BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0115.0134.p (255 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Rv0222 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu M... 269 5e-72 MT0232 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC M... 269 5e-72 mll8753 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mlo ... 200 2e-51 mll6015 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mlo ... 194 1e-49 MT3617 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC M... 192 6e-49 >Rv0222 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu Mycobacterium tuberculosis H37Rv Length = 262 Score = 269 bits (687), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 149/254 (58%), Positives = 190/254 (74%), Gaps = 2/254 (0%) Query: 2 SEETPVLTEVRGPILIITLNRPEAKNAANLALSKGVAAAIDRLDADDALSVGIITGAGGT 61 + E VL E R ILIIT+NRP+AKNA N A+S+G+A A+D+LD D LSV I+TG GG+ Sbjct: 9 NTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGGGGS 68 Query: 62 FCSGMDLKGFLKGERPSIPGRGFAGLTEAPPKKPLIAAVDGYALAGGMEIALSCDMIVAN 121 FC+GMDLK F +GE + GRG G TE PP KPLIAAV+GYALAGG E+AL+ D+IVA Sbjct: 69 FCAGMDLKAFARGENVVVEGRGL-GFTERPPTKPLIAAVEGYALAGGTELALAADLIVAA 127 Query: 122 RNAKFGIPEVKRGLAAAAGGLIRMPRQMPFRVAMEFALTGEFFGAERAYQLGIINRVTD- 180 R++ FGIPEVKRGL A GGL+R+P ++P+ +AME ALTG+ AERA++LG++N + + Sbjct: 128 RDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEP 187 Query: 181 GPALAAALELAAAIGANGPLAVKASKQVIVESRLWPEDEMWKRQQEIVGPVFVSEDAREG 240 G AL AA+ LA I ANGPLAV A+K++I ESR W D M+ Q +I+ PVF S DA+EG Sbjct: 188 GTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFTSNDAKEG 247 Query: 241 AAAFAEKRPPNWKG 254 A AFAE+R P W G Sbjct: 248 AIAFAERRRPRWTG 261 >MT0232 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC Mycobacterium tuberculosis CDC1551 Length = 262 Score = 269 bits (687), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 149/254 (58%), Positives = 190/254 (74%), Gaps = 2/254 (0%) Query: 2 SEETPVLTEVRGPILIITLNRPEAKNAANLALSKGVAAAIDRLDADDALSVGIITGAGGT 61 + E VL E R ILIIT+NRP+AKNA N A+S+G+A A+D+LD D LSV I+TG GG+ Sbjct: 9 NTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGGGGS 68 Query: 62 FCSGMDLKGFLKGERPSIPGRGFAGLTEAPPKKPLIAAVDGYALAGGMEIALSCDMIVAN 121 FC+GMDLK F +GE + GRG G TE PP KPLIAAV+GYALAGG E+AL+ D+IVA Sbjct: 69 FCAGMDLKAFARGENVVVEGRGL-GFTERPPTKPLIAAVEGYALAGGTELALAADLIVAA 127 Query: 122 RNAKFGIPEVKRGLAAAAGGLIRMPRQMPFRVAMEFALTGEFFGAERAYQLGIINRVTD- 180 R++ FGIPEVKRGL A GGL+R+P ++P+ +AME ALTG+ AERA++LG++N + + Sbjct: 128 RDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEP 187 Query: 181 GPALAAALELAAAIGANGPLAVKASKQVIVESRLWPEDEMWKRQQEIVGPVFVSEDAREG 240 G AL AA+ LA I ANGPLAV A+K++I ESR W D M+ Q +I+ PVF S DA+EG Sbjct: 188 GTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFTSNDAKEG 247 Query: 241 AAAFAEKRPPNWKG 254 A AFAE+R P W G Sbjct: 248 AIAFAERRRPRWTG 261 >mll8753 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mlo Mesorhizobium loti Length = 265 Score = 200 bits (509), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 112/252 (44%), Positives = 153/252 (60%), Gaps = 3/252 (1%) Query: 6 