BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0119.0024.p (364 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO0278 [E] COG0626 Cystathionine beta-lyases/cystathionine gamm... 358 2e-98 SMc02117 [E] COG0626 Cystathionine beta-lyases/cystathionine gam... 349 6e-96 mll8145 [E] COG0626 Cystathionine beta-lyases/cystathionine gamm... 344 1e-94 AGc2902 [E] COG0626 Cystathionine beta-lyases/cystathionine gamm... 337 3e-92 BMEI1213 [E] COG0626 Cystathionine beta-lyases/cystathionine gam... 334 2e-91 >YPO0278 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases Ype Yersinia pestis Length = 393 Score = 358 bits (918), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 174/380 (45%), Positives = 243/380 (63%), Gaps = 37/380 (9%) Query: 16 ATRLVTAGRDTKAQKGFVNPPVFHGSTVLYPTAEDLHAHRAEFTYGRHGSPTTRALQDVL 75 +T++ GR+ + Q GFVN P++ GSTV++ T +D+ +RA F YG G+PT L+ Sbjct: 12 STQITQLGRNPQEQTGFVNTPIYRGSTVIFNTVDDIVNNRAVFNYGTAGTPTIANLESAW 71 Query: 76 MALEGPQCAGVGLAPSGLAAISTTLLAVLKAGEHLLVCDNAYRPTRNFCDNMLKRYGIET 135 AL G AG ++PSGL I+ LL LKAG+HLL+ D+ Y+PTR C ++ R G+ET Sbjct: 72 TALAG--AAGTVISPSGLGVIALALLTTLKAGDHLLMPDSVYKPTRLLCAGLIARMGVET 129 Query: 136 SYFDPLVDAGIETLFKPNTRAVLIEAPGSQTFEMPDVRAISAVAHARGALMIDDNTWATP 195 +Y+DPL+ A IETL KPNT + +E+PGSQ+FE+ D+ ++A+ RG I DNTWA+P Sbjct: 130 TYYDPLIGAEIETLMKPNTSTLFLESPGSQSFEIQDIPMMTAITKRRGIATIIDNTWASP 189 Query: 196 LYHRSLEQGVDISMQAATKYIGGHSDIMFGTIAANAKAWPLIQEAIRLLGVCAGPDDVYL 255 L+ + + G D+S++A TKY+GGHSD++ G ++AN + WP ++E + + G +D +L Sbjct: 190 LFFAAHKHGCDLSLEAGTKYLGGHSDLLMGLVSANEQWWPKLRETYDSMAMLPGAEDCFL 249 Query: 256 ALRX----------------------------------ALDTDPGHAIWKRDFTGASGLF 281 ALR A PGH WKRDFTG+SGLF Sbjct: 250 ALRGLRTLHLRIKEAEKRGLEMAQWLKERPEVLRVLHPAFPDCPGHEFWKRDFTGSSGLF 309 Query: 282 SIVLKP-VPQTAVDAMLNALTLFGMGFSWGGFESLAIPFDCSDYRTATKWSPGGPTLRLH 340 SIVLKP Q + ML+ +++F MGFSWGG+ESL IPFDCS+YRT TKW+PGG T+RL Sbjct: 310 SIVLKPEFTQKGLAEMLDNMSIFAMGFSWGGYESLVIPFDCSEYRTVTKWNPGGLTIRLQ 369 Query: 341 IGLENLDDLKADLDRGFAAL 360 IGLE+++DLK DL +GF L Sbjct: 370 IGLEDMEDLKEDLAQGFIRL 389 >SMc02117 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases Sme Sinorhizobium meliloti Length = 395 Score = 349 bits (896), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 183/387 (47%), Positives = 234/387 (60%), Gaps = 40/387 (10%) Query: 13 QQAATRLVTAGRDTKAQKGFVNPPVFHGSTVLYPTAEDLHAHRAEFTYGRHGSPTTRALQ 72 Q TRL G + GFVNPPV H STVL+P A + ++TYG G+PTT AL Sbjct: 11 QGINTRLAHTGNNPSDFHGFVNPPVVHASTVLFPNARTMETRAQKYTYGTRGTPTTDALC 70 Query: 73 DVLMALEGPQCAGVGLAPSGLAAISTTLLAVLKAGEHLLVCDNAYRPTRNFCDNMLKRYG 132 + + LEG AG L PSGLAA++ LA L +G+H+L+ D+ Y PTR+FCD ML R G Sbjct: 71 EAVNELEG--AAGTILVPSGLAAVTVPFLAYLSSGDHVLIVDSVYFPTRHFCDTMLSRLG 128 Query: 133 