BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0113.0085.p (1071 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI2023 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta... 554 e-157 SMc02760 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta... 540 e-153 AGc39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta su... 513 e-145 CC3538 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta s... 469 e-131 RC1114 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta s... 382 e-105 >BMEI2023 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Bme Brucella melitensis Length = 1180 Score = 554 bits (1427), Expect = e-157, Method: Compositional matrix adjust. Identities = 364/910 (40%), Positives = 491/910 (53%), Gaps = 41/910 (4%) Query: 3 DAQARASDPKASTFVSANAGSGKTHVLVQRVIRLLLSGVPPEKILCITFTKAAAANMAER 62 DAQARA+DP AS +VSANAGSGKTHVL +RVIRLLL G P KILC+T+TKAAAA M R Sbjct: 13 DAQARAADPSASVWVSANAGSGKTHVLTERVIRLLLEGTDPSKILCLTYTKAAAAVMQNR 72 Query: 63 VFTTLGHWVTLDDAGLDAAIREAGIAHPSATLRREARKLFACALETPGGLKVQTIHALCT 122 VF L W L D L + + P A AR+LFA AL+TPGG+K+QTIHA C Sbjct: 73 VFMRLSEWAVLPDEALAERLEKLERRRPGAARVASARRLFARALKTPGGMKIQTIHAFCE 132 Query: 123 RLLQQFPFEANVPARFAVLDDRDQNEMMERANLAVFLEASRIPDSPIGRALRTAMANAAD 182 +L QFP EAN+ F ++DD Q ++ A + A D + A + A + Sbjct: 133 AILHQFPLEANIAGHFEMMDDLMQAALVGEARRTLLETAYGGGDPALAAAFADVLQAAGE 192 Query: 183 VTFKEVVREACLSRDHFMAWTDAAGNAAAAAAQMSAALGVPSDIRIEDVEREIIDGPNLP 242 + ++ EA R+ + G + A G D R +D+ ++ P Sbjct: 193 TGLQSLLDEAVGRRNGLQLYLAELGVGTHRVEALHRAFGFEPDAREDDLLADLWPVPEFS 252 Query: 243 RASWKEMATLLDTSSKADQ--KQAERLRAALTFTGAAQVDEYLGVFLTDDRAPRA-SVVT 299 + + ++ +S+A Q +RL A V FL P++ S V Sbjct: 253 DDALDLILSIPKGASRAQDFALQLKRLEKASGLPDKIAV--LRAAFLKSTGEPKSGSYVC 310 Query: 300 NNFIKK--------NSVAGHRFEAETDRLGPLIERRRAVVARDRTEALIHIATAAAAHYR 351 + +KK A R E DRL L R + A + L+ Y Sbjct: 311 SAAVKKLLPEFEEEFDTAAARVEMGLDRLKELRLVRLNLAALTLIDNLLQ-------RYH 363 Query: 352 REKLERGLLDYDDLIDKTLAMLDRVSSG-WVHYKLDRGVDHVLIDEAQDTSPRQWDIVAH 410 K RGLLD++DLI +T+A+L R +G WV YKLDRG+DH+L+DEAQDTSP QW ++ Sbjct: 364 DLKRRRGLLDFEDLITRTVALLARNGAGQWVQYKLDRGIDHILVDEAQDTSPDQWQVIRM 