BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0113.0012.p (468 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5392_1 [R] COG0596 Predicted hydrolases or acyltransferases (... 231 3e-60 mll5743 [R] COG0596 Predicted hydrolases or acyltransferases (al... 192 2e-48 mll1900 [R] COG0596 Predicted hydrolases or acyltransferases (al... 174 5e-43 MT1951_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins ... 161 3e-39 Rv1900c_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 161 3e-39 >mll5392_1 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Mlo Mesorhizobium loti Length = 276 Score = 231 bits (588), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 128/274 (46%), Positives = 167/274 (60%), Gaps = 5/274 (1%) Query: 31 ETQYAQSGDFNIAYQVMGDGPTDIILVPGIISHIDFQHELPGYTRFLRRLAKFSRVVTFD 90 ET+YA SG+ IAYQV+G G D++ VPG IS++D E GYTR LRRL+ FSR++ FD Sbjct: 5 ETRYALSGEARIAYQVVGQGSLDLVFVPGFISNLDLHWEDEGYTRLLRRLSAFSRLILFD 64 Query: 91 KRGQGLSDRL--ADVPSLEERIDDVRTIMDAINSKRAALVGFSEGASMSVLFATTYPERV 148 KRG GLSDR+ ++PSLE R+DDVR +MDA S RAAL+G SEGA M++LFA TYPER Sbjct: 65 KRGTGLSDRVDAHNLPSLETRMDDVRAVMDAAGSGRAALLGASEGAPMAMLFAATYPERT 124 Query: 149 SHLVLFGGLARISDLLPPNLTPSEVQERLAYVVKSWGNGDFLKRVFASDAGNPEILARIA 208 L L+GG A + P P + +A +WG G L + A Sbjct: 125 RALALYGGYAHFHKWVMP---PERLNAFIATAETAWGTGATLPNFAPGRVDDAHFTQWWA 181 Query: 209 KFEKLGSSPGALKSYILSNRRIDINPILPVVRTPTLVLHRTTDAQVPVTLGRKLAAGIPG 268 +FE+L +SP A + N ID+ +L + PTL++HR DA+V R LA IP Sbjct: 182 RFERLSASPTAAAALARMNAEIDVRGVLAAISAPTLLIHRRNDARVDPDASRFLAKKIPN 241 Query: 269 AKYIEYPSGDHAFWTGDIERVTGDIEEFITGQRA 302 A+ +E P DH WTGD++RV IEEF+TG RA Sbjct: 242 ARLVEIPGRDHPIWTGDVDRVADLIEEFLTGTRA 275 >mll5743 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Mlo Mesorhizobium loti Length = 285 Score = 192 bits (487), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 107/271 (39%), Positives = 146/271 (53%), Gaps = 2/271 (0%) Query: 30 PETQYAQSGDFNIAYQVMGDGPTDIILVPGIISHIDFQHELPGYTRFLRRLAKFSRVVTF 89 PET Y +SG ++AYQV G GP D++ V G +S++D+ E P LRRL F R+V Sbjct: 7 PETHYVKSGGVSVAYQVTGGGPFDLVYVQGWVSNLDYAWESPRLAHVLRRLGSFCRLVRI 66 Query: 90 DKRGQGLSDRLADVPSLEERIDDVRTIMDAINSKRAALVGFSEGASMSVLFATTYPERVS 149 DKRG GLSDR P+L+ER DDVR ++DAI S+RA L G SEG + +LFA TYPER Sbjct: 67 DKRGTGLSDRNVGFPTLQERADDVRAVLDAIGSRRAVLFGSSEGGVLCMLFAATYPERTQ 126 Query: 150 HLVLFGGLAR--ISDLLPPNLTPSEVQERLAYVVKSWGNGDFLKRVFASDAGNPEILARI 207 L+L G A+ S P T +++E LA + + WG L R S A + Sbjct: 127 ALILHGAYAQGLWSPDYPWAKTREDMEEELAEIERKWGEPWDLGRGAPSLANDTREQQWF 186 Query: 208 AKFEKLGSSPGALKSYILSNRRIDINPILPVVRTPTLVLHRTTDAQVPVTLGRKLAAGIP 267 A + + +SP + +D+ IL + PTL+LHR D V V L+ I Sbjct: 187 AAYLRSSASPSDAIALWRWGAEVDVRNILHAIHVPTLILHRKGDRWVKVEEALYLSERIA 246 Query: 268 GAKYIEYPSGDHAFWTGDIERVTGDIEEFIT 298 GA IE P DH W D +R+ I+ ++ Sbjct: 247 