BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0116.0061.p (302 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc02511 [GER] COG0697 Permeases of the drug/metabolite transpor... 357 2e-98 AGc4240 [GER] COG0697 Permeases of the drug/metabolite transport... 344 1e-94 mlr5337 [GER] COG0697 Permeases of the drug/metabolite transport... 336 4e-92 AGc3767 [GER] COG0697 Permeases of the drug/metabolite transport... 177 3e-44 SMc01844 [GER] COG0697 Permeases of the drug/metabolite transpor... 124 3e-28 >SMc02511 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 301 Score = 357 bits (915), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 188/279 (67%), Positives = 230/279 (82%), Gaps = 1/279 (0%) Query: 24 WGGSYTFIKLGVATIPPITLIAARTAIAGLLLLAIMRMRGVTMPADGATWVRFIFQACLN 83 WG SYTFIK+GV TIPP+TLIAART IAG +LLA++ RG+T+P DGA W RF+FQACLN Sbjct: 20 WGASYTFIKIGVETIPPVTLIAARTLIAGTVLLALIAWRGLTLPRDGAMWRRFLFQACLN 79 Query: 84 SVIPWTLIAWGERFVDAGLATILNSASPIFTFLFTAAITRHEAASLRKLFGVISGMAGIC 143 SV+P+TLIAW ER DAG+A ILNS +PIF FL TA ITRHE + RK GV++G+AGI Sbjct: 80 SVVPFTLIAWSERTTDAGVAAILNSTTPIFAFLLTALITRHEPVTARKFLGVLAGIAGIG 139 Query: 144 LIVGVDAFRDLGQGILAEVAIVAATICYACAAIFSRGFKGLDPMAPAAGSLIAGAAILVP 203 LI+G++AFR +G ++ ++A+V AT+CYA AAIF +GF+GLDPM PA GSL+AGAA+L+P Sbjct: 140 LIIGLEAFRGIGDQLIPQLAVVLATVCYAGAAIFGKGFRGLDPMMPACGSLLAGAALLIP 199 Query: 204 LSLVVERPWTLSPSTTSLAALLALAMFSTAIAFAIYFRLIQTLGSVGTTAQAYLRVPIGV 263 SLVV+RPWTL PS SL ALL L++FSTA+AF IYFRLI TLGSVG TAQAY+RVPIGV Sbjct: 200 ASLVVDRPWTLDPSPESLIALLCLSVFSTALAFVIYFRLIHTLGSVGATAQAYVRVPIGV 259 Query: 264 ALSVMVLGERLSPTAWIGLACVVIGVAAMTIPAR-RIAT 301 A+ V+ LGE LS TAW+GL CV+ GVAAMT+P R R+AT Sbjct: 260 AIGVVFLGETLSTTAWLGLGCVIAGVAAMTMPTRPRVAT 298 >AGc4240 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 302 Score = 344 bits (883), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 180/292 (61%), Positives = 231/292 (79%) Query: 7 QPSMGFELALLLALATMWGGSYTFIKLGVATIPPITLIAARTAIAGLLLLAIMRMRGVTM 66 Q ++ EL L L+T+W SYTFIK+GV TIPP+T IAART IAGLLLL ++R+RG+ + Sbjct: 4 QNTIARELLFLALLSTLWAASYTFIKIGVETIPPLTFIAARTLIAGLLLLVVIRLRGLRL 63 Query: 67 PADGATWVRFIFQACLNSVIPWTLIAWGERFVDAGLATILNSASPIFTFLFTAAITRHEA 126 P D ATW F QAC+NSV+P+TLIAW E+ +DAGLA ILN+ +PIFTFL TA + RHE Sbjct: 64 PRDPATWRLFFVQACINSVLPFTLIAWAEQSIDAGLAVILNATTPIFTFLLTALVIRHET 123 Query: 127 ASLRKLFGVISGMAGICLIVGVDAFRDLGQGILAEVAIVAATICYACAAIFSRGFKGLDP 186 S RKLFG I+GM G+CLI+GV+A G+ I +++A++ A YACAAIFS+ FKGLDP Sbjct: 124 VSGRKLFGTIAGMTGVCLIIGVEALGGAGEAIWSQLAVLTAAFSYACAAIFSKNFKGLDP 183 Query: 187 MAPAAGSLIAGAAILVPLSLVVERPWTLSPSTTSLAALLALAMFSTAIAFAIYFRLIQTL 246 + PAAGSLI GA +L+P+SL+V+RPWTLSPS SL AL+ L++FSTA+AF IYFRL+QTL Sbjct: 184 VMPAAGSLICGAVLLLPVSLIVDRPWTLSPSAASLTALVCLSVFSTALAFMIYFRLMQTL 243 Query: 247 GSVGTTAQAYLRVPIGVALSVMVLGERLSPTAWIGLACVVIGVAAMTIPARR 298 GSVGTT+QAYLRVP+GVA+ ++ LGE + W+GL CV+ GV AMT+P+RR Sbjct: 244 GSVGTTSQAYLRVPVGVAIGMVFLGEVPTSAMWVGLVCVIAGVLAMTLPSRR 295 >mlr5337 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 255 Score = 336 bits (861), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 174/249 (69%), Positives = 202/249 (81%) Query: 50 IAGLLLLAIMRMRGVTMPADGATWVRFIFQACLNSVIPWTLIAWGERFVDAGLATILNSA 