BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0117.0016.p (290 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3358 [GER] COG0697 Permeases of the drug/metabolite transporte... 225 7e-59 RSc1607 [GER] COG0697 Permeases of the drug/metabolite transport... 199 5e-51 mlr3480 [GER] COG0697 Permeases of the drug/metabolite transport... 189 7e-48 SMb20885 [GER] COG0697 Permeases of the drug/metabolite transpor... 175 8e-44 AGc4246 [GER] COG0697 Permeases of the drug/metabolite transport... 166 5e-41 >PA3358 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 225 bits (574), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 143/281 (50%), Positives = 185/281 (65%), Gaps = 4/281 (1%) Query: 14 PAIFVVLWSTGFIGTKYVINNAEPLTYLAIRMAFVVVVMAVIAAIAPPNWPDRTGIF-HS 72 P +FV+LWSTGF+G K+ + AEP T+LAIR+ ++A A ++ WP + H Sbjct: 12 PLLFVLLWSTGFLGAKFGLPYAEPFTFLAIRLLLAAALLAAFALLSGAPWPGSARLAGHV 71 Query: 73 AVAGILVHGFYLGGTAIAIAHSVPAGLSALIPGLQPILTSTIANRWLGERVTPLQWGGLV 132 AVAG+LVHG YLGG +AI H + AGL++L+ GLQP+ T+ +A WLGE+V+ QW GL Sbjct: 72 AVAGLLVHGLYLGGVFLAIEHGMSAGLTSLLVGLQPLATAALAGIWLGEQVSRRQWLGLA 131 Query: 133 LGFAGVVLILHNRPMTGEAGWGWLASGVSLISITLGTLYQRRYCNRIDWRAGNLVQYIAV 192 LG AGV L++ R G G W A V+L +IT GTLYQ+R+C +D R G +VQY+A Sbjct: 132 LGLAGVALVVLGRIHGGADGLAWAAVLVALAAITCGTLYQKRFCGGMDLRTGGVVQYLAS 191 Query: 193 TIFFGIGAFVFETNVVHWTGEFVLALAWLVFALSIGSIGLLYWLIRHHAATSVASLFYLV 252 G+ A +FE+ V W+ FVL L WLV LS G++GLLY LIRH AA+ VASLFYLV Sbjct: 192 GALLGLAALLFESREVQWSTPFVLTLGWLVLGLSFGAVGLLYTLIRHGAASKVASLFYLV 251 Query: 253 PAVTALMAYILFDERLDHVAIAGMAACAAAVLLVN---RRA 290 P VTAL +++LFDERL AI GM V LVN RRA Sbjct: 252 PPVTALASWLLFDERLAPAAIGGMLLVMLGVALVNWPGRRA 292 >RSc1607 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 307 Score = 199 bits (507), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 129/287 (44%), Positives = 166/287 (57%), Gaps = 12/287 (4%) Query: 14 PAIFVVLWSTGFIGTKYVINNAEPLTYLAIRMAFVVVVMAVIAAIAPPNWPDRTG----- 68 P +FV++WSTGF+ K+ + AEP+T+L +R V+V + + +A P R G Sbjct: 22 PWLFVLIWSTGFVVAKFGMPYAEPITFLFLRFVGVLVCLLPLVWVARVPLPRRAGADADA 81 Query: 69 -----IFHSAVAGILVHGFYLGGTAIAIAHSVPAGLSALIPGLQPILTSTIANRWLGERV 123 I H AVAG+L+ YLGG AI +PAG+SALI G+QPILT+ + GERV Sbjct: 82 VDWRTIGHLAVAGVLMQWGYLGGVWEAIKLGMPAGMSALIVGMQPILTALYVSM-RGERV 140 Query: 124 TPLQWGGLVLGFAGVVLILHNRPMTGEAGWGWLASGV-SLISITLGTLYQRRYCNRIDWR 182 +P QW GL+ G AGV L++ N+ L V +L+SIT GTLYQ+R+C D R Sbjct: 141 SPRQWLGLLFGIAGVGLVVANKLHLAGVNVTTLGFCVGALLSITAGTLYQKRFCPVFDLR 200 Query: 183 AGNLVQYIAVTIFFGIGAFVFETNVVHWTGEFVLALAWLVFALSIGSIGLLYWLIRHHAA 242 G +Q+ A + F FET V WTG + AL W V ALSIG+I LL+ LIR AA Sbjct: 201 MGACIQFGASALLCLPFMFAFETRAVQWTGPMIGALVWSVLALSIGAISLLFMLIRQGAA 260 Query: 243 TSVASLFYLVPAVTALMAYILFDERLDHVAIAGMAACAAAVLLVNRR 289 T V SL YL P TA MA+ LF ER +A GM A V LV RR Sbjct: 261 TKVTSLLYLTPPTTAAMAWALFGERFPPLAALGMVIAACGVALVIRR 307 >mlr3480 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 303 Score = 189 bits (480), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 118/288 (40%), Positives = 169/288 (58%), Gaps = 7/288 (2%) Query: 7 ETAARLAPAIFVVLWSTGFIGTKYVINNAEPLTYLAIRMAFVVVVMAVIAAIAPPNWPDR 66 ++ R PA FVVLW+TGFIG +Y + AEP T+LA R +++AV+ + R Sbjct: 2 