423 Query: 411 IISEFTSGAGARDGLVRTVFAVGDEKQSIFSFQGAAPREFDLRRRELKRRFEEAGLKFDP 470 + EF SG G R+ + RT+FAVGDEKQSI+SFQGA P +F + R + + A LKF+ Sbjct: 424 LSEEFFSGLGQRN-VQRTLFAVGDEKQSIYSFQGAVPDDFAEQGRAISIQASNAELKFER 482 Query: 471 VSFTYSFRSGPVILHSVDHVFREQDIFRSIHAVENGYPIHNAMTDAGPSLIELWDLAVAD 530 VS +SFRS P +L +VD VF + R + +G +H+A+ D P IE+WD+ + Sbjct: 483 VSLNFSFRSTPDVLQAVDEVFARPEANRGL----SGATVHSAIRDKEPGEIEIWDMLTPE 538 Query: 531 DRQDIEGWRAPFDGVSVTSPEVKLARRIQAEIKRLVASGTMTGSEGGRRPLSYGDMLILV 590 ++ + WR P D + +P V+LA +I A I+ + G G R ++ D+++LV Sbjct: 539 MVEEPDDWRVPVD--QLAAPAVRLAEQIAATIRYWLDRGEPI--PGQNRKIAPRDIMVLV 594 Query: 591 RRRGNAFDAVIQALKHAGIPVAGADRLKLTEHIAIIDLMNLADALLLPQDDLALAVALKS 650 R+R A+ +ALK+ +PVAGADRL+LT HIAI DLM L +L P DDL+LA LKS Sbjct: 595 RKRDQFMPALSRALKNLSVPVAGADRLQLTSHIAIQDLMALGRFVLQPSDDLSLAALLKS 654 Query: 651 PLFGLDDDDLFKLAYQRRG--SLREALAAQAPTDERFAAALRRLEQCERRFTQETPFAFY 708 PLFG DDD LF LAY R +L E L + D A + L + F FY Sbjct: 655 PLFGWDDDRLFTLAYPRGAGDTLFEYLYRASRHDAELAQIHKLLSRWRNMADTMPVFEFY 714 Query: 709 AWLLGGDGGRARILRRLGHEANDALDEFLELALSYERKAPASLQGFVAWLRAADTEVKRD 768 A +L DG R ++L RLG EA D +DEF ALS ER LQ F+ L AA E+KR+ Sbjct: 715 ARVLSADGARRKLLARLGPEAGDIIDEFQNYALSAERAGLPGLQAFLETLEAAAPEIKRE 774 Query: 769 MEISRDEVRVMTVHGAKGLEASVVFLVDTTTSPSDTQRL-RLIHLPQGNAAPNAPGVVVW 827 ++ RDEVR+MTVH AKGLE +VVFLVD ++ R +LI P G + Sbjct: 775 LDQGRDEVRIMTVHAAKGLEGAVVFLVDPGSAVWTGSRAPKLIPYDFQGDGPPVKGFLWQ 834 Query: 828 AGKKAEDPPNVAEARKAMLGDTEDEYRRLLYVAMTRAADRLIVGGCMPGNMNTVRKS--S 885 + AE K + E+EYRRLLYV MTRA DRLI+ G R+S + Sbjct: 835 PNSSCQTGFTAAEIEK-LKNRAEEEYRRLLYVGMTRAEDRLIICG-----YRGTRESGET 888 Query: 886 WYDLITKGLA 895 W+ L+ LA Sbjct: 889 WHRLVEDALA 898 >SMc02760 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Sme Sinorhizobium meliloti Length = 1189 Score = 540 bits (1390), Expect = e-153, Method: Compositional matrix adjust. Identities = 377/985 (38%), Positives = 503/985 (51%), Gaps = 42/985 (4%) Query: 5 QARASDPKASTFVSANAGSGKTHVLVQRVIRLLLSGVPPEKILCITFTKAAAANMAERVF 64 QA ASDP S +VSANAGSGKTHVL QRVIRLLL+G P ILC+T+TKAAA+ M+ RVF Sbjct: 24 QALASDPACSAWVSANAGSGKTHVLTQRVIRLLLAGCRPSAILCLTYTKAAASEMSNRVF 