IETSYFDPLVDAGIETLFKPNTRAVLIEAPGSQTFEMPDVRAISAVAHARGALMIDDNTW 192 + Y+DP + AGIE L +PNTR V EAPGS TFEM D+ AI+A AH G ++ DNTW Sbjct: 129 VTVEYYDPTIGAGIENLIRPNTRLVHTEAPGSNTFEMQDIPAIAAAAHRHGCIVTMDNTW 188 Query: 193 ATPLYHRSLEQGVDISMQAATKYIGGHSDIMFGTIAANAKAWPLIQEAIRLLGVCAGPDD 252 ATP+Y R L+ GVD+S+ AATKY GHSD++ GT++ANA WP + EA+ LGV PDD Sbjct: 189 ATPVYFRPLDHGVDVSIHAATKYPSGHSDVLLGTVSANAAHWPALSEAMVTLGVSVSPDD 248 Query: 253 VYLALRX----------------------------------ALDTDPGHAIWKRDFTGAS 278 Y LR AL + PGH +WKRDF GAS Sbjct: 249 SYQILRGLRTMGVRLVRHQASALAIAEWLEGRDEVARVLHPALPSFPGHELWKRDFGGAS 308 Query: 279 GLFSIVLKPVPQ---TAVDAMLNALTLFGMGFSWGGFESLAIPFDCSDYRTATKWSPGGP 335 G+FS VLK P+ A L+AL+LFG+G+SWGGFESLA+ + SD R K GP Sbjct: 309 GIFSFVLKAEPEDGKAKAHAFLDALSLFGLGYSWGGFESLAVHVNLSD-RKVAKAPSEGP 367 Query: 336 TLRLHIGLENLDDLKADLDRGFAALKA 362 +RL IGLE++ D++ D++ G AA A Sbjct: 368 VIRLQIGLEDVPDIRRDIEAGLAAANA 394 >mll8145 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases Mlo Mesorhizobium loti Length = 381 Score = 344 bits (883), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 184/380 (48%), Positives = 231/380 (60%), Gaps = 37/380 (9%) Query: 17 TRLVTAGRDTKAQKGFVNPPVFHGSTVLYPTAEDLHAHRAEFTYGRHGSPTTRALQDVLM 76 TRL +G + GFVNPPV H STVLY A + ++TYG G+PTT AL + Sbjct: 5 TRLAHSGNNPHDYFGFVNPPVVHASTVLYRNAAAMAGRSQKYTYGTRGTPTTDALAQAID 64 Query: 77 ALEGPQCAGVGLAPSGLAAISTTLLAVLKAGEHLLVCDNAYRPTRNFCDNMLKRYGIETS 136 ALEG AG PSGLAA++ LLA + AG+HLL+ D+ Y PTRNF D +LKR G+E Sbjct: 65 ALEG--SAGTIAVPSGLAAVTIPLLAFVSAGDHLLIVDSVYHPTRNFADTILKRLGVEVE 122 Query: 137 YFDPLVDAGIETLFKPNTRAVLIEAPGSQTFEMPDVRAISAVAHARGALMIDDNTWATPL 196 Y+DP + AGI L KPNT+ V E+P S TFE+ D+ AI+ VAH GA+++ DNTWATPL Sbjct: 123 YYDPHIGAGIAALIKPNTKVVFTESPASNTFEVQDIPAIAKVAHTAGAIVMMDNTWATPL 182 Query: 197 YHRSLEQGVDISMQAATKYIGGHSDIMFGTIAANAKAWPLIQEAIRLLGVCAGPDDVYLA 256 Y R L+ GVDIS+ AATKY GHSD++ GT++AN W + E+ LG CAGPDDVY Sbjct: 183 YFRPLDHGVDISIHAATKYPAGHSDVLLGTVSANESHWEQLYESFCTLGCCAGPDDVYQV 242 Query: 257 LRX----------------------------------ALDTDPGHAIWKRDFTGASGLFS 282 LR AL + P H +WKRDF G+SG+FS Sbjct: 243 LRGLRTMGVRLEHHQRSALAIASWLEGQKGVARVLHPALPSHPDHDLWKRDFCGSSGIFS 302 Query: 283 IVLKPVPQTAVDAMLNALTLFGMGFSWGGFESLAIPFDCSDYRTATKWSPGGPTLRLHIG 342 IVL Q A L+AL +FG+G+SWGG+ESLA+P D R K GP +RL IG Sbjct: 303 IVLAGGGQKEQHAFLDALRIFGLGYSWGGYESLAVPVWLGD-RVVAKGPYEGPLIRLQIG 361 Query: 343 LENLDDLKADLDRGFAALKA 362 LE++DDLKAD+ G AA A Sbjct: 362 LEDVDDLKADILGGLAAATA 381 >AGc2902 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 395 Score = 337 bits (864), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 182/381 (47%), Positives = 231/381 (60%), Gaps = 42/381 (11%) Query: 17 TRLVTAGRDTKAQKGFVNPPVFHGSTVLYPTAEDLHAHRAEFTYGRHGSPTTRALQDVLM 76 TRL G D GFVNPP+ GSTVL+P AE L ++TYG HG+PTT AL +++ Sbjct: 15 TRLTHGGNDPADCFGFVNPPIVRGSTVLFPDAETLSTEDQKYTYGTHGTPTTDALCNLVN 74 Query: 77 ALEGPQCAGVGLAPSGLAAISTTLLAVLKAGEHLLVCDNAYRPTRNFCDNMLKRYGIETS 136 LEG G L PSGLAAI+ LA L AG+H L+ D+ Y PTR FC+ MLK+ G+E Sbjct: 75 ELEG--SFGTILVPSGLAAITVPFLAYLGAGDHALIVDSVYFPTRRFCNTMLKKLGVEVE 132 Query: 137 YFDPLVDAGIETLFKPNTRAVLIEAPGSQTFEMPDVRAISAVAHARGALMIDDNTWATPL 196 Y+DP + AGIE L +PNT+ V +EAPGS TFE+ DVR I+ +AH ++ DNTWATPL Sbjct: 133 YYDPAIGAGIEALIRPNTKLVHLEAPGSNTFEIQDVRLITDIAHRHDCVVTMDNTWATPL 192 Query: 197 YHRSLEQGVDISMQAATKYIGGHSDIMFGTIAANAKAWPLIQEAIRLLGVCAGPDDVYLA 256 Y + L+ GVD+S+ AATKY GHSD++ G ++AN K W + +A LG+C PDD Y Sbjct: 193 YFKPLDFGVDVSIHAATKYPSGHSDVLMGFVSANEKYWKALYQANTNLGICVTPDDAYQI 252 Query: 257 LRX----------------------------------ALDTDPGHAIWKRDFTGASGLFS 282 LR AL + GH +WKRDF GASG+FS Sbjct: 253 LRGMRTMGIRLEHHQKSALDIAQWLEGRDDVVRVLHPALPSFAGHELWKRDFKGASGVFS 312 Query: 283 IVLK----PVPQTAVDAMLNALTLFGMGFSWGGFESLAIPFDCSDYRTATKWSPGGPTLR 338 VLK QTA A L+ALT FG+G+SWGG+ESLA+ D RT K GP +R Sbjct: 313 FVLKAEEGKYKQTA-SAFLDALTFFGLGYSWGGYESLAVSVSLVD-RTIAKGPSEGPVIR 370 Query: 339 LHIGLENLDDLKADLDRGFAA 359 L IGLE++ DLK DL+ GF+A Sbjct: 371 LQIGLEDVADLKKDLEAGFSA 391 >BMEI1213 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases Bme Brucella melitensis Length = 442 Score = 334 bits (857), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 176/378 (46%), Positives = 230/378 (60%), Gaps = 37/378 (9%) Query: 17 TRLVTAGRDTKAQKGFVNPPVFHGSTVLYPTAEDLHAHRAEFTYGRHGSPTTRALQDVLM 76 TRL G GFVNPPV STVL+P AE + ++ ++TYG G+PT+ AL + Sbjct: 68 TRLAHDGYCPGDYHGFVNPPVVRASTVLFPDAETMASNGQKYTYGTRGTPTSEALCKAID 127 Query: 77 ALEGPQCAGVGLAPSGLAAISTTLLAVLKAGEHLLVCDNAYRPTRNFCDNMLKRYGIETS 136 ALEG AG PSGLAAI+ LL L G+H L+ D+ Y PTR+F + +LKR G++ Sbjct: 128 ALEG--SAGTVCVPSGLAAITVPLLGFLSPGDHALLVDSIYYPTRHFANTILKRMGVDVE 185 Query: 137 YFDPLVDAGIETLFKPNTRAVLIEAPGSQTFEMPDVRAISAVAHARGALMIDDNTWATPL 196 Y+DP + A I L +PNT+ V E+P S TFE+ D+ AI+ AH A+++ DNTWATPL Sbjct: 186 YYDPEIGADIAKLMRPNTKVVFTESPASNTFEIQDIPAIAEAAHKGNAIVMMDNTWATPL 245 Query: 197 YHRSLEQGVDISMQAATKYIGGHSDIMFGTIAANAKAWPLIQEAIRLLGVCAGPDDVYLA 256 Y R+L+ GVDIS+ AATKY GHSDI+FGTI+ N K WP + E +G+CAGPDD Y Sbjct: 246 YFRALDFGVDISIHAATKYPSGHSDILFGTISTNEKCWPQLLETHGTMGLCAGPDDTYQI 305 Query: 257 LRX----------------------------------ALDTDPGHAIWKRDFTGASGLFS 282 LR AL++ PGH IWKRDF+G+SG+FS Sbjct: 306 LRRLRTMGIRLEHHRKSALEIARWLENHPMVERVLHPALESHPGHEIWKRDFSGSSGIFS 365 Query: 283 IVLKPVPQTAVDAMLNALTLFGMGFSWGGFESLAIPFDCSDYRTATKWSPGGPTLRLHIG 342 VL A LNAL +FG+G+SWGG++SLA+ D RT +K G +RL IG Sbjct: 366 FVLAKGEHAQASAFLNALEIFGLGYSWGGYQSLALEVKLGD-RTVSKNDYAGAVIRLQIG 424 Query: 343 LENLDDLKADLDRGFAAL 360 LE++ DL ADL+RGFAA+ Sbjct: 425 LEDVPDLIADLERGFAAI 442