BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0120.0113.p (487 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl171 [S] COG2120 Uncharacterized proteins, LmbE homologs Atu A... 300 6e-81 AGl170 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphoryla... 276 8e-74 BMEII0827 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphor... 273 5e-73 BMEII0826 [S] COG2120 Uncharacterized proteins, LmbE homologs Bm... 266 7e-71 YPO3115 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphoryl... 139 2e-32 >AGl171 [S] COG2120 Uncharacterized proteins, LmbE homologs Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 236 Score = 300 bits (767), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 138/222 (62%), Positives = 171/222 (77%) Query: 265 QRGVTGMRALQLARPGDQLSMLCLGAHSDDIEIGAGATLLGLIERGIKLDVHWCVLSGGA 324 +R M+ + LA GD+LS+LCLGAHSDDIEIG G T+L L+ +G+ LDV+WCVLS G Sbjct: 14 KRQAAAMKNMSLASAGDRLSILCLGAHSDDIEIGVGGTVLSLLSKGVLLDVYWCVLSAGN 73 Query: 325 IREAEARASAADFLCEAASANVEVLSFPDGFFPERGEAIKEWFESLKRRVEPDVILTHRR 384 R EAR+SA FL +AAS ++E+ SF D +FP + IK W +L+ +V PD+I TH R Sbjct: 74 ERALEARSSAEAFLAKAASYSIELASFQDSYFPSQSREIKSWLLTLRDKVSPDIIFTHSR 133 Query: 385 DDAHQDHRQVCRLTWNTFRDHQILEYEIPKWDGDFGQPNVYMPVSAAALDRKIELLLKHF 444 +DAHQDHR++ RLT N FR+H ILEYEIPKWDGDFG+ N Y+P+S A++ K+ELLL+HF Sbjct: 134 EDAHQDHREINRLTSNIFRNHLILEYEIPKWDGDFGRRNAYVPLSEDAMNMKVELLLQHF 193 Query: 445 GTQRSKQWFDADTFRGLARIRGMECRATERFAEAFFGRKLTL 486 GTQRSK WFDADTFRGLAR+RGMECRA RFAEAF RKLT Sbjct: 194 GTQRSKDWFDADTFRGLARLRGMECRAPTRFAEAFTVRKLTF 235 >AGl170 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 270 Score = 276 bits (706), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 125/194 (64%), Positives = 158/194 (81%), Gaps = 1/194 (0%) Query: 1 MKVVLFCGGLGTRIREYSESIPKPMVPIGHQPILWHVMQYYSQYDHNDFVLCLGYKANVI 60 MKVVLFCGG GTRIREYSES+PKP++P+G QPI+ HVMQYY++Y H DF+LCLGYKA+VI Sbjct: 1 MKVVLFCGGRGTRIREYSESVPKPLIPLGSQPIMRHVMQYYARYGHEDFILCLGYKAHVI 60 Query: 61 KDYFLNYRATANSDCVISEYGKKVELIGEHQPDWRVSLVDTGTWRNIGQRLLAVRHLVKD 120 K++FLN R + +DCVIS G+ VEL+ E DWRVSL+DTG WRNIG+RL AVRH +K Sbjct: 61 KEFFLNSRPESYADCVISSPGR-VELLEELPRDWRVSLIDTGIWRNIGERLWAVRHHLKG 119 Query: 121 EEMFFANYSDGLTDAPLPDMIQKFKESGKIGCFVAIHPPISFHLAEFDAQGSVQRIRSSQ 180 E+MF ANYSDGLTD L DMI +F++S K+ CF+A+ PP+++HLAE D G V+ RSS+ Sbjct: 120 EKMFLANYSDGLTDVDLDDMIAQFEKSDKLACFLAVRPPLTYHLAEIDESGKVREFRSSE 179 Query: 181 ESEIWINGGYFIFR 194 S++WINGGYF+ R Sbjct: 180 TSDMWINGGYFLMR 193 >BMEII0827 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Bme Brucella melitensis Length = 295 Score = 273 bits (699), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 