BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0118.0031.p (297 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yvbV [GER] COG0697 Permeases of the drug/metabolite transport... 107 4e-23 BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transport... 102 1e-21 ZyijE [GER] COG0697 Permeases of the drug/metabolite transporter... 74 6e-13 RSp0685 [GER] COG0697 Permeases of the drug/metabolite transport... 73 1e-12 yijE [GER] COG0697 Permeases of the drug/metabolite transporter ... 72 1e-12 >BS_yvbV [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 305 Score = 107 bits (266), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 88/273 (32%), Positives = 138/273 (50%), Gaps = 9/273 (3%) Query: 4 QKPSARPRLAPAGLMFLAITSVGWGFNWPSTKFLLSELPPLTLRGTTGVIGAVLLAVLAV 63 Q P R L LA + WG NWP +K L+ PPL G +IG +LL ++A+ Sbjct: 3 QLPKTRTAL------LLAFLVIMWGVNWPLSKAALAYSPPLLFAGIRTLIGGLLLVIVAL 56 Query: 64 IRAQSLHVEKRLWPRLVLYAALNVTGWMVLMGLALLWLPASEAALIAYTMPVWASLLAWP 123 R L + K WP ++ A LN+T + L + L +LPA + I + PV + +W Sbjct: 57 PRIHKLRL-KETWPIYLVSALLNITLFYGLQTIGLNYLPAGLFSAIVFFQPVLMGVFSWL 115 Query: 124 VLGERPTLLRTIALVMAFAGLAAIMGGSGISASKEKLPGIIMALGGAFGFALGTVLAKKY 183 LGE +++ I L++ FAG+A I +G + G+++ALG A +ALGTV KK Sbjct: 116 WLGESMFVMKVIGLILGFAGVAVI-SAAGFGGHISVI-GVLLALGSAVSWALGTVYMKKT 173 Query: 184 PLVMPPIPAAAWQIGLGCVPIAIVGLLIETTHLDRITTVGWWLLVYSTLIQFCVAYVAWF 243 + I A Q+ +G V + I G E+ + T L++ ++ + ++ +F Sbjct: 174 GSRVDSIWMVALQLTIGSVFLLISGFWTESFSAIQWTAPFITSLLFISVFVIALGWLVFF 233 Query: 244 AALARLPASVAAIGTMAVPVIGVVASAIALHEP 276 + AS A T +P+I +VAS+I LHEP Sbjct: 234 TLVGSGEASKVASYTFLIPLISIVASSIFLHEP 266 >BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 292 Score = 102 bits (253), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 131/270 (48%) Query: 27 WGFNWPSTKFLLSELPPLTLRGTTGVIGAVLLAVLAVIRAQSLHVEKRLWPRLVLYAALN 86 WG+ W + K + ++PPL G IGAV L ++ I+ + L ++K ++ + L Sbjct: 15 WGYTWVAMKVGIHDIPPLLFSGLRLFIGAVPLFLILFIQRKKLSIQKEHLKSYIIMSLLM 74 Query: 87 VTGWMVLMGLALLWLPASEAALIAYTMPVWASLLAWPVLGERPTLLRTIALVMAFAGLAA 146 G+M ++ + ++ + + +++ YTMP++ ++++ L E+ + +T+ LV GL Sbjct: 75 GLGYMGILTYGMQFVDSGKTSVLVYTMPIFVTVISHFSLNEKMNVYKTMGLVCGLFGLLF 134 Query: 147 IMGGSGISASKEKLPGIIMALGGAFGFALGTVLAKKYPLVMPPIPAAAWQIGLGCVPIAI 206 I G ++ + L G + L A + + V +K + I AW + +G V + + Sbjct: 135 IFGKEMLNIDQSALFGELCVLVAALSWGIANVFSKLQFKHIDIIHMNAWHLMMGAVMLLV 194 Query: 207 VGLLIETTHLDRITTVGWWLLVYSTLIQFCVAYVAWFAALARLPASVAAIGTMAVPVIGV 266 + E T W L+++ L+ +V WF L ++ AS A++ M VPV+ + Sbjct: 195 FSFIFEAVPSAEWTYQAVWSLLFNGLLSTGFTFVVWFWVLNQIQASKASMALMFVPVLAL 254 Query: 267 VASAIALHEPLGPSQIVALLFTLAGVALAT 296 + LHE + + I+ L G+ + T Sbjct: 255 FFGWLQLHEQITINIILGALLICCGIFMNT 284 >ZyijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 312 Score = 73.6 bits (179), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 76/298 (25%), Positives = 140/298 (46%), Gaps = 16/298 (5%) Query: 7 SARPRLAPAGLMFLAITSVGWGFNWPSTKFLLSELPPLTLRGTTGVIGAVLLAVLAVIRA 66 SA + P + L + ++ W ++W K + S + + GA++L ++ ++R Sbjct: 13 SAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRG 72 Query: 67 QSLHVEKRLWPRLVLY----AALNVTGWMVLMGLALLWLPASEAALIAYTMPVWASLLAW 