BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0106.0008.p (1157 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5691_1 [ER] COG0591 Na+/proline symporter Mlo Mesorhizobium loti 531 e-150 SMc02249_1 [ER] COG0591 Na+/proline symporter Sme Sinorhizobium ... 520 e-147 AGc932_1 [ER] COG0591 Na+/proline symporter Atu Agrobacterium tu... 515 e-145 BMEI1606_1 [ER] COG0591 Na+/proline symporter Bme Brucella melit... 505 e-142 PA3271_1 [ER] COG0591 Na+/proline symporter Pae Pseudomonas aeru... 414 e-115 >mll5691_1 [ER] COG0591 Na+/proline symporter Mlo Mesorhizobium loti Length = 604 Score = 531 bits (1368), Expect = e-150, Method: Compositional matrix adjust. Identities = 291/604 (48%), Positives = 404/604 (66%), Gaps = 23/604 (3%) Query: 7 VIATAFAYIGLLFFIASRGDRTSP-GERGRASQWIYPLSLAIYCTSWTFFGSVGFATRTS 65 ++ A AY+ LLF IAS GDR S GRA +IY LSLAIYCTSWTFFGSVG ++ Sbjct: 6 IVIIAIAYVTLLFAIASLGDRRSAVSGPGRARPFIYALSLAIYCTSWTFFGSVGLSSERG 65 Query: 66 IDFLAIYVGPIVMVGLCTPLLRRVIALAKSQNITSIADFIAARYGKSQAVAATVALIAII 125 ++FL IY GP+++ PLL R++ LAK++ ITSIADF+ ARYGKS VAA LIA I Sbjct: 66 LEFLGIYTGPVLVFVFGFPLLNRIVRLAKTEKITSIADFLGARYGKSFTVAAIATLIATI 125 Query: 126 GSVPYIALQLKAVAASLETILSEDQAF--SKIPVIGDIALMVTLAMAVFAVLFGTRHTDA 183 G+VPYIALQLKA++ S+ ++ S P + DI+L+V + +A+FAVLFGTRH DA Sbjct: 126 GAVPYIALQLKAISGSVSLMVEHYTGSPPSFDPFVSDISLVVAMLLALFAVLFGTRHADA 185 Query: 184 TEHQHGLILAIAAESIVKLVAFIAAGAFVTFWMF-SPVELYERALKTPEAARAIEYVPSI 242 TEHQ GL+LA+A E++VKL AF+A G VTF +F P +++ + + + +A+ Y S+ Sbjct: 186 TEHQDGLVLAVAVETVVKLAAFLAIGLMVTFLIFGGPGDMFAKLAENAQVRQAMGYNTSL 245 Query: 243 GNFLIMTLLSFCAVMLLPRQFHVSVVENSTPAEVTRARWLFPLYLIAINLFVIPIAIAGL 302 +L++T LS A+++LPRQF+V++VEN AE+ A W+FPLYL+AINLFV+PIA AGL Sbjct: 246 ATWLVLTCLSGFAIIMLPRQFYVTIVENRGEAELRTATWVFPLYLVAINLFVLPIAFAGL 305 Query: 303 VIFPFGAVDADMFVLALPIEGNSQLLSLAVFVGGLSAATAMVIVECVALSIMVSNDIVLP 362 + G +D++VL+LP+ LL++A F+GGLSAATAMVIVE VALSIM+SND+V+P Sbjct: 306 SLVGTGT-SSDLYVLSLPLFSGHDLLAMAAFIGGLSAATAMVIVESVALSIMISNDLVIP 364 Query: 363 