BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0125.0003.p         (185 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc2495 [R] COG1234 Metal-dependent hydrolases of the beta-lacta...   173   2e-43
STM1109 [R] COG1234 Metal-dependent hydrolases of the beta-lacta...   161   6e-40
mlr8305 [R] COG1234 Metal-dependent hydrolases of the beta-lacta...   140   1e-33
MT3903 [R] COG1234 Metal-dependent hydrolases of the beta-lactam...    82   5e-16
Rv3796 [R] COG1234 Metal-dependent hydrolases of the beta-lactam...    82   6e-16

>RSc2495 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III Rso Ralstonia solanacearum
          Length = 320

 Score =  173 bits (438), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 87/186 (46%), Positives = 123/186 (66%), Gaps = 8/186 (4%)

Query: 1   MTKEYWELNKFDVETRIEDEGRPDPRKLLIAKDISDDGVVLKTSDVTVTAFRTPHPPITD 60
           MT  + EL  +D+ TRI DEGRP    +L   ++++ G+V++ ++V VT+    HPP++ 
Sbjct: 138 MTARFLELYDYDIRTRIADEGRPPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSP 197

Query: 61  NFAYKFETPDGTIVFSSDTAYNPKLAEFAKGVDVLVHECLYVPAVDRLVATTKNGATLRK 120
            FAY+F+  D +IV S DTA +  L   A G DVLVHE +++P++D+L++T  N  TLR+
Sbjct: 198 AFAYRFDAADRSIVISGDTAPSENLVRLAHGADVLVHEVMHLPSLDKLLSTEPNAKTLRE 257

Query: 121 HLLDSHTSTEDVGRIAAAAGVKTLVLSHFVPG-----DDRQGGGWTRDVKKNYSGRIVVA 175
           HLL SHTS EDVGRIA  A VKTLVLSHFVPG     DD     W   V+ ++ G I+V 
Sbjct: 258 HLLASHTSAEDVGRIATEAKVKTLVLSHFVPGGYPYLDD---AAWLDAVRPHFKGEIIVG 314

Query: 176 KDLMEL 181
           +DL+E+
Sbjct: 315 RDLLEI 320


>STM1109 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III Sty Salmonella typhimurium LT2
          Length = 312

 Score =  161 bits (408), Expect = 6e-40,   Method: Compositional matrix adjust.
 Identities = 85/189 (44%), Positives = 118/189 (62%), Gaps = 10/189 (5%)

Query: 1   MTKEYWELNKFDVETRIEDEGRPDPRKLLIAKDISDDGVVLKTSDVTVTAFRTPHPPITD 60
           MTK  W++   D+  R+E+EG+PDPR L+ A DI   GV+ K   VT++A + PH P  D
Sbjct: 129 MTKASWKVFDRDITLRMEEEGKPDPRNLVKATDIGQ-GVIYKDELVTISALKVPHSPFPD 187

Query: 61  N--FAYKFETPDGTIVFSSDTAYNPKLAEFAKGVDVLVHECLYVPAVDRLVATTKNGATL 118
              FAY+F+T    IVFS DT++ P LA FA+G D+LVHE ++VP+V +L  +  NG TL
Sbjct: 188 GEAFAYRFDTQGKRIVFSGDTSWFPPLATFAQGADILVHEAVHVPSVAKLANSIGNGKTL 247

Query: 119 RKHLLDSHTSTEDVGRIAAAAGVKTLVLSHFVP---GDDRQGGGWTRDVKKNYSGRIVVA 175
            + +   HT+ EDVG+IA  + VK LVLSH VP    DD     W ++  KNY G ++V 
Sbjct: 248 AEAIASHHTTIEDVGKIARESHVKKLVLSHLVPATVADDV----WQQEAMKNYPGPVIVG 303

Query: 176 KDLMELKLP 184
            D M + +P
Sbjct: 304 HDNMTISVP 312


>mlr8305 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III Mlo Mesorhizobium loti
          Length = 227

 Score =  140 bits (354), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 70/149 (46%), Positives = 100/149 (67%), Gaps = 2/149 (1%)

Query: 37  DGVVLKTSDVTVTAFRTPHPPITDNFAYKFETPDGTIVFSSDTAYNPKLAEFAKGVDVLV 96
           +G VL    + VTA R  HPP+TD FA +F+    ++VFS+DTA+ P LA+FAK  D+LV
Sbjct: 67  EGHVLDQHGLKVTALRVHHPPVTDCFALRFDQGGKSVVFSADTAFFPPLADFAKDADILV 126

Query: 97  HECLYVPAVDRLVATTKNGATLRKHLLDSHTSTEDVGRIAAAAGVKTLVLSHFVPGDDRQ 156
           HE +    ++RLVA T NGA L++HLL SH+  E+ GRIA+ AGVK LVL+H +P DD  
Sbjct: 127 HEAMLEEGIERLVARTGNGARLKEHLLASHSFAEEAGRIASEAGVKRLVLNHLIPADDPD 186

Query: 157 GG--GWTRDVKKNYSGRIVVAKDLMELKL 183
            G   W   V+K ++G + +A+D + ++L
Sbjct: 187 IGEADWLAAVRKTWAGDLTIARDGLVVEL 215


>MT3903 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III MtC Mycobacterium tuberculosis CDC1551
          Length = 338

 Score = 82.4 bits (202), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 8/135 (5%)

Query: 45  DVTVTAFRTPHPPITDNFAYKFETPDG--TIVFSSDTAYNPKLAEFAKGVDVLVHECLYV 102
           +V+VTA    H  +   F ++F+      ++ FS DT  +  L   A+G D+LVHE ++ 
Sbjct: 204 NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVF- 262

Query: 103 PAVDRLVATTKNGATLRKHLLDSHTSTEDVGRIAAAAGVKTLVLSHFVPGDDRQGGGWTR 162
                L       A    +L++SHTS E VG +AAAA  K L+LSH+ P DD     W  
Sbjct: 263 ----SLDTAYFGNAFPPNYLVNSHTSAEQVGEVAAAAKPKQLILSHYAP-DDLPDSQWLD 317

Query: 163 DVKKNYSGRIVVAKD 177
            +KKNYSG   +A+D
Sbjct: 318 KIKKNYSGMTTIARD 332


>Rv3796 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III Mtu Mycobacterium tuberculosis H37Rv
          Length = 375

 Score = 82.0 bits (201), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 8/135 (5%)

Query: 45  DVTVTAFRTPHPPITDNFAYKFETPDG--TIVFSSDTAYNPKLAEFAKGVDVLVHECLYV 102
           +V+VTA    H  +   F ++F+      ++ FS DT  +  L   A+G D+LVHE ++ 
Sbjct: 241 NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVF- 299

Query: 103 PAVDRLVATTKNGATLRKHLLDSHTSTEDVGRIAAAAGVKTLVLSHFVPGDDRQGGGWTR 162
                L       A    +L++SHTS E VG +AAAA  K L+LSH+ P DD     W  
Sbjct: 300 ----SLDTAYFGNAFPPNYLVNSHTSAEQVGEVAAAAKPKQLILSHYAP-DDLPDSQWLD 354

Query: 163 DVKKNYSGRIVVAKD 177
            +KKNYSG   +A+D
Sbjct: 355 KIKKNYSGMTTIARD 369