BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0105.0006.p (563 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3234 [R] COG4147 Predicted symporter Pae Pseudomonas aeruginosa 716 0.0 yjcG [R] COG4147 Predicted symporter Eco Escherichia coli K12 707 0.0 ZyjcG [R] COG4147 Predicted symporter EcZ Escherichia coli O157:... 707 0.0 ECs5049 [R] COG4147 Predicted symporter Ecs Escherichia coli O15... 707 0.0 STM4273 [R] COG4147 Predicted symporter Sty Salmonella typhimuri... 701 0.0 >PA3234 [R] COG4147 Predicted symporter Pae Pseudomonas aeruginosa Length = 551 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/534 (68%), Positives = 436/534 (81%), Gaps = 11/534 (2%) Query: 30 KQAVNWAAIGMFIGFVSLTLAITYWASKRTVSAADFYSAGGGISAGQNGLAIAGDYMSAA 89 +Q +N +AI MF+ FV TL ITYWASKR SAAD+Y+AGG I+ QNGLAIAGDYMSAA Sbjct: 29 RQPLNVSAIVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAA 88 Query: 90 SFLGISGLVYTSGYDGLIYSVGWLVGWPVVTFLIAEQLRNLGKFTFADVASFRLGQTRIR 149 SFLGIS LV+TSGYDGLIYS+G+LVGWP++ FLIAE+LRNLGK+TFADVAS+RL Q +IR Sbjct: 89 SFLGISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLKQKQIR 148 Query: 150 ILAACGSLVTVAFYLIAQMVGAGKLIQLLFGLDYWIAVILVGGLMMIYVTFGGMKATTWV 209 L+ACGSLV VAFYLIAQMVGAGKLI+LLFGL+Y +AV+LVG LM++YV FGGM ATTWV Sbjct: 149 TLSACGSLVVVAFYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLATTWV 208 Query: 210 QIIKAVLLLFGATFMAGAVLYKFGFSPEALFAKATEVHPKKLAIMEPGSLISNPLSAISL 269 QIIKAVLLL GA+FMA VL F LF++A +VHPK AIM PG L+ +P+SA SL Sbjct: 209 QIIKAVLLLSGASFMAIMVLKHVNFDVSTLFSEAIKVHPKGEAIMSPGGLVKDPISAFSL 268 Query: 270 GLALMFGTAGLPHILMRFFTVKDAQAARKSVFYATGFIGYFYILTFIIGFGAITLVSTDL 329 G ALMFGTAGLPHILMRFFTV DA+ ARKSVFYATGFIGYFYILTFIIGFGAI LVST+ Sbjct: 269 GFALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLVSTNP 328 Query: 330 AFLDAGILEKTKSGIAAIKGGSNMAAIHLADAVGGNLFLGFISAVAFATILAVVSGLALA 389 F DA A+ GG+NMAA+HLADAVGG+LFLGFISAVAFATILAVV+GL LA Sbjct: 329 DFKDA---------TGALIGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLA 379 Query: 390 GASSISHDIYAMVIKGGRANEQDEVRVSKIATLFLGVLAIVLGIIFENQNVAFMVGLAFA 449 GAS++SHD+YA V KGG+ANE+DE+RVSK+ T+ LGV+AIVLGI+FE QN+AFMVGLAF+ Sbjct: 380 GASAVSHDLYASVFKGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFS 439 Query: 450 IAASCNFPVLVMSIFWKNLTTRGALIGGLLGLISAVVGVILSPAVWEVTLGFAKGSAPIK 509 IAASCNFPVL++S++WK LTTRGA+IGG +GLI+AV ++L P +W LG K P Sbjct: 440 IAASCNFPVLLLSMYWKKLTTRGAMIGGWMGLITAVGLMVLGPTIWVQILGHEKAIYP-- 497 Query: 510 LDNPALFSMAIAFASIWLISVLDRSARAGTDRDGFDAQFVRSQTGIGAASATSH 563 + PALFSM +AF IW S+ D+SA A +R F QF+RSQTG+GA+ A +H Sbjct: 498 YEYPALFSMIVAFVGIWFFSITDKSAAADEERARFFPQFIRSQTGLGASGAVAH 551 >yjcG [R] COG4147 Predicted symporter Eco Escherichia coli K12 Length = 549 Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/561 (65%), Positives = 437/561 (77%), Gaps = 13/561 (2%) Query: 4 MPHLLVTLFVCLPSIALAAGTIDGG-TKQAVNWAAIGMFIGFVSLTLAITYWASKRTVSA 62 M +L L LP A AA I G +Q NW AI MF+ FV TL ITYWASKR S Sbjct: 1 MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSR 60 Query: 63 ADFYSAGGGISAGQNGLAIAGDYMSAASFLGISGLVYTSGYDGLIYSVGWLVGWPVVTFL 122 +D+Y+AGG I+ QNGLAIAGDYMSAASFLGIS LV+TSGYDGLIYS+G+LVGWP++ FL Sbjct: 61 SDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFL 120 Query: 123 IAEQLRNLGKFTFADVASFRLGQTRIRILAACGSLVTVAFYLIAQMVGAGKLIQLLFGLD 182 IAE+LRNLG++TFADVAS+RL Q IRIL+ACGSLV VA YLIAQMVGAGKLI+LLFGL+ Sbjct: 121 IAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLN 180 Query: 183 YWIAVILVGGLMMIYVTFGGMKATTWVQIIKAVLLLFGATFMAGAVLYKFGFSPEALFAK 242 Y IAV+LVG LMM+YV FGGM ATTWVQIIKAVLLLFGA+FMA V+ GFS LF++ Sbjct: 181 YHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE 240 Query: 243 ATEVHPKKLAIMEPGSLISNPLSAISLGLALMFGTAGLPHILMRFFTVKDAQAARKSVFY 302 A VHPK + IM+PG L+ +P+SA+SLGL LMFGTAGLPHILMRFFTV DA+ ARKSVFY Sbjct: 241 AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFY 300 Query: 303 ATGFIGYFYILTFIIGFGAITLVSTDLAFLDAGILEKTKSGIAAIKGGSNMAAIHLADAV 362 ATGF+GYFYILTFIIGFGAI LV + + DA + GG+NMAA+HLA+AV Sbjct: 301 ATGFMGYFYILTFIIGFGAIMLVGANPEYKDAA---------GHLIGGNNMAAVHLANAV 351 Query: 363 GGNLFLGFISAVAFATILAVVSGLALAGASSISHDIYAMVIKGGRANEQDEVRVSKIATL 422 GGNLFLGFISAVAFATILAVV+GL LAGAS++SHD+YA V K G A E++E+RVSKI L Sbjct: 352 GGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKG-ATEREELRVSKITVL 410 Query: 423 FLGVLAIVLGIIFENQNVAFMVGLAFAIAASCNFPVLVMSIFWKNLTTRGALIGGLLGLI 482 LGV+AI+LG++FENQN+AFMVGLAFAIAASCNFP++++S++W LTTRGA++GG LGLI Sbjct: 411 ILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLI 470 Query: 483 SAVVGVILSPAVWEVTLGFAKGSAPIKLDNPALFSMAIAFASIWLISVLDRSARAGTDRD 542 +AVV +IL P +W LG K P + PALFS+ +AF IW S D SA +R+ Sbjct: 471 TAVVLMILGPTIWVQILGHEKAIFP--YEYPALFSITVAFLGIWFFSATDNSAEGARERE 528 Query: 543 GFDAQFVRSQTGIGAASATSH 563 F AQF+RSQTG G +H Sbjct: 529 LFRAQFIRSQTGFGVEQGRAH 549 >ZyjcG [R] COG4147 Predicted symporter EcZ Escherichia coli O157:H7 EDL933 Length = 549 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/561 (65%), Positives = 436/561 (77%), Gaps = 13/561 (2%) Query: 4 MPHLLVTLFVCLPSIALAAGTIDGG-TKQAVNWAAIGMFIGFVSLTLAITYWASKRTVSA 