BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0113.0082.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc01729 [GER] COG0697 Permeases of the drug/metabolite transpor... 174 2e-43 AGc664 [GER] COG0697 Permeases of the drug/metabolite transporte... 166 6e-41 CC1542 [GER] COG0697 Permeases of the drug/metabolite transporte... 140 4e-33 VC2032 [GER] COG0697 Permeases of the drug/metabolite transporte... 100 4e-21 >SMc01729 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 304 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 108/299 (36%), Positives = 178/299 (59%), Gaps = 9/299 (3%) Query: 8 WIPFTIIAAFGQVARNAMQRHLTGPLGTWGATNIRFLFGLPFSVLFFALAVLLTGDRVPW 67 W+ T+ AAF Q R+AMQ+HL G +GT GAT +RF FGLPF++L+ L + G ++P Sbjct: 4 WVLITVAAAFLQNVRSAMQKHLKGVMGTTGATFVRFGFGLPFALLYLVLLWRVGGHQLPV 63 Query: 68 PAAAFWPWLLTGALSQIVGTGFMLLAMNDRSFVVTTAYMKTEAIQTAIFGFIFLGDHLTT 127 P F+ W + G L+QI T ++ + R+F V TAY +TE Q A+FG IFLG+ + Sbjct: 64 PNGTFYLWAVVGGLAQIAATFLLVHLFSFRNFAVGTAYSRTEPAQAALFGLIFLGEKASQ 123 Query: 128 TKVIAIVIATIGVVITALRPGGQKSFADL-----RPTVLGLGAAAVFAISAVSFRGAIIA 182 ++AI I+ +GV++ ++ + + L R +GL + F +SAVS+R A +A Sbjct: 124 GALVAIAISVVGVMLISVARTTLSARSLLTSIFGRTAGIGLLSGTFFGLSAVSYRSASLA 183 Query: 183 ----VPGVSFVTAASYTLMWSLLVQTLILSVYLLLRAPDVLRSILKLWRPSMFAGFMGAF 238 +P +V AS+TL + +L+QT+++ ++++ R L+ I W+P+ GF+GA Sbjct: 184 LEPSLPQPDYVIQASFTLGFVILLQTIVMLLWIVARERAELKRIGAAWKPAFVVGFVGAS 243 Query: 239 SSQFWFLAFALTAAANVRTLALIEVLFAQGVAYVSLKQPFSLREVFGIVLIVIGVALLI 297 +S WF A L AA V+ +A +E+LF ++ ++ + E+ G +LIV+GV +L+ Sbjct: 244 ASFGWFAAMTLQQAAIVKVVAQVEMLFTFASSFFIFREWINRLELVGCLLIVLGVVMLL 302 >AGc664 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 305 Score = 166 bits (420), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 108/302 (35%), Positives = 174/302 (57%), Gaps = 9/302 (2%) Query: 6 SLWIPFTIIAAFGQVARNAMQRHLTGPLGTWGATNIRFLFGLPFSVLFFALAVLLTGDRV 65 LWI T +AF Q R+ +Q+HL G +GT GAT +RF+FG+PF++ + A L G + Sbjct: 2 ELWIGITFASAFLQNLRSTLQKHLKGMMGTTGATFVRFVFGMPFALAYLAFLHLGLGRPL 61 Query: 66 PWPAAAFWPWLLTGALSQIVGTGFMLLAMNDRSFVVTTAYMKTEAIQTAIFGFIFLGDHL 125 P P +F W GA++QI T ++ + R+F V TAY +TE Q A+F IF+G+ + Sbjct: 62 PVPNMSFAGWATVGAMAQIAATFLLVHLFSFRNFAVGTAYSRTEPAQAALFALIFIGESI 121 Query: 126 TTTKVIAIVIATIGVVI-----TALRPGGQKSFADLRPTVLGLGAAAVFAISAVSFRGAI 180 T + AI I+ GV++ T + P + R +GL + A F +S+V++R A Sbjct: 122 TGGTLAAIAISVAGVMLISVARTQVTPASFLTSIFSRTAGIGLASGAFFGLSSVAYRSAS 181 Query: 181 IA----VPGVSFVTAASYTLMWSLLVQTLILSVYLLLRAPDVLRSILKLWRPSMFAGFMG 236 +A +P + A +TL+ +++QT+ + ++++ R + L I K+W+PS+ GF+G Sbjct: 182 LALAPSLPAPDAMMQAGFTLVVVIVMQTVSMFLWIIWREREELPRIAKVWKPSLAVGFVG 241 Query: 