83 Query: 65 TTLGHWVTLDDAGLDAAIREAGIAHPSATLRREARKLFACALETPGGLKVQTIHALCTRL 124 L W TLDD L+ I P +EAR+LFA ALETPGGLK+QTIHA C L Sbjct: 84 EKLAEWATLDDTTLEKRIEAIEGKRPPTAKIQEARRLFARALETPGGLKIQTIHAFCEAL 143 Query: 125 LQQFPFEANVPARFAVLDDRDQNEMMERANLAVFLEASRIPDSPIGRALRTAMANAADVT 184 L QFP EANV F+VLDDR ++ A A+ + D + A T + A D Sbjct: 144 LHQFPLEANVAGHFSVLDDRAAAVLLADARRALLTATAAASDGELAEAFATVLDLADDTG 203 Query: 185 FKEVVREACLSRDHFMAWTDAAGNAAAAAAQMSAALGVPSDIRIEDVEREI-----IDGP 239 ++++ +R A+ D A A + AALG+ V + ++GP Sbjct: 204 LEKLLAAIVANRAPIQAFLDHASGRGGMEAHLRAALGLEPGETAGTVMAAVWPLAGLNGP 263 Query: 240 NLPRASWKEMATLLDTSSKADQKQAERLRAALTFTGAA-QVDEYLGVFLTDDRAPRASVV 298 L + ++ L + + A+ LRA AA + + + +F P+A Sbjct: 264 ALD--DYIDLGLRLGGAKPS--AIADGLRAVRAIDDAATRYSKLVELFFNGGGKPKAESA 319 Query: 299 TNNFIKKNSVAGHRFEAETDRLGPL--IERRRAVVARDRTEALIHIATAAAAHYRREKLE 356 N + + E R L ++R V T A + +A Y K Sbjct: 320 FLNAAMRRAAPQLELRVEEARSHMLACVDRLSIVQMYGATRAALVLAERLNRDYEALKKA 379 Query: 357 RGLLDYDDLIDKTLAMLDRVSSG-WVHYKLDRGVDHVLIDEAQDTSPRQWDIVAHIISEF 415 R LD++DLI +T A+L R G WVHYKLD+G+DH+L+DEAQDTSP QW I+ + ++F Sbjct: 380 RSQLDFEDLIHRTAALLARSDVGAWVHYKLDQGIDHILVDEAQDTSPAQWTIIQSLAADF 439 Query: 416 TSGAGARDGLVRTVFAVGDEKQSIFSFQGAAPREFDLRRRELKRRFEEAGLKFDPVSFTY 475 +G AR RT+FAVGDEKQSI+SFQGA P F +RR F P+ Sbjct: 440 FAGETARAD-DRTIFAVGDEKQSIYSFQGARPERFSRESTLTERRVRAGNKHFSPIRLQL 498 Query: 476 SFRSGPVILHSVDHVFREQDIFRSIHAVENGYPIHNAMTDAGPSLIELWDLAVADDRQDI 535 SFRS +L +VD VF R + A +H + P ++LWD+ + Sbjct: 499 SFRSTVDVLSAVDTVFANPGNARGLSARSEAI-VHASNRIGQPGAVDLWDVIAPEPAASE 557 Query: 536 EGWRAPFDGVSVTSPEVKLARRIQAEIKRLVASGTMTGSEGGRRPLSYGDMLILVRRRGN 595 E W APFD +P LARRI A ++ + T+ +G RR + GD+++LVR+R Sbjct: 558 EDWTAPFDATPERAPVNILARRIAAVLEDWIGRETVI-EKGVRRAMRPGDVIVLVRKRDA 616 Query: 596 AFDAVIQALKHAG-IPVAGADRLKLTEHIAIIDLMNLADALLLPQDDLALAVALKSPLFG 654 +A+ +ALK G IPVAGADRL LT HIA+ DL+ L +LLP+DDL+LA LKSPL Sbjct: 617 FVNALTRALKRRGNIPVAGADRLVLTSHIAVQDLIALGRFVLLPEDDLSLAALLKSPLLD 676 Query: 655 LDDDDLFKLAYQR---RGSLREALAAQAPTDERFAAALRRLEQCERRFTQETPFAFYAWL 711 L ++D+F+LA +R R A A R+ A+R L + + P FYA + Sbjct: 677 LGEEDVFELAARRTEGESLWRRLRQAGAEETSRYHEAVRTLSRYSGLARELLPHDFYARV 