BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0119.0015.p (1042 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1116 0.0 PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1066 0.0 YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1065 0.0 XF2385 [V] COG0841 Cation/multidrug efflux pump Xfa Xylella fast... 1038 0.0 RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1032 0.0 >RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1041 Score = 1116 bits (2887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 571/1033 (55%), Positives = 757/1033 (73%), Gaps = 5/1033 (0%) Query: 1 MSVSEPFIRRPIATSLLGIALMIGGALGYWALPVSALPQVDFPTVQVTTQLPGASPDVVA 60 M+ S FI RP+AT+LL +A+++ G + Y LP+SALP+VD+PT+QVTT PGASPDV+ Sbjct: 1 MNPSRIFILRPVATTLLMVAILLSGLVAYRMLPLSALPEVDYPTIQVTTLYPGASPDVMT 60 Query: 61 SLITAPLERQLGQIPSLSSMNSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGILP 120 S ITAPLERQ GQ+P L M S SS G S I+LQFDL+ +D A Q+VQAAINAA +LP Sbjct: 61 SSITAPLERQFGQMPGLKQMTSASSGGASVITLQFDLSLSLDIAEQEVQAAINAAGNLLP 120 Query: 121 KTLPYPPVYAKVNPADAPVMTLALTSETISLRAMSDLADTILGQRLSQISGVGRVSILGG 180 LP PP+Y+KVNPADAP++TLA+TS T+ L + D+ DT + Q+LSQ+ G+G VSI GG Sbjct: 121 TDLPMPPIYSKVNPADAPILTLAITSRTLPLPKLEDIVDTRVAQKLSQLPGIGLVSISGG 180 Query: 181 LKPAVRVQADLARLAAYGIAMEDLRNAIAGANVSGPKGSLDGAQQSYTIAANDQIAAADA 240 +PAVR+QA+ LAA G++++D+R AI ANV+G KGS DG ++ TI ANDQ+ +A Sbjct: 181 QRPAVRIQANTQALAALGLSIDDIRTAIGNANVNGAKGSFDGPMRASTIDANDQLRSAAE 240 Query: 241 YRPIIIAYRNGSPVTIGDVAQIVDGLENDRTGGWYQGTPAVIIDIQRQPGANVIDVVKQI 300 Y +I+AY+NG+P+ + DVAQI+DG EN + W TPA+I+++QRQPGANVIDVV + Sbjct: 241 YGTMIVAYKNGAPIRLTDVAQIIDGAENSKLAAWANTTPAIILNVQRQPGANVIDVVNRA 300 Query: 301 RGEIPRLQRAVPAGVKLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATL 360 + +P+L+ +PA + + +++DRT TIRASV DVQF L+L+V LV +V+ LFLR++ AT+ Sbjct: 301 KALLPQLKDTLPANIDVAVLTDRTTTIRASVADVQFELLLAVALVVMVIFLFLRNIPATI 360 Query: 361 IAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMEGGETV 420 I VA+PLSL+ +FG+MY AGFS++NL+LMALTI TGFVVDDAIVMIENI R++E G+ Sbjct: 361 IPAVAVPLSLVGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMIENIARYIEDGDPP 420 Query: 421 MEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAIVSLT 480 MEA+LKGA +IGFT+ISLT SLIAV IPLLFMS +VGR+FREFA+TL ++++ SA+VSLT Sbjct: 421 MEAALKGARQIGFTIISLTFSLIAVLIPLLFMSDVVGRLFREFAITLAVSILISAVVSLT 480 Query: 481 LTPMMCSRLLKNIHEEMAVPGLAAVSRFIDRMVEFYHRTLLWVLRRQRATLLVTFATIAL 540 LTPMMC+RLL++I E A +F D ++ Y R L WVL RQR TLLV