BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0116.0064.p         (173 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MT0156 [IQR] COG1028 Dehydrogenases with different specificities...    97   2e-20
Rv0148 [IQR] COG1028 Dehydrogenases with different specificities...    96   3e-20
PA3427 [IQR] COG1028 Dehydrogenases with different specificities...    96   5e-20
PA1023 [IQR] COG1028 Dehydrogenases with different specificities...    95   6e-20
CC2093 [IQR] COG1028 Dehydrogenases with different specificities...    92   4e-19

>MT0156 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) MtC Mycobacterium
           tuberculosis CDC1551
          Length = 293

 Score = 96.7 bits (239), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 55/118 (46%), Positives = 70/118 (59%), Gaps = 6/118 (5%)

Query: 1   MKVHLKGTFCCTQPVFKWMRDNGGGVIVNTSSTSGLIGNFGQTNYGAAKGGIWGLSNVLA 60
           +KVHL G +   +  +   R+   G +V  +STSGL GNFGQTNYGAAK G+ GL N LA
Sbjct: 127 LKVHLYGGYHVLRAAWPHFREQSYGRVVVATSTSGLFGNFGQTNYGAAKLGLVGLINTLA 186

Query: 61  IEGRKYNIRIWTLAPGALTRMTADL--PRYKENPGAALGPDGIAPAVLYMVSDLSGDQ 116
           +EG KYNI    LAP A TRMT D+  P   E     L P+ +AP V Y+ ++   D 
Sbjct: 187 LEGAKYNIHANALAPIAATRMTQDILPPEVLEK----LTPEFVAPVVAYLCTEECADN 240


>Rv0148 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Mtu Mycobacterium
           tuberculosis H37Rv
          Length = 286

 Score = 96.3 bits (238), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 55/118 (46%), Positives = 70/118 (59%), Gaps = 6/118 (5%)

Query: 1   MKVHLKGTFCCTQPVFKWMRDNGGGVIVNTSSTSGLIGNFGQTNYGAAKGGIWGLSNVLA 60
           +KVHL G +   +  +   R+   G +V  +STSGL GNFGQTNYGAAK G+ GL N LA
Sbjct: 120 LKVHLYGGYHVLRAAWPHFREQSYGRVVVATSTSGLFGNFGQTNYGAAKLGLVGLINTLA 179

Query: 61  IEGRKYNIRIWTLAPGALTRMTADL--PRYKENPGAALGPDGIAPAVLYMVSDLSGDQ 116
           +EG KYNI    LAP A TRMT D+  P   E     L P+ +AP V Y+ ++   D 
Sbjct: 180 LEGAKYNIHANALAPIAATRMTQDILPPEVLEK----LTPEFVAPVVAYLCTEECADN 233


>PA3427 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Pae Pseudomonas
           aeruginosa
          Length = 303

 Score = 95.5 bits (236), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 62/161 (38%), Positives = 94/161 (58%), Gaps = 9/161 (5%)

Query: 2   KVHLKGTFCCTQPVFKWMRDNGGGVIVNTSSTSGLIGNFGQTNYGAAKGGIWGLSNVLAI 61
           +VH++G +  T+  +  +R+   G +V TSSTSG+ GNFGQ+NYG AK G++GL+  LA+
Sbjct: 121 QVHVEGAYKVTRAAWPHLREQAYGRVVFTSSTSGIYGNFGQSNYGMAKLGLYGLTRTLAL 180

Query: 62  EGRKYNIRIWTLAPGALTRMTADL--PRYKENPGAALGPDGIAPAVLYMVSDLSGDQTGK 119
           EGRK NI +  +AP   TRMT  L  P+  E     L P+ ++P V+Y+ S    D +G 
Sbjct: 181 EGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQ----LKPELVSPLVVYLGSSACEDTSG- 235

Query: 120 VLGVSGPRGVREMRMMEMEGWK-PPFTGWKAEDIVTHAKEI 159
            L   G   + ++R     G+   P  G+ AED+  H ++I
Sbjct: 236 -LYEVGGGWIGKVRWERSLGFGFDPKAGFDAEDVAAHWQQI 275


>PA1023 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Pae Pseudomonas
           aeruginosa
          Length = 305

 Score = 95.1 bits (235), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 56/166 (33%), Positives = 85/166 (51%), Gaps = 17/166 (10%)

Query: 1   MKVHLKGTFCCTQPVFKWMRDNGGGVIVNTSSTSGLIGNFGQTNYGAAKGGIWGLSNVLA 60
           + VHL G+F  ++   +  R    G  V+ +STSGLIGNFGQ NY AAK GI  LS  +A
Sbjct: 122 INVHLNGSFFVSRAAAERFRTQQAGAFVHMTSTSGLIGNFGQANYSAAKLGIVALSKSIA 181

Query: 61  IEGRKYNIRIWTLAPGALTRMTADLP------RYKENPGAALGPDGIAPAVLYMVSDLSG 114
           ++ ++YN+R   +AP A +RMT  +P      + + +    + P+  AP  +Y+ SD + 
Sbjct: 182 LDMQRYNVRSNCIAPFAWSRMTDSIPAETPEQKARVDKLQRMTPEKNAPLAVYLASDAAR 241

Query: 115 DQTGKVLGVSGPRGVREMRMMEMEGWKPPFT-----GWKAEDIVTH 155
           + TG+V         R   +  M   +P  +     GW  E I  H
Sbjct: 242 EVTGQVF------AARHHELFLMSQSRPLRSVHSEHGWTPESIAEH 281


>CC2093 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Ccr Caulobacter
           vibrioides
          Length = 301

 Score = 92.4 bits (228), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 61/154 (39%), Positives = 87/154 (56%), Gaps = 9/154 (5%)

Query: 1   MKVHLKGTFCCTQPVFKWMRDNGGGVIVNTSSTSGLIGNFGQTNYGAAKGGIWGLSNVLA 60
           M+VH+ GTF   + V+  M+    G IV T+S+SG+ GNFGQ+NYGAAK  + GL N L 
Sbjct: 122 MQVHVFGTFKPIKAVWDIMKAQNYGRIVVTTSSSGMYGNFGQSNYGAAKMAVLGLMNTLK 181

Query: 61  IEGRKYNIRIWTLAPGALTRMTADL--PRYKENPGAALGPDGIAPAVLYMVSDLSGDQTG 118
           +EG K +++I  ++P A TRMT  L  P       A L P+ + P V+Y+ SD +   TG
Sbjct: 182 LEGAKNDVKINAISPVAATRMTEGLMPPEVL----AKLAPEYVTPGVVYLCSDEA--PTG 235

Query: 119 KVLGVSGPRGVREMRMMEMEGWKPPFTGWKAEDI 152
            +L  +G       R+ E EG      G  AE++
Sbjct: 236 AIL-TAGAGAFALSRIYETEGVYLGEGGLSAEEV 268