736 Query: 712 LGGDGGRARILRRLGHEANDALDEFLELALSYERKAPASLQGFVAWLRAADTEVKRDMEI 771 LG DGGR L RLG E +D LDEFL AL +ER LQ F++ L VKR+ + Sbjct: 737 LGADGGRRAFLARLGSEVSDILDEFLTFALDHERNGLPGLQAFISTLEIEAPTVKREQDK 796 Query: 772 SRDEVRVMTVHGAKGLEASVVFLVDTTTSPSDTQRLR-LIHLPQGNAAPNAPGVVVWAGK 830 RDEVRVMTVH AKGLEA VVFLVD Q++ L L + + V VW Sbjct: 797 ERDEVRVMTVHAAKGLEAPVVFLVDGGGEAFVRQQVSDLRFLEKAQVDHSTLTVPVWRAP 856 Query: 831 KAEDPPNVAEARKAMLGDTEDEYRRLLYVAMTRAADRLIVGGCMPGNMNTVRKSSWYDLI 890 + +A + + E+EYRRLLYV MTRAADRLIV G NT +W+ ++ Sbjct: 857 GSAPNSLIAADNERLKKLAEEEYRRLLYVGMTRAADRLIVCGYRGQRQNT---DTWHSMV 913 Query: 891 TKGLAN------------------SGLRLEELETPAGKVMRYSRPDDVADLTGATASAAA 932 LA G+ E P R ++ T +A Sbjct: 914 QGTLAQDLKGRGTPRLFRAGSEEWQGIAWREAHVPRDLPTSEGRSEESQRPTAGLPTALF 973 Query: 933 VPIALPSWLRAPAAPEASTASMLRP 957 P A P L P AP +T ++ P Sbjct: 974 TPPAAPRRLPRPLAPSGTTIAIDDP 998 >AGc39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1233 Score = 513 bits (1322), Expect = e-145, Method: Compositional matrix adjust. Identities = 344/920 (37%), Positives = 486/920 (52%), Gaps = 55/920 (5%) Query: 5 QARASDPKASTFVSANAGSGKTHVLVQRVIRLLLSGVPPEKILCITFTKAAAANMAERVF 64 Q ASDP +S +VSANAGSGKTHVL QRVIRLLL+G P ILC+T+TKAAA+ M+ RVF Sbjct: 74 QRLASDPASSAWVSANAGSGKTHVLTQRVIRLLLAGCRPSAILCLTYTKAAASEMSSRVF 133 Query: 65 TTLGHWVTLDDAGLDAAIREAGIAHPSATLRREARKLFACALETPGGLKVQTIHALCTRL 124 L W TL D+ L I P EAR+LFA ALETPGGLK+QTIHA C L Sbjct: 134 DRLAEWATLPDSDLKDRITTIEGKVPDRIKLAEARRLFAKALETPGGLKIQTIHAFCEAL 193 Query: 125 LQQFPFEANVPARFAVLDDRDQNEMMERANLAVFLEASRIPDSPIGRALRTAMANAADVT 184 L QFP EANV F+VLDDR ++ A ++ S D+ + +AL + A + Sbjct: 194 LHQFPLEANVAGHFSVLDDRAATTLLAEARRSLLTAVSTEDDAELVQALAYVLDLADESG 253 Query: 185 FKEVVREACLSRDHFMAWTDAAGNAAAAAAQMSAALGVPSDIRIEDVEREIIDGPNLPRA 244 + ++ +R ++ A + ++ + + + E P L Sbjct: 254 LEALLSAIIANRSALRSFLHEAKQSGGLDVRLRQEMQIAAGETEETAAEAFWPLPGLSGL 313 Query: 245 SWKEMATLLDT-----------SSKADQKQAERLR-------AALTFTGAAQVDEYLGVF 286 TL D + + ++Q + +R A LT G + D Y+ Sbjct: 314 VLDTYLTLADEVGGSRVIEVAYALREAKRQPDPVRRMELIEAALLTAKGEKKSDAYVINK 373 Query: 287 