BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0113.0052.p (426 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AF0907 [GEPR] COG0477 Permeases of the major facilitator superfa... 110 4e-24 MA4166 [GEPR] COG0477 Permeases of the major facilitator superfa... 100 8e-21 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 73 2e-12 RSp0828 [GEPR] COG0477 Permeases of the major facilitator superf... 70 8e-12 SA2300 [GEPR] COG0477 Permeases of the major facilitator superfa... 66 1e-10 >AF0907 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 419 Score = 110 bits (276), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 86/356 (24%), Positives = 161/356 (45%), Gaps = 14/356 (3%) Query: 31 YAIAFLQRVSPQSVSLSFMHDFNTDAAGVAMLASSYFWGYTLMQIPAGLLVDRYGVKRVV 90 Y + R S ++ + M +F A V +L+S+YF+ Y LMQIP G L D G + Sbjct: 31 YFFVYFHRTSSAILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYLSDTKGPRLTT 90 Query: 91 LVSMIASSLGSAAFALAPNLLDVFVARLIVACGDALVFTALLKLVAQSFADERFGMMSGI 150 V + + +G+ FA++PN + R ++ G + V+ +KL+++ F + F ++G+ Sbjct: 91 TVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGV 150 Query: 151 SQVSGYVGGVIATTPLAAAVSGFGWRACFLFIACIGLANLAFAKLALKPDPASHSNKTLK 210 G +G +++ PLA VS FGWR FLFI I + ++ P K+ + Sbjct: 151 LFAVGNMGALVSAYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSRE 210 Query: 211 GVVIAA--RQSLAHVANWGCAMTFASHFAVVTTLSGVWGIPMVAHFFHISPTAAGTPLLA 268 G A R + + W A + + +V G+WG P + + + AG L+ Sbjct: 211 GGRFATNFRVVVLNPVVWLIATSAFLRYGIVMGYQGLWGGPYLMDVYGMQREEAGGVLMM 270 Query: 269 FMIGNALGSIFLGHAADRAAAALDRALIGICVLRMLLIAMLL-----PPIAQTFGLAYVT 323 +G LG+ +G +D+ L+ + +A L+ + Q + ++++ Sbjct: 271 VGLGTILGAPIIGFLSDKVFRTRKWFLVAAGIGFTFTMAPLVFFTASLTVFQLYAISFLI 330 Query: 324 VVFTALGLVAGGTVPLVLKCVKKLYTADLIGVGASVNTTAAGIFAGISQPIIGFAM 379 +F+A G P+ +K+ Y ++ G+ S+ + Q +G+ M Sbjct: 331 GLFSAAG-------PVAYALIKESYPLEVTGLATSIVNVFPFFGGALFQVFMGYLM 379 >MA4166 [GEPR] COG0477 Permeases of the major facilitator superfamily Mac Methanosarcina acetivorans str.C2A Length = 444 Score = 100 bits (248), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 82/296 (27%), Positives = 135/296 (45%), Gaps = 30/296 (10%) Query: 27 VAIAYAIAFLQRVSPQSVSLSFMHDFNTDAAGVAMLASSYFWGYTLMQIPAGLLVDRYGV 86 +A AY + RVS V+ M+ F AA + +L S+YF+ YT MQ+P+G+L D +GV Sbjct: 11 LAFAYFFVYFHRVSTAVVAADIMNTFGVGAASIGLLGSAYFYAYTAMQLPSGILSDSWGV 70 Query: 87 KRVVLVSMIASSLGSAAFALAPNLLDVFVARLIVACGDALVFTALLKLVAQSFADERFGM 146 K+ V + +++G+ +A N V + R+++ G A+V+ ++K++A F F Sbjct: 71 KKTAGVFTLLAAVGAVLTGVASNFTMVLIGRVLIGIGVAMVYIPVMKVLAIWFKKNEFAS 130 Query: 147 MSGISQVSGYVGGVIATTPLAAAVSGFG-WRACFLFIACIG--LANLAFAKLALKPD--- 200 MSG+ G +G + A PLA + FG W+ FL + LA F + KP+ Sbjct: 131 MSGVLLAIGNIGALSAAGPLAIMAAAFGDWQKVFLMLGLFSVLLAVAIFVLVKDKPEEMG 190 Query: 201 -----------------PASHSNKTLKGVVIAARQSLAH-VANWGCAMTFASHFAVVTTL 242 P K G A RQ+ + + W ++ F + + Sbjct: 191 CPTIPEIEAYEKGERYIPPKAVEKIPMGE--ALRQTFSSGMKFWPLSIWFFFMYGSLMVY 