BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0121.0007.p (426 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 99 1e-20 mlr2429 [GEPR] COG0477 Permeases of the major facilitator superf... 98 5e-20 AF0367 [GEPR] COG0477 Permeases of the major facilitator superfa... 91 5e-18 BS_ycxA [GEPR] COG0477 Permeases of the major facilitator superf... 87 5e-17 BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superf... 85 4e-16 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 99.4 bits (246), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 101/406 (24%), Positives = 193/406 (47%), Gaps = 23/406 (5%) Query: 35 VLALCFVLSVLGRGLSDSFTVFLKPISENFGWDRASVVSVYSLTWLASGLTAPLVGRLFD 94 ++A+ F+ + +G+ SF F++P F DR S+ + +L+++ G++ PL+G+L D Sbjct: 11 IVAVTFLTFLAVQGVRLSFGAFVQPWETEFSMDRGSISLISTLSFIVYGISQPLIGKLVD 70 Query: 95 RSGPRVVYALGLSLLGCAFLVASRAQALWQFQLSVGLCVGFGTALIGNVSNSILLGRWFG 154 R G R + + L+G +F++ + A W + G+ V G NV+ ++++ WF Sbjct: 71 RLGARFILSCSTLLVGVSFVLTTMATQPWHLFILYGVVVSIGVGGASNVAATVVITNWFN 130 Query: 155 PRLPTAMAVMYSATGAGLLLLLPLSQVLIDRIGWREAYQVFGIGALCLLVPLVFLPWR-- 212 + A ++ + GAG ++L+P S +LI + W+ + G ++ P+V L R Sbjct: 131 KKRGLAFGIIEAGFGAGQMILVPGSLMLIQWLDWKATVVILGFFLAVIVFPIVLLLLRNH 190 Query: 213 -----LLAGGSPHIVRKSESSLADEGWTLLSAMRHHAFWALFSTFFFTAIAMYALTAQIV 267 + G ++ +S ++ S R FW L F AI + T + Sbjct: 191 PSEKQVEPIGGVREEEETNTSPNSATFSNWSVFRMRPFWFLVLPF---AICGFTTTGLMD 247 Query: 268 AYLI----DVGFPPLQAATAWGFSGVALFVG--MLGVSTLDGIIGRR-PSVLFSYGVSIL 320 +LI D GF +T+ + V+L G ++G+ L G+I R S F + + + Sbjct: 248 THLIPLSHDHGF-----STSVTSAAVSLLAGFNIVGI-LLSGVIADRWSSRKFLFLLYVA 301 Query: 321 GIILLWLLQWYPNYWLLTGFIICFGSMIGSRGPLITATALKIFRGERVGTIYGTIMIGSG 380 + L +L + LL GF I FG + + A + F+ +G + G + + Sbjct: 302 RALSLVILVHSHDPLLLLGFAILFGLVDFATVAPTQLLATQYFKRYSIGLMIGWLFLSHQ 361 Query: 381 LGSGLGSWGGGLIHDWTHSYNPLIAFALVNVVLGLIPFLVVPALRR 426 +GS LG++ GL+++ T SY + ++V +++ I L +P + Sbjct: 362 VGSALGAYVPGLLYEQTGSYTVSLYVSIVILIVAAICNLFLPEPNK 407 >mlr2429 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 400 Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 105/368 (28%), Positives = 170/368 (46%), Gaps = 8/368 (2%) Query: 35 VLALCFVLSVLGRGLSDSFTVFLKPISENFGWDRASVVSVYSLTWLASGLTAPLVGRLFD 94 ++A ++S + G S +FL+P++ + W RA + S +L +L GL G L D Sbjct: 9 IVATGALMSCVAIGTMFSLAIFLEPMALDTQWSRAGISSAMTLNFLVMGLGGFAWGALSD 68 Query: 95 RSGPRVVYALGLSLLGCAFLVASRAQALWQFQLSVGLCVGFGTALIGNVSNSILLGRWFG 154 R G R+V A+G LLG A +VASRA +L FQ+S G+ VG + L WF Sbjct: 69 RFGARIVVAIGAVLLGLALVVASRAGSLLTFQISYGVLVGLAASAF-FAPMIALTTAWFD 127 Query: 155 PRLPTAMAVMYSATGAGLLLLLPLSQVLIDRIGWREAYQVFGIGALCLLVPLVFLPWRLL 214 A++++ + G + + P ++ LI WR A GI A LL+P V L + Sbjct: 128 TNRSLAVSLVSAGMGVAPMTISPFARWLISAYEWRTAMFDIGIMAWVLLLPAVLLVRQ-- 185 Query: 215 AGGSPHIVRKSESSLAD-EGWTLLSAMRHHAFWALFSTFFFTAIAMYALTAQIVAYLIDV 273 P + + + +A+ G ++ A+R F L TFF A +V+Y + Sbjct: 186 -PPKPAVAAGASAPVAEGAGMSVAQALRSPQFIVLGLTFFTCCAAHSGPIFHMVSYAMLC 244 Query: 274 GFPPLQAATAWGFSGVALFVGMLGVSTLDGIIGRRPSVLFSYGVSILGIILLWLLQWYPN 333 G P+ A T + G+A G L L +G +P ++ + + I + Sbjct: 245 GVAPMAAVTIYSVEGLAGLGGRLLYGVLADRLGVKPVLITGLVIQAVVIAAYLSVSQLDQ 304 Query: 334 YWLLTGFIICFGSMIGSRGPLITATALKIFRGERVGTIYGTIMIGSGLGSGLGSWGGGLI 393 +++L + FG+ G PL A + F +GT++G + S LG LG GG++ Sbjct: 305 FYVLA---VIFGATYGGVMPLYAVLAREYFGQRILGTVFGAATMLSSLGMALGPLAGGMV 361 Query: 394 HDWTHSYN 401 D SY+ Sbjct: 362 FDAYASYH 369 >AF0367 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 397 Score = 90.9 bits (224), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 115/391 (29%), Positives = 167/391 (42%), Gaps = 25/391 (6%) Query: 48 GLSDSFTVFLKPISENFGWDRASVVSVYSLTWLASGLTAPLVGRLFDRSGPRVVYALGLS 107 G+ +++VF+ P+ FGW + +S+ L L GR DR GPR V LG Sbjct: 19 GIVYAWSVFVNPLMNTFGWSKTIASLPFSIFLLIFALMMVPAGRTQDRIGPRKVAMLGGV 78 Query: 108 LLGCAFLVA---SRAQALWQFQLSVGLCVGFGTALIGNVSNSILLGRWFGPRLPTAMAVM 164 LLG FL++ Q+ + S G+ G G L G + +WF R+ A ++ Sbjct: 79 LLGVGFLLSGLIESIQSPYWLIFSYGVIAGAGCGL-GYACPIPVARKWFPERVGLATGLV 137 Query: 165 YSATGAGLLLLLPLSQVLIDRIGWREAYQVFGIGALCLLVPLVFLPWRLLAGGSPHIVRK 224 G L+ PL ++LID G + + G+ LL+ VF L V+ Sbjct: 138 VMGFGMSALIFAPLERILIDTYGISTTFYILGV---ILLIVAVFAASLLSNPPELPAVQA 194 Query: 225 SESSLAD--EGWTLL---SAMRHHAFWALFSTFFFTAIAMYALTAQIVAYLIDVGFPPLQ 279 S + + G L +R + F+ L+ +FFF A+A + I Y + G PL Sbjct: 195 SNPAKVEVVTGKPELGPSEMLRDYRFYVLWLSFFFMALAGLMVIGHIAPYAQERGLEPLA 254 Query: 280 AATAWGFSGVALFVGMLGVSTLDGIIGRRPSVLFSYGVSILGIILLWLLQWYPNYWL-LT 338 AA A VA VG G L IGR ++ + I GI L+ +P+ L L Sbjct: 255 AAFAVSILSVANAVGRPGAGALSDKIGRAMTMFVLF--LIQGITLI----AFPHVALTLI 308 Query: 339 GFIIC---FGSMIGSRGPLITATALKIFRGERVGTIYGTIMIGSGLGSGLGSWGGGLIHD 395 IC G G+ L + F + +G YG + G+G +G G + D Sbjct: 309 TIYICAAIIGFNYGANFSLFPSATGDFFGTKNLGVNYGLVFTSYGVGGLVGPIMAGYVFD 368 Query: 396 WTHSYNPLIAFALVNVVLGLIPFLVVPALRR 426 T SY IAF LV VL LI + LRR Sbjct: 369 VTGSYE--IAF-LVAGVLALIAAFMSFLLRR 396 >BS_ycxA [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 409 Score = 87.4 bits (215), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 98/395 (24%), Positives = 168/395 (42%), Gaps = 18/395 (4%) Query: 35 VLALCFVLSVLGRGLSDSFTVFLKPISENFGWDRASVVSVYSLTWLASGLTAPLVGRLFD 94 V FV ++ +SF F+ P+++ F DR+ + S+ + +G+ VG D Sbjct: 11 VFLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRSLISVSVSIFMITTGIVQFFVGFFID 70 