LTDDRAPRASVVTNNFIKKNSVAGHRFEAETDRLGPLIERRRAVVARDRTEALIHIATAA 346 AP +V + ++ V R R R V T++ + +A Sbjct: 374 GMQKSAP--DLVDALTLARDHVVACR------------NRYRLVRMLVATKSALVLAERL 419 Query: 347 AAHYRREKLERGLLDYDDLIDKTLAMLDRVSSG-WVHYKLDRGVDHVLIDEAQDTSPRQW 405 + K +R LD++DLI++ +L+R ++G WVHYKLD+G+DH+L+DEAQDTSP QW Sbjct: 420 IGDFEDLKKQRSQLDFEDLIERAANLLNRDTAGAWVHYKLDQGIDHILVDEAQDTSPVQW 479 Query: 406 DIVAHIISEFTSGAGARDGLVRTVFAVGDEKQSIFSFQGAAPREFDLRRRELKRRFEEAG 465 I+ + ++F +G AR G RT+FAVGDEKQSI+SFQGA P F R E KRR ++ Sbjct: 480 SIIQSLAADFFNGESARMGR-RTLFAVGDEKQSIYSFQGARPERFSQERDETKRRVDQVE 538 Query: 466 LKFDPVSFTYSFRSGPVILHSVDHVFREQDIFRSIHAVENGYPIHNAMTDAG-PSLIELW 524 F + SFRS +L +VD VF + + A + P+ + AG P +E+W Sbjct: 539 QAFHRIRLPLSFRSTEDVLAAVDQVFSDPKNASGLSA--DNEPVEHRSNRAGHPGTVEVW 596 Query: 525 DLAVADDRQDIEGWRAPFDGVSVTSPEVKLARRIQAEIKRLVASGTMTGSEGGRRPLSYG 584 D+ + +D E W APFD + ++P +ARRI A I ++ + T+ +G R + G Sbjct: 597 DMVAPETTEDEEDWTAPFDALRESAPATIVARRIAARIADMIGNQTII-EKGVERAVEPG 655 Query: 585 DMLILVRRRGNAFDAVIQALKH-AGIPVAGADRLKLTEHIAIIDLMNLADALLLPQDDLA 643 D+L+LVR+R +A+ + LK IPVAGADRL+LT+HIA+ DL+ L ++LP+DDL+ Sbjct: 656 DILVLVRKRAAFVNALTRELKRRKNIPVAGADRLRLTDHIAVQDLLALGRFVVLPEDDLS 715 Query: 644 LAVALKSPLFGLDDDDLFKLAYQRRGSLREALAAQAPTDE---RFAAALRRLEQCERRFT 700 LA LKSPLF L +DD+F++A R + Q + E R + +L Sbjct: 716 LAALLKSPLFNLTEDDVFEIAATRSEAESVWQRLQVLSGEETSRLSIVTDKLRHFISLSK 775 Query: 701 QETPFAFYAWLLGGDGGRARILRRLGHEANDALDEFLELALSYERKAPASLQGFVAWLRA 760 T F+A +L GR + L RLG+EA+D LDEFL AL +ER LQ F++ L Sbjct: 776 TATVHDFFAAVLTLHDGRKKFLGRLGNEASDVLDEFLSFALDHERTGLPGLQAFLSVLET 835 Query: 761 ADTEVKRDMEISRDEVRVMTVHGAKGLEASVVFLVDTTT---SPSDTQRLRLIHLPQGNA 817 EVKR+ + R EVR+MTVH +KGLEA VVF+VD + + S +LR + G+A Sbjct: 836 DSPEVKREQDKDRGEVRIMTVHASKGLEAPVVFVVDGGSKAFNHSHVPKLRFVE-GDGDA 894 Query: 818 APNAPGVVVWAGKKAEDPPNVAEARKAMLGDTEDEYRRLLYVAMTRAADRLIVGGCMPGN 877 P VW + + + EDEYRRLLYVAMTRAAD L+V G Sbjct: 895 FP------VWLPGSGFSNHLIRSDEERLKTAAEDEYRRLLYVAMTRAADHLVVCGYRGQK 948 Query: 878 MNTVRKSSWYDLITKGLANS 897 N W+ ++ LA + Sbjct: 949 EN---PECWHAIVKAALAEN 965 >CC3538 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Ccr Caulobacter vibrioides Length = 