BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0109.0004.p (468 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Ta0334 [GEPR] COG0477 Permeases of the major facilitator superfa... 119 1e-26 TVN0436 [GEPR] COG0477 Permeases of the major facilitator superf... 112 2e-24 PA3467 [GEPR] COG0477 Permeases of the major facilitator superfa... 107 7e-23 ygcS [GEPR] COG0477 Permeases of the major facilitator superfami... 103 8e-22 SSO2505 [GEPR] COG0477 Permeases of the major facilitator superf... 103 9e-22 >Ta0334 [GEPR] COG0477 Permeases of the major facilitator superfamily Tac Thermoplasma acidophilum Length = 445 Score = 119 bits (298), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 72/244 (29%), Positives = 126/244 (51%), Gaps = 17/244 (6%) Query: 142 RLDNLSWSRFHTRVVLALGITWILDGLEVTLAGALSGALKDSPT-MSFSNADVGLASSAY 200 +DN+ FH ++ + + LDG ++++ ++ A+ P + FS + L + + Sbjct: 6 EMDNMRMRPFHRKMEILASMGMFLDGYDLSV---IAMAILLMPIQLKFSKPEYILVNVSA 62 Query: 201 LAGAVLGALGFGWLTDRIGRKKLFFITLALYLSATAATALSWNVASYALFRFLTGAGIGG 260 LAG ++GA G L+DRIGRKK+F I L L++ L+ N + RF+ G GIGG Sbjct: 63 LAGMIVGAPLLGRLSDRIGRKKIFDIDLILFVVFAITAGLATNFWMMFISRFMLGVGIGG 122 Query: 261 EYTAINSTIQELVPARYRGWTDLVINGSFWIGAAIGALSAIILLDPAFLAPDHGWRIAYF 320 +Y ++ + E P + RG + G +W+G+ +++ F + WR + Sbjct: 123 DYPISSTIVSEFAPVKRRGTLLYAMVGMYWLGSLFSG-----IMNYTFAFTYYFWRYTFI 177 Query: 321 TGAVLGLVVLLMRMWIPESPRWLMIHGRPEEAHKIVADI--------ETSVLGHEQPSAD 372 G ++ + ++ +RM IPESPRWL+ GR +EA K++ +I E + G E+ S Sbjct: 178 IGGIVAIPIISLRMQIPESPRWLVSQGRADEASKVIENITGKEPDLNEGVIEGKEERSVR 237 Query: 373 FEKI 376 F + Sbjct: 238 FRDL 241 >TVN0436 [GEPR] COG0477 Permeases of the major facilitator superfamily Tvo Thermoplasma volcanium Length = 445 Score = 112 bits (280), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 69/234 (29%), Positives = 119/234 (50%), Gaps = 9/234 (3%) Query: 143 LDNLSWSRFHTRVVLALGITWILDGLEVTLAGALSGALKDSPT-MSFSNADVGLASSAYL 201 +D + FH ++ + + LDG ++++ ++ A+ PT + F D L + + Sbjct: 7 MDRMGIRPFHRKIEILASMGMFLDGYDLSV---ITMAILLMPTQLHFGKLDYILVNVSAF 63 Query: 202 AGAVLGALGFGWLTDRIGRKKLFFITLALYLSATAATALSWNVASYALFRFLTGAGIGGE 261 G ++GA G L+DRIGRKK+F I L L++ L+ N A + R + G GIGG+ Sbjct: 64 IGMIIGAPLLGRLSDRIGRKKIFGIDLLLFVVFAITAGLATNFAMLFISRLMLGIGIGGD 123 Query: 262 YTAINSTIQELVPARYRGWTDLVINGSFWIGAAIGALSAIILLDPAFLAPDHGWRIAYFT 321 Y ++ + E P RG + G +W+G+ A +++ F + WR + Sbjct: 124 YPISSTMVSEFSPVSKRGTLLYGMVGMYWLGSFFSA-----VMNYTFAFTPYFWRYTFIV 178 Query: 322 GAVLGLVVLLMRMWIPESPRWLMIHGRPEEAHKIVADIETSVLGHEQPSADFEK 375 G V+ + ++ +RM IPESPRWL+ HG + A +V D+ E+ A+ E+ Sbjct: 179 GGVIAIPIIFLRMRIPESPRWLIGHGMTKSAESVVEDLTGRKPDVEEGKAEAEQ 232 >PA3467 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 455 Score = 107 bits (266), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 73/224 (32%), Positives = 118/224 (52%), Gaps = 10/224 (4%) Query: 142 RLDNLSWSRFHTRVVLALGITWILDGLEVTLAGALSGALKDSPTMSFSNADVGLASSAYL 