BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0113.0074.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0036 [E] COG0133 Tryptophan synthase beta chain Pae Pseudomona... 615 e-176 BMEI2018 [E] COG0133 Tryptophan synthase beta chain Bme Brucella... 586 e-167 SMc02766 [E] COG0133 Tryptophan synthase beta chain Sme Sinorhiz... 582 e-166 CC3544 [E] COG0133 Tryptophan synthase beta chain Ccr Caulobacte... 582 e-166 AGc28 [E] COG0133 Tryptophan synthase beta chain Atu Agrobacteri... 580 e-165 >PA0036 [E] COG0133 Tryptophan synthase beta chain Pae Pseudomonas aeruginosa Length = 402 Score = 615 bits (1586), Expect = e-176, Method: Compositional matrix adjust. Identities = 291/391 (74%), Positives = 337/391 (86%), Gaps = 1/391 (0%) Query: 7 NSFRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQAEMNVYLKDYVGRP 66 S+R+GPD +G FG FGG++VAETLMPLILDL + Y AK DPAFQ E+ + +DYVGRP Sbjct: 2 TSYRNGPDAKGLFGRFGGQYVAETLMPLILDLAREYEKAKDDPAFQEELAYFQRDYVGRP 61 Query: 67 SPLYFAERLTEHLGGAKIYLKREELNHTGSHKVNNVLGQIMVARRMGKKRIIAETGAGQH 126 SPLYFAERLTEH GGAKIYLKREELNHTG+HK+NN +GQI++ARRMGKKRIIAETGAG H Sbjct: 62 SPLYFAERLTEHCGGAKIYLKREELNHTGAHKINNCIGQILLARRMGKKRIIAETGAGMH 121 Query: 127 GVATATLCARFGLECVVYMGAVDVERQQPNVIRMEMLGAKVVPVQSGARTLKDAMNDALR 186 GVATAT+ ARFGL+CV+YMG D++RQQ NV RM++LGA+V+PV +G TLKDAMN+ALR Sbjct: 122 GVATATVAARFGLQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGTGTLKDAMNEALR 181 Query: 187 DWVTNVHDTFYCIGTVAGPHPYPMMVRDFQSIIGHETRKQMQEAEGRLPDSLIACIGGGS 246 DWVTNV TFY IGTVAGPHPYP MVRDFQ++IG ETR+Q+ E EGRLPDSL+ACIGGGS Sbjct: 182 DWVTNVDSTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQLAEKEGRLPDSLVACIGGGS 241 Query: 247 NAMGLFHPFLDDPLIEIFGVEAAGHGL-TQLHAASLAGGRPGVLHGNRTYLLMDADGQIE 305 NAMGLFHPFLDD ++I GVEAAGHG+ T HAASL GG PGVLHGNRT+LL DADGQI Sbjct: 242 NAMGLFHPFLDDAGVQIVGVEAAGHGIDTGKHAASLNGGVPGVLHGNRTFLLQDADGQII 301 Query: 306 EAHSISAGLDYPGIGPEHAWLHETGRVKYLSATDEEALAAFQLLSRLEGIIPALESAHAI 365 +AHSISAGLDYPGIGPEHAWLH+TGRV+Y S TD+EAL AF RLEGIIPALES+HA+ Sbjct: 302 DAHSISAGLDYPGIGPEHAWLHDTGRVEYTSITDDEALEAFHTCCRLEGIIPALESSHAL 361 Query: 366 AKLSELAPQRPKDHLMVVNLSGRGDKDVPQV 396 A++ + AP PK+H+MVVNLSGRGDKD+ V Sbjct: 362 AEVFKRAPSLPKEHIMVVNLSGRGDKDMQTV 392 >BMEI2018 [E] COG0133 Tryptophan synthase beta chain Bme Brucella melitensis Length = 422 Score = 586 bits (1510), Expect = e-167, Method: Compositional matrix adjust. Identities = 277/399 (69%), Positives = 331/399 (82%), Gaps = 1/399 (0%) Query: 3 PNLPNSFRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQAEMNVYLKDY 62 P PNS+++GPDE G FGIFGGRFVAETLMPLIL+L++AY AK DP F+AE+N Y Sbjct: 20 PVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFY 79 Query: 63 VGRPSPLYFAERLTEHLGGAKIYLKREELNHTGSHKVNNVLGQIMVARRMGKKRIIAETG 122 GRPS LY+AE L++HLGGAKIY KRE+LNHTGSHK+NN LGQI++A+RMGK RIIAETG Sbjct: 80 AGRPSKLYYAEGLSKHLGGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETG 139 Query: 123 AGQHGVATATLCARFGLECVVYMGAVDVERQQPNVIRMEMLGAKVVPVQSGARTLKDAMN 182 AGQHGVA+AT+ ARFGL C+VY+GA DVERQ+PNV RM++LGA+V PV +G TLKDAMN Sbjct: 