BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0127.0057.p         (204 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Rv0825c [K] COG1309 Transcriptional regulator Mtu Mycobacterium ...    59   5e-09
MT0847 [K] COG1309 Transcriptional regulator MtC Mycobacterium t...    59   6e-09

>Rv0825c [K] COG1309 Transcriptional regulator Mtu Mycobacterium
           tuberculosis H37Rv
          Length = 213

 Score = 59.3 bits (142), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 53/202 (26%), Positives = 88/202 (43%), Gaps = 20/202 (9%)

Query: 4   EERRTERRLKLIDAAIEVYGEVGYRGATVKAICEAAELTERYFYESFANSEALLIAAYGH 63
           E R   RR  L+ A +++ G  G    TV+A+C  A LTERYFYESFA+ E  + A Y  
Sbjct: 16  ESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRHAGLTERYFYESFADREHFVRAVYDD 75

Query: 64  VVGHLHEEMTAAAAAAGDDAEMRLRAALTLYFTRLKQHPKPARVFLLEISGISPAVDAVK 123
           V       +T+A            R A+  +   +   P   RV LL    + PA+    
Sbjct: 76  VCTRAMATLTSAQTP---------REAVEQFVELMVDDPVRGRVLLLA-PAVEPALTRSG 125

Query: 124 LDALRVFSDIL---VPPALDPKRSDRGAATSLLSVGMVGAVISIARRWVSKQYPQAVEEV 180
            + +  F ++L   +   +DP          L++  ++GA+  +   +++ +     ++ 
Sbjct: 126 AEWMPNFIELLQRKLSRIVDP------VLQKLVATSLIGALTGLFTAYLNGRLGATRKQF 179

Query: 181 VAIAAS-FCRVALTEADHREDG 201
           +    +     A T A HRE G
Sbjct: 180 IDYCVNMLLSTAATYAPHRERG 201


>MT0847 [K] COG1309 Transcriptional regulator MtC Mycobacterium
           tuberculosis CDC1551
          Length = 239

 Score = 59.3 bits (142), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 53/202 (26%), Positives = 88/202 (43%), Gaps = 20/202 (9%)

Query: 4   EERRTERRLKLIDAAIEVYGEVGYRGATVKAICEAAELTERYFYESFANSEALLIAAYGH 63
           E R   RR  L+ A +++ G  G    TV+A+C  A LTERYFYESFA+ E  + A Y  
Sbjct: 42  ESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRHAGLTERYFYESFADREHFVRAVYDD 101

Query: 64  VVGHLHEEMTAAAAAAGDDAEMRLRAALTLYFTRLKQHPKPARVFLLEISGISPAVDAVK 123
           V       +T+A            R A+  +   +   P   RV LL    + PA+    
Sbjct: 102 VCTRAMATLTSAQTP---------REAVEQFVELMVDDPVRGRVLLLA-PAVEPALTRSG 151

Query: 124 LDALRVFSDIL---VPPALDPKRSDRGAATSLLSVGMVGAVISIARRWVSKQYPQAVEEV 180
            + +  F ++L   +   +DP          L++  ++GA+  +   +++ +     ++ 
Sbjct: 152 AEWMPNFIELLQRKLSRIVDP------VLQKLVATSLIGALTGLFTAYLNGRLGATRKQF 205

Query: 181 VAIAAS-FCRVALTEADHREDG 201
           +    +     A T A HRE G
Sbjct: 206 IDYCVNMLLSTAATYAPHRERG 227