237 AFSSQFWFLAFALTAAANVRTLALIEVLFAQGVAYVSLKQPFSLREVFGIVLIVIGVALL 296 A +S WF A L AA V+ LA +E+LFA + K+ + E+ G +LIV+GV L Sbjct: 242 ATASFGWFTAMTLQQAAVVKALAQVEMLFAFASTVLFFKEKINRLELSGCMLIVVGVLSL 301 Query: 297 IA 298 +A Sbjct: 302 LA 303 >CC1542 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ccr Caulobacter vibrioides Length = 304 Score = 140 bits (352), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 105/291 (36%), Positives = 153/291 (52%), Gaps = 6/291 (2%) Query: 7 LWIPFTIIAAFGQVARNAMQRHLTGPLGTWGATNIRFLFGLPFSVLFFALAVLLTGDRVP 66 +WIP T+ A QVARNA QR + G G WGAT +RFLFGLPF+ LF A+A L+T Sbjct: 14 IWIPITVAATAFQVARNAAQRSIMGEAGPWGATLVRFLFGLPFATLFAAIAWLVTPGATA 73 Query: 67 WPAAAFWPWLLTGALSQIVGTGFMLLAMNDRSFVVTTAYMKTEAIQTAIFGFIFLGDHLT 126 + FW + GA QI T +L AM SF + TA ++ I+G +F GDH+ Sbjct: 74 HASLPFWIACVAGAGLQIAATAALLTAMQRSSFALGTAMQQSGLPFALIWGVLFFGDHVG 133 Query: 127 TTKVIAIVIATIGVVITALRPGGQKSFADLRPTVL--GLGAAAVFAISAVSFRGAIIAVP 184 +IAT+G+ I P G+ +R + GLG+ A+FA+SA FR A +A Sbjct: 134 PVAWAGGLIATLGLAILTW-PRGE---VVMRKDAVWAGLGSGAIFALSANCFRQASLAFE 189 Query: 185 GVSFVTAASYTLMWSLLVQTLILSVYLLLRAPDVLRSILKLWRPSMFAGFMGAFSSQFWF 244 +A T+M +QTL L+ YL R L++++ WR S+ AGF GA +S WF Sbjct: 190 PAHPAASAFVTVMVVQAIQTLALTSYLAWRDRAALKAVIAAWRQSLGAGFCGAAASGLWF 249 Query: 245 LAFALTAAANVRTLALIEVLFAQGVAYVSLKQPFSLREVFGIVLIVIGVAL 295 A L+ VR + ++E+ A K+ + +V ++ +GV + Sbjct: 250 TAMTLSPVGPVRAVGVVEMPIAAIAGRRLFKERLTPLQVVAGLVTAVGVVM 300 >VC2032 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Vch Vibrio cholerae Length = 291 Score = 100 bits (249), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 91/294 (30%), Positives = 149/294 (50%), Gaps = 11/294 (3%) Query: 8 WIPFTIIAAFGQVARNAMQRHLTGPLGTWGATNIRFLFGLPFSVLFFALAVLLTGDRVPW 67 WI T+ AAF Q RNA Q L+G + T G T RFL+ P + ++ +P Sbjct: 3 WIFLTLFAAFMQAWRNAFQSRLSGDVTTAGVTLARFLWASPIAGVYLIALYQWQPAALPT 62 Query: 68 PAAAFWPWLLTGALSQIVGTGFMLLAMNDRSFVVTTAYMKTEAIQTAIFGFIFLGDHLTT 127 ++AFW +++ + QI+ T M+ ++ V K+EA+ AI G +F G LT Sbjct: 63 FSSAFWHYVVGASFMQILATALMVKLFKYNNYAVGAGLAKSEALVAAILGMLFFGTQLTV 122 Query: 128 TKVIAIVIATIGVVITALRPGGQKSFADLRPTV-LGLGAAAVFAISAVSFRGAIIAVPGV 186 + +VI +GV + + GG K + PTV LGL + + FA++++ R A +A + Sbjct: 123 LGWLGVVIGGVGVFMLS-SHGGFKQLS--LPTVLLGLSSGSAFALTSLWVREASLA-SQL 178 Query: 187 SFVTAASYTLMWSLLVQTLILSVYLLLRAPDVLRSILKLW-RPS--MFAGFMGAFSSQFW 243 F +A++ L+ + +QTL L YLL++ L KLW RP M S W Sbjct: 179 PFPYSAAWVLLLVISLQTLCLVGYLLIKERSTLY---KLWQRPKLVMLTSVSSCLGSIGW 235 Query: 244 FLAFALTAAANVRTLALIEVLFAQGVAYVSLKQPFSLREVFGIVLIVIGVALLI 297 F A +L A V+TL +E+ F ++ L Q +++ FG++L+ + L++ Sbjct: 236 FSAMSLQAVPYVKTLGQVEIFFTMLISIFWLGQKVRIKDGFGLILVALAAILVM 289