1203 Score = 469 bits (1208), Expect = e-131, Method: Compositional matrix adjust. Identities = 339/907 (37%), Positives = 460/907 (50%), Gaps = 34/907 (3%) Query: 1 VRDAQARASDPKASTFVSANAGSGKTHVLVQRVIRLLLSGVPPEKILCITFTKAAAANMA 60 + D Q A+DP S FV+ANAG+GKT L+ RV RLLL+GV P+ ILC+T+TKAAAA M Sbjct: 51 MHDPQRIAADPTISAFVTANAGAGKTKTLIDRVARLLLAGVEPQAILCVTYTKAAAAEMQ 110 Query: 61 ERVFTTLGHWVTLDDAGLDAA----IREAGIAHPSATLRREARKLFACALETPGGLKVQT 116 R+F LG W DA L A + EA + + +L +AR LFA ALETPGGLK+QT Sbjct: 111 RRLFDRLGKWSVTSDADLRAELVKLVGEADARYDAKSLS-DARALFAKALETPGGLKIQT 169 Query: 117 IHALCTRLLQQFPFEANVPARFAVLDDRDQNEMMERANLAVFLEASRIPDSPIGRALRTA 176 IHA C +LL++FP EA V F V+DD+ + A AV D+ R + Sbjct: 170 IHAFCEKLLRRFPLEAGVSPGFTVMDDQAGAAIARAARRAVAAWVDSHDDAFSEAYARFS 229 Query: 177 MANAADVTFKEVVREACLSRDHFMAWTDAAGNAAAAAAQMSAALGVPSDIRIEDVEREII 236 +A +F+ + R M + G A A + G ED+ + Sbjct: 230 VALDFQ-SFEAMFAGFEARRGQIMTYVQRCGGLAGAVSDAWRRCGFDGPTSAEDLATRAM 288 Query: 237 DGPNLPRASWKEMATLL-DTSSKADQKQAERLRAALTFTGAAQVDEYLGVFLTD--DRAP 293 +LP +W+ +A++L D K D K AE L AA+ A +D L T+ + P Sbjct: 289 ARLDLP--AWRAVASVLFDGGGKQDAKSAEAL-AAVARDPDATLDLALRALFTEGGEGTP 345 Query: 294 RASVVTNNFIKKNSVAGHRFEAETDRLGPLIERRRAVVARDRTEALIHIATAAAAHYRRE 353 + +K E +L E+ RA + T+ + +A + E Sbjct: 346 ATWPAKTSGLKSREDLREALLLEQAKLEAAREQVRAARVAEDTQNALLLAGLYIERHMAE 405 Query: 354 KLERGLLDYDDLIDKT-LAMLDRVSSGWVHYKLDRGVDHVLIDEAQDTSPRQWDIVAHII 412 K RG LD+ DLIDKT L + ++V + WV YKLD G+DH+L+DEAQDT+P QW+I+ + Sbjct: 406 KEARGALDFTDLIDKTRLLLTEKVEAAWVLYKLDGGIDHILLDEAQDTAPEQWEILRALT 465 Query: 413 SEF----TSGAGARDGLVRTVFAVGDEKQSIFSFQGAAPREFDLRRRELKRRFEEAGLKF 468 ++F TS + RT+F VGDEKQSI+SFQGA P + R E G Sbjct: 466 ADFFVGETSEGWSGRRAERTLFVVGDEKQSIYSFQGADPTRLLEETQGYISRIEAVGAVG 525 Query: 469 DPVSFTYSFRSGPVILHSVDHVFREQDIFRSIHA-VENGYPIHNAMTDAGPSLIELWDLA 527 V T S+RS +L VD +F + D + V H P ++LW L Sbjct: 526 KGVPLTVSYRSTHEVLSFVDALFSDPDTREGVPPPVGQDLVRHELFRHGHPGCVDLWPLT 585 Query: 528 VADDRQDIEGWRAPFDGVSVTSPEVKLARRIQAEIKRLVASGTMTGSE--GGRRPLSYGD 585 +D E W P D S +LA I AE + ++ G + G R GD Sbjct: 586 RELPGEDREAWEKPLDEEGERSANRRLAEAIAAETRAILDRGDAVFDKDLGRHRAAHAGD 645 Query: 586 