LVLPR-SDDARAGQKDFGDFLLKARRFSIFAIMVLAYFYYRALGNT-QLVAIGLLSFAAI 420 L + R + + +D+ +L RR +IF ++ +A+ YYR N+ +L +IGL+SFAAI Sbjct: 365 LFVRRLLKTSTSENEDWSTLILNVRRGAIFILLFIAFLYYRESTNSARLSSIGLMSFAAI 424 Query: 421 TQLAPAFFGGLFWRRATARGAMAGMLVGFATWLYTLFIPSFLETSTAGLMLLQHGPFGVE 480 Q APA GGL WR A RGA GM+ G W YTL +PS + T ++ HG FG E Sbjct: 425 AQFAPALIGGLIWRGANGRGAALGMVAGILVWSYTLLLPSLVAPDTD---IVVHGLFGFE 481 Query: 481 ALRPX------------GVLWSLALNILTYVLFSLARAPSSIELLQADVFVPNALAPIAP 528 ALRP GVLWSL++N L +VL SL+RA +E +QA +FVP P+ P Sbjct: 482 ALRPQALFGTVAEPLNHGVLWSLSINTLFFVLGSLSRASVPLERIQASIFVPRDAGPM-P 540 Query: 529 SFRRWRTTVTVEDIQSTVTQYLGPDRTREAFASFAVDRNIVLLASAPADFELLQHAERLI 588 S RR+RT +TV D++ T+ +YLG +RT +F SF L A ++++ +E+L+ Sbjct: 541 SLRRFRTAITVNDLKDTIARYLGVERTERSFQSFEKTNGASLHGKEQASMDVIRFSEQLL 600 Query: 589 ASSI 592 AS++ Sbjct: 601 ASAV 604 >SMc02249_1 [ER] COG0591 Na+/proline symporter Sme Sinorhizobium meliloti Length = 626 Score = 520 bits (1340), Expect = e-147, Method: Compositional matrix adjust. Identities = 294/624 (47%), Positives = 411/624 (65%), Gaps = 21/624 (3%) Query: 1 MLHDWGVIATAFAYIGLLFFIASRGDR----TSPGERGRASQWIYPLSLAIYCTSWTFFG 56 ML + A+AFAY+ LLF +AS GDR +GR +Y LSLAIYCTSWT+FG Sbjct: 1 MLSGSVIFASAFAYLLLLFAVASYGDRRARRNEIAAKGR--PLVYALSLAIYCTSWTYFG 58 Query: 57 SVGFATRTSIDFLAIYVGPIVMVGLCTPLLRRVIALAKSQNITSIADFIAARYGKSQAVA 116 VG A ++F IY+GPI+M L PL+RR++ LAK++ +TS+ADF+AARYGK+ AVA Sbjct: 59 GVGLAAERGLEFTGIYIGPILMFTLGMPLIRRIVRLAKTEKLTSVADFVAARYGKNPAVA 118 Query: 117 ATVALIAIIGSVPYIALQLKAVAASLETIL-SEDQAFSKIPVIGDIALMVTLAMAVFAVL 175 A VALI+++G++PYIALQLKAV++S+ T++ + D D+ L+VTL +A FA++ Sbjct: 119 AIVALISLVGAIPYIALQLKAVSSSVATMIDTSDYGIGSGENFVDLPLLVTLFLACFAIV 178 Query: 176 FGTRHTDATEHQHGLILAIAAESIVKLVAFIAAGAFVTFWMF-SPVELYERALKTPEAAR 234 FGTRHTDATEHQ GLILAIA ES+VKLVA + G ++ F +F P L+ A ++ Sbjct: 179 FGTRHTDATEHQDGLILAIAMESVVKLVAMLTVGVYIVFVLFGGPANLWAEAQQSVTVIA 238 Query: 235 AIEYVPSIGNFLIMTLLSFCAVMLLPRQFHVSVVENSTPAEVTRARWLFPLYLIAINLFV 294 A+EY + +++M LS +++LPRQFHV+VVEN T E+ A LFPLYLIAIN FV Sbjct: 239 