Query: 95 RSGPRVVYALGLSLLGCAFLVASRAQALWQFQLSVGLCVGFGTALIGNVSNSILLGRWFG 154 R R + ALG + +FLV + + F G+ G G + V+ + WF Sbjct: 71 RFSVRKIMALGAVCISASFLVLPYSPNVHVFSAIYGVLGGIGYSCAVGVTTQYFISCWFD 130 Query: 155 PRLPTAMAVMYSATGAGLLLL-LPLSQVLIDRIGWREAYQVFGIGALCLLVPLVFLPWRL 213 A+A++ +A AGL++ P+ GW+ Y + GI +LVPL+ + Sbjct: 131 THKGLALAILTNANSAGLVVSPPPIWAAAPYHAGWQSTYTILGIVMAAVLVPLLVFGMKH 190 Query: 214 LAGGSPHIVRKSESSLADEGWTLLSAMR--HHAFWALFSTFFFTAIAMYALTAQIVAYLI 271 V+KS W ++ R H ++ +F+ F M + A +V L Sbjct: 191 PPHAQAETVKKSYD--WRGFWNVMKQSRLIHILYFGVFTCGF----TMGIIDAHLVPILK 244 Query: 272 DVGFPPLQAATAWGFSGVALFVGMLGVSTLDGIIGRRP---SVLFSYGVSILGIILLWLL 328 D + A G + +G L L ++G R S+LF + L +L+ +L Sbjct: 245 DAHVSHVNGMMAA--FGAFIIIGGLLAGWLSDLLGSRSVMLSILFFIRLLSLICLLIPIL 302 Query: 329 QWYPNYWLLTGFIICFGSMIGSRGPLITATALKIFRGERVGTIYGTIMIGSGLGSGLGSW 388 + + GFI+ FG PL A+ + ++ +G++ G + L + Sbjct: 303 GIHHSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGLIGSLLGINFFIHQVAGALSVY 362 Query: 389 GGGLIHDWTHSYNPLIAFALVNV----VLGLIPFL 419 GGL D TH Y ++A +V V V+ L+PFL Sbjct: 363 AGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFL 397 >BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 416 Score = 84.7 bits (208), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 97/393 (24%), Positives = 174/393 (44%), Gaps = 32/393 (8%) Query: 27 KQSRVALNVLALCFVLSVLGRGLSDSFTVFLKPISENFGWDRASVVSVYSLTWLASGLTA 86 K+ A ++++ F++ + +G+ SF F++P F DR+++ + +++++ G++ Sbjct: 2 KRLHYAWIIVSVTFLILLAVQGVRLSFGAFVEPWERQFSIDRSTISLISTVSFIVYGISQ 61 Query: 87 PLVGRLFDRSGPRVVYALGLSLLGCAFLVASRAQALWQFQLSVGLCVGFGTALIGNVSNS 146 P++GRL D+ G R V A L G + + + WQ L GL V G NV+ S Sbjct: 62 PVIGRLVDKWGARAVLAWSALLTGVSIFLTYLVTSPWQLFLLYGLGVSLGVGGASNVAAS 121 Query: 147 ILLGRWFGPRLPTAMAVMYSATGAGLLLLLPLSQVLIDRIGWREAYQVFGIGALCLLVPL 206 +L+ WF + A +M + GAG +LL+P S +LI W+ V G+ + ++ P Sbjct: 122 VLVVNWFSKKRGLAFGIMEAGFGAGQMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVFPA 181 Query: 207 VFLPWRLLAGGSPH----------IVRKSESSLADEGWTLLSAMRHHAFWALFSTFF--- 253 L R +P + E++ ++ R FW L F Sbjct: 182 ALLMLR----NNPSEKNTEPIGGLAASEKETAPKTTALSVAGMFRMRQFWFLIFPFLICG 237 Query: 254 FTAIAMYALTAQIVAYLIDVGFPPLQAATAWGFSGVALFVGM-LGVSTLDGIIGRRPS-- 310 FT + + + ++ + D GF + A V+L G + L GI+ R S Sbjct: 238 FTTVGL--MDTHLIPFSHDHGFSTTVTSAA-----VSLLAGFNIAGILLSGIVADRWSSR 290 Query: 311 --VLFSYGVSILGIILLWLLQWYPNYWLLTGFIICFGSMIGSRGPLITATALKIFRGERV 368 + Y V L I+ +L + +LL F I FG + + A + F+ + Sbjct: 291 KILCILYAVRALSIV---ILIYSHEPYLLLAFAILFGLVDFATVAPTQMLATQYFQNYSI 347 Query: 369 GTIYGTIMIGSGLGSGLGSWGGGLIHDWTHSYN 401 G + G + + +GS LG++ G+I+ T Y Sbjct: 348 GLMIGWLSLAHQIGSALGAYVPGVIYTVTGEYT 380