T+AL Sbjct: 481 LTPMMCARLLRHIPEPEQTRFYHAAGQFFDNVIAQYGRMLQWVLDRQRTTLLVAIGTLAL 540 Query: 541 TLIMYVLAPKGFLPLQDTSSITAVTEAGPDVSFAEMQRRQSAVSNIIKADPDVVGVVSVI 600 T ++YV PKGF P+QDT I +++A +SF M RQ ++ +I DP V + S I Sbjct: 541 TGLLYVYVPKGFFPVQDTGVIQGISDATQSISFPAMAERQQKLAEVILKDPAVESLSSFI 600 Query: 601 GSGSVNPTTNVGRLVMTLKPLDERREGVVKVIERLKQKVAAVPGMTVYFQPVQDVQISTQ 660 G N T N GR+++ LKP D R ++I+RL+ ++A V G++++ QPVQD+ I + Sbjct: 601 GVDGTNTTLNSGRMLINLKPKDARDADATEIIQRLQPELAKVGGISLFMQPVQDLTIEDR 660 Query: 661 SSRSQYQYTLTATDAAEVSQWAQKLVAEMRRDPIFRDVSSEAQEGGLRAALDVNRQRAGQ 720 SR+QYQ+T+ D +S+W +LV +++ RDV+S+ Q+ GLRA + ++R +A Sbjct: 661 VSRTQYQFTVEDPDPNNLSKWVPRLVERLQQTGELRDVASDLQDNGLRAYVQIDRDKAAV 720 Query: 721 LGVSLQGVTDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILDKLYLPGANGAQ 780 GV+ V L A+ QR ISTI+ Q+NQYRVVLEA P Q+ P L L + G Q Sbjct: 721 YGVTTAAVDSALYSAYGQRLISTIFTQSNQYRVVLEAAPQLQKGPQSLYDLRVASTGGQQ 780 Query: 781 VPLSAVATLVRTTAPLAISHQAQFPSVSLSFNLAPGEALGDAVAAVKAIESRIGMPGSIV 840 VPL A AT+V L ++HQ QFPS ++SFNLA G +LG AV A+ A E IG+P S+ Sbjct: 781 VPLGAFATVVEQPGSLVVNHQGQFPSATISFNLARGASLGAAVDAINAAEQAIGLPASMQ 840 Query: 841 GIYSGDAAEFARSLAGQPWLILAAIITIYIVLGVLYESYIHPITILSTLPSAGVGAILAL 900 + G A F SL+ + WLILAAIIT+YIVLGVLYES IHP+TILSTLPSAGVGA+L+L Sbjct: 841 TSFQGAALAFQSSLSNELWLILAAIITMYIVLGVLYESTIHPVTILSTLPSAGVGALLSL 900 Query: 901 MLCGQDLSVIGLIGIILLIGIVKKNAIMMIDFALEAERHQGMSSYDAIVQACLLRFRPIM 960 ++ G+D+ +I +IGIILLIGIVKKNAIMMIDFALEAER QGM+ DAI QACLLRFRPI+ Sbjct: 901 LVSGKDMGIIAIIGIILLIGIVKKNAIMMIDFALEAEREQGMAPRDAIYQACLLRFRPIL 960 Query: 961 MTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRLNRRI 1020 MTT+AAL GALPL + +G G+ELR PLGI+++GGLL+SQ+LTL+TTPVIYLA D L R+ Sbjct: 961 MTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLAFDSLGHRL 1020 Query: 1021 -----ERAVRKRG 1028 RA R+ G Sbjct: 1021 RDWRERRAARRTG 1033 >PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1043 Score = 1066 bits (2757), Expect = 0.0, Method: Compositional matrix adjust. Identities = 563/1028 (54%), Positives = 758/1028 (73%) Query: 1 MSVSEPFIRRPIATSLLGIALMIGGALGYWALPVSALPQVDFPTVQVTTQLPGASPDVVA 60 M+ S PFI RP+AT+LL +A+++ G + Y LP+SALP+VD+PT+QV T PGASP+++ Sbjct: 1 MNPSRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMT 60 Query: 61 SLITAPLERQLGQIPSLSSMNSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGILP 120 S ITAPLE QLGQIP L+ M+S+SS G S I+LQF L ++D A Q+VQAAINAA +LP Sbjct: 61 SSITAPLENQLGQIPGLNEMSSSSSGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLP 120 Query: 121 KTLPYPPVYAKVNPADAPVMTLALTSETISLRAMSDLADTILGQRLSQISGVGRVSILGG 180 LP PV++KVNPADAP++TLA+ S+ + L + DL DT L Q++SQISGVG VSI GG Sbjct: 121 NDLPNQPVFSKVNPADAPILTLAVMSDGMPLPQIQDLVDTRLAQKISQISGVGLVSISGG 180 Query: 181 LKPAVRVQADLARLAAYGIAMEDLRNAIAGANVSGPKGSLDGAQQSYTIAANDQIAAADA 240 +PAVRV+A+ LAA G+++EDLR+ + N++GPKGS DG ++ T+ ANDQ+ +ADA Sbjct: 181 QRPAVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRASTLDANDQLRSADA 240 Query: 241 YRPIIIAYRNGSPVTIGDVAQIVDGLENDRTGGWYQGTPAVIIDIQRQPGANVIDVVKQI 300 YR +IIAY+NGSP+ I DVA + D EN R W PAV+++IQRQPGANVI+VV +I Sbjct: 241 YRDLIIAYKNGSPLRIRDVASVEDDAENVRLAAWANNLPAVVLNIQRQPGANVIEVVDRI 300 Query: 301 RGEIPRLQRAVPAGVKLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATL 360 + +P+LQ +P + + +++DRT TIRASV+DVQF L L+V LV +V LFLR++ ATL Sbjct: 301 KALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFLFLRNVYATL 360 Query: 361 IAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMEGGETV 420 I A+PLSLI +FG+MY +GFS++NL+LMALTI TGFVVDDAIVM+ENI R++E G++ Sbjct: 361 IPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIARYLEQGDSP 420 Query: 421 MEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAIVSLT 480 +EA+LKG+ +IGFT+ISLT SLIAV IPLLFM + GR+FREFA+TL +A++ S VSLT Sbjct: 421 LEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAILISGFVSLT 480 Query: 481 LTPMMCSRLLKNIHEEMAVPGLAAVSRFIDRMVEFYHRTLLWVLRRQRATLLVTFATIAL 540 LTPM+ ++LL++I E+ A R ID ++ Y + L VLR Q TLLV AT+AL Sbjct: 481 LTPMLSAKLLRHIDEDQQGRFARAAGRVIDGLIAQYAKALRVVLRHQPLTLLVAIATLAL 540 Query: 541 TLIMYVLAPKGFLPLQDTSSITAVTEAGPDVSFAEMQRRQSAVSNIIKADPDVVGVVSVI 600 T ++Y+ PKGF P+QDT I V EA +SF M RQ A++ ++ DP V + S I Sbjct: 541 TALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLKDPAVASLSSYI 600 Query: 601 GSGSVNPTTNVGRLVMTLKPLDERREGVVKVIERLKQKVAAVPGMTVYFQPVQDVQISTQ 660 G NPT N GRL++ LKP ER +VI+RL+ ++ +PG+ +Y QPVQD+ I + Sbjct: 601 GVDGSNPTLNTGRLLINLKPHSERDVTASEVIQRLQPELDHLPGIKLYMQPVQDLTIEDR 660 Query: 661 SSRSQYQYTLTATDAAEVSQWAQKLVAEMRRDPIFRDVSSEAQEGGLRAALDVNRQRAGQ 720 +R+QYQ+TL D +++W KLVA ++ P DV+S+ Q+ GL+A L+++R A + Sbjct: 661 VARTQYQFTLQDADPDVLAEWVPKLVARLQELPQLADVASDWQDKGLQAYLNIDRDTASR 720 Query: 721 LGVSLQGVTDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILDKLYLPGANGAQ 780 LGV L + L +AF QR ISTI+ QA QYRVVLE P +Q P L++LY+P ++G Q Sbjct: 721 LGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQFQLGPQALEQLYVPSSDGTQ 780 Query: 781 VPLSAVATLVRTTAPLAISHQAQFPSVSLSFNLAPGEALGDAVAAVKAIESRIGMPGSIV 