BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0106.0009.p (361 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0512 [S] COG3391 Uncharacterized conserved protein Mac Methano... 87 5e-17 MA1591 [S] COG3391 Uncharacterized conserved protein Mac Methano... 86 1e-16 MA1904_1 [S] COG3391 Uncharacterized conserved protein Mac Metha... 84 6e-16 MA3120 [S] COG3391 Uncharacterized conserved protein Mac Methano... 81 3e-15 MA4033 [S] COG3391 Uncharacterized conserved protein Mac Methano... 79 1e-14 >MA0512 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 461 Score = 87.4 bits (215), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 86/318 (27%), Positives = 133/318 (41%), Gaps = 65/318 (20%) Query: 87 NKIYVIDLKATPPKLAATIAGGKQPSGLSFSPDGKMALVANRGDSSISVLSVNGTDVKIT 146 N I VID ++ AT+ G+ P+G++ SPDGK V N D ++S+++ T K+ Sbjct: 76 NNISVIDTATN--RVTATVGVGEHPAGVTVSPDGKKVYVVNSYDDTVSIINTT-TKNKVI 132 Query: 147 DTISMPDSVAHVAFAPDGKHALVARFPGHKISVLDIAGDKVTYAKIDLPAGQWPYNVAVT 206 T+ + +A +PDG A V F + +SV+D +KVT + G +P +AV+ Sbjct: 133 TTVKVGTYPQEIAVSPDGTKAYVTSFSNNIVSVIDTTTNKVTAT---VKVGNFPLGIAVS 189 Query: 207 PNSKIALTSDNGNSGASDGSVDTASVID-------------------------------- 234 P+ K +++G G S T SVID Sbjct: 190 PDGKKVYVANSG--GDSTNFTGTVSVIDTTTNTVAATIPTGNNSLRVAVSPDGTKAYVMN 247 Query: 235 -------------LEAKPPRIIDRVVVGDGPEGLGVSPKGDLAVSVILRGSNMKNAFFHE 281 ++ + D V +GD P G+ VSP G I SN Sbjct: 248 SNIYRDSTAAIYVIDISTNEVTDVVNIGDIPCGVAVSPDGKKVYVSIQYLSN-------S 300 Query: 282 KNGSVSVLKIDGKKVTKTGDIEVGGLPEAAVFTPDGKYILVGNYLSQDFSILKVDGTNVT 341 G+V+++ KV T + VG P + TPDG + V N S S++ + VT Sbjct: 301 LTGAVNIIDTATNKVKAT--VSVGKAPSGIIVTPDGTKVYVVNCASHTVSVIDTATSRVT 358 Query: 342 DTGKRFQVPGHPASAGMG 359 DT +V +PA +G Sbjct: 359 DT---VKVGIYPARVAIG 373 >MA1591 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 443 Score = 85.9 bits (211), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 87/304 (28%), Positives = 131/304 (43%), Gaps = 58/304 (19%) Query: 87 NKIYVIDLKATPPKLAATIAGGKQPSGLSFSPDGKMALVANRGDSSISVLSVNGTDVKIT 146 N + VID K+ AT+ G+ P+G++ SPDG A V N D ++S+ ++ T K+ Sbjct: 65 NNLSVIDTATN--KVTATVDVGEHPAGVTVSPDGTKAYVVNSYDDTVSI--IDTTKNKVI 120 Query: 147 DTISMPDSVAHVAFAPDGKHALVARFPGHKISVLDIAGDKVTYAKIDLPAGQWPYNVAVT 206 T+ + ++A +PDG A V F + +SV++ +KVT +P G +P+ VAV+ Sbjct: 121 ATVKVGTYPQNIAVSPDGTKAYVTSFSNNTVSVINTTINKVTAT---VPVGNFPFGVAVS 177 Query: 207 PNSKIALTSDNGNSGASDGSVDTASVIDLE-----------------AKPP--------- 240 P+ K +++G G S T SVID A P Sbjct: 178 PDGKKVYVANSG--GYSTNFTGTVSVIDTTANTAAATIPTGNNSLGVAISPDGKKVYVAN 235 Query: 241 --------------RIIDRVVVGDGPEGLGVSPKGDLAVSVILRGSNMKNAFFHEKNGSV 286 ++ V G P+G+ VSP G I N N+ G+V Sbjct: 236 MAGSSISIIDTISNAVVSTVKTGRSPKGVAVSPDGKK----IYVAINPINSL----TGAV 287 Query: 287 SVLKIDGKKVTKTGDIEVGGLPEAAVFTPDGKYILVGNYLSQDFSILKVDGTNVTDTGKR 346 ++ KVT T + VG P TPDG + V NY S S++ VTDT K Sbjct: 288 DIIDTATNKVTATA-VPVGKAPGGIEVTPDGAKVYVVNYASHTVSVIDTATNKVTDTVKV 346 Query: 347 FQVP 350 + P Sbjct: 347 GKYP 350 >MA1904_1 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 361 Score = 83.6 bits (205), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 93/315 (29%), Positives = 143/315 (45%), Gaps = 48/315 (15%) Query: 30 VDLADPENPKIAASLPLKNSVVGPPVNVAIDPTGTVALVADSVDVVKEGDALKQVPDNKI 89 + + D K+AA++P+ ++ PV VAI+P GT VA+ N + Sbjct: 80 ISVIDVSTNKVAATIPVGSN----PVGVAINPDGTKVYVAND-------------HSNDV 122 Query: 90 YVIDLKATPPKLAATIAGGKQPSGLSFSPDGKMALVANRGDSSISVLSVNGTDVKITDTI 149 VID + AT+ G P G++ SPDGK VAN +SISV+ + T + T+ Sbjct: 123 SVIDTATN--AVTATVPAGSSPQGIAVSPDGKTIYVANLAGNSISVI--DTTSNTVVSTV 178 Query: 150 SMPDSVAHVAFAPDGKHALVARFPGHKISVLDIAGDKVTYAKIDLPAGQWPYNVAVTPN- 208 + VA +PDGK V +S++D A KV + + + G+ P +AVTP+ Sbjct: 179 KTGRNPTGVAVSPDGKKVYVTNSEDKTVSIIDTA-TKVVISTVSV--GKDPREIAVTPDG 235 Query: 209 SKIALTSDNGNSGASDGSVDTASVIDLEAKPPRIIDRVVVGDGPEGLGVSPKGDLAVSVI 268 +K+ + N +SG T SVID+ + D V V P G+ V+P Sbjct: 236 AKVYVA--NSDSG-------TVSVIDVSTN--SVTDTVKVEGAPFGVAVTPD-------- 276 Query: 269 LRGSNMKNAFFHEKNGSVSVLKIDGKKVTKTGDIEVGGLPEAAVFTPDGKYILVGNYLSQ 328 G+ + + + +V+V+ + KVT T I VG P TPDG + V L Sbjct: 277 --GAKVYVTNYDQYFSTVAVIDVATNKVTAT--IPVGPDPVGVAVTPDGTKVYVAINLCN 332 Query: 329 DFSILKVDGTNVTDT 343 S++ VT T Sbjct: 333 TVSVIDTATNTVTAT 347 Score = 66.6 bits (161), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 108/241 (44%), Gaps = 34/241 (14%) Query: 122 MALVANRGDSSISVLSVNGTDVKITDTISMPDSVAHVAFAPDGKHALVARFPGHKISVLD 181 A + N +SISV+ V+ K+ TI + + VA PDG VA + +SV+D Sbjct: 69 FAYITNEESNSISVIDVSTN--KVAATIPVGSNPVGVAINPDGTKVYVANDHSNDVSVID 126 Query: 182 IAGDKVTYAKIDLPAGQWPYNVAVTPNSK-IALTSDNGNSGASDGSVDTASVIDLEAKPP 