109 IAG +L AI+R RG+ MP D ATW RF FQACLNSVIP+TLIA ER VDAGLATILN+ Sbjct: 2 IAGGILFAIIRWRGLAMPGDTATWRRFAFQACLNSVIPFTLIAAAERSVDAGLATILNAT 61 Query: 110 SPIFTFLFTAAITRHEAASLRKLFGVISGMAGICLIVGVDAFRDLGQGILAEVAIVAATI 169 SPIFTFL TA ITRHE + RKL GV +G+AGICLIVG +A +G + A+VAIVAATI Sbjct: 62 SPIFTFLLTALITRHEPVTARKLIGVGAGIAGICLIVGTEALGGIGHELWAQVAIVAATI 121 Query: 170 CYACAAIFSRGFKGLDPMAPAAGSLIAGAAILVPLSLVVERPWTLSPSTTSLAALLALAM 229 CYA AAIF RGFKGLDPM PAAGS++ GA +LVPLSLV ++PW L+PST S+ ALL L++ Sbjct: 122 CYAGAAIFGRGFKGLDPMLPAAGSMLCGAVMLVPLSLVADQPWALTPSTASILALLGLSV 181 Query: 230 FSTAIAFAIYFRLIQTLGSVGTTAQAYLRVPIGVALSVMVLGERLSPTAWIGLACVVIGV 289 FSTA+AF IYFRLI TLGSVGTT+QAYLRVPIGV + + LGE L PTAW+G+A VV GV Sbjct: 182 FSTALAFVIYFRLIHTLGSVGTTSQAYLRVPIGVGIGAIFLGESLGPTAWLGMAFVVAGV 241 Query: 290 AAMTIPARR 298 AAMTIP R+ Sbjct: 242 AAMTIPVRK 250 >AGc3767 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 329 Score = 177 bits (448), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 100/284 (35%), Positives = 175/284 (61%), Gaps = 6/284 (2%) Query: 13 ELALLLALATMWGGSYTFIKLGVATIPPITLIAARTAIAGLLLLAIMRMRGVTMPADGAT 72 E A+L+AL+ +WGGS+ FI + V +PP+T++ R ++A + LL + R+ G+ +P + A Sbjct: 31 EWAMLIALSLLWGGSFFFIGVAVKELPPVTIVTLRVSLAAVALLVVCRIMGLRLPREWAV 90 Query: 73 WVRFIFQACLNSVIPWTLIAWGERFVDAGLATILNSASPIFTFLFTAAITRHEAASLRKL 132 W F LN++IP+ LI WG+ + +GLA+ILN+ +P+FT + +T E + KL Sbjct: 91 WRAFFGMGLLNNIIPFCLIVWGQTQIASGLASILNATTPLFTVIVAHFLTADEKMTGNKL 150 Query: 133 FGVISGMAGICLIVGVDAFRDLGQGILAEVAIVAATICYACAAIFSRGFK--GLDPMAPA 190 GV+ G G+ ++G AF G+ ++AI+ A I Y+ A IF R FK G+ P+ A Sbjct: 151 AGVLIGFVGVATMIGPAAFGG-SSGLWGQIAILGAAISYSFAGIFGRRFKAMGVPPLMTA 209 Query: 191 AGSLIAGAAILVPLSLVVERPWTLS-PSTTSLAALLALAMFSTAIAFAIYFRLIQTLGSV 249 G + + +L+P +L++++PWTL+ P + AL+ +A+ STA+A+ I+FR++ + G+ Sbjct: 210 TGQISSSTLMLIPAALLIDKPWTLAMPGLGTWGALIGIALLSTALAYLIFFRILASAGAT 269 Query: 250 GTTAQAYLRVPIG-VALSVMVLGERLSPTAWIGLACVVIGVAAM 292 +L +P+ + L ++LGE+L + G+A + G+AA+ Sbjct: 270 NLALVTFL-IPVSAILLGSLILGEQLEIKHFAGMAMIAAGLAAI 312 >SMc01844 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 314 Score = 124 bits (310), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 90/272 (33%), Positives = 142/272 (52%), Gaps = 8/272 (2%) Query: 26 GSYTFIKLGVATIPPITLIAARTAIAGLLLLAIMRMRGVTMPADGATWVRFIFQACLNSV 85 GS+ F ++ VA +PP TL+ R +A L L +R R PA W F+ +N+ Sbjct: 29 GSFFFARVAVAHVPPFTLVLLRLGLAALALHLYLRGRHGIYPALAGRWREFLLMGLINNA 88 Query: 86 IPWTLIAWGERFVDAGLATILNSASPIFTFLFTAAITRHEAASLRKLFGVISGMAGICLI 145 IP I G+ + AGLA ILN+ +P++T L T E S K G + G+AG ++ Sbjct: 89 IPHAFIFLGQTHIGAGLAAILNATTPVWTVLIANVATEDEKLSTAKFSGCLLGLAGTVVL 148 Query: 146 VGVDAFRDLGQGILAEVAI------VAATICYACAAIFSRGFKGLDPMAPAAGSLIAGAA 199 +G A L G +V + V A + Y +A + + F+ L P AAG L A Sbjct: 149 IGPSALAGL-FGTAGDVPLWALVLPVLAAVSYGFSATYGKRFRDLAPPVTAAGQLTASTL 207 Query: 200 ILVPLSLVVERPWTLS-PSTTSLAALLALAMFSTAIAFAIYFRLIQTLGSVGTTAQAYLR 258 I++P++++V+ PWT+ P T++ A+L LA+ STA A+ ++FR++ G+ T+ L Sbjct: 208 IMLPVAVLVDMPWTMPMPPLTTVLAILGLALVSTAYAYILFFRIMAEAGATNTSLVTLLV 267 Query: 259 VPIGVALSVMVLGERLSPTAWIGLACVVIGVA 290 P + L + LGE L T G+ + G+A Sbjct: 268 PPSAILLGYLFLGEMLQATDVGGMLLIAAGLA 299