840 V LS++A + LAI+H AQFPS +LSFNLA G +LG+AV A++ +E+ + +P S+ Sbjct: 781 VRLSSLAKVEERHTLLAINHIAQFPSATLSFNLAKGYSLGEAVEAIRGVEASLELPLSMQ 840 Query: 841 GIYSGDAAEFARSLAGQPWLILAAIITIYIVLGVLYESYIHPITILSTLPSAGVGAILAL 900 G + G A F SL+ LILA+++T+YIVLG+LYES+IHP+TILSTLPSAGVGA+LAL Sbjct: 841 GSFRGAALAFEASLSNTLLLILASVVTMYIVLGILYESFIHPVTILSTLPSAGVGALLAL 900 Query: 901 MLCGQDLSVIGLIGIILLIGIVKKNAIMMIDFALEAERHQGMSSYDAIVQACLLRFRPIM 960 ML GQ++ ++ +IGIILLIGIVKKNAIMMIDFAL+AER++G ++AI QACLLRFRPI+ Sbjct: 901 MLAGQEIGIVAIIGIILLIGIVKKNAIMMIDFALDAERNEGKPPHEAIYQACLLRFRPIL 960 Query: 961 MTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRLNRRI 1020 MTT+AAL GALPL + G GAELR PLGI+++GGLLLSQ+LTL+TTPVIYL DRL RR Sbjct: 961 MTTMAALLGALPLMLAGGAGAELRQPLGITMVGGLLLSQVLTLFTTPVIYLYFDRLARRW 1020 Query: 1021 ERAVRKRG 1028 ++RG Sbjct: 1021 AAWRKQRG 1028 >YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1052 Score = 1065 bits (2753), Expect = 0.0, Method: Compositional matrix adjust. Identities = 557/1028 (54%), Positives = 736/1028 (71%), Gaps = 8/1028 (0%) Query: 4 SEPFIRRPIATSLLGIALMIGGALGYWALPVSALPQVDFPTVQVTTQLPGASPDVVASLI 63 S FI RP+AT+L IA+++ G +GY ALPVSALP+VD+PT+QV T PGASPDVV S I Sbjct: 13 SRLFILRPVATTLFMIAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVVTSSI 72 Query: 64 TAPLERQLGQIPSLSSMNSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGILPKTL 123 TAPLERQ GQ+ L M S SS G S I+LQF L +D A Q+VQAAINAA +LP L Sbjct: 73 TAPLERQFGQMSGLKQMASQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDL 132 Query: 124 PYPPVYAKVNPADAPVMTLALTSETISLRAMSDLADTILGQRLSQISGVGRVSILGGLKP 183 PYPP+Y KVNPAD P++TLA+T+ I + + D+ +T + Q++SQ++GVG V++ GG +P Sbjct: 133 PYPPIYNKVNPADPPILTLAVTATAIPMTQVEDMVETRIAQKISQVTGVGLVTLSGGQRP 192 Query: 184 AVRVQADLARLAAYGIAMEDLRNAIAGANVSGPKGSLDGAQQSYTIAANDQIAAADAYRP 243 AVRV+ + +AA G+ E +R AI+ ANV+ KGSLDG +S T++ANDQ+ +A+ YR Sbjct: 193 AVRVKLNAPAVAALGLDSETIRTAISNANVNSAKGSLDGPTRSVTLSANDQMKSAEEYRD 252 Query: 244 IIIAYRNGSPVTIGDVAQIVDGLENDRTGGWYQGTPAVIIDIQRQPGANVIDVVKQIRGE 303 +IIAY+NG+P+ + DVA I G EN++ W A++++IQRQPG NVI IR Sbjct: 253 LIIAYQNGAPIRLQDVATIEQGAENNKLAAWANTQSAIVLNIQRQPGVNVIATADSIREM 312 Query: 304 IPRLQRAVPAGVKLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAG 363 +P L +++P V + +++DRT TIRASV DVQF L+L++ LV +V+ LFLR+ AT+I Sbjct: 313 LPELIKSLPKSVDVKVLTDRTSTIRASVNDVQFELLLAIALVVMVIYLFLRNAAATIIPS 372 Query: 364 VALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMEGGETVMEA 423 +A+PLSL+ +F MYF GFS++NL+LMALTI TGFVVDDAIV+IENI R++E GE ++A Sbjct: 373 IAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLDA 432 Query: 424 SLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAIVSLTLTP 483 +LKGA EIGFT+ISLT SLIAV IPLLFM +VGR+FREFA+TL +A++ SA+VSLTLTP Sbjct: 433 ALKGAGEIGFTIISLTFSLIAVLIPLLFMEDIVGRLFREFAVTLAVAILISAVVSLTLTP 492 Query: 484 MMCSRLL--KNIHEEMAVPGLAAVSRFIDRMVEFYHRTLLWVLRRQRATLLVTFATIALT 541 MMC+R+L +++ ++ + A +F D ++ Y L VL TL V F+T+ LT Sbjct: 493 MMCARMLSYESLRKQNRLS--RASEKFFDWVIAHYAVALKKVLNHPWLTLSVAFSTLVLT 550 Query: 542 LIMYVLAPKGFLPLQDTSSITAVTEAGPDVSFAEMQRRQSAVSNIIKADPDVVGVVSVIG 601 +I+Y+L PKGF PLQD I EA VSF+ M RQ V+ II DP V + S +G Sbjct: 551 VILYLLIPKGFFPLQDNGLIQGTLEAPQSVSFSNMAERQQQVAAIILKDPAVESLTSFVG 610 Query: 602 SGSVNPTTNVGRLVMTLKPLDERREGVVKVIERLKQKVAAVPGMTVYFQPVQDVQISTQS 661 N T N GRL + LKPL ER + + ++I RL++ V+ VPG+ +Y QPVQD+ I TQ Sbjct: 611 VDGTNATLNNGRLQINLKPLSERDDRIPQIITRLQESVSGVPGIKLYLQPVQDLTIDTQL 670 Query: 662 SRSQYQYTLTATDAAEVSQWAQKLVAEMRRDPIFRDVSSEAQEGGLRAALDVNRQRAGQL 721 SR+QYQ+TL AT E+S W KLV E+++ F+DV+S+ Q+ GL A ++V+R A +L Sbjct: 671 SRTQYQFTLQATSLEELSTWVPKLVNELQQKAPFQDVTSDWQDQGLVAFVNVDRDSASRL 730 Query: 722 GVSLQGVTDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSI--LDKLYLPGANGA 779 G+++ + + L +AF QR ISTIY Q+NQYRVVLE Q P + + + L G +G Sbjct: 731 GITMAAIDNALYNAFGQRLISTIYTQSNQYRVVLEH--DVQATPGLAAFNDIRLTGIDGK 788 Query: 780 QVPLSAVATLVRTTAPLAISHQAQFPSVSLSFNLAPGEALGDAVAAVKAIESRIGMPGSI 839 VPLS++AT+ PL+I+H QFPS ++SFNLA G +LG+AVAAV E I +P I Sbjct: 789 GVPLSSIATIEERFGPLSINHLNQFPSATVSFNLAQGYSLGEAVAAVTLAEKEIQLPADI 848 Query: 840 VGIYSGDAAEFARSLAGQPWLILAAIITIYIVLGVLYESYIHPITILSTLPSAGVGAILA 899 + G F +L WLI+AAI+ +YIVLGVLYES+IHPITILSTLP+AGVGA+LA Sbjct: 849 TTRFQGSTLAFQAALGSTLWLIIAAIVAMYIVLGVLYESFIHPITILSTLPTAGVGALLA 908 Query: 900 LMLCGQDLSVIGLIGIILLIGIVKKNAIMMIDFALEAERHQGMSSYDAIVQACLLRFRPI 959 LML G +L VI +IGIILLIGIVKKNAIMMIDFAL AER QGM+ YDAI QACLLRFRPI Sbjct: 909 LMLTGNELDVIAIIGIILLIGIVKKNAIMMIDFALAAERDQGMTPYDAIYQACLLRFRPI 968 Query: 960 MMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRLNRR 1019 +MTTLAALFGALPL + +G GAELR PLG+ ++GGL++SQ+LTL+TTPVIYL D+L R Sbjct: 969 LMTTLAALFGALPLMLSTGVGAELRQPLGVCMVGGLIVSQVLTLFTTPVIYLLFDKLARN 1028 Query: 1020 IERAVRKR 1027 R R Sbjct: 1029 TRGKNRHR 1036 >XF2385 [V] COG0841 Cation/multidrug efflux pump Xfa Xylella fastidiosa 9a5c Length = 1077 Score = 1038 bits (2683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/1066 (52%), Positives = 738/1066 (69%), Gaps = 44/1066 (4%) Query: 7 FIRRPIATSLLGIALMIGGALGYWALPVSALPQVDFPTVQVTTQLPGASPDVVASLITAP 66 FIRRPIATSLL +++ G LGY LP+SALP+VD P++ VTTQ PGA+ +A+L+T P Sbjct: 13 FIRRPIATSLLMFGVLLLGILGYKKLPMSALPEVDAPSLVVTTQYPGANAKTMAALVTTP 72 Query: 67 LERQLGQIPSLSSMNSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGILPKTLPYP 126 LE QLGQI L M+S SS G+S I+LQF ++++D A QDVQAAI+ A ILP LP+ Sbjct: 73 LEHQLGQISGLDIMSSDSSAGLSTITLQFSTHKNLDIAAQDVQAAIHQA--ILPSALPHQ 130 Query: 127 PVYAKVNPADAPVMTLALTSETISLRAMSDLADTILGQRLSQISGVGRVSILGGLKPAVR 186 P+Y +VNPADA ++TL LTS+T+ LR ++ AD IL QRLSQISGVG VSI G ++PAVR Sbjct: 131 PIYNRVNPADAAIITLKLTSDTLPLRELNTYADAILAQRLSQISGVGLVSIAGNVRPAVR 190 Query: 187 VQADLARLAAYGIAMEDLRNAIAGANVSGPKGSLDGAQQSYTIAANDQIAAADAYRPIII 246 +Q + A+L+ G+ ME LRN + ANV+ PKGSL+G QSY+I NDQ+ A YR II Sbjct: 191 IQVNPAQLSNMGLTMESLRNTLTQANVNAPKGSLNGKSQSYSIGTNDQLKDASQYRDTII 250 Query: 247 AYRNGSPVTIGDVAQIVDGLENDRTGGWYQGTPAVIIDIQRQPGANVIDVVKQIRGEIPR 306 Y+NG PV + +VA +VDG+END+ W PAV+++I+RQPGAN+I V+QIR +P+ Sbjct: 251 HYQNGHPVRLSEVADVVDGVENDQISAWANAKPAVLLEIRRQPGANIIQTVEQIRAILPQ 310 Query: 307 LQRAVPAGVKLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVAL 366 L+ +P V L + SDRT TIRASV +V+FTL+L++ LV V+ +FLR L ATLI VA+ Sbjct: 311 LRAVLPTDVHLDVFSDRTETIRASVHEVKFTLLLTIGLVVAVIFVFLRRLWATLIPSVAV 370 Query: 367 PLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMEGGETVMEASLK 426 PLSL +F +M F G SLDNLSLMAL + TGFVVDDAIVMIENIVR++E G++ EA+ Sbjct: 371 PLSLAGTFSVMAFNGMSLDNLSLMALVVATGFVVDDAIVMIENIVRYIEQGKSGREAAEI 430 Query: 427 GASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAIVSLTLTPMMC 486 GA +IGFT++SLT+SL+AVF+PLL M G+ GR+F EFA L+ AVV S +VSLTLTPMMC Sbjct: 431 GARQIGFTILSLTISLVAVFLPLLLMPGVTGRLFHEFAWVLSTAVVISMLVSLTLTPMMC 490 Query: 487 SRLLK-NIHEEMAVPGLAAVSRFIDRMVEFYHRTLLWVLRRQRATLLVTFATIALTLIMY 545 + LLK + E P + R V Y RTL WVL Q+ TL+V T+ALT+++Y Sbjct: 491 AYLLKPDTLPESDSPTPSTKITLWTRTVALYERTLDWVLMHQQLTLVVALVTVALTIVLY 550 Query: 546 VLAPKGFLPLQDTSSITAVTEAGPDVSFAEMQRRQSAVSNIIKADPDVVGVVSVIGSGSV 605 V PKG LP QDT I V +A D++F++M++R AV++ ++ DP V GV + IG+G++ Sbjct: 551 VTIPKGLLPEQDTGLIIGVVQADQDIAFSQMEQRTRAVADALRKDPAVTGVSAFIGAGTI 610 Query: 606 NPTTNVGRLVMTLKPLDERREGVVKVIERLKQKVAAVPGMTVYFQPVQDVQISTQSSRSQ 665 NPT N G+L + LKP ++ REG+ + RL++ A +PG+ +Y +PVQDV + T + ++ Sbjct: 611 NPTLNHGQLSIVLKPRNQ-REGLNTIRPRLQRAAAGIPGIVLYLKPVQDVTLDTHVAATE 669 Query: 666 YQYTLTATDAAEVSQWAQKLVAEMRRDPIFRDVSSEAQEGGLRAALDVNRQRAGQLGVSL 725 