BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0129.0020.p (270 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1571 [IQR] COG1028 Dehydrogenases with different specificities... 326 3e-89 PA3387 [IQR] COG1028 Dehydrogenases with different specificities... 216 5e-56 CC1286 [IQR] COG1028 Dehydrogenases with different specificities... 184 1e-46 mlr3096 [IQR] COG1028 Dehydrogenases with different specificitie... 178 1e-44 RSc1763 [IQR] COG1028 Dehydrogenases with different specificitie... 176 6e-44 >CC1571 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 255 Score = 326 bits (836), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 174/257 (67%), Positives = 202/257 (78%), Gaps = 3/257 (1%) Query: 6 FKDLFSLKGRVALVTGGSRGIGKMIAAGFLAQGAARVYITARKAGPCEATAQELSAAYDG 65 ++LFSL+GRVALVTGGSRGIG MI GFL GA RVYITARKA C+A A+ELS G Sbjct: 1 MQNLFSLEGRVALVTGGSRGIGAMIVKGFLTHGAKRVYITARKAAACDAAAEELSQY--G 58 Query: 66 ECIALPIDISTVEGCEKLAGEIIKREPKLDILVNNAGAAWGADFDEFPESGWDKVMDLNV 125 EC++LP D+ST+EG + LA I +REPKLDILVNNAGAAWGA FDEFPESGWDK +DLN+ Sbjct: 59 ECVSLPGDVSTMEGIQGLAARIKEREPKLDILVNNAGAAWGAGFDEFPESGWDKTVDLNM 118 Query: 126 KSIFFLTKALAKPLRAAATHDKPGKVINIASIDGIFVNPMETYSYAASKAAVIHLTRRMA 185 K+ FFLT+AL LRAAA D+ KVINIASIDG V ETY Y ASKA ++H+T+RMA Sbjct: 119 KTPFFLTQALIGELRAAA-KDRVAKVINIASIDGQSVTKDETYPYGASKAGLLHMTKRMA 177 Query: 186 TRLIKDNINVTAIAPGAFKSDMNRAARDHADEVAKRVPAKRVGSDEDMAGTAIYLASRAG 245 RL +NI V+ IAPGAF SDMN+ ARDHAD VAK +PA R+G EDMAG AIYLASRAG Sbjct: 178 LRLAPENIAVSCIAPGAFASDMNKVARDHADAVAKMIPAGRIGEAEDMAGAAIYLASRAG 237 Query: 246 DYVVGTTIAVDGGVVYA 262 DYV+G + VDGGV +A Sbjct: 238 DYVMGGAVTVDGGVSFA 254 >PA3387 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 256 Score = 216 bits (550), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 119/252 (47%), Positives = 156/252 (61%), Gaps = 6/252 (2%) Query: 10 FSLKGRVALVTGGSRGIGKMIAAGFLAQGAARVYITARKAGPCEATAQELSAAYDGECIA 69 FSL GR+ALVTGGSRGIG+MIA G L GA RV+I AR A C TA LSA G+C A Sbjct: 5 FSLAGRIALVTGGSRGIGQMIAQGLLEAGA-RVFICARDAEACADTATRLSAY--GDCQA 61 Query: 70 LPIDISTVEGCEKLAGEIIKREPKLDILVNNAGAAWGADFDEFPESGWDKVMDLNVKSIF 129 +P D+S+ G +LA + + +LDILVNNAG +WGA + +P SGW+KVM LNV S+F Sbjct: 62 IPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVF 121 Query: 130 FLTKALAKPLRAAATHDKPGKVINIASIDGIFVNPMETYSYAASKAAVIHLTRRMATRLI 189 + L LR +A+ + P +VINI S+ GI + Y+Y SKAA+ L+R +A L+ Sbjct: 122 SCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELV 181 Query: 190 KDNINVTAIAPGAFKSDMNRAARDHADEV---AKRVPAKRVGSDEDMAGTAIYLASRAGD 246 ++INV IAPG F S M R + + + +P R G E+MA AI LA AG Sbjct: 182 GEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAGA 241 Query: 247 YVVGTTIAVDGG 258 Y+ G I +DGG Sbjct: 242 YMTGNVIPIDGG 253 >CC1286 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 260 Score = 184 bits (468), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 108/259 (41%), Positives = 152/259 (58%), Gaps = 11/259 (4%) Query: 6 FKDLFSLKGRVALVTGGSRGIGKMIAAGFLAQGAARVYITARKAGPCEATAQELSAAYDG 65 LF L GRVA+VTGGSRG+G IA GAA V + ARK G +A L+A +G Sbjct: 5 LHKLFDLTGRVAIVTGGSRGLGLQIARALAEYGAA-VALVARKQGELDAAVAALTA--EG 61 Query: 66 EC-IALPIDISTVEGCEKLAGEIIKREPKLDILVNNAGAAWGADFDEFPESGWDKVMDLN 124 + L D+ + L +++R ++DILVNNAGAAWGA +++P GW+KVMDLN Sbjct: 62 RTAVGLVADLGQAGSAQDLTARVLERFGRIDILVNNAGAAWGAPAEDYPLEGWNKVMDLN 121 Query: 125 VKSIFFLTKALAKPLRAAATHDKPGKVINIASIDGI---FVNPMETYSYAASKAAVIHLT 181 V +F LT+A+A R A G V+N+ASI+G+ + + T +Y +K AVI++T Sbjct: 122 VTGLFLLTQAVA---REAFLKQGKGAVVNVASIEGLQGHHHSQLGTIAYNTAKGAVINMT 178 Query: 182 RRMATRLIKDNINVTAIAPGAFKSDMNRAAR-DHADEVAKRVPAKRVGSDEDMAGTAIYL 240 R +A NI V A+APG F S M H D++ ++ P ++G D D+ G A+ L Sbjct: 179 RALAAEWGPRNIRVNAVAPGYFPSKMTMTTLGQHGDDMLRQTPLGKLGGDTDLMGPALLL 238 Query: 241 ASRAGDYVVGTTIAVDGGV 259 AS AG ++ G I VDGG+ Sbjct: 239 ASDAGGHITGQIIVVDGGM 257 >mlr3096 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 271 Score = 178 bits (452), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 107/257 (41%), Positives = 141/257 (54%), Gaps = 5/257 (1%) Query: 6 FKDLFSLKGRVALVTGGSRGIGKMIAAGFLAQGAARVYITARKAGPCEATAQELSA-AYD 64 +LFS+ G+ ALVTG + GIG+M AA + A V I +RK C A + Sbjct: 4 LDELFSVAGKTALVTGAATGIGRMAAAALVKA-GASVMIASRKGEDCIKVANAFNGLGAP 62 Query: 65 GECIALPIDISTVEGCEKLAGEIIKREPKLDILVNNAGAAWGADFDEFPESGWDKVMDLN 124 G D+S+ G L E+ R KL IL+NNAG +WGA + FP S W KV+ +N Sbjct: 63 GRAEGFAGDVSSEAGIAALVAEVKARTGKLGILINNAGVSWGAPLESFPYSAWAKVLGVN 122 Query: 125 VKSIFFLTKALAKPLRAAATHDKPGKVINIASIDGIFVNPMETYSYAASKAAVIHLTRRM 184 V ++F LT+ L L AAA+ P +VIN+ S+ G + YSY ASKAAV HLTR + Sbjct: 123 VTAVFHLTRELLPLLEAAASDADPARVINLGSVMGTQPLADDAYSYTASKAAVHHLTRTL 182 Query: 185 ATRLIKDNINVTAIAPGAFKSDMNRAAR---DHADEVAKRVPAKRVGSDEDMAGTAIYLA 241 A I V A APG F+S M A + A V VP R+G+ +D+AG +YL Sbjct: 183 ALEFAARRITVNAFAPGPFQSRMTAFATGTDEQAKHVGGHVPIGRIGAPDDIAGATLYLC 242 Query: 242 SRAGDYVVGTTIAVDGG 258 SRAG YV G + +DGG Sbjct: 243 SRAGSYVTGAILPIDGG 259 >RSc1763 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 260 Score = 176 bits (446), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 106/260 (40%), Positives = 152/260 (58%), Gaps = 12/260 (4%) Query: 6 FKDLFSLKGRVALVTGGSRGIGKMIAAGFLAQGAARVYITARKAGPC-EATAQELSAAYD 64 K LF L G+ AL+TGGSRG+G IA QGA R+ ++ARKA +A A LS Sbjct: 4 LKHLFDLSGKTALITGGSRGLGLQIAEALGEQGA-RIVLSARKADELKDAQAHLLSLGIA 62 Query: 65 GECIALPIDISTVEGCEKLAGEIIKREPKLDILVNNAGAAWGADFDEFPESGWDKVMDLN 124 + IA D + ++LA E + + +DILVNNAGA WGA ++ P WDKVM+LN Sbjct: 63 ADWIA--ADGAVEADIQRLADEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLN 120 Query: 125 VKSIFFLTKALAKPLRAAATHDKPGKVINIASIDGIFVNP---METYSYAASKAAVIHLT 181 ++ +F LT+ + K + + GK++N+ASI G+ NP ++T +Y SK AV++ T Sbjct: 121 IRGLFLLTQQIGK---RSMIPRQYGKIVNVASIAGLKGNPPGTLDTIAYNTSKGAVVNFT 177 Query: 182 RRMATRLIKDNINVTAIAPGAFKSDMNRAARDH--ADEVAKRVPAKRVGSDEDMAGTAIY 239 R +A K I V AIAPG F S M R + + D++ ++ P R+G +ED+ G A Sbjct: 178 RALAGEWGKYGITVNAIAPGFFPSKMTRGSLEKLGVDKLTEKSPLHRLGDEEDLKGVAAL 237 Query: 240 LASRAGDYVVGTTIAVDGGV 259 AS A ++ G +AVDGGV Sbjct: 238 FASDASKHITGQILAVDGGV 257