140 AGQHGVASATVAARFGLPCIVYVGASDVERQKPNVFRMKLLGAEVKPVSAGNGTLKDAMN 199 Query: 183 DALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQSIIGHETRKQMQEAEGRLPDSLIACI 242 +ALRDWVTNV DT+Y IGT AGPHPYP +VRDFQS+IG E R+Q+ E EGRLPD ++A + Sbjct: 200 EALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIVAAV 259 Query: 243 GGGSNAMGLFHPFLDDPLIEIFGVEAAGHGLT-QLHAASLAGGRPGVLHGNRTYLLMDAD 301 GGGSNA+GLFHPFLDD ++I GVEA G GL + H AS++ GRPGVLHGNRTYLL +AD Sbjct: 260 GGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNAD 319 Query: 302 GQIEEAHSISAGLDYPGIGPEHAWLHETGRVKYLSATDEEALAAFQLLSRLEGIIPALES 361 GQI E HS+SAGLDYPG+GPEH+WL ++GRV Y+ D EAL AFQL +R EGIIPALES Sbjct: 320 GQILEGHSVSAGLDYPGVGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALES 379 Query: 362 AHAIAKLSELAPQRPKDHLMVVNLSGRGDKDVPQVGDIL 400 AHAIA+ ++AP KD +M+VNLSGRGDKDV VG +L Sbjct: 380 AHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGKLL 418 >SMc02766 [E] COG0133 Tryptophan synthase beta chain Sme Sinorhizobium meliloti Length = 406 Score = 582 bits (1500), Expect = e-166, Method: Compositional matrix adjust. Identities = 281/400 (70%), Positives = 327/400 (81%), Gaps = 1/400 (0%) Query: 2 NPNLPNSFRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQAEMNVYLKD 61 P PNSFRSGPDE G FGIFGGRFVAETLMPLILDL+ +A AK DPAF+AE+ Sbjct: 3 QPPKPNSFRSGPDEEGRFGIFGGRFVAETLMPLILDLQDEWARAKNDPAFKAELENLGTH 62 Query: 62 YVGRPSPLYFAERLTEHLGGAKIYLKREELNHTGSHKVNNVLGQIMVARRMGKKRIIAET 121 Y+GRPSPLYFAERLT LGGAKIY KREELNHTGSHK+NN +GQI++A+RMGK RIIAET Sbjct: 63 YIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAET 122 Query: 122 GAGQHGVATATLCARFGLECVVYMGAVDVERQQPNVIRMEMLGAKVVPVQSGARTLKDAM 181 GAGQHGVA+AT+ ARFGL CVVYMGA DVERQ PNV RM++LGA+V PV +G TLKDAM Sbjct: 123 GAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGNGTLKDAM 182 Query: 182 NDALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQSIIGHETRKQMQEAEGRLPDSLIAC 241 N+ALRDWVTNV T+Y IGT AGPHPYP MVRDFQ++IG E ++Q+ EAEGRLPD ++A Sbjct: 183 NEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKQQILEAEGRLPDLVVAA 242 Query: 242 IGGGSNAMGLFHPFLDDPLIEIFGVEAAGHGLT-QLHAASLAGGRPGVLHGNRTYLLMDA 300 +GGGSNA+G+FH FLDD + I GVEA G GL H ASL G PGVLHGNRTYLL D Sbjct: 243 VGGGSNAIGIFHSFLDDEGVRIVGVEAGGKGLDGDEHCASLTAGSPGVLHGNRTYLLQDG 302 Query: 301 DGQIEEAHSISAGLDYPGIGPEHAWLHETGRVKYLSATDEEALAAFQLLSRLEGIIPALE 360 DGQI+E HSISAGLDYPGIGPEHAWL++ GRV+Y+ D EAL AFQ L+RLEGIIPALE Sbjct: 303 DGQIKEGHSISAGLDYPGIGPEHAWLNDIGRVEYVPIMDHEALEAFQTLTRLEGIIPALE 362 Query: 361 SAHAIAKLSELAPQRPKDHLMVVNLSGRGDKDVPQVGDIL 400 +HA+A++ + AP+ KD ++++NLSGRGDKD+ VG IL Sbjct: 363 PSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKIL 402 >CC3544 [E] COG0133 Tryptophan synthase beta chain Ccr Caulobacter vibrioides Length = 410 Score = 582 bits (1499), Expect = e-166, Method: Compositional matrix adjust. Identities = 287/399 (71%), Positives = 332/399 (83%), Gaps = 1/399 (0%) Query: 3 PNLPNSFRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQAEMNVYLKDY 62 P PN + + PD G FG FGGR+VAETLMPL+LDL KAYADAKADP FQA++ Y Y Sbjct: 