122 + + P Y A L G + L AL+ A + A+++YTMP W + A Sbjct: 73 RGMR------PTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAILSYTMPFWVVIFAA 126 Query: 123 PVLGERPTLLRTIALVMAFAGLAAIMGGSGISASKEKLPGIIMALGGAFGFALGTVLAKK 182 LGER + A+++A GL ++ + S K ++A+ + ++AK+ Sbjct: 127 VFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMK--SAMLAILSGVSWGASAIVAKR 184 Query: 183 YPLVMPPIPA---AAWQIGLGCVPIAIVGLLIETTHLDRITTVGWWLLVYSTLIQFCVAY 239 P + +WQ+ + +++V LL+ +D TV +W L YS ++ +A+ Sbjct: 185 LYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTV-FWALAYSAILATALAW 243 Query: 240 VAWFAALARLPASVAAIGTMAVPVIGVVASAIALHEPLGPSQIVALLFTLAGVALATR 297 W L LPAS+A++ T+AVPV GV+ S L E G + ++ + +AL +R Sbjct: 244 SLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEXSGIVLIVLALALVSR 301 >RSp0685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 300 Score = 72.8 bits (177), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 78/290 (26%), Positives = 135/290 (46%), Gaps = 17/290 (5%) Query: 16 GLMFLAITSVGWGFNWPSTKFLLSELPPLTLRGTTGVIGAVLLAVLAVIRAQS-LHVEKR 74 G + L++ + G ++K + LPP + L L ++R Q + R Sbjct: 7 GYLLLSLAMMTVGSTVIASKLIAGNLPPFPATALRFAVALPFLFALVLLRGQRWPRLSGR 66 Query: 75 LWPRLVLYAALNVTGWMVLMGLALLWLPASEAALIAYTMPVWASLLAWPVLGERPTLLRT 134 W LVL A G+ L+ L LPA++A ++ T+P ++L + VLGERP L Sbjct: 67 AWGLLVLQAGAGSVGYTTLLISGLAHLPAADAGVVIGTLPAVSALFSVIVLGERPKLRLM 126 Query: 135 IALVMAFAGLAAIM-GGSGISASKEKLPGIIMALGGAFGFALGTVLAKKYPLVMPPIPAA 193 +++++A G+ A+ GSG L G++ LG + +L K+ P+ +PP+ A Sbjct: 127 VSVLLATIGVMAVAWTGSG----SAPLTGVLFILGAVVCESAFILLNKRMPVPLPPLLQA 182 Query: 194 AWQIGLG---CVPIAIVGLLIETTHLDRITTVGWWLLVYSTLIQFCVAYVAWFAALARLP 250 LG +P A++ I V W+ LV + ++ W+A AR+ Sbjct: 183 TAMTALGLLVSLPFAVLEFPATVPSTAAIAAVVWYALVPT-----VGGFLLWYAGAARVS 237 Query: 251 ASVAAIGTMAVPVIGVVASAIALHEPLGPSQ---IVALLFTLAGVALATR 297 S AA T P+ V +A+ L+E +G +Q +VA++ + + L+ R Sbjct: 238 GSEAATFTAVAPLTAVALAALFLNERIGATQAFGVVAVILAILTLTLSVR 287 >yijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 312 Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 76/298 (25%), Positives = 140/298 (46%), Gaps = 16/298 (5%) Query: 7 SARPRLAPAGLMFLAITSVGWGFNWPSTKFLLSELPPLTLRGTTGVIGAVLLAVLAVIRA 66 SA + P + L + ++ W ++W K + S + + GA++L ++ ++R Sbjct: 13 SAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRG 72 Query: 67 QSLHVEKRLWPRLVLY----AALNVTGWMVLMGLALLWLPASEAALIAYTMPVWASLLAW 122 + + P Y A L G + L AL+ A + A+++YTMP W + A Sbjct: 73 RGMR------PTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAILSYTMPFWVVIFAA 126 Query: 123 PVLGERPTLLRTIALVMAFAGLAAIMGGSGISASKEKLPGIIMALGGAFGFALGTVLAKK 182 LGER + A+++A GL ++ + S K ++A+ + ++AK+ Sbjct: 127 LFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMK--SAMLAILSGVSWGASAIVAKR 184 Query: 183 YPLVMPPIPA---AAWQIGLGCVPIAIVGLLIETTHLDRITTVGWWLLVYSTLIQFCVAY 239 P + +WQ+ + +++V LL+ +D TV +W L YS ++ +A+ Sbjct: 185 LYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTV-FWALAYSAILATALAW 243 Query: 240 VAWFAALARLPASVAAIGTMAVPVIGVVASAIALHEPLGPSQIVALLFTLAGVALATR 297 W L LPAS+A++ T+AVPV GV+ S L E G + ++ + +AL +R Sbjct: 244 SLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGSGIVLIVLALALVSR 301