BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0127.0015.p         (403 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF0907 [GEPR] COG0477 Permeases of the major facilitator superfa...    87   9e-17
MA4166 [GEPR] COG0477 Permeases of the major facilitator superfa...    76   1e-13

>AF0907 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu
           Archaeoglobus fulgidus
          Length = 419

 Score = 86.7 bits (213), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 89/361 (24%), Positives = 148/361 (40%), Gaps = 45/361 (12%)

Query: 2   DRFGPRRVQSALLLVAAAGAALFAVSTGFLLLLIARAMIGLGVAAALTAGLKSIILWFPR 61
           D  GPR   +   L+A  G  LFAVS  F + ++ R +IG+GV+           ++ P 
Sbjct: 82  DTKGPRLTTTVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSG----------VYIPT 131

Query: 62  EQVALLNGYMIMLGSLXLTAGLKSIVLWFPRERVALLNGYMVMLGSLGAVTATAPVEHLL 121
                                +K +  WF  +  A L G +  +G++GA+ +  P+  ++
Sbjct: 132 ---------------------IKLLSRWFRVDEFATLTGVLFAVGNMGALVSAYPLATMV 170

Query: 122 VWMGWRQLFEILAVATGTTAILIYLVVP-------ERSVAPSTASATLSSVFSDRRFWRM 174
              GWR  F  +   T   A+  ++ V        E+S      +     V  +   W +
Sbjct: 171 SLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSREGGRFATNFRVVVLNPVVWLI 230

Query: 175 APLSATCIGSAWSLQGLWASPWLTDVEGFDRASLIRQLFIMSIVLSAGAWLFGMTVHCVK 234
           A  +    G     QGLW  P+L DV G  R      L ++ +    GA + G     V 
Sbjct: 231 ATSAFLRYGIVMGYQGLWGGPYLMDVYGMQREEAGGVLMMVGLGTILGAPIIGFLSDKVF 290

Query: 235 RRGIGAETILAIAAVLFIAAECALIL-RASLPSILLWSVVAIVG---TATVVSFAVVADY 290
           R     +  L  A + F      L+   ASL    L+++  ++G    A  V++A++ + 
Sbjct: 291 RT---RKWFLVAAGIGFTFTMAPLVFFTASLTVFQLYAISFLIGLFSAAGPVAYALIKES 347

Query: 291 FPPELAGRANGALNVLHFGWAFLAQYATGLILEQWSANDGHRPVQAYQAAFGFNVALQIA 350
           +P E+ G A   +NV  F    L Q   G +++     DG  P +AY  AF F +A  + 
Sbjct: 348 YPLEVTGLATSIVNVFPFFGGALFQVFMGYLMDTVGMVDGSYPPEAYSLAFSFCLAASVV 407

Query: 351 T 351
           +
Sbjct: 408 S 408


>MA4166 [GEPR] COG0477 Permeases of the major facilitator superfamily Mac
           Methanosarcina acetivorans str.C2A
          Length = 444

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 82/362 (22%), Positives = 155/362 (42%), Gaps = 71/362 (19%)

Query: 2   DRFGPRRVQSALLLVAAAGAALFAVSTGFLLLLIARAMIGLGVAAALTAGLKSIILWFPR 61
           D +G ++      L+AA GA L  V++ F ++LI R +IG+GVA          +++ P 
Sbjct: 66  DSWGVKKTAGVFTLLAAVGAVLTGVASNFTMVLIGRVLIGIGVA----------MVYIPV 115

Query: 62  EQVALLNGYMIMLGSLXLTAGLKSIVLWFPRERVALLNGYMVMLGSLGAVTATAPVEHLL 121
                                +K + +WF +   A ++G ++ +G++GA++A  P+  + 
Sbjct: 116 ---------------------MKVLAIWFKKNEFASMSGVLLAIGNIGALSAAGPLAIMA 154

Query: 122 VWMG-WRQLFEILAVATGTTAILIYLVVP--------------------ERSVAPSTASA 160
              G W+++F +L + +   A+ I+++V                     ER + P     
Sbjct: 155 AAFGDWQKVFLMLGLFSVLLAVAIFVLVKDKPEEMGCPTIPEIEAYEKGERYIPPKAVEK 214

Query: 161 -----TLSSVFSD-RRFWRMAPLSATCIGSAWSLQGLWASPWLTDVEGFDRASLIRQLFI 214
                 L   FS   +FW ++       GS    QGLW  P+  DV G+D+ +    L  
Sbjct: 215 IPMGEALRQTFSSGMKFWPLSIWFFFMYGSLMVYQGLWGGPFFRDVLGWDQGTYAGILSF 274

Query: 215 MSIVLSAGAWLFG-MTVHCVKRRGIGAETILAIAAVLFIAA-----ECALILRASLPSIL 268
           ++I +  G  + G ++   +K R    + +L     ++I         A  + ++    L
Sbjct: 275 IAIGMIFGCPIAGYLSDKVLKSR----KKVLIAGTAVYIVLWGVIWSQAGNITSTTAYTL 330

Query: 269 LWSVVAIVGTATVVSFAVVADYFPPELAGRANGALNVLHFGWAFLAQYATGLILEQWSAN 328
           +  +    G   +VS+A + ++FP  + G A GA N+  F    +    TG ++E    +
Sbjct: 331 IHFLFGFFGGFFIVSYAQIKEWFPASIVGTATGAYNIFPFLGGAIFMTLTGKMME---VS 387

Query: 329 DG 330
           DG
Sbjct: 388 DG 389