240 A + VT +PAG P +AV+P+ K I + + GNS SVID + Sbjct: 127 TATNAVTAT---VPAGSSPQGIAVSPDGKTIYVANLAGNS---------ISVIDTTSN-- 172 Query: 241 RIIDRVVVGDGPEGLGVSPKGDLAVSVILRGSNMKNAFFHEKNGSVSVLKIDGKKVTKTG 300 ++ V G P G+ VSP G K + ++ +VS++ K V T Sbjct: 173 TVVSTVKTGRNPTGVAVSPDGK------------KVYVTNSEDKTVSIIDTATKVVIST- 219 Query: 301 DIEVGGLPEAAVFTPDGKYILVGNYLSQDFSILKVDGTNVTDTGKRFQVPGHPASAGMGP 360 + VG P TPDG + V N S S++ V +VTDT K V G P + P Sbjct: 220 -VSVGKDPREIAVTPDGAKVYVANSDSGTVSVIDVSTNSVTDTVK---VEGAPFGVAVTP 275 Query: 361 N 361 + Sbjct: 276 D 276 >MA3120 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 487 Score = 81.3 bits (199), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 88/316 (27%), Positives = 132/316 (41%), Gaps = 51/316 (16%) Query: 18 VLSAPGKDQVLIVDLADPENPKIAASLPLKNSVVGPPVNVAIDPTGTVALVADSVDVVKE 77 V+ +P V ++D A K++A + L +S P + +P GT V Sbjct: 111 VVDSPSDSTVYVIDTATN---KVSAKVNLGSSY---PARITFNPAGTRVYVT-------- 156 Query: 78 GDALKQVPDNKIYVIDLKATPPKLAATIAGGKQPSGLSFSPDGKMALVANRGDSSISVLS 137 KQ I+VI+ L A I G G++F+PDGK AN +++I V Sbjct: 157 ----KQHDYTDIFVINPATN--TLMAPIIVGPSTYGIAFTPDGKKIYAANCNNNTIYV-- 208 Query: 138 VNGTDVKITDTISMPDSVAHVAFAPDGKHALVARFPGHKISVLDIAGDKVTYAKIDLPAG 197 ++ K+T IS+ DS +A PDGK V + + +SV++ A D V +P G Sbjct: 209 IDAATNKVTANISVGDSPCGIAVTPDGKKVYVLNYDSNTVSVINTATDNVIAT---VPVG 265 Query: 198 QWPYNVAVTPNSKIALTSDNGNSGASDGSVDTASVIDLEAKPPRIIDRVVVGDGPEGLGV 257 P VAVT N ++N +T SVID +I + VG + + Sbjct: 266 NSPNLVAVTSNGNKVYVANN----------NTVSVIDTATN--NVIATIPVGTSSRKIVI 313 Query: 258 SPKGDLAVSVILRGSNMKNAFFHEKNGSVSVLKIDGKKVTKTGDIEVGGLPEAAVFTPDG 317 +P G N + GS SV ID ++ VG P TPDG Sbjct: 314 NPDG--------------NRVYLVNFGSNSVSVIDTATDNVIANVPVGEQPMGIAVTPDG 359 Query: 318 KYILVGNYLSQDFSIL 333 K + V N S + S++ Sbjct: 360 KRVYVTNSRSSNVSVI 375 >MA4033 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 456 Score = 79.3 bits (194), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 80/265 (30%), Positives = 124/265 (46%), Gaps = 44/265 (16%) Query: 88 KIYVIDLKATPPKLA----------ATIAGGKQPSGLSFSPDGKMALVANR------GDS 131 K+YV D+ ++ A + G P G++ +P G V NR + Sbjct: 80 KVYVTDISGLSTTVSVIDTATNTVDAVVDVGGYPRGVAVNPTGSRVYVTNRYSRVEDNSN 139 Query: 132 SISVL-SVNGTDVK-ITDTISMPDSVAHVAFAPDGKHALVARFPGHKISVLDIAGDKVTY 