MLILVRRRGNAFDAVIQALKHAGIPVAGADRLKLTEHIAIIDLMNLADALLLPQDDLALA 645 +L+LVRRR F+ +I+ALK G+PVAGADRL L+ HIA DL+ L +L P DDL LA Sbjct: 646 ILVLVRRRKALFEEIIRALKRRGVPVAGADRLALSSHIAFEDLVALGRFILFPDDDLTLA 705 Query: 646 VALKSPLFGLDDDDLFKLAYQRRGSLREALAAQAPTDERFAAALRRLEQCERRFTQETPF 705 LK+P GL DDD++ LA RRG+L L ++ +AAA L+ + PF Sbjct: 706 ALLKTPFCGLGDDDVYALAKGRRGTLWVELTRRSEERPEWAAARAVLDWALAEGRRRQPF 765 Query: 706 AFYAWLLG-----GDGGRARILRRLGHEANDALDEFLELALSYERKAPASLQGFVAWLRA 760 FYA LG G RA++L RLG EA +ALDEFL + E++ L+ VA A Sbjct: 766 EFYAGWLGLTDADGRSHRAKVLTRLGAEAEEALDEFLAQVMEAEQRGVRDLEALVADFAA 825 Query: 761 ADTEVKRDMEISRDEVRVMTVHGAKGLEASVVFLVDTTTSPSDTQRLRLIHLPQGNAAPN 820 D VKR+ME +R EVRVMT HG+KGLEA +VFL +TT L+ Sbjct: 826 LDIIVKREMEGARREVRVMTAHGSKGLEAPIVFLPETTVKRGAGGSPLLV---------T 876 Query: 821 APGVVVWAGKKAEDPPNVAEARKAMLGDTEDEYRRLLYVAMTRAADRLIVGGCMPGNMNT 880 G ++W D A+ARK E RLLYVA+TRA +RLI+ G + Sbjct: 877 EDGALLWCASGKNDCAVSAKARKLREDKESQEALRLLYVALTRARERLILCGRIDARTKD 936 Query: 881 VRKSSWY 887 + WY Sbjct: 937 DKVGGWY 943 >RC1114 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Rco Rickettsia conorii Length = 822 Score = 382 bits (981), Expect = e-105, Method: Compositional matrix adjust. Identities = 282/911 (30%), Positives = 428/911 (46%), Gaps = 121/911 (13%) Query: 1 VRDAQARASDPKASTFVSANAGSGKTHVLVQRVIRLLLSGVPPEKILCITFTKAAAANMA 60 + D Q ASDP S +VSA+AG+GKT +L R +RLL++GV P ILC+TFT AAA M Sbjct: 1 MSDLQREASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPSNILCLTFTNAAAIEMQ 60 Query: 61 ERVFTTLGHWVTLDDAGLDAAIREAGIAHPSATLRREARKLFACALETPGGLKVQTIHAL 120 R+ + L + + L+ A+ PS A+ L+ L + L + TIHA Sbjct: 61 VRINSRLKYLSLCNAEKLEEALFLMSGNKPSPQDTENAKTLYDKILNSNKLLNIYTIHAF 120 Query: 121 CTRLLQQFPFEANVPARFAVLDDRDQNEMMERANLAVFLEASRIPDSPIGRALRTAMANA 180 C ++L FP EA + F +L E +++ D Sbjct: 121 CQKILNTFPLEAGITPEFKIL------------------EETKLQD-------------- 148 Query: 181 ADVTFKEVVREACLSRDHFMAWTDAAGNAAAAAAQMSAALGVPSDIRIEDVEREIID--- 237 F + E LS +H M L +I ++D+ EII+ Sbjct: 149 ---IFLNIRNEIYLSDEH--------------NDLMKILLNRFHEITLQDIFTEIIEQKI 191 Query: 238 -------GPNLPRASWKEMATLLDTSSKADQKQAERLRAALTFTGAAQVDEYLGVFLTDD 290 +P+ + L + ++ D+ + L A A + +F T D Sbjct: 192 KFRKLFINKQIPKEISNKRLALGELNNIYDK--VKNLFAEYDVEIAPK-----EIFFTKD 244 Query: 291 RAPRASVVTNNFIKKNSVAGHRFEAETDRLGPLIERRRAVVARDRTEALIHIATAAAAHY 350 R S+++ I+K E T + L E RR T L +A Y Sbjct: 245 GKKRKSLLSKELIRKYPKLLLELEKITSEIYRLDELRRIEELEYHTNLLTKLAHIILKKY 304 Query: 351 RREKLERGLLDYDDLIDKTLAMLD-RVSSGWVHYKLDRGVDHVLIDEAQDTSPRQWDIVA 409 K E LLDYDDLI T +L+ + + W+ +KL+ ++H+L+DEAQDTSP QW+I+ Sbjct: 305 DSYKEENNLLDYDDLIYYTEKLLNNKTTHKWLLHKLESEINHILVDEAQDTSPSQWNIIT 364 Query: 410 HIISEFTSGAGARDGLVRTVFAVGDEKQSIFSFQGAAPREFDLRRRELKRRFEEAGLKFD 469 +I+EF + + +VF VGD+KQSIFSFQGA R F+L LK A KF Sbjct: 365 TLITEFNAVERPNN----SVFIVGDDKQSIFSFQGADLRNFNLVNERLKANLTNANKKFK 420 Query: 470 PVSFTYSFRSGPVILHSVDHVFREQDIFRSIHAVENGYP---------IHNAMTDAGPSL 520 ++ YS+RS IL +V + +++ YP I + T G Sbjct: 421 NITLEYSYRSCTEILQFTYNVLKN---------IKSNYPGLFLSNNPLISSFRTHQGS-- 469 Query: 521 IELWDLAVADDRQDIEGWRAPFDGVSVTSPEVKLARRIQAEIKRLVASGTMTGSEGGRRP 580 + +W L ++ ++++ W P D + S L +I IK + S + S R Sbjct: 470 VTVWPLVTSEKQEEL-FWALPEDYENSKSAADLLIEKIVNFIKEQIESEEILPSTAHR-- 526 Query: 581 LSYGDMLILVRRRGNAFDAVIQALKHAGIPVAGADRLKLTEHIAIIDLMNLADALLLPQD 640 +S D +ILVR+R + +I+ L A + V +DR+ L E++ I+DL++LA +LLP D Sbjct: 527 ISEKDFMILVRKRDEFSNNLIKELSKAKLKVEVSDRMNLKENLTIMDLISLAKFVLLPDD 586 Query: 641 DLALAVALKSPLFGLDDDDLFKLAYQR-RGSLREALAAQAPTDERFAAALRRLEQCERRF 699 DL LA LKSP+ G+ + L++L + SL + L++ E L L + + Sbjct: 587 DLNLAGLLKSPIIGISEQQLYELLVNKSENSLWDILSSH----EEIYNKLDSLIEIYKIS 642 Query: 700 TQETPFAFYAWLLGGDGGRARILRRL-GHEANDALDEFLELALSYERKAPASLQGFVAWL 758 E F L LR L +++D ++E L L+ +Y SLQGFVAW Sbjct: 643 IVENFFDLVVHNLN--------LRELYDDDSDDMINELLTLSKNYANDIDNSLQGFVAWF 694 Query: 759 RAADTEVKRDMEISRDEVRVMTVHGAKGLEASVVFLVDTTTSPSDTQRLRLIHLPQGNAA 818 D +KRD+E S D++RVMTVHG+KGLEA +V L D+TT P + + Sbjct: 695 ENNDIYIKRDIEHS-DKIRVMTVHGSKGLEAPIVILCDSTTLPISSNKF----------I 743 Query: 819 PNAPGVVVWAGKKAEDPPNVAEARKAMLGDTEDEYRRLLYVAMTRAADRLIVGGCMPGNM 878 + G + ++ A+ P + E ++A EY RLLYVAMTRA DRLI+ G N Sbjct: 744 WDDKGEMFFSANAADTPEFLQELKEAEKLKDLQEYIRLLYVAMTRAKDRLIICGF--SNK 801 Query: 879 NTVRKSSWYDL 889 +T ++ WY++ Sbjct: 802 STTPENCWYEI 812