = 18/236 (7%) Query: 5 DKVCVVTGGASGIGEAVARAYADAGARGVVVADLKTSRDRLASVAGDI--DGLAVT-ADV 61 DK+ VVTG SGIGEA+A + GA+ V+ ++D+L +VA + D + V DV Sbjct: 6 DKIAVVTGAGSGIGEAIATLLHEEGAKVVLAG---RNKDKLQNVANQLAQDSVKVVPTDV 62 Query: 62 GLEEDIKALIAAAEDKYGPVDVFFSNAG--LSRKGQETASDADWDVSWRVHVMSHVYAAR 119 +E++ L+ A+ +G +D+ ++AG LS K + D +WD V++ +Y A+ Sbjct: 63 TNKEEVDELMKIAQQTFGGLDIVINSAGQMLSSKITDYQVD-EWDSMIDVNIKGTLYTAQ 121 Query: 120 ALVPGMLARGSGYLINTASAAGLLASLNSMPYGVTKNAAVALAEHLAIQYGDRGVRVSVL 179 A +P ML + SG+LIN AS +G + +S Y TK A + + L + GV+V+ + Sbjct: 122 AALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSI 181 Query: 180 CPQSVQTGMTTP-GPSAARVDGVLQPGEVARMVIEAMAEERFLILSHPQVQEYMQR 234 P V T +T PS + L P ++A V+ A+ + + H V E R Sbjct: 182 SPGMVDTAITAAYNPSDRK---KLDPQDIAEAVLYALTQPK-----HVNVNEITVR 229 >mlr6518 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 253 Score = 102 bits (254), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 66/191 (34%), Positives = 110/191 (57%), Gaps = 5/191 (2%) Query: 1 MQVKDKVCVVTGGASGIGEAVARAYADAGARGVVVADLKTS-RDRLASVAGDIDGLAVTA 59 M++++KV ++TG ASG GE +A+ +A GAR VVVADL +R+AS G+ + Sbjct: 6 MRLENKVAIITGAASGFGEGMAKRFAQEGAR-VVVADLNAKGAERVASEIGEA-AIWTQT 63 Query: 60 DVGLEEDIKALIAAAEDKYGPVDVFFSNAGLS-RKGQETASDAD-WDVSWRVHVMSHVYA 117 DV L + ++ AA+ +G +D+ +NAG + R G D + +D+ V++ + +A Sbjct: 64 DVSLRSEFDEMVYAAKSAFGRIDIMVNNAGYTHRNGDMLKVDEETFDLITAVNMKAIYHA 123 Query: 118 ARALVPGMLARGSGYLINTASAAGLLASLNSMPYGVTKNAAVALAEHLAIQYGDRGVRVS 177 A A+VP M +G G ++ TAS AGL Y +K A+ + +A++ + +RV+ Sbjct: 124 ALAVVPIMERQGGGVILTTASTAGLRPRPGLTWYNASKGWAITATKSMAVELAPKNIRVN 183 Query: 178 VLCPQSVQTGM 188 LCP + +TGM Sbjct: 184 CLCPVAGETGM 194