62 M +L L LP A AA I G +Q NW AI MF+ FV TL ITYWASKR S Sbjct: 1 MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSR 60 Query: 63 ADFYSAGGGISAGQNGLAIAGDYMSAASFLGISGLVYTSGYDGLIYSVGWLVGWPVVTFL 122 D+Y+AGG I+ QNGLAIAGDYMSAASFLGIS LV+TSGYDGLIYS+G+LVGWP++ FL Sbjct: 61 NDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFL 120 Query: 123 IAEQLRNLGKFTFADVASFRLGQTRIRILAACGSLVTVAFYLIAQMVGAGKLIQLLFGLD 182 IAE+LRNLG++TFADVAS+RL Q IRIL+ACGSLV VA YLIAQMVGAGKLI+LLFGL+ Sbjct: 121 IAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLN 180 Query: 183 YWIAVILVGGLMMIYVTFGGMKATTWVQIIKAVLLLFGATFMAGAVLYKFGFSPEALFAK 242 Y IAV+LVG LMM+YV FGGM ATTWVQIIKAVLLLFGA+FMA V+ GFS LF++ Sbjct: 181 YHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE 240 Query: 243 ATEVHPKKLAIMEPGSLISNPLSAISLGLALMFGTAGLPHILMRFFTVKDAQAARKSVFY 302 A VHPK + IM+PG L+ +P+SA+SLGL LMFGTAGLPHILMRFFTV DA+ ARKSVFY Sbjct: 241 AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFY 300 Query: 303 ATGFIGYFYILTFIIGFGAITLVSTDLAFLDAGILEKTKSGIAAIKGGSNMAAIHLADAV 362 ATGF+GYFYILTFIIGFGAI LV + + DA + GG+NMAA+HLA+AV Sbjct: 301 ATGFMGYFYILTFIIGFGAIMLVGANPEYKDAA---------GHLIGGNNMAAVHLANAV 351 Query: 363 GGNLFLGFISAVAFATILAVVSGLALAGASSISHDIYAMVIKGGRANEQDEVRVSKIATL 422 GGNLFLGFISAVAFATILAVV+GL LAGAS++SHD+YA V K G A E++E+RVSKI L Sbjct: 352 GGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKG-ATEREELRVSKITVL 410 Query: 423 FLGVLAIVLGIIFENQNVAFMVGLAFAIAASCNFPVLVMSIFWKNLTTRGALIGGLLGLI 482 LGV+AI+LG++FENQN+AFMVGLAFAIAASCNFP++++S++W LTTRGA++GG LGLI Sbjct: 411 ILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLI 470 Query: 483 SAVVGVILSPAVWEVTLGFAKGSAPIKLDNPALFSMAIAFASIWLISVLDRSARAGTDRD 542 +AVV +IL P +W LG K P + PALFS+ +AF IW S D SA +R+ Sbjct: 471 TAVVLMILGPTIWVQILGHEKAIFP--YEYPALFSITVAFLGIWFFSATDNSAEGARERE 528 Query: 543 GFDAQFVRSQTGIGAASATSH 563 F AQF+RSQTG G +H Sbjct: 529 LFRAQFIRSQTGFGVEQGRAH 549 >ECs5049 [R] COG4147 Predicted symporter Ecs Escherichia coli O157:H7 Length = 549 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/561 (65%), Positives = 436/561 (77%), Gaps = 13/561 (2%) Query: 4 MPHLLVTLFVCLPSIALAAGTIDGG-TKQAVNWAAIGMFIGFVSLTLAITYWASKRTVSA 62 M +L L LP A AA I G +Q NW AI MF+ FV TL ITYWASKR S Sbjct: 1 MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSR 60 Query: 63 ADFYSAGGGISAGQNGLAIAGDYMSAASFLGISGLVYTSGYDGLIYSVGWLVGWPVVTFL 122 D+Y+AGG I+ QNGLAIAGDYMSAASFLGIS LV+TSGYDGLIYS+G+LVGWP++ FL Sbjct: 61 NDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFL 120 Query: 123 