BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0117.0067.p (275 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc4015 [E] COG0345 Pyrroline-5-carboxylate reductase Atu Agroba... 253 4e-67 SMc02677 [E] COG0345 Pyrroline-5-carboxylate reductase Sme Sinor... 243 4e-64 mll6498 [E] COG0345 Pyrroline-5-carboxylate reductase Mlo Mesorh... 199 7e-51 BMEII0509 [E] COG0345 Pyrroline-5-carboxylate reductase Bme Bruc... 188 1e-47 PA0393 [E] COG0345 Pyrroline-5-carboxylate reductase Pae Pseudom... 164 2e-40 >AGc4015 [E] COG0345 Pyrroline-5-carboxylate reductase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 274 Score = 253 bits (646), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 147/272 (54%), Positives = 182/272 (66%), Gaps = 2/272 (0%) Query: 5 SALKNSTGTIALAGAGKMGGAMLTGWLAQGLAPARVAVIDPHLSPEI-SALAAKGVRLNP 63 S + ++G + L GAG MGGAML+GWL +G+ ++V VIDP S + + +A G + Sbjct: 2 SMVYKASGPLVLVGAGNMGGAMLSGWLKKGVPGSKVIVIDPRPSDAMRTTIAEAGATHSE 61 Query: 64 QAKDLGTVDTLVVAVKPQSFRDAGAALKSFVGPSTLVVSIMAGTTMSALEEVVGG-AVVR 122 + L VAVKPQ +LK +GP T+VVSI AGTT++ G A VR Sbjct: 62 SVPEGVKAGILFVAVKPQMMDAILPSLKPLLGPETVVVSIAAGTTIATFVSHFGAVAAVR 121 Query: 123 AMPNTPAAIGRGITVVVQSKSVTAAQRAMTDALLKATGLVEWVDDESLMDAVTAVSGSGP 182 AMPNTPA +GRG+T + VTA + + D LLK +G VEWV+ ES +DAVTAVSGSGP Sbjct: 122 AMPNTPAMVGRGVTGAYANDLVTAELKTVVDGLLKVSGPVEWVEAESDIDAVTAVSGSGP 181 Query: 183 AYVFLLAEELARAGVAAGLPEQLATTLARATVAGSGELLHRSDLPSATLRQNVTSPGGTT 242 AYVF L E +A AG AGLP +A LAR TVAG+GELLH+S +A LRQNVTSPGGTT Sbjct: 182 AYVFYLVECMAEAGRKAGLPADVAMRLARETVAGAGELLHQSPEEAARLRQNVTSPGGTT 241 Query: 243 AAALEVLMANDGMQPLMTRAIAAATRRSKELA 274 AAAL VLMA DGMQPL RA+AAA R++ELA Sbjct: 242 AAALSVLMAEDGMQPLFDRAVAAAKTRAEELA 273 >SMc02677 [E] COG0345 Pyrroline-5-carboxylate reductase Sme Sinorhizobium meliloti Length = 272 Score = 243 bits (620), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 151/266 (56%), Positives = 180/266 (67%), Gaps = 2/266 (0%) Query: 11 TGTIALAGAGKMGGAMLTGWLAQGLAPARVAVIDPHLSPEISALAAK-GVRLNPQAKDLG 69 +G I L GAG MGGAML GWL G+ + V VIDP SP ++ L A GV+ A G Sbjct: 6 