BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0113.0102.p         (158 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SMb20699 [V] COG1566 Multidrug resistance efflux pump Sme Sinorh...   177   1e-44
PA1237 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomo...   162   4e-40
PA3136 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomo...   161   5e-40
CC3714 [V] COG1566 Multidrug resistance efflux pump Ccr Caulobac...   149   2e-36
PA5159 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomo...   148   4e-36

>SMb20699 [V] COG1566 Multidrug resistance efflux pump Sme Sinorhizobium
           meliloti
          Length = 365

 Score =  177 bits (448), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 83/134 (61%), Positives = 104/134 (77%), Gaps = 1/134 (0%)

Query: 1   LSETIIRAPVAGIVGNRRVRLGEYVRPGGSLLSIVPVDGVWVVANFKETQISRMRVGQPA 60
           L  T++RAPV G++GNR+VR+G  V PG SLL IVP+D VW+VANFKETQ+  +R GQ A
Sbjct: 229 LESTVVRAPVGGVIGNRQVRVGRLVAPGASLLDIVPLDNVWIVANFKETQLEHIRPGQRA 288

Query: 61  EITVDGYANVRMRGTIDSLSPGSGAAFSLIPPDNATGNFVRIVQRVPVKIRLDHANALHG 120
            IT+DGY +  + G +DS +PGSG+AFSL+P DNATGNFVR+VQRVPVKIR    N L G
Sbjct: 289 SITIDGYKSGALEGVVDSFAPGSGSAFSLLPADNATGNFVRVVQRVPVKIRF-AGNPLSG 347

Query: 121 RLVPGMSVDVSVDL 134
           RL+PG+S  V +DL
Sbjct: 348 RLLPGLSARVEIDL 361


>PA1237 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomonas
           aeruginosa
          Length = 383

 Score =  162 bits (409), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 79/133 (59%), Positives = 101/133 (75%), Gaps = 1/133 (0%)

Query: 1   LSETIIRAPVAGIVGNRRVRLGEYVRPGGSLLSIVPVDGVWVVANFKETQISRMRVGQPA 60
           L +T IRAP AG VG R+VRL +YV PG  LL++VP++  +VVAN+KETQ+ R+R GQP 
Sbjct: 240 LDDTEIRAPFAGRVGQRKVRLRQYVTPGLPLLAVVPLEQAYVVANYKETQLERIRPGQPV 299

Query: 61  EITVDGYANVRMRGTIDSLSPGSGAAFSLIPPDNATGNFVRIVQRVPVKIRLDHANALHG 120
           E+ VD +   R RG +DS++P SGA F+L+PPDNATGNF +IVQR PV+IRLD   A  G
Sbjct: 300 ELEVDTFGR-RWRGRVDSVAPASGAVFALLPPDNATGNFTKIVQRFPVRIRLDADAAERG 358

Query: 121 RLVPGMSVDVSVD 133
           RL+PGMSV  +VD
Sbjct: 359 RLLPGMSVIATVD 371


>PA3136 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomonas
           aeruginosa
          Length = 355

 Score =  161 bits (407), Expect = 5e-40,   Method: Compositional matrix adjust.
 Identities = 75/134 (55%), Positives = 98/134 (73%)

Query: 1   LSETIIRAPVAGIVGNRRVRLGEYVRPGGSLLSIVPVDGVWVVANFKETQISRMRVGQPA 60
           LS T+I +P++G+VG R  R G+YV+ G  LLS+VP + +WV ANFKETQ+ RMR GQ A
Sbjct: 219 LSRTLIHSPISGLVGQRSARNGQYVQVGTHLLSLVPDEDIWVQANFKETQVGRMRDGQKA 278

Query: 61  EITVDGYANVRMRGTIDSLSPGSGAAFSLIPPDNATGNFVRIVQRVPVKIRLDHANALHG 120
            +T D + +  + G IDSL   SGA FSL+PPDNATGNF ++VQR+PVKI  +  N LHG
Sbjct: 279 RLTFDAFPDTPIDGRIDSLFAASGAQFSLLPPDNATGNFTKVVQRIPVKIVFEADNPLHG 338

Query: 121 RLVPGMSVDVSVDL 134
           R+ PGMSV+  V+L
Sbjct: 339 RIRPGMSVEAEVEL 352


>CC3714 [V] COG1566 Multidrug resistance efflux pump Ccr Caulobacter
           vibrioides
          Length = 396

 Score =  149 bits (377), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 70/147 (47%), Positives = 103/147 (70%), Gaps = 1/147 (0%)

Query: 1   LSETIIRAPVAGIVGNRRVRLGEYVRPGGSLLSIVPVDGVWVVANFKETQISRMRVGQPA 60
           L  T+IRAPV+G+VG R VR G+ V+PG +L+S+VP+   +VVANFKETQ++R+R+GQP 
Sbjct: 239 LERTVIRAPVSGVVGARAVRPGQLVQPGVALMSVVPLGQAYVVANFKETQVARLRIGQPV 298

Query: 61  EITVDGYANVRMRGTIDSLSPGSGAAFSLIPPDNATGNFVRIVQRVPVKIRLDHANALHG 120
           EI  D +   ++ G +DS +P +G  F+LIP +NA GNF +I QR+PVKI +D +  L  
Sbjct: 299 EIKADAFGKEKIVGKVDSFAPATGQEFALIPIENAVGNFTKITQRLPVKIAVDRSQ-LGA 357

Query: 121 RLVPGMSVDVSVDLTTHAKPAPGRAPE 147
            L PG+SV++ VD+   + P+   A +
Sbjct: 358 ALRPGLSVEIKVDVRDRSGPSFAEAAQ 384


>PA5159 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomonas
           aeruginosa
          Length = 394

 Score =  148 bits (374), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 72/146 (49%), Positives = 102/146 (69%), Gaps = 1/146 (0%)

Query: 2   SETIIRAPVAGIVGNRRVRLGEYVRPGGSLLSIVPVDGVWVVANFKETQISRMRVGQPAE 61
           + + I APV G V  R V++G+ V+PG +L+++VP+D +W+ ANFKETQ+  MR+GQP E
Sbjct: 209 ARSTIVAPVTGYVAKRSVQVGQRVQPGNALMAVVPLDQIWIDANFKETQLKHMRIGQPVE 268

Query: 62  ITVDGY-ANVRMRGTIDSLSPGSGAAFSLIPPDNATGNFVRIVQRVPVKIRLDHANALHG 120
           I  D Y ++VR  GT+DSL  G+G+AFSL+P  NATGN+++IVQRVPV+I +D       
Sbjct: 269 IRSDLYGSDVRYSGTVDSLGVGTGSAFSLLPAQNATGNWIKIVQRVPVRIHIDPQELQKH 328

Query: 121 RLVPGMSVDVSVDLTTHAKPAPGRAP 146
            L  G+S+DV VDL   + PA  + P
Sbjct: 329 PLRIGLSMDVKVDLHDQSGPALAQQP 354