189 ++SV+ +V GT + D ++M S +VAF PDG+ + SVLD A +KVT Sbjct: 140 NVSVINTVIGTSTNTVMDPVNMGLSTYNVAFTPDGEKIYATNSRNNTTSVLDAATNKVTA 199 Query: 190 AKIDLPAGQWPYNVAVTPN-SKIALTSDNGNSGASDGSVDTASVIDLEAKPPRIIDRVVV 248 +P G +P +VA++P+ +K+ + NSG+++ SVID + V V Sbjct: 200 T---VPVGDYPTDVAISPDGNKVYVI----NSGSNN-----VSVIDTNTN--NVTGTVPV 245 Query: 249 GDGPEGLGVSPKGDLAVSVILRGSNMKNAFFHEKNGSVSVLKIDGKKVTKTGDIEVGGLP 308 GDGP + VSP G + V GS E +VSV+ VT T + +G P Sbjct: 246 GDGPSDIAVSPDG-TKIYVTNSGS------LDEPGNTVSVINTATNSVTAT--VSIGTAP 296 Query: 309 EAAVFTPDGK--YILVGNYLSQDFS 331 TPDGK Y++V + S D++ Sbjct: 297 RGVAVTPDGKKAYVVVSDIHSSDYT 321 Score = 65.5 bits (158), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 120/251 (47%), Gaps = 27/251 (10%) Query: 52 GPPVNVAIDPTGTVALVADSVDVVKEGDALKQVPDNKIYVID--LKATPPKLAATIAGGK 109 G P VA++PTG+ V + V++ N + VI+ + + + + G Sbjct: 111 GYPRGVAVNPTGSRVYVTNRYSRVEDN-------SNNVSVINTVIGTSTNTVMDPVNMGL 163 Query: 110 QPSGLSFSPDGKMALVANRGDSSISVLSVNGTDVKITDTISMPDSVAHVAFAPDGKHALV 169 ++F+PDG+ N +++ SVL + K+T T+ + D VA +PDG V Sbjct: 164 STYNVAFTPDGEKIYATNSRNNTTSVL--DAATNKVTATVPVGDYPTDVAISPDGNKVYV 221 Query: 170 ARFPGHKISVLDIAGDKVTYAKIDLPAGQWPYNVAVTPN-SKIALTSDNGNSGASDGSVD 228 + +SV+D + VT +P G P ++AV+P+ +KI +T NSG+ D + Sbjct: 222 INSGSNNVSVIDTNTNNVTGT---VPVGDGPSDIAVSPDGTKIYVT----NSGSLDEPGN 274 Query: 229 TASVIDLEAKPPRIIDRVVVGDGPEGLGVSPKGDLAVSVILRGSNMKNAFFHEKNGSVSV 288 T SVI+ + V +G P G+ V+P G A V+ S++ ++ + + VSV Sbjct: 275 TVSVINTATN--SVTATVSIGTAPRGVAVTPDGKKAYVVV---SDIHSSDYTDN---VSV 326 Query: 289 LKIDGKKVTKT 299 + KVT T Sbjct: 327 IDTTTNKVTAT 337 Score = 61.6 bits (148), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 52/171 (30%), Positives = 83/171 (48%), Gaps = 11/171 (6%) Query: 48 NSVVGPPVNVAIDPTGTVALVADSVDVVKEGDALKQVPDNKIYVIDLKATPPKLAATIAG 107 N+V+G N +DP + L +V +G+ + L A K+ AT+ Sbjct: 145 NTVIGTSTNTVMDPVN-MGLSTYNVAFTPDGEKIYATNSRNNTTSVLDAATNKVTATVPV 203 Query: 108 GKQPSGLSFSPDGKMALVANRGDSSISVLSVNGTDVKITDTISMPDSVAHVAFAPDGKHA 167 G P+ ++ SPDG V N G +++SV+ N +V T T+ + D + +A +PDG Sbjct: 204 GDYPTDVAISPDGNKVYVINSGSNNVSVIDTNTNNV--TGTVPVGDGPSDIAVSPDGTKI 261 Query: 168 LVARF-----PGHKISVLDIAGDKVTYAKIDLPAGQWPYNVAVTPNSKIAL 213 V PG+ +SV++ A + VT A + + G P VAVTP+ K A Sbjct: 262 YVTNSGSLDEPGNTVSVINTATNSVT-ATVSI--GTAPRGVAVTPDGKKAY 309