YQY+L+ DA E++ WA ++ MR+ P DV + + G + V+R +A LGV + Sbjct: 670 YQYSLSNVDATELATWATRMTEAMRQIPALTDVDNNLADQGRALQITVDRDKASLLGVPM 729 Query: 726 QGVTDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILDKL--------YLPGAN 777 Q + DTL DAF QRQISTI+ + NQYRVVLE P ++ ++ +L L G+N Sbjct: 730 QTINDTLYDAFGQRQISTIFTELNQYRVVLEVAPHFRTSTALTQQLGVASNGSGALTGSN 789 Query: 778 -----------------------------GAQVPLSAVATLVRTTAPLAISHQAQFPSVS 808 G +PLSA+A T AP ISHQ Q P+V+ Sbjct: 790 ATSFGQAVSSNSSTATGIGNRNTGMTVGTGRIIPLSALADAKVTNAPRVISHQQQLPAVT 849 Query: 809 LSFNLAPGEALGDAVAAVKAIESRIGMPGSIVGIYSGDAAEFARSLAGQPWLILAAIITI 868 +SFNLA G +L AV A++ +++ +P + + G A EF S + WL+LA+I+ I Sbjct: 850 ISFNLAQGYSLSHAVKAIEQARTQLQIPPQVRVQFIGKAVEFTSSQSDIVWLLLASIVVI 909 Query: 869 YIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLIGIVKKNAIM 928 YIVLGVLYESYIHP+TI+STLPSAGVGA+LALMLCG LSV ++GI+LLIGIVKKNAIM Sbjct: 910 YIVLGVLYESYIHPLTIISTLPSAGVGALLALMLCGLSLSVDSIVGIVLLIGIVKKNAIM 969 Query: 929 MIDFALEAERHQGMSSYDAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLG 988 MIDFA+EA R G S++DAI +ACLLRFRPI+MTT AAL GALPLA+ G GAELR PLG Sbjct: 970 MIDFAIEA-RSTGSSAHDAIRRACLLRFRPIIMTTAAALLGALPLALGDGIGAELRRPLG 1028 Query: 989 ISIIGGLLLSQLLTLYTTPVIYLALDRLNRRIE--RAVRKRGPSGP 1032 I+I+GGLLLSQL+TLYTTPVIYL +RL+ R+ RA R + P Sbjct: 1029 ITIVGGLLLSQLITLYTTPVIYLFFERLSERLRLWRAHRTSVQATP 1074 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1032 bits (2668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/1016 (53%), Positives = 715/1016 (70%), Gaps = 8/1016 (0%) Query: 1 MSVSEPFIRRPIATSLLGIALMIGGALGYWALPVSALPQVDFPTVQVTTQLPGASPDVVA 60 M++S FI RP+AT+LL I + + G + LPVS LPQVDFPT+ V LPGASP+ +A Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 SLITAPLERQLGQIPSLSSMNSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGILP 120 + + PLER LG+I ++ M S S+ G ++++LQFDL+RDIDGA +DVQAAINA+ +LP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 KTLPYPPVYAKVNPADAPVMTLALTSETISLRAMSDLADTILGQRLSQISGVGRVSILGG 180 LP P Y KVNPADAP+M L LTS+T S + D A TIL Q+LSQI+GVG+V+I G Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 LKPAVRVQADLARLAAYGIAMEDLRNAIAGANVSGPKGSLDGAQQSYTIAANDQIAAADA 240 PAVRV+ + L YGI+ E +R I N + PKG L+ + +T+ ANDQ A+ Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 YRPIIIAYRNGSPVTIGDVAQIVDGLENDRTGGWYQGTPAVIIDIQRQPGANVIDVVKQI 300 Y+P+IIAYRNG+PV + DVA++ D +++ R G G P+V++ I RQPGAN+ID V +I Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 301 RGEIPRLQRAVPAGVKLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATL 360 +P L+ +PA + L ++ DRT TIRAS+RDV+ TL+LS+ LV +VV LFLR+LRATL Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 361 IAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMEGGETV 420 I VA+P+SLI +FG+MY G+SLDNLSLMALT+ TGFVVDDAIV++EN+ RH+E G Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVLENVSRHIENGMRP 420 Query: 421 MEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAIVSLT 480 M+A+LKGA E+GFTV+S++ SLIAVFIPLL M G+VGR+FREFA+TL++A++ S +SLT Sbjct: 421 MQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTLSVAILVSLAISLT 480 Query: 481 LTPMMCSRLLKNIHEEMAVPGL--AAVSRFIDRMVEFYHRTLLWVLRRQRATLLVTFATI 538 TPMMC+RLLK EE PG F + +++ Y +L W LR TLL+ AT+ Sbjct: 481 TTPMMCARLLKPASEEE--PGWFHRKTEGFFNLLLDGYRHSLAWALRHSWLTLLILLATV 538 Query: 539 ALTLIMYVLAPKGFLPLQDTSSITAVTEAGPDVSFAEMQRRQSAVSNIIKADPDVVGVVS 598 L +YV+ PKGF P QD + +A +SF M+ + +I++ DP V VV Sbjct: 539 CLNGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIVQQDPAVENVVG 598 Query: 599 VIGSGSVNPTTNVGRLVMTLKPLDERREGVVKVIERLKQKVAAVPGMTVYFQPVQDVQIS 658 G +N G++ + LKPL ER+ +VI RL+ K+A PG ++ Q VQD++I Sbjct: 599 FTGGSQINS----GQMFIQLKPLAERKLSADQVINRLRGKLAREPGANLFLQAVQDIRIG 654 Query: 659 TQSSRSQYQYTLTATDAAEVSQWAQKLVAEMRRDPIFRDVSSEAQEGGLRAALDVNRQRA 718 + S +QYQYTL A + E+ W K+ + + DV+++AQ+ G + AL +R +A Sbjct: 655 GRPSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTALVFDRDKA 714 Query: 719 GQLGVSLQGVTDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILDKLYLPGANG 778 LG++ + + + LN+AF QRQ+STIY NQYRVV+EA P Y ++P L +YL A+G Sbjct: 715 MALGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRDIYLITASG 774 Query: 779 AQVPLSAVATLVRTTAPLAISHQAQFPSVSLSFNLAPGEALGDAVAAVKAIESRIGMPGS 838 AQVPLS + T PLA++HQ QF + +LSFNLAPG +L A ++ +RIG+P + Sbjct: 775 AQVPLSTFSHYGPTNTPLAVNHQGQFAASTLSFNLAPGASLSAATQQIQDAMNRIGVPTT 834 Query: 839 IVGIYSGDAAEFARSLAGQPWLILAAIITIYIVLGVLYESYIHPITILSTLPSAGVGAIL 898 + G + G A F SL+ QP LIL A+ITIYIVLGVLYESY+HPITILSTLPSAGVGA+L Sbjct: 835 VHGSFQGTARAFQDSLSSQPVLILFALITIYIVLGVLYESYVHPITILSTLPSAGVGALL 894 Query: 899 ALMLCGQDLSVIGLIGIILLIGIVKKNAIMMIDFALEAERHQGMSSYDAIVQACLLRFRP 958 AL++ D SVI LIG+ILLIGIVKKNAIMMIDFALEAER QGMS DAI AC+LRFRP Sbjct: 895 ALIVTDTDFSVIALIGVILLIGIVKKNAIMMIDFALEAERSQGMSPADAIFHACVLRFRP 954 Query: 959 IMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALD 1014 I+MTT+AAL GALPLA+ G GAELR PLGISI+GGLL+SQ+LTLYTTPV+YLALD Sbjct: 955 ILMTTMAALLGALPLALGHGDGAELRQPLGISIVGGLLVSQILTLYTTPVVYLALD 1010