GATLIELPGDDHLIWGADSDRLVDTIQHYLA 277 >mll1900 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Mlo Mesorhizobium loti Length = 274 Score = 174 bits (440), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 98/259 (37%), Positives = 143/259 (55%), Gaps = 2/259 (0%) Query: 29 LPETQYAQSGDFNIAYQVMGDGPTDIILVPGIISHIDFQHELPGYTRFLRRLAKFSRVVT 88 +P T+Y +IAYQ +G GP DI+LVPG ISH++ E +L +++ R++ Sbjct: 1 MPRTRYVAVDGIHIAYQTIGSGPADIVLVPGFISHVERIWEDRSCRAWLTAVSRLGRLIL 60 Query: 89 FDKRGQGLSDRLADVPSLEERIDDVRTIMDAINSKRAALVGFSEGASMSVLFATTYPERV 148 FD+RG GLSDR+ P++E D+ +MDA S+RA LVG SEG + FA +P+R+ Sbjct: 61 FDRRGMGLSDRVGARPTVEATARDILAVMDAAGSRRAVLVGASEGGPGCIRFAVDHPDRL 120 Query: 149 SHLVLFGGLARISDL--LPPNLTPSEVQERLAYVVKSWGNGDFLKRVFASDAGNPEILAR 206 + LVL+G LA+ S P LT ++ ++ WG ++ S A + + A Sbjct: 121 TGLVLWGSLAKGSRAPDYPFALTSAQYDLWQQRLLAGWGGPAEIETFAPSVASDRQARAW 180 Query: 207 IAKFEKLGSSPGALKSYILSNRRIDINPILPVVRTPTLVLHRTTDAQVPVTLGRKLAAGI 266 A + SSPGA+ + + R D+ P+L V TLVLHR D V V GR LA I Sbjct: 181 WAGLLRAASSPGAVAGLLQALRDADVRPLLSKVSAKTLVLHRRGDRAVRVEAGRYLAGRI 240 Query: 267 PGAKYIEYPSGDHAFWTGD 285 GA+++E DH FW G+ Sbjct: 241 AGARFVEVEGEDHWFWVGE 259 >MT1951_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) MtC Mycobacterium tuberculosis CDC1551 Length = 176 Score = 161 bits (408), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 82/163 (50%), Positives = 108/163 (66%), Gaps = 4/163 (2%) Query: 305 GIDLERILATVLFTDIVGSTNLALQLGDHRWRDLLDNHDDRSGRIVSKHRGTLVKSTGDG 364 G D ER+LAT++FTDIVGST A LGD RWRDLLDNHD + + G V + GDG Sbjct: 2 GADAERMLATIMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGREVNTAGDG 61 Query: 365 VLATFDGPGRAVRCALALSEESKSIGLPVRAGLHCGEVEIR----GNDIGGIAVHAAARV 420 +ATF P A+ CA + + ++G+ VR G+H GEVE+R G D+ G+AVH ARV Sbjct: 62 FVATFTSPSAAIACADDIVDAVAALGIEVRIGIHAGEVEVRDASHGTDVAGVAVHIGARV 121 Query: 421 MSQSGSNEVFVSRVVTDLVAGTDLKFSERGSYELKGLPGKWDL 463 + +G +EV VS V D+VAG+ +F+ERG ELKG+PG+W L Sbjct: 122 CALAGPSEVLVSSTVRDIVAGSRHRFAERGEQELKGVPGRWRL 164 >Rv1900c_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Mtu Mycobacterium tuberculosis H37Rv Length = 176 Score = 161 bits (408), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 82/163 (50%), Positives = 108/163 (66%), Gaps = 4/163 (2%) Query: 305 GIDLERILATVLFTDIVGSTNLALQLGDHRWRDLLDNHDDRSGRIVSKHRGTLVKSTGDG 364 G D ER+LAT++FTDIVGST A LGD RWRDLLDNHD + + G V + GDG Sbjct: 2 GADAERMLATIMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGREVNTAGDG 61 Query: 365 VLATFDGPGRAVRCALALSEESKSIGLPVRAGLHCGEVEIR----GNDIGGIAVHAAARV 420 +ATF P A+ CA + + ++G+ VR G+H GEVE+R G D+ G+AVH ARV Sbjct: 62 FVATFTSPSAAIACADDIVDAVAALGIEVRIGIHAGEVEVRDASHGTDVAGVAVHIGARV 121 Query: 421 MSQSGSNEVFVSRVVTDLVAGTDLKFSERGSYELKGLPGKWDL 463 + +G +EV VS V D+VAG+ +F+ERG ELKG+PG+W L Sbjct: 122 CALAGPSEVLVSSTVRDIVAGSRHRFAERGEQELKGVPGRWRL 164