248 Query: 243 SGVWGIPMVAHFFHISP-TAAGTPLLAFM-IGNALGSIFLGHAADRAAAALDRALI 296 G+WG P T AG +L+F+ IG G G+ +D+ + + LI Sbjct: 249 QGLWGGPFFRDVLGWDQGTYAG--ILSFIAIGMIFGCPIAGYLSDKVLKSRKKVLI 302 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 72.8 bits (177), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 86/184 (46%), Gaps = 4/184 (2%) Query: 22 LAWTAVAIAYAIAFLQRVSPQSVSLSFMHDFNTDAAGVAMLASSYFWGYTLMQIPAGLLV 81 L W A+AI Y + R + + +F+ A + ++ S++FW Y L+Q+PAG+L Sbjct: 20 LMWAAIAINY----IDRTVLSAAAPHIQKEFHLSAVEMGVVMSAFFWSYALLQLPAGILA 75 Query: 82 DRYGVKRVVLVSMIASSLGSAAFALAPNLLDVFVARLIVACGDALVFTALLKLVAQSFAD 141 DR+G K+V+ +++ SL +A LA + R+ + G+A + + + ++ F Sbjct: 76 DRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGEAGAYPSNAGITSRWFPK 135 Query: 142 ERFGMMSGISQVSGYVGGVIATTPLAAAVSGFGWRACFLFIACIGLANLAFAKLALKPDP 201 + ++ I +G IA +A + F W+ F +G+ L + P Sbjct: 136 QERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVVWALVFRDSP 195 Query: 202 ASHS 205 A H Sbjct: 196 AEHE 199 >RSp0828 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 450 Score = 70.5 bits (171), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 62/213 (29%), Positives = 93/213 (43%), Gaps = 12/213 (5%) Query: 4 LGQQAVYAPTARFTDRA-YLAWTAVAIAYAIAFLQRVSPQSVSLSFMHDFNTDAAGVAML 62 +G Q+V P T R ++ + I I + R + + D DA + + Sbjct: 8 VGAQSV--PRTERTSRVRFMILAMLFIVTTINYADRATISMAGSAMQKDLGIDAVSLGYI 65 Query: 63 ASSYFWGYTLMQIPAGLLVDRYGVKRVVLVSMIASSL-----GSAAF--ALAPNLLDVFV 115 S++ W Y + QIP G L+DR+G +RV S++ SL G+ F +A +L VF Sbjct: 66 FSAFGWAYVIAQIPGGWLLDRFGSRRVYSFSILLWSLFTLMQGTIGFFTGMAAIVL-VFF 124 Query: 116 ARLIVACGDALVFTALLKLVAQSFADERFGMMSGISQVSGYVGGVIATTPLAAAVSGFGW 175 R +V +A F A ++VA F G S I + Y VI +A V FGW Sbjct: 125 LRFMVGVAEAPSFPANSRIVAAWFPANERGTASAIFNSAQYAATVIFAPLMAWLVHAFGW 184 Query: 176 RACFLFIACIGLANLAFAKLALKPDPASHSNKT 208 F+ + IG+ +A A DP H T Sbjct: 185 HYVFIVMGVIGIV-MALAWKRFMHDPKDHPRIT 216 >SA2300 [GEPR] COG0477 Permeases of the major facilitator superfamily Sau Staphylococcus aureus N315 Length = 425 Score = 66.2 bits (160), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 51/240 (21%), Positives = 102/240 (42%), Gaps = 14/240 (5%) Query: 33 IAFLQRVSPQSVSLSFMHDFNTDAAGVAMLASSYFWGYTLMQIPAGLLVDRYGVKRVVLV 92 IA++ R + ++ M D +LAS + GY LMQ+P+G+L +++G ++++ + Sbjct: 22 IAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITI 81 Query: 93 SMIASSLGSAAFALAPNLLDVFVARLIVACGDALVFTALLKLVAQSFADERFGMMSGISQ 152 +++ S + + N +++ R + G+A ++ + + F+ G S Sbjct: 82 ALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALL 141 Query: 153 VSGYVGGVIATTPLAAAVSGFGWRACFLFIACIGLANLAFAKLALKPDPASHS--NKTLK 210 Y G V+A A V+ F W+A F +G+ + K P H N+ K Sbjct: 142 AGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEK 201 Query: 211 GVVIAARQSLAHVAN---WGCAMTFASHFAV---------VTTLSGVWGIPMVAHFFHIS 258 ++ R +A + W S +A+ + TL +W + FH++ Sbjct: 202 RFIMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVN 261