8 PAKPNDYSAYPDAEGRFGGFGGRYVAETLMPLVLDLGKAYADAKADPEFQAQLKSYNTHY 67 Query: 63 VGRPSPLYFAERLTEHLGGAKIYLKREELNHTGSHKVNNVLGQIMVARRMGKKRIIAETG 122 GRPSPLYFAERLTEH GGAKIY KR+ELNHTGSHK+NN LGQI++A RMGK RIIAETG Sbjct: 68 AGRPSPLYFAERLTEHFGGAKIYFKRDELNHTGSHKINNALGQILLAMRMGKTRIIAETG 127 Query: 123 AGQHGVATATLCARFGLECVVYMGAVDVERQQPNVIRMEMLGAKVVPVQSGARTLKDAMN 182 AGQHGVATAT+CARFGL CVVYMGA DVERQ+PNV RM +LGA+V PV SG TLKDAMN Sbjct: 128 AGQHGVATATVCARFGLPCVVYMGATDVERQKPNVFRMNLLGAEVRPVSSGTGTLKDAMN 187 Query: 183 DALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQSIIGHETRKQMQEAEGRLPDSLIACI 242 +A+RDWVTNVHDT+Y IGT AGPHPYP+MVRDFQS+IG E R+Q+ E EGRLPD+++ACI Sbjct: 188 EAMRDWVTNVHDTYYLIGTAAGPHPYPVMVRDFQSVIGAEAREQILEMEGRLPDAVVACI 247 Query: 243 GGGSNAMGLFHPFLDDPLIEIFGVEAAGHGL-TQLHAASLAGGRPGVLHGNRTYLLMDAD 301 GGGSNA+GLFHPFL D + + GVEAAGHG+ T HAASL GGRPGVLHGNRTYLL D D Sbjct: 248 GGGSNAIGLFHPFLGDEGVRLIGVEAAGHGVSTDKHAASLTGGRPGVLHGNRTYLLQDDD 307 Query: 302 GQIEEAHSISAGLDYPGIGPEHAWLHETGRVKYLSATDEEALAAFQLLSRLEGIIPALES 361 GQI +AHSISAGLDYPGIGPEH++LH+ GR +Y+S TD EAL AF+L S LEGIIPALE Sbjct: 308 GQIIDAHSISAGLDYPGIGPEHSFLHDIGRAEYVSTTDTEALEAFKLCSTLEGIIPALEP 367 Query: 362 AHAIAKLSELAPQRPKDHLMVVNLSGRGDKDVPQVGDIL 400 AHA+A++ E+A + K ++V+NL GRGDKD+ V + L Sbjct: 368 AHALARVGEIAQELGKGKIVVMNLCGRGDKDIFTVAEAL 406 >AGc28 [E] COG0133 Tryptophan synthase beta chain Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 417 Score = 580 bits (1496), Expect = e-165, Method: Compositional matrix adjust. Identities = 278/396 (70%), Positives = 325/396 (82%), Gaps = 1/396 (0%) Query: 6 PNSFRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQAEMNVYLKDYVGR 65 PNSFR+GPDE G FGI+GGRFVAETLMPLILDL+ + AK+DP FQAE+ Y GR Sbjct: 18 PNSFRAGPDEDGRFGIYGGRFVAETLMPLILDLQAEWDKAKSDPEFQAELKYLGTHYTGR 77 Query: 66 PSPLYFAERLTEHLGGAKIYLKREELNHTGSHKVNNVLGQIMVARRMGKKRIIAETGAGQ 125 PSPLYFAERLT LGGAKIY KREELNHTGSHK+NN LGQI++A+RMGK RIIAETGAGQ Sbjct: 78 PSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQ 137 Query: 126 HGVATATLCARFGLECVVYMGAVDVERQQPNVIRMEMLGAKVVPVQSGARTLKDAMNDAL 185 HGVA+AT+ ARFGL CVVYMGA DV RQ PNV RM++LGA+V PV +G TLKDAMN+AL Sbjct: 138 HGVASATVAARFGLPCVVYMGATDVARQAPNVFRMKLLGAEVKPVTAGHGTLKDAMNEAL 197 Query: 186 RDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQSIIGHETRKQMQEAEGRLPDSLIACIGGG 245 RDWVTNV DT+Y IGT AGPHPYP MVRDFQ++IG E + QM EAEGRLPD +IA +GGG Sbjct: 198 RDWVTNVDDTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKAQMLEAEGRLPDMIIAAVGGG 257 Query: 246 SNAMGLFHPFLDDPLIEIFGVEAAGHGLT-QLHAASLAGGRPGVLHGNRTYLLMDADGQI 304 SNA+G+FHPFLDD + I GVEA G GL+ + H AS+ G PGVLHGNRTYLL D DGQI Sbjct: 258 SNAIGIFHPFLDDKNVRIVGVEAGGKGLSGEEHCASITAGSPGVLHGNRTYLLQDGDGQI 317 Query: 305 EEAHSISAGLDYPGIGPEHAWLHETGRVKYLSATDEEALAAFQLLSRLEGIIPALESAHA 364 +E HSISAGLDYPGIGPEH+WL++ GRV+Y+ D EAL AFQ+L+RLEGIIPALE +HA Sbjct: 318 KEGHSISAGLDYPGIGPEHSWLNDIGRVEYVPIMDHEALDAFQMLTRLEGIIPALEPSHA 377 Query: 365 IAKLSELAPQRPKDHLMVVNLSGRGDKDVPQVGDIL 400 +A++ + AP+ KD ++++NLSGRGDKDV V L Sbjct: 378 LAEVIKRAPKMGKDEIILMNLSGRGDKDVHTVSKFL 413