QSIKRFIPATFVVLWATGFIGARYAMPWAEPFTFLAARFVIAAILLAVLMPVLGSKRATR 61 Query: 67 TGIFHSAVAGILVHGFYLGGTAIAIAHSVPAGLSALIPGLQPILTSTIANRWLGERVTPL 126 H+ AG+L+HG YLG AI +PAG SALI GLQP++T+ +A ++LGE + P Sbjct: 62 KEALHATGAGVLMHGVYLGAVFWAIHRGMPAGFSALIVGLQPLITAVLAGKFLGEAILPR 121 Query: 127 QWGGLVLGFAGVVLILHNRPMTGEAGWG-----WLASGVSLISITLGTLYQRRYCNRIDW 181 W L LG + +++ P G G G AS VS++ ++ GT++Q+R+ + D Sbjct: 122 HW--LGLGIGLIGIVIVLWPKLGALGGGVTAATLTASLVSVLGMSAGTIWQKRFASGGDL 179 Query: 182 RAGNLVQYIAVTIFFGIGAFVFETNVVHWTGEFVLALAWLVFALSIGSIGLLYWLIRHHA 241 A + QY+ + A FET+ V GE + A+AWLV LS+G+I LL +IR Sbjct: 180 VAATMWQYVGGASLMILAALAFETHTVIINGELIFAMAWLVLVLSLGAIFLLMVMIRDGE 239 Query: 242 ATSVASLFYLVPAVTALMAYILFDERLDHVAIAGMAACAAAVLLVNRR 289 + VASLFYLVPAVTA++A+ LFDE+L+ + I GMA V L R Sbjct: 240 MSKVASLFYLVPAVTAIIAWALFDEQLNALQIVGMAITTFGVGLATAR 287 >SMb20885 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 306 Score = 175 bits (444), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 114/292 (39%), Positives = 162/292 (55%), Gaps = 15/292 (5%) Query: 10 ARLAPAIFVVLWSTGFIGTKYVINNAEPLTYLAIRMAFVVVVMAVIAAIAPPNWP-DRTG 68 ARLAPAIFV+LWSTG++ KY A+PL +LA+R +F +++ ++ WP T Sbjct: 3 ARLAPAIFVLLWSTGWVVAKYAAIFADPLIFLALRYSFAILLFIGFCLLSGARWPRSATA 62 Query: 69 IFHSAVAGILVHGFYLGGTAIAIAHSVPAGLSALIPGLQPILTSTIANRWLGERVTPLQW 128 I H+ V+GI +HG YLG AI VPA +S +I GLQP++T+ +A +GE++ Q Sbjct: 63 IGHAVVSGIFLHGLYLGAVWWAIGQGVPAAISGIIAGLQPLMTAAVAPWLIGEKLAGQQK 122 Query: 129 GGLVLGFAGVVLILHNRPMTGEAGWGWLASGVSLI----------SITLGTLYQRRYCNR 178 GL+LGF G+ L + + +T +A A+ + L+ ++T GTLYQ+RY Sbjct: 123 LGLILGFCGIALAVAPKMLTIDA----TATPIHLLPLAVNVLGMAAVTYGTLYQKRYLQT 178 Query: 179 IDWRAGNLVQYIAVTIFFGIGAFVFETNVVHWTGEFVLALAWLVFALSIGSIGLLYWLIR 238 D R+ +QY+ + A + E V W E V ALAW V LS+G+I LL +LIR Sbjct: 179 GDIRSIAALQYVGALLVTIPLALMLEDLRVTWNIELVAALAWSVLGLSMGAIALLLYLIR 238 Query: 239 HHAATSVASLFYLVPAVTALMAYILFDERLDHVAIAGMAACAAAVLLVNRRA 290 + ASL YLVP + A A + F E L I G V L NR+A Sbjct: 239 RGQVSRAASLIYLVPPLAAGEAALFFGEALTWPMIIGTVIAVTGVYLTNRKA 290 >AGc4246 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 354 Score = 166 bits (420), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 109/298 (36%), Positives = 165/298 (55%), Gaps = 13/298 (4%) Query: 2 NKSFEETAARLAPAIFVVLWSTGFIGTKYVINNAEPLTYLAIRMAFVVVVMAVIAAIAPP 61 ++ + RLAPAIFV LWSTG++ KY + PLT+L +R +++ I + Sbjct: 52 HRRCSMSLDRLAPAIFVFLWSTGWVTAKYAVYYTGPLTFLCLRYLLAGLLLWAICRFSGI 111 Query: 62 NWP-DRTGIFHSAVAGILVHGFYLGGTAIAIAHSVPAGLSALIPGLQPILTSTIANRWLG 120 +WP R + + ++G+ +HG YLG AI VPA + +I GLQP++T+ A +G Sbjct: 112 SWPKQRADVLRAILSGVFLHGIYLGMIWWAIGQGVPAAIGGIIAGLQPLMTAVAARFMIG 171 Query: 121 ERVTPLQWGGLVLGFAGVVLILHNRPM-TGEAG-----WGWLASGVSLISITLGTLYQRR 174 ER++PLQ GL+LGFAG+ + + + M TG G + + + ++S+T GTLYQ++ Sbjct: 172 ERISPLQRAGLLLGFAGIAIAVLPKVMATGALGMSVPLYAVAVNVLGMVSVTYGTLYQKK 231 Query: 175 YCNRIDWRAGNLVQYIA---VTIFFGIGAFVFETNVVHWTGEFVLALAWLVFALSIGSIG 231 Y + + A +QY+ VT+ F A + E V W+ L W V A+SIG++ Sbjct: 232 YVHGGNIMAVATLQYVGALLVTVPF---ALLLEDGHVDWSLGLAATLGWSVGAISIGAVA 288 Query: 232 LLYWLIRHHAATSVASLFYLVPAVTALMAYILFDERLDHVAIAGMAACAAAVLLVNRR 289 LL +LIR + ASL YLVP + A+ A +LF E L IAG V L NR+ Sbjct: 289 LLLYLIRRGQVSRAASLIYLVPPLAAVEAAVLFGETLTPAMIAGTVLAVTGVYLANRK 346