ALEYQTPVARWILMIALSAFGIIMLPRQFHVTVVENRTDNELRTAGILFPLYLIAINAFV 298 Query: 295 IPIAIAGLVIFPFGAVDADMFVLALPIEGNSQLLSLAVFVGGLSAATAMVIVECVALSIM 354 +PIAIAG++ F G+ +AD+++LALP+ G+ L++L F+GG SAATAMVIV VALSIM Sbjct: 299 LPIAIAGILTFS-GSGNADLYLLALPLAGDVPLVTLFTFIGGFSAATAMVIVASVALSIM 357 Query: 355 VSNDIVLPLVLPRSDDARAG-QKDFGDFLLKARRFSIFAIMVLAYFYYRALG-NTQLVAI 412 VSNDIV+P+ L R R Q+D LL RR +IF ++ L Y YYRA + L ++ Sbjct: 358 VSNDIVMPVFLRRRLGTRGSLQEDMAGTLLNIRRTAIFVVLFLGYGYYRAADISAGLASL 417 Query: 413 GLLSFAAITQLAPAFFGGLFWRRATARGAMAGMLVGFATWLYTLFIPSF-------LETS 465 GLLSFAAI Q+APA GGL WR+A ARGA+AGM+ GF W Y LF+PS + ++ Sbjct: 418 GLLSFAAIAQMAPALLGGLVWRQANARGAIAGMVSGFLVWAYVLFLPSLGGPDNSHIAST 477 Query: 466 TAGLMLLQHGPFGVEALRPX--GVLWSLALNILTYVLFSLARAPSSIELLQADVFVPNAL 523 +L F P S+ +N+ Y++ SL RAP +E QA VF+ Sbjct: 478 VLSFLLPFTDLFSGAQSDPLVNATALSMLVNVAAYIVGSLTRAPKPLERFQAGVFITRR- 536 Query: 524 APIAPSFRRWRTTVTVEDIQSTVTQYLGPDRTREAFASFAVDRNIVLLASAPADFELLQH 583 + +FR +T VTV D+++T+ +Y+G +R + +F ++ L +A AD L+ Sbjct: 537 SRTERTFRGRKTKVTVRDLKTTIGRYMGEERMQRSFHTYEQQSGRWLDDNASADMALVHF 596 Query: 584 AERLIASSIGAASSRLVMSLLLQR 607 +E+L+ S+IG++S+RLV+SL+LQR Sbjct: 597 SEQLLGSAIGSSSARLVLSLVLQR 620 >AGc932_1 [ER] COG0591 Na+/proline symporter Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 606 Score = 515 bits (1326), Expect = e-145, Method: Compositional matrix adjust. Identities = 298/609 (48%), Positives = 398/609 (65%), Gaps = 20/609 (3%) Query: 1 MLHDWGVIATAFAYIGLLFFIASRGDRTSPGERG--RASQWIYPLSLAIYCTSWTFFGSV 58 ML W + +AFAYI LLF +AS GDR S + ++Y LSLAIYCTSWT+FG V Sbjct: 1 MLPGWIIFGSAFAYILLLFAVASYGDRKSRDRHAPKKGRPFVYALSLAIYCTSWTYFGGV 60 Query: 59 GFATRTSIDFLAIYVGPIVMVGLCTPLLRRVIALAKSQNITSIADFIAARYGKSQAVAAT 118 G A ++FL IY GPI+ L P++RR++ LAK++ +TS+ADFIAARYGK+ VA Sbjct: 61 GLAADKGLEFLGIYTGPILAFTLGMPIIRRIVDLAKTEKLTSVADFIAARYGKNSTVAMI 120 Query: 119 VALIAIIGSVPYIALQLKAVAASLETILSE-DQAF-SKIPVIGDIALMVTLAMAVFAVLF 176 VA+IA++G++PYIALQLKAV++S+ T++ D S D+ L+VTL MA FAV+F Sbjct: 121 VAIIALVGAIPYIALQLKAVSSSVATMVDPGDYGIGSGNLYFLDLPLVVTLVMAGFAVMF 