BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0123.0002.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ss... 122 9e-28 DR1151 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Dra D... 109 5e-24 SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso ... 108 9e-24 AF0017_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu... 106 5e-23 APE1484_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ap... 105 1e-22 >SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 256 Score = 122 bits (306), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 77/246 (31%), Positives = 126/246 (51%), Gaps = 24/246 (9%) Query: 25 LNFFDVALINQIADALEEFDNNIEIRASVLAAQGKAFCAGANFGDPARQEQEERAKSDPA 84 LN + L++++ +L+E ++ ++R ++ G+AF AGA+ S Sbjct: 23 LNALNPELVSELDKSLDELESRSDVRVVIITGNGRAFSAGADV-------------SSFI 69 Query: 85 SNLPINHLYVQAVRIFRNK-----KPIVAAIXG------LGLAVSADFRVACPEARFSAN 133 + PI+ + ++ +R NK KPI+A I G L LA++ D R+A A+ Sbjct: 70 TLRPIDVIRLRTLRNVVNKIALYTKPIIAGINGFALGGGLELAMACDIRIASEVAQLGQP 129 Query: 134 FTKLGFHPGFGLTTTLPELIGKNNAELMFYTSRRVTGEEAYRWGLANVLVPQDQVRAEAM 193 +G PG G T LP L+GK A+LM YT V+ E+AY+ GL +++VP ++ E Sbjct: 130 EINIGIIPGAGGTQRLPRLVGKGKAKLMIYTGDMVSAEDAYKMGLVDLVVPSNRFEEEVR 189 Query: 194 KLAQEIAECSPLGLVSTRATMRAGLADRVLAATNHELAEQTKLRATEDFKEGVKATAERR 253 ++A +IAE SP+ L++ + + G + E L T+D +EGVKA E+R Sbjct: 190 RVALKIAEKSPISLLAAKLAIELGYESNIWTGQTLESTLFGLLFTTKDVEEGVKAFLEKR 249 Query: 254 VANFKG 259 FKG Sbjct: 250 KPQFKG 255 >DR1151 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Dra Deinococcus radiodurans Length = 302 Score = 109 bits (273), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 85/266 (31%), Positives = 131/266 (49%), Gaps = 18/266 (6%) Query: 3 KYTDIGVETHGHVGLIEIRKP-PLNFFDVALINQIADALEEFDNNIEIRASVLAAQG-KA 60 ++ +I ++ HG + ++ + +P LN + ++++A A + N+ E+ A ++ G KA Sbjct: 45 EFENITIDQHGPIAVLTVNRPKALNALNGTTLSELAMAADLIANDPEVGALIVTGAGDKA 104 Query: 61 FCAGANFGDPARQEQEERAKSDPASNLPINHLYVQAVRIFRNKK-PIVAAIXG------L 113 F AGA+ + A E P + ++ L A+ N P++AAI G L Sbjct: 105 FVAGADISELAGLEG-------PFAGRDMSLLGQDAMTQLSNLPIPVIAAIGGYALGGGL 157 Query: 114 GLAVSADFRVACPEARFSANFTKLGFHPGFGLTTTLPELIGKNNAELMFYTSRRVTGEEA 173 LA+ D R+A P AR LG PGF T LP LIG A + T+R++ EEA Sbjct: 158 ELALCCDIRIASPRARMGLPEVTLGLLPGFAGTQRLPRLIGAGRALDLMLTARQIGAEEA 217 Query: 174 YRWGLANVLVPQDQVRAEAMKLAQEIAECSPLGLVSTRATMRAGLADRVLAATNHELAEQ 233 GL N + D +A ++A++I + PL + + +R GLA + A E Sbjct: 218 LSMGLVNYVA--DDPLQKAREVAEQIVKNGPLAISLVKEAVRRGLATDLEAGMEIEADLF 275 Query: 234 TKLRATEDFKEGVKATAERRVANFKG 259 AT DFKEG KA E+R A FKG Sbjct: 276 GLAFATSDFKEGTKAFLEKRPAEFKG 301 >SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 266 Score = 108 bits (271), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 81/264 (30%), Positives = 137/264 (51%), Gaps = 30/264 (11%) Query: 4 YTDIGVETHGHVGLIEIRKP-PLNFFDVALINQIADALEEFDNNIEIRASVLAAQGKAFC 62 Y+ I +E ++G+I++ +P LN + +++++ D L + DN+ +I+ ++ GKAF Sbjct: 