BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0115.0161.p         (363 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AGpA360 [R] COG2334 Putative homoserine kinase type II (protein ...   284   3e-76
mlr6716 [R] COG2334 Putative homoserine kinase type II (protein ...   196   8e-50
BMEII0132 [R] COG2334 Putative homoserine kinase type II (protei...    97   5e-20
BS_yerI [R] COG2334 Putative homoserine kinase type II (protein ...    76   1e-13

>AGpA360 [R] COG2334 Putative homoserine kinase type II (protein kinase
           fold) Atu Agrobacterium tumefaciens strain C58 (Cereon)
          Length = 355

 Score =  284 bits (726), Expect = 3e-76,   Method: Compositional matrix adjust.
 Identities = 133/233 (57%), Positives = 165/233 (70%)

Query: 24  WGLSSQSTLVFLSHSENTTFLAQDPAARQKLVLRVQRPGYHSPDEIASELAWIDAVIADN 83
           WGLSS++ L  L+ SEN TF   D  + + L++RV RP YH+  EI SELAWIDA+  D 
Sbjct: 48  WGLSSEAKLTLLTISENATFRIADENSGRNLIVRVHRPDYHTEAEILSELAWIDALRQDG 107

Query: 84  VVLTPRPVADREGHLLCPIPLSGATRHVVAFEFLSGKEPDASDDLATWFGELGATSARLH 143
           VV+TPRP++  +G LL         RH VAFE+++GKEPDA  DL  W+  LG  +A+LH
Sbjct: 108 VVVTPRPISANDGSLLQIFSDGETMRHAVAFEYMAGKEPDAESDLVHWYRTLGEINAKLH 167

Query: 144 AHSRRWTMPSTFQRKVWDFDAMLGRRPLWGDWRAGLGLRDDGRRLLQRVADELERRVEAY 203
           AHSRRWT P  F RK W+F+ +LG    WGDWR  LGL+ DG+ +L+R    LE +  AY
Sbjct: 168 AHSRRWTRPENFIRKTWNFNRILGNGAYWGDWRDALGLKPDGKSVLERTHALLETQTSAY 227

Query: 204 GRSEQRFGLVHADLRLANLLVEGDRLGVIDFDDCGFSWFFYDFAAAVSFIEHE 256
           G  E+RFGLVH D+R ANLLV+GDRLGVIDFDDCG SWF YDFAAA+SF+EHE
Sbjct: 228 GYGEERFGLVHCDMRAANLLVDGDRLGVIDFDDCGLSWFAYDFAAAISFMEHE 280


>mlr6716 [R] COG2334 Putative homoserine kinase type II (protein kinase
           fold) Mlo Mesorhizobium loti
          Length = 335

 Score =  196 bits (498), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 107/252 (42%), Positives = 150/252 (59%), Gaps = 8/252 (3%)

Query: 13  MQASLAASLPRWGLSSQSTLVFLSHSENTTFLAQDPAAR--QKLVLRVQRPGYHSPDEIA 70
           +Q +  A+   + L +  ++  ++ SEN T+     AAR  ++  LR+ R GYHS   I 
Sbjct: 16  LQETAEAATANYDLPADVSVDMINLSENATY---KIAARDGRRWALRIHRDGYHSRTAIQ 72

Query: 71  SELAWIDAVIADNVVLTPRPVADREGHLLCPIPLS--GATRHVVAFEFLSGKEPDASDDL 128
           SELAW+  +    +VLTP PVA ++G  +  +  +     RHVV  ++ +G EP   + L
Sbjct: 73  SELAWLTDLRQTGIVLTPVPVAGKDGEQIQRVGHARLAQPRHVVLSQWETGSEPGIGEAL 132

Query: 129 ATWFGELGATSARLHAHSRRWTMPSTFQRKVWDFDAMLGR-RPLWGDWRAGLGLRDDGRR 187
              F  LG  +AR+H H+R+W  PS F R VWDF+  LG  RP WG WR G+G+     R
Sbjct: 133 GEPFELLGEVTARMHIHARQWKRPSWFSRHVWDFETSLGEERPHWGRWRDGIGVDAAKAR 192