180 Query: 177 GTRHTDATEHQHGLILAIAAESIVKLVAFIAAGAFVTFWMF-SPVELYERALKTPEAARA 235 GTRHTDATEHQ GLILAI+ ES+VKLVA G +V F +F P L++ A +A RA Sbjct: 181 GTRHTDATEHQDGLILAISMESLVKLVAMCTVGFYVLFVLFDGPAHLWQLATDNEQAMRA 240 Query: 236 IEYVPSIGNFLIMTLLSFCAVMLLPRQFHVSVVENSTPAEVTRARWLFPLYLIAINLFVI 295 I Y I +++MTLLS A++LLPRQFHV+VVEN TP E+ A +L PLYLIAIN+FV+ Sbjct: 241 ISYHTPISRWIVMTLLSGFAIILLPRQFHVTVVENRTPEELRMAGFLLPLYLIAINIFVL 300 Query: 296 PIAIAGLVIFPFGAV-DADMFVLALPIEGNSQLLSLAVFVGGLSAATAMVIVECVALSIM 354 PIA+AG I GA DAD++VL LP+ ++SL F+GG SAATAMVIV VALSIM Sbjct: 301 PIALAG--ILTLGANGDADLYVLQLPLNHQMPVVSLITFIGGFSAATAMVIVASVALSIM 358 Query: 355 VSNDIVLPLVLPRSDDARAGQK-DFGDFLLKARRFSIFAIMVLAYFYYRALGN-TQLVAI 412 +SNDIV+P+ L + R+ + DF LL RR +IFA+M+L Y YYRA + T L +I Sbjct: 359 ISNDIVMPIFLRQKLLNRSPHRDDFAKTLLNIRRTAIFAVMLLGYGYYRAADSATGLASI 418 Query: 413 GLLSFAAITQLAPAFFGGLFWRRATARGAMAGMLVGFATWLYTLFIPSF-------LETS 465 GLL+FAAI Q+APA FGGLFWRRA ARGA+AG+ GF W Y LF+PSF + + Sbjct: 419 GLLAFAAIAQMAPALFGGLFWRRANARGAIAGLSSGFFVWAYLLFLPSFGGPDNSEVAAN 478 Query: 466 TAGLMLLQHGPFGVEALRP--XGVLWSLALNILTYVLFSLARAPSSIELLQADVFVPNAL 523 G + F P V+ SL +N L +VL SL+R P +E +Q+ +FV Sbjct: 479 ILGFLFSGSTVFNGPEADPFVNAVILSLLVNSLAFVLGSLSRNPRPVERIQSGIFVKRH- 537 Query: 524 APIAPSFRRWRTTVTVEDIQSTVTQYLGPDRTREAFASFAVDRNIVLLASAPADFELLQH 583 + + R W+T V+V D++S + +YLG +R + A++ L PAD L+ Sbjct: 538 SKSQFATRGWKTRVSVGDLKSAIARYLGEERMLRSLATYEKTAGRKLNDDQPADMALIHF 597 Query: 584 AERLIASSI 592 +E+L+ S+I Sbjct: 598 SEQLLGSAI 606 >BMEI1606_1 [ER] COG0591 Na+/proline symporter Bme Brucella melitensis Length = 603 Score = 505 bits (1300), Expect = e-142, Method: Compositional matrix adjust. Identities = 287/608 (47%), Positives = 393/608 (64%), Gaps = 22/608 (3%) Query: 2 LHDWGVIATAFAYIGLLFFIASRGDRTSPGERGRASQWIYPLSLAIYCTSWTFFGSVGFA 61 + WG+I AF Y+ LLF +AS GDR + +IY LSLA+YCTSWTFFGSVG + Sbjct: 1 MQGWGIIGFAFLYLLLLFAVASIGDRRTARWSSTPRPYIYALSLAVYCTSWTFFGSVGLS 60 Query: 62 TRTSIDFLAIYVGPIVMVGLCTPLLRRVIALAKSQNITSIADFIAARYGKSQAVAATVAL 121 + ++FL