SGPIVLVGAGNMGGAMLAGWLKSGVRGSDVLVIDPGPSPAMAKLLADSGVQHATSAPAGG 65 Query: 70 TVDTLVVAVKPQSFRDAGAALKSFVGPSTLVVSIMAGTTMSALEEVVG-GAVVRAMPNTP 128 + +AVKPQ LK VGP T++VS+ AG T+ +E +G A VRAMPNTP Sbjct: 66 KAGAIFLAVKPQVMETVLPPLKGLVGPQTVIVSVAAGKTLGFIERHLGEAATVRAMPNTP 125 Query: 129 AAIGRGITVVVQSKSVTAAQRAMTDALLKATGLVEWVDDESLMDAVTAVSGSGPAYVFLL 188 A IGRG+T + V+ AQRA+ LLK +G VEWV E+ +DAVTAVSGSGPAYVF L Sbjct: 126 AMIGRGVTGAFANARVSEAQRALVHDLLKVSGPVEWVGSEADIDAVTAVSGSGPAYVFYL 185 Query: 189 AEELARAGVAAGLPEQLATTLARATVAGSGELLHRSDLPSATLRQNVTSPGGTTAAALEV 248 E +A AG AGL LA LAR TVAG+GELLH+S +A LRQNVTSPGGTTAAAL V Sbjct: 186 VECMAEAGRKAGLEADLAMRLARETVAGAGELLHQSPDDAARLRQNVTSPGGTTAAALAV 245 Query: 249 LMANDGMQPLMTRAIAAATRRSKELA 274 LMA+DGMQPL RAIAAA +R++ELA Sbjct: 246 LMADDGMQPLFDRAIAAARKRAEELA 271 >mll6498 [E] COG0345 Pyrroline-5-carboxylate reductase Mlo Mesorhizobium loti Length = 271 Score = 199 bits (505), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 130/272 (47%), Positives = 160/272 (58%), Gaps = 9/272 (3%) Query: 11 TGTIALAGAGKMGGAMLTGWLAQG-LAPARVAVIDPHLSPEISALAAK-GVRLNPQAKDL 68 T + LAG G MG AML+GWL G LAP+ V VI+P+ E+ AA G + A ++ Sbjct: 2 TNRLVLAGCGNMGYAMLSGWLKSGKLAPSAVFVIEPN--AELRQRAATLGCATSADAGEI 59 Query: 69 ---GTVDTLVVAVKPQSFRDAGAALKSFVGPSTLVVSIMAGTTMSALEEVVGG--AVVRA 123 D +V+AVKPQ RD AA K F T VSI AGT ++ E+++G VVR Sbjct: 60 PADAVPDLVVIAVKPQVIRDVTAAYKRFGDGRTTFVSIAAGTPVATFEDILGNRAPVVRC 119 Query: 124 MPNTPAAIGRGITVVVQSKSVTAAQRAMTDALLKATGLVEWVDDESLMDAVTAVSGSGPA 183 MPNTPA+IG+G+ VV + V+ + LL A+G V +DDE LMDAVTAVSGSGPA Sbjct: 120 MPNTPASIGKGMMVVFSNPLVSDDTKRFVADLLSASGEVATIDDEGLMDAVTAVSGSGPA 179 Query: 184 YVFLLAEELARAGVAAGLPEQLATTLARATVAGSGELLHRSDLPSATLRQNVTSPGGTTA 243 Y+F E L A AGLP A LA TV G+ L S LRQ VTSP GTTA Sbjct: 180 YIFHFIEALTVAAEKAGLPSATARLLAMQTVYGAASLAAESQEEPGVLRQQVTSPNGTTA 239 Query: 244 AALEVLMANDGMQPLMTRAIAAATRRSKELAK 275 AAL VLM D + L+T+A+ AA RS EL K Sbjct: 240 AALAVLMGEDRLTNLLTQAVEAARLRSIELGK 271 >BMEII0509 [E] COG0345 Pyrroline-5-carboxylate reductase Bme Brucella melitensis Length = 300 Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 125/274 (45%), Positives = 161/274 (58%), Gaps = 10/274 (3%) Query: 9 NSTGTIALAGAGKMGGAMLTGWLAQGLAPA-RVAVIDP-HLSPEISALAAKGVRLNPQAK 66 N + L G G MG AML GWL G+ A V V++P E +ALA V + A Sbjct: 29 NMQDKVVLVGCGNMGFAMLRGWLDSGILKAGDVHVVEPAEALRERAALAH--VHVYADAA 86 Query: 67 DLG---TVDTLVVAVKPQSFRDAGAALKSFVGPSTLVVSIMAGTTMSALEEVVGG--AVV 121 DL ++VAVKPQ + A K F P++ VS+ AG ++ E +G AV+ Sbjct: 87 DLPADLQPRMVLVAVKPQMMANVLPAYKRF-APASTFVSVAAGIPVALFESHLGKDVAVI 145 Query: 122 RAMPNTPAAIGRGITVVVQSKSVTAAQRAMTDALLKATGLVEWVDDESLMDAVTAVSGSG 181 R MPNTPAAIG+G+ V ++ +V+ A A +LLK +G V VD+E LMDAVTAVSGSG Sbjct: 146 RCMPNTPAAIGKGMLVTFKNANVSDANEAFVTSLLKTSGKVASVDEEGLMDAVTAVSGSG 205 Query: 182 PAYVFLLAEELARAGVAAGLPEQLATTLARATVAGSGELLHRSDLPSATLRQNVTSPGGT 241 PAY+F E L AGV GLP + A LA TV G+G L S + LR+ VTSP GT Sbjct: 206 PAYIFHFIEALTDAGVNLGLPRETAALLAMQTVMGAGALADASTDSPSKLREQVTSPNGT 265 Query: 242 TAAALEVLMANDGMQPLMTRAIAAATRRSKELAK 275 TAAAL+VLM D ++ L+ A+ AA +RS EL K Sbjct: 266 TAAALDVLMGGDRLKELVAEAVKAAHKRSVELGK 299 >PA0393 [E] COG0345 Pyrroline-5-carboxylate reductase Pae Pseudomonas aeruginosa Length = 273 Score = 164 bits (414), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 108/270 (40%), Positives = 158/270 (58%), Gaps = 6/270 (2%) Query: 10 STGTIALAGAGKMGGAMLTGWLAQGLAPARVAVIDP--HLSPEISALAAKGVRLNPQAKD 67 ST IA GAG M +++ G AQG+ A++ DP +I+ A V + A+ Sbjct: 2 STPRIAFIGAGNMAASLIGGLRAQGVPAAQIRASDPGAEQRAKIAGEFAIDV-VESNAEA 60 Query: 68 LGTVDTLVVAVKPQSFRDAGAALKSFVGPSTLVVSIMAGTTMSALEEVVGGA--VVRAMP 125 + D +V++VKPQ+ + AL + P L+VSI AG ++LE +G VVR MP Sbjct: 61 VADADVVVLSVKPQAMKAVCQALAPALKPEQLIVSIAAGIPCASLEAWLGQPRPVVRCMP 120 Query: 126 NTPAAIGRGITVVVQSKSVTAAQRAMTDALLKATGLVEWVDDESLMDAVTAVSGSGPAYV 185 NTPA + +G + + + V+AAQ LL A G+ W+DDE+ +DAVTAVSGSGPAY Sbjct: 121 NTPALLRQGASGLYANAQVSAAQCEQAGQLLSAVGIALWLDDEAQIDAVTAVSGSGPAYF 180 Query: 186 FLLAEELARAGVAAGLPEQLATTLARATVAGSGELLHRSDLPSATLRQNVTSPGGTTAAA 245 FLL + + AG GL + A+ L T G+ ++ S++ A LR+ VTSP GTT AA Sbjct: 181 FLLMQAMTDAGEKLGLSRETASRLTLQTALGAAQMALSSEVEPAELRRRVTSPNGTTEAA 240 Query: 246 LEVLMANDGMQPLMTRAIAAATRRSKELAK 275 ++ AN G + L+ +A+ AA++RS ELA+ Sbjct: 241 IKSFQAN-GFEALVEQALNAASQRSAELAE 269