201 RL+ L S +H V + + + + D +++ + L G++K +A GL +S+ Sbjct: 11 RLERLPLSPYHRLVFVIIALAFFFDSMDLAMMTFLLGSIKAE--FGLDSAQAGLLASSSF 68 Query: 202 AGAVLGALGFGWLTDRIGRKKLFFITLALYLSATAATALSWNVASYALFRFLTGAGIGGE 261 G V+GA G L DR GRK +F ++ L+ A+ + + ++ S +R L G G+G E Sbjct: 69 FGMVIGAALSGMLADRFGRKPVFQASIVLWGLASYLCSTAGDLDSLTFYRVLLGIGMGME 128 Query: 262 YTAINSTIQELVPARYRGWTDLVINGSFWIG-AAIGALSAIILLDPAFLAPDHGWRIAYF 320 + S + E++PA RG +++G + +G A G LS FL P GWR + Sbjct: 129 FPIAQSLLSEMIPASRRGKYIALMDGFWPLGFVAAGCLS-------YFLLPLTGWRSIFL 181 Query: 321 TGAVLGLVVLLMRMWIPESPRWLMIHGRPEEAHKIVADIETSVL 364 A+ + VL +R IPESPRWL GR E+A +++ DIE V+ Sbjct: 182 VLALPAVFVLAIRFLIPESPRWLEQAGRREQADRVLRDIEARVM 225 >ygcS [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 469 Score = 103 bits (257), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 125/256 (48%), Gaps = 18/256 (7%) Query: 129 PDDDRIIETSIPVRLDNLSWSRFHTRVVLALGITWILDGLEVTLAGALSGALKDSPTMSF 188 PD++ + + PVR+D+L +RFH R+ + DG + + G ++ +P M Sbjct: 18 PDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIG--YAIIQLTPAMQL 75 Query: 189 SNADVGLASSAYLAGAVLGALGFGWLTDRIGRKKLF-----FITLALYLSATAATALSWN 243 + G+ + L G LG+L GW++D IGR+K+F ITLA +L A T Sbjct: 76 TPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP---- 131 Query: 244 VASYALFRFLTGAGIGGEYTAINSTIQELVPARYRGWTDLVINGSFWIGAAIGALSAIIL 303 R L G G+GG+Y+ ++ + E P R+RG ++ G+F + +G + A I Sbjct: 132 -EHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRG----ILLGAFSVVWTVGYVLASIA 186 Query: 304 LDPAFLAPDHGWRIAYFTGAVLGLVVLLMRMWIPESPRWLMIHGRPEEAHKIVADI--ET 361 WR + A+ L++ L+R PESPRWL+ GR EAH IV Sbjct: 187 GHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPH 246 Query: 362 SVLGHEQPSADFEKIR 377 +LG E +A + I+ Sbjct: 247 VLLGDEVVTATHKHIK 262 >SSO2505 [GEPR] COG0477 Permeases of the major facilitator superfamily Sso Sulfolobus solfataricus Length = 489 Score = 103 bits (257), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 83/276 (30%), Positives = 130/276 (47%), Gaps = 10/276 (3%) Query: 170 VTLAGALSGALKDSPTMSFSNA-DVGLASSAYLAGAVLGALGFGWLTDRIGRKKLFFITL 228 +TL A+ P + F NA L +S L G + G+LG G+L DRIGR+ + IT+ Sbjct: 50 ITLYDAVGNIGAALPYIPFINASQASLIASLGLFGYIPGSLGLGYLADRIGRRTVLIITV 109 Query: 229 ALYLSATAATALSWNVASYALFRFLTGAGIGGEYTAINSTIQELVPARYRGWTDLVINGS 288 L + ALS N A+FRF+ GAGIGG+ + E P+ RG I + Sbjct: 110 LLTAIGSLGMALSINFPMLAIFRFIEGAGIGGDLNLAMVYVSEFAPSAKRGKYANWIYLA 169 Query: 289 FWIGAAIGALSAIILLDPAFLAPDHGWRIAYFTGAVLGLVVLLMRMWIPESPRWLMIHGR 348 WI +GA A +L+ P GWR+A+ A++ + L+ R+ PE+ R+L+ GR Sbjct: 170 GWIAVGVGATIAALLVTG---LPSVGWRLAFGIAAIMAVAALVFRIRAPETVRFLVKKGR 226 Query: 349 PEEAHKIVADIETSVLGHE--QPSADFEKIRLRMRDHTPLREVAVTLFSTYRQRSLVGLT 406 EA IV +E + + Q + + I + P +A +F+ + L+GL Sbjct: 227 INEAESIVRIMEETAMKRARVQSLPEPKIINYSYQTTNPFSILAKRVFA----KRLIGLI 282 Query: 407 LMAAQAFFYNAIFFTFALILTDFFGVAASNVGWYIL 442 L +F F T F G + + + ++L Sbjct: 283 LFWFFIYFVQYTFSTLWDYYGKFIGYSGTMLNQFVL 318