IY+GPI++ L LLR ++ LAKS++ITSIADF+AARYGKS VA+ Sbjct: 61 AQRGLEFLGIYIGPILVFTLGNRLLRHIVRLAKSEHITSIADFLAARYGKSFGVASLATC 120 Query: 122 IAIIGSVPYIALQLKAVAASLETILSEDQAF--SKIPVIGDIALMVTLAMAVFAVLFGTR 179 IA +GS+PYIALQLKAV+ S+ ++ A + V GDI+L V +A FA+LFGTR Sbjct: 121 IAAVGSIPYIALQLKAVSGSVGLVMDYYGAAVDPAVFVFGDISLPVAAVLATFAILFGTR 180 Query: 180 HTDATEHQHGLILAIAAESIVKLVAFIAAGAFVTFWMF-SPVELYERALKTPEAARAIEY 238 HTDATEHQ+GLILA+A ES++KL AF+ G F++F +P +L + ++PEA A Y Sbjct: 181 HTDATEHQNGLILAVALESVIKLCAFLTVGLACAFFLFGAPSQLIRQISQSPEALEAFHY 240 Query: 239 VPSIGNFLIMTLLSFCAVMLLPRQFHVSVVENSTPAEVTRARWLFPLYLIAINLFVIPIA 298 SIG +L+ T LS AV++LPRQFHV+VVE+ + E+ A WLFPLYLI IN+FV PIA Sbjct: 241 ETSIGTWLVQTALSAAAVIMLPRQFHVTVVESRSEKELRTASWLFPLYLILINIFVFPIA 300 Query: 299 IAGLVIFPFGAVDADMFVLALPIEGNSQLLSLAVFVGGLSAATAMVIVECVALSIMVSND 358 + G++ +V+ D++VLALP+ + L+L F+GGLSAATAMVIV CVALSIM+SN Sbjct: 301 LIGVMTLG-NSVNGDLYVLALPLSAGAHWLALIAFLGGLSAATAMVIVACVALSIMISNH 359 Query: 359 IVLPLVLPR-SDDARAGQKDFGDFLLKARRFSIFAIMVLAYFYYRALGNT-QLVAIGLLS 416 +VLPL++ + A Q+ +L RR +I I+ LA+ YYR N L +IG +S Sbjct: 360 LVLPLIISSFAKRHLAEQRGLTKIILNTRRITIIVILALAFSYYRLTSNNIHLASIGFVS 419 Query: 417 FAAITQLAPAFFGGLFWRRATARGAMAGMLVGFATWLYTLFIPSFLETSTAGLMLLQHGP 476 FAA+ Q APA GGLFWR A RGAM G+ GF W YTL +P+ + A L+ G Sbjct: 420 FAAVAQFAPALIGGLFWRNANGRGAMLGLSAGFIVWCYTLLLPTVAPENAAS---LRDGF 476 Query: 477 FGVEALRP------------XGVLWSLALNILTYVLFSLARAPSSIELLQADVFVPNALA 524 G ALRP GV WS+A N L Y+L SL+RA + +E +QA +F+P Sbjct: 477 LGFTALRPEALFGTNALPLTNGVAWSIAANTLFYILGSLSRASTPLERIQASIFLPRTFI 536 Query: 525 PIAPSFRRWRTTVTVEDIQSTVTQYLGPDRTREAFASFAVDRNIVLLASAPADFELLQHA 584 AP+ +R+RTTVTV ++++T+ +YLG +R AF F L D L+++A Sbjct: 537 G-APTLKRFRTTVTVAELKATMARYLGAERVERAFLRFEGREQRRLDPGMTVDTPLIRYA 595 Query: 585 ERLIASSI 592 E+L+ +++ Sbjct: 596 EQLLGTAV 603 >PA3271_1 [ER] COG0591 Na+/proline symporter Pae Pseudomonas aeruginosa Length = 600 Score = 414 bits (1064), Expect = e-115, Method: Compositional matrix adjust. Identities = 258/600 (43%), Positives = 356/600 (59%), Gaps = 17/600 (2%) Query: 6 GVIAT-AFAYIGLLFFIASRGDRTSPGERGRASQWIYPLSLAIYCTSWTFFGSVGFATRT 64 G+IA A Y+ +LF IA GDR R W+Y LSLA+YCTSWTFFG+VG AT Sbjct: 6 GLIAVVALVYMAILFAIAFYGDRRRTPLSPRLRAWVYSLSLAVYCTSWTFFGAVGQATDQ 65 Query: 65 SIDFLAIYVGPIVMVGLCTPLLRRVIALAKSQNITSIADFIAARYGKSQAVAATVALIAI 124 FL IY+GP++++ +L+++I ++K +NITSIADFIAARYGKSQA+A VALI + Sbjct: 66 LWSFLPIYLGPVLLMLFAPWVLQKMIMISKQENITSIADFIAARYGKSQALAVVVALICM 125 Query: 125 IGSVPYIALQLKAVAASLETILSEDQAFSKIPVIGDIALMVTLAMAVFAVLFGTRHTDAT 184 +G +PYIALQLK + + ++ A S D AL+V+L +A+F ++FGTR D T Sbjct: 126 VGVLPYIALQLKGIVLGVNLLIGSG-ADSTGTRAQDTALIVSLVLALFTIVFGTRSLDVT 184 Query: 185 EHQHGLILAIAAESIVKLVAFIAAGAFVTFWMFSP-VELYERALKTPEAARAIEYVPSIG 243 EH G++LAIA ES+VKL AF+A G F TF ++ +L+ +A P+ A E Sbjct: 185 EHHRGMVLAIAFESLVKLTAFLAVGIFATFGLYDGFADLFSQARAAPQLADYWEETVHWP 244 Query: 244 NFLIMTLLSFCAVMLLPRQFHVSVVENSTPAEVTRARWLFPLYLIAINLFVIPIAIAGLV 303 L+ T ++ A+M LPRQFHV+VVEN P ++ ARW+FP+YL+ LFV+PIA+AG + Sbjct: 245 AMLLQTGVAMTAIMCLPRQFHVTVVENIEPRDLNLARWVFPIYLVLAALFVVPIALAGQL 304 Query: 304 IFPFGAVDADMFVLALPIEGNSQLLSLAVFVGGLSAATAMVIVECVALSIMVSNDIVLPL 363 P G V D FV++LP+ L+L F+GG SAAT MVIV VALS MVSND++LP Sbjct: 305 HLPAG-VMPDSFVISLPLAEAHPALALLAFIGGASAATGMVIVASVALSTMVSNDMLLPW 363 Query: 364 VLPRSD-DARAGQKDFGDFLLKARRFSIFAIMVLAYFYYRALGNT-QLVAIGLLSFAAIT 421 +L R + D + F +LL RR SI I++LAY YR LG++ L IG ++FAAI Sbjct: 364 LLRRREKDTERPFEAFRHWLLTVRRVSIAVILLLAYVAYRLLGSSASLATIGQIAFAAIA 423 Query: 422 QLAPAFFGGLFWRRATARGAMAGMLVGFATWLYTLFIPSFLE------TSTAGLMLLQHG 475 QL PA G L+W++A RG AG+ G W YTL +P + GL L Sbjct: 424 QLGPAMIGALYWKQANRRGVFAGLAAGSLLWAYTLVLPVVAKGLGWPLERIPGLTWLASN 483 Query: 476 PFG--VEALRPXGVLWSLALNILTYVLFSLARAPSSIELLQADVFVPNALAPIAPSFRRW 533 PFG +E L GVL SL N + L S+ E QA F+ ++ S R+ Sbjct: 484 PFGLPIEPLT-QGVLISLVGNFALFGLVSVLSRTRVSEHWQASRFIGQEISQRQNS--RF 540 Query: 534 RTTVTVEDIQSTVTQYLGPDRTREAFASFAVDRNIVLLASAPADFELLQHAERLIASSIG 593 V VED+ +++G +R R++F FA + + A+ E + H ERL+A +G Sbjct: 541 MLAVQVEDLLMLAARFVGEERARQSFIRFAYRQGKGFTPNQTANNEWIAHTERLLAGVLG 600