Query: 188 LLQRVADELERRVEAYGRSEQRFGLVHADLRLANLLVEGDRLGVIDFDDCGFSWFFYDFA 247
           L  R A+ + RR+ A+G+   RFGL+H DLRLANLL++G  + VIDFDDCGF W+ YD A
Sbjct: 193 LFGRTAELIGRRLAAFGKGHDRFGLIHCDLRLANLLIDGKTVKVIDFDDCGFGWYMYDAA 252

Query: 248 AAVSFIEHEXPA 259
             +SF EHE  A
Sbjct: 253 TPISFYEHEPQA 264


>BMEII0132 [R] COG2334 Putative homoserine kinase type II (protein kinase
           fold) Bme Brucella melitensis
          Length = 306

 Score = 97.1 bits (240), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 71/230 (30%), Positives = 109/230 (47%), Gaps = 20/230 (8%)

Query: 34  FLSHSENTTFLAQ----DPAARQKLVLRVQRPGYHSPDEIASELAWIDAVIADNVVLTPR 89
            L + EN  F  +    +PAA     LR+ RPGYH+   + SELAW+D  +  + +  P+
Sbjct: 4   LLKYRENAVFKVRLRDGNPAA-----LRLHRPGYHARAALVSELAWMDD-LRKHAIAVPQ 57

Query: 90  PVADREGHLLCP-IPLSGATRHVVAFEFLSGKEPDASD--------DLATWFGELGATSA 140
           P+A  +G  L   +   GAT H     ++ G+    +         DL   F  +G   A
Sbjct: 58  PLAALDGAFLVALVSPDGATYHADLIGWVEGEPLGETGTPLSRHGRDLPAVFHAIGGEMA 117

Query: 141 RLHAHSRRWTMPSTFQRKVWDFDAMLGRRPLWGDWRAGLGLRDDGRRLLQRVADELERRV 200
           R+H  +  ++ P+ F+R  WD   +LG  P WG +     L    R  L R+ ++L   V
Sbjct: 118 RMHEAADGFSRPAGFERPAWDVAGLLGDAPFWGRFWDCETLSAQDRIYLSRLREDLS-VV 176

Query: 201 EAYGRSEQRFGLVHADLRLANLLVEGDRLGVIDFDDCGFSWFFYDFAAAV 250
            A    +   GL+HADL   N+ +    +  IDFDDCGF +  +D A  +
Sbjct: 177 LADLAPQLDQGLIHADLVRENVFLRDGSVAFIDFDDCGFGFRLFDLATVL 226


>BS_yerI [R] COG2334 Putative homoserine kinase type II (protein kinase
           fold) Bsu Bacillus subtilis
          Length = 336

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 59/236 (25%), Positives = 111/236 (47%), Gaps = 16/236 (6%)

Query: 14  QASLAASLPRWGLSSQSTLVFLSHSENTTFLAQDPAARQKLVLRVQRPGYHSPDEIASEL 73
           +  LA +  R+G S +  + FL+ +EN  +        Q  +L++      S D +  E+
Sbjct: 15  EQVLAEAAARYGFS-KDQVRFLADAENYVYECM--KDNQPYILKITHTIRRSSDYMMGEM 71

Query: 74  AWIDAVIADNVVLTPRPVADREGHLLCPIPL-SGATRHVVAFEFLSGKEPDASDDLATWF 132
            W+   +A   +   +P+    G  +  +P  +G +  +  +E   G++ D SD   T F
Sbjct: 72  EWLRH-LAIGGISVAKPLPSLNGKDVEAVPDGNGGSFLLRVYEKAPGQKVDESDWNETLF 130

Query: 133 GELGATSARLHAHSRRWTMPS-TFQRKVWDFDAMLGRRPLWGDWRAGLGLRDDGRRLLQR 191
            ELG  +  +H+ ++ + + +  F+R+ WD +  L  R           + +D  ++ Q+
Sbjct: 131 YELGRYTGSMHSLTKSYKLSNPAFKRQEWDEEEQLKLRKY---------VPEDQIKVFQQ 181

Query: 192 VADELERRVEAYGRSEQRFGLVHADLRLANLLVEGDRLGVIDFDDCGFSWFFYDFA 247
            AD L   +    +S+  +GLVHADL   N   +  ++   DFDD G++WF  D +
Sbjct: 182 -ADSLMNELRRLPKSQDNYGLVHADLHHGNFNWDHGKITAFDFDDIGYNWFVNDIS 236