120/193 (62%), Positives = 154/193 (79%) Query: 1 MKVVLFCGGLGTRIREYSESIPKPMVPIGHQPILWHVMQYYSQYDHNDFVLCLGYKANVI 60 MKVVLFCGGLGTRIREYSE+IPKPM+P+GHQPIL HVM+YYS Y HNDFVLCLGYKANV+ Sbjct: 27 MKVVLFCGGLGTRIREYSENIPKPMIPLGHQPILHHVMEYYSDYGHNDFVLCLGYKANVV 86 Query: 61 KDYFLNYRATANSDCVISEYGKKVELIGEHQPDWRVSLVDTGTWRNIGQRLLAVRHLVKD 120 KD+FL R +DCV+S+ G+ V+L+ E DW V+L+DTG WRNIG+RL + R V + Sbjct: 87 KDFFLTIRPQTFADCVVSDGGRNVQLLEEVDRDWSVTLLDTGIWRNIGERLWSARSHVMN 146 Query: 121 EEMFFANYSDGLTDAPLPDMIQKFKESGKIGCFVAIHPPISFHLAEFDAQGSVQRIRSSQ 180 E++F ANYSDGL+D L +M Q+F+ SGK+ CF+A+ PP+++HLA+ G V+ R+S Sbjct: 147 EDIFLANYSDGLSDVDLDNMTQRFRASGKVACFLAVRPPLTYHLADIAEGGDVRAFRTSN 206 Query: 181 ESEIWINGGYFIF 193 S+IWINGGYF+F Sbjct: 207 TSDIWINGGYFLF 219 >BMEII0826 [S] COG2120 Uncharacterized proteins, LmbE homologs Bme Brucella melitensis Length = 218 Score = 266 bits (680), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 131/212 (61%), Positives = 149/212 (70%) Query: 276 LARPGDQLSMLCLGAHSDDIEIGAGATLLGLIERGIKLDVHWCVLSGGAIREAEARASAA 335 LA PG L +LCLGAHSDDIEIG G TLL LIE G L V WCVLSG R AEA ASA Sbjct: 7 LANPGRPLELLCLGAHSDDIEIGCGGTLLHLIETGTPLHVEWCVLSGNEQRRAEAEASAR 66 Query: 336 DFLCEAASANVEVLSFPDGFFPERGEAIKEWFESLKRRVEPDVILTHRRDDAHQDHRQVC 395 DFL + V SF D +FP AIKEW + + R +PD++ TH DAHQDHR V Sbjct: 67 DFLRGMDRFQLHVASFADSYFPAESRAIKEWLIAQRGRGQPDIVFTHYHGDAHQDHRTVN 126 Query: 396 RLTWNTFRDHQILEYEIPKWDGDFGQPNVYMPVSAAALDRKIELLLKHFGTQRSKQWFDA 455 LTWN FRD ILEYEIPKWDGD G+PN Y + A+ ++RKI+LL+KHFGTQRSK WF Sbjct: 127 ELTWNLFRDQLILEYEIPKWDGDLGRPNAYSALPASIMERKIDLLMKHFGTQRSKDWFGP 186 Query: 456 DTFRGLARIRGMECRATERFAEAFFGRKLTLI 487 +TFRGLAR+RGMECRA E +AEAF RKL L Sbjct: 187 ETFRGLARLRGMECRAPETYAEAFHARKLRLF 218 >YPO3115 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Ype Yersinia pestis Length = 261 Score = 139 bits (349), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 80/200 (40%), Positives = 109/200 (54%), Gaps = 9/200 (4%) Query: 1 MKVVLFCGGLGTRIREYSESIPKPMVPIGHQPILWHVMQYYSQYDHNDFVLCLGYKANVI 60 +K V+ GGLGTR+ E + PKPMV IG +PILWH+M+ YS Y NDFV+C GYK VI Sbjct: 5 VKAVILAGGLGTRLSEETVVKPKPMVEIGGKPILWHIMKLYSSYGINDFVICCGYKGYVI 64 Query: 61 KDYFLNYRATANSDCVISEYGKKVELIGEHQPDWRVSLVDTGTWRNIGQRLLAVRHLVKD 120 K+YF NY SD ++ + + W V+LVDTG G RL V+ VKD Sbjct: 65 KEYFANYFMHM-SDITFCMRDNEMIVHQKRVEPWNVTLVDTGEDSMTGGRLRRVKDYVKD 123 Query: 121 EEMFFANYSDGLTDAPLPDMIQKFKESGKIGCFVAIHPPISFHLAEFDAQGSVQRIRSSQ 180 +E F Y DG++D + ++I+ K GK A +PP F + +++RS + Sbjct: 124 DEAFCFTYGDGVSDVNIAELIEFHKSHGKQATLTATYPPGRFGALDIKD----KQVRSFK 179 Query: 181 ESE----IWINGGYFIFRNK 196 E INGGYF+ K Sbjct: 180 EKPKGDGALINGGYFVLSPK 199