9 YSTIQIEVIDNIGIIKLNRPDKLNAINFQMVDELVDVLNKLDNDDKIKVVIITGNGKAFS 68 Query: 63 AGANFGDPARQEQEERAKSDPASNLPINHLYVQAVRIFRNKKPIVAAIXG------LGLA 116 AGA+ + EE K ++P+ + +R F KKP++AA+ G L LA Sbjct: 69 AGADVKEMLETPLEEIMKK---GHMPL----WEKLRTF--KKPVIAALNGITAGGGLELA 119 Query: 117 VSADFRVACPEARFSANFTKLGFHPGFGLTTTLPELIGKNNAELMFYTSRRVTGEEAYRW 176 ++ D +A A+ LG PG G T L ++GK A + T + + +EA R+ Sbjct: 120 MACDIIIASESAKLGQPEINLGIMPGAGGTQRLTRVLGKYKAMELVLTGKLIDSKEAERY 179 Query: 177 GLANVLVPQDQVRAEAMKLAQEIAECSPLGLV-STRATMRAGLADRVLAA------TNHE 229 GL N +VP + + EA++LA+EIAE + ++ + A RA D +L N Sbjct: 180 GLVNKVVPDNSLIDEAIRLAREIAEKPIISIILAKEAVARAW--DTLLQQGLDFERRNFY 237 Query: 230 LAEQTKLRATEDFKEGVKATAERR 253 LA TK + KEG++A E+R Sbjct: 238 LALNTK-----EAKEGMRAFLEKR 256 >AF0017_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 259 Score = 106 bits (265), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 77/264 (29%), Positives = 123/264 (46%), Gaps = 14/264 (5%) Query: 4 YTDIGVETHGHVGLIEIRKPP-LNFFDVALINQIADALEEFDNNIEIRASVLAAQGKAFC 62 Y + VE G VG++++ +P N + + ++ DAL+ + + E+RA V+A +GK FC Sbjct: 3 YEFVKVEKEGKVGVLKLNRPRRANALNPTFLKEVEDALDLLERDEEVRAIVIAGEGKNFC 62 Query: 63 AGANFGDPARQEQEERAKSDPASNLPINHLYVQAVRIFRNKKPIVAAIXG------LGLA 116 AGA+ A E + + H + + + KP++AAI G LA Sbjct: 63 AGADIAMFASGRPEMVTEFSQ-----LGHKVFRKIEML--SKPVIAAIHGAAVGGGFELA 115 Query: 117 VSADFRVACPEARFSANFTKLGFHPGFGLTTTLPELIGKNNAELMFYTSRRVTGEEAYRW 176 ++ D RV A LG PG+G T L +G + + + R + EEA Sbjct: 116 MACDLRVMSERAFLGLPELNLGIIPGWGGTQRLAYYVGVSKLKEVIMLKRNIKPEEAKNL 175 Query: 177 GLANVLVPQDQVRAEAMKLAQEIAECSPLGLVSTRATMRAGLADRVLAATNHELAEQTKL 236 GL + PQ++ E MKLA+E+AE PL + + + G + E + Sbjct: 176 GLVAEVFPQERFWDEVMKLAREVAELPPLAVKYLKKVIALGTMPALETGNLAESEAGAVI 235 Query: 237 RATEDFKEGVKATAERRVANFKGR 260 T+D EG++A RR NF+GR Sbjct: 236 ALTDDVAEGIQAFNYRRKPNFRGR 259 >APE1484_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ape Aeropyrum pernix Length = 257 Score = 105 bits (261), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 78/260 (30%), Positives = 123/260 (47%), Gaps = 16/260 (6%) Query: 9 VETHGHVGLIEIRKP-PLNFFDVALINQIADALEEFDNNIEIRASVLAAQGKAFCAGANF 67 V + I + +P LN +I +++ AL+E + ++RA +L G+AF AGA+ Sbjct: 6 VRVEKPIAWIVLNRPDKLNAISPKMIMELSQALDELEERSDVRAVILTGAGRAFSAGADV 65 Query: 68 GDPARQEQEERAKSDPASNLPINHLYVQ-AVRIFRNKKPIVAAIXG------LGLAVSAD 120 A+ P L + + + ++I KP++ AI G L LA+S D Sbjct: 66 --------TAFAQVTPIDILRFSRKFQELTLKIQFYTKPVIVAIKGYALGGGLELAMSGD 117 Query: 121 FRVACPEARFSANFTKLGFHPGFGLTTTLPELIGKNNAELMFYTSRRVTGEEAYRWGLAN 180 R+A +A LGF PG G T L L G A+ + T + +A + G+ N Sbjct: 118 IRIASEDAMLGQPEINLGFIPGAGGTQRLARLAGPARAKELIMTGDMIPASDAEKMGIVN 177 Query: 181 VLVPQDQVRAEAMKLAQEIAECSPLGLVSTRATMRAGLADRVLAATNHELAEQTKLRATE 240 +VP + + EA LA ++AE P+ L + + + GL + A E + + L +TE Sbjct: 178 RVVPPELLEQEASSLALKLAEKPPIALAAAKYAIDFGLESNIWAGLQLEASLFSVLFSTE 237 Query: 241 DFKEGVKATAERRVANFKGR 260 D EGV A E+R FKGR Sbjct: 238 DVIEGVTAFLEKRKPKFKGR 257