PVLTEVRGPILIITLNRPEAKNAANLALSKGVAAAIDRLDADDALSVGIITGAGGTFCSG 65 PV E R I II +NRP+ +NA + S + A+DR ++DD L+VGI+ G G FCSG Sbjct: 13 PVSFETRDNIAIIAINRPDRRNAIDERTSPQLRIAVDRFESDDHLAVGILRGEGPVFCSG 72 Query: 66 MDLKGFLKGERPSIP-GRG-FAGLTEAPPKKPLIAAVDGYALAGGMEIALSCDMIVANRN 123 MDL+ F+ GE I G G GL KP++AAV G A+AGG E+ L+CD++V+ N Sbjct: 73 MDLQAFVDGEAEEILFGDGHLGGLVSRARTKPVLAAVQGAAIAGGFELMLACDLVVSTEN 132 Query: 124 AKFGIPEVKRGLAAAAGGLIRMPRQMPFRVAMEFALTGEFFGAERAYQLGIINR-VTDGP 182 KFG+PE KRGL A AGG +R+ +P +A E LTG F A RAYQLG++NR V + Sbjct: 133 CKFGLPEAKRGLVAGAGGALRLGEMLPPVLANEILLTGLLFEAPRAYQLGLVNRLVPEHF 192 Query: 183 ALAAALELAAAIGANGPLAVKASKQVIVESRLWPEDEMWKRQQEIVGPVFVSEDAREGAA 242 L AA+ LA +I N PL+V+AS ++ + +W E++ + S DA EGA Sbjct: 193 LLEAAMSLADSIAQNAPLSVRASLALVKAQSEKARNSLWTLNDELLRELMRSNDALEGAT 252 Query: 243 AFAEKRPPNWKG 254 A+ KR P W+G Sbjct: 253 AYKAKRRPIWRG 264 >mll6015 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mlo Mesorhizobium loti Length = 257 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 120/258 (46%), Positives = 158/258 (61%), Gaps = 6/258 (2%) Query: 1 MSEETPVLTEVRGPILIITLNRPEAKNAANLALSKGVAAAIDRLDADDALSVGIITGAGG 60 MS++ P+L E R I +I+LNRPE +NA + LS+ + A D +AD + SV II G G Sbjct: 1 MSDQ-PLLVEKRRDITLISLNRPERRNAVDGKLSRALREAFDHFEADPSASVAIINGQGA 59 Query: 61 TFCSGMDLKGFLKGERPSI---PGRGFAGLTEAPPKKPLIAAVDGYALAGGMEIALSCDM 117 FCSGMDLK FL GE I GR GL KPL+AAV G A+AGG E+ L+CD+ Sbjct: 60 AFCSGMDLKAFLDGEADDILFGEGR-LGGLVSRNLTKPLVAAVHGVAVAGGFELMLACDL 118 Query: 118 IVANRNAKFGIPEVKRGLAAAAGGLIRMPRQMPFRVAMEFALTGEFFGAERAYQLGIINR 177 +V+ +FG+PE KRGL A AGG R+ +P +A E LTGE FGA+RAY+LG++NR Sbjct: 119 VVSADTCRFGLPEAKRGLVAGAGGAFRLGEILPPVIAAEILLTGELFGAQRAYELGLVNR 178 Query: 178 VT-DGPALAAALELAAAIGANGPLAVKASKQVIVESRLWPEDEMWKRQQEIVGPVFVSED 236 + + L AL +A AI N P++ KAS + S W +++ + SED Sbjct: 179 IVPESEVLETALMMARAIALNAPMSRKASLDLARASLATGRSLRWAMNDDLLKTLIASED 238 Query: 237 AREGAAAFAEKRPPNWKG 254 A EGAAAF EKRPP W+G Sbjct: 239 AVEGAAAFNEKRPPVWRG 256 >MT3617 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC Mycobacterium tuberculosis CDC1551 Length = 263 Score = 192 bits (488), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 116/260 (44%), Positives = 156/260 (60%), Gaps = 16/260 (6%) Query: 8 LTEVRGPILIITLNRPEAKNAANLALSKGVAAAIDRLDADDALSVGIITGAGGTFCSGMD 67 L E RG LI+T+NRP A+NA + + + + A DR+D D + I+TGAGG FC+GMD Sbjct: 8 LVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMD 67 Query: 68 LKGFLKGERPSIPGRGFAGLTEAPPK-----------KPLIAAVDGYALAGGMEIALSCD 116 LK ++P PG F + P + KPLIAAV+G A+AGG EI D Sbjct: 68 LKA--ATQKP--PGDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTD 123 Query: 117 MIVANRNAKFGIPEVKRGLAAAAGGLIRMPRQMPFRVAMEFALTGEFFGAERAYQLGIIN 176 + VA +AKFGI E K L G +R+ RQ+P+ +A + LTG A A ++G+I Sbjct: 124 IRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIG 183 Query: 177 RVT-DGPALAAALELAAAIGANGPLAVKASKQVIVESRLWPEDEMWKRQQEIVGPVFVSE 235 V DG AL ALELA AI ANGPLAV+A + I E+ PE+E +K +I VF+S+ Sbjct: 184 HVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVFLSD 243 Query: 236 DAREGAAAFAEKRPPNWKGK 255 DA+EG AFAEKR PN++ + Sbjct: 244 DAKEGPRAFAEKRAPNFQNR 263