IAEQLRNLGKFTFADVASFRLGQTRIRILAACGSLVTVAFYLIAQMVGAGKLIQLLFGLD 182 IAE+LRNLG++TFADVAS+RL Q IRIL+ACGSLV VA YLIAQMVGAGKLI+LLFGL+ Sbjct: 121 IAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLN 180 Query: 183 YWIAVILVGGLMMIYVTFGGMKATTWVQIIKAVLLLFGATFMAGAVLYKFGFSPEALFAK 242 Y IAV+LVG LMM+YV FGGM ATTWVQIIKAVLLLFGA+FMA V+ GFS LF++ Sbjct: 181 YHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE 240 Query: 243 ATEVHPKKLAIMEPGSLISNPLSAISLGLALMFGTAGLPHILMRFFTVKDAQAARKSVFY 302 A VHPK + IM+PG L+ +P+SA+SLGL LMFGTAGLPHILMRFFTV DA+ ARKSVFY Sbjct: 241 AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFY 300 Query: 303 ATGFIGYFYILTFIIGFGAITLVSTDLAFLDAGILEKTKSGIAAIKGGSNMAAIHLADAV 362 ATGF+GYFYILTFIIGFGAI LV + + DA + GG+NMAA+HLA+AV Sbjct: 301 ATGFMGYFYILTFIIGFGAIMLVGANPEYKDAA---------GHLIGGNNMAAVHLANAV 351 Query: 363 GGNLFLGFISAVAFATILAVVSGLALAGASSISHDIYAMVIKGGRANEQDEVRVSKIATL 422 GGNLFLGFISAVAFATILAVV+GL LAGAS++SHD+YA V K G A E++E+RVSKI L Sbjct: 352 GGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKG-ATEREELRVSKITVL 410 Query: 423 FLGVLAIVLGIIFENQNVAFMVGLAFAIAASCNFPVLVMSIFWKNLTTRGALIGGLLGLI 482 LGV+AI+LG++FENQN+AFMVGLAFAIAASCNFP++++S++W LTTRGA++GG LGLI Sbjct: 411 ILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLI 470 Query: 483 SAVVGVILSPAVWEVTLGFAKGSAPIKLDNPALFSMAIAFASIWLISVLDRSARAGTDRD 542 +AVV +IL P +W LG K P + PALFS+ +AF IW S D SA +R+ Sbjct: 471 TAVVLMILGPTIWVQILGHEKAIFP--YEYPALFSITVAFLGIWFFSATDNSAEGARERE 528 Query: 543 GFDAQFVRSQTGIGAASATSH 563 F AQF+RSQTG G +H Sbjct: 529 LFRAQFIRSQTGFGVEQGRAH 549 >STM4273 [R] COG4147 Predicted symporter Sty Salmonella typhimurium LT2 Length = 549 Score = 701 bits (1810), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/534 (67%), Positives = 427/534 (79%), Gaps = 12/534 (2%) Query: 30 KQAVNWAAIGMFIGFVSLTLAITYWASKRTVSAADFYSAGGGISAGQNGLAIAGDYMSAA 89 +Q NW AI MF+ FV TL ITYWASKR S +D+Y+AGG I+ QNGLAIAGDYMSAA Sbjct: 28 RQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAA 87 Query: 90 SFLGISGLVYTSGYDGLIYSVGWLVGWPVVTFLIAEQLRNLGKFTFADVASFRLGQTRIR 149 SFLGIS LV+TSGYDGLIYS+G+LVGWP++ FLIAE+LRNLG++TFADVAS+RL Q IR Sbjct: 88 SFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIR 147 Query: 150 ILAACGSLVTVAFYLIAQMVGAGKLIQLLFGLDYWIAVILVGGLMMIYVTFGGMKATTWV 209 IL+ACGSLV VA YLIAQMVGAGKLI+LLFGL+Y IAV+LVG LMM+YV FGGM ATTWV Sbjct: 148 ILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWV 207 Query: 210 QIIKAVLLLFGATFMAGAVLYKFGFSPEALFAKATEVHPKKLAIMEPGSLISNPLSAISL 269 QIIKAVLLLFGA+FMA V+ GFS LF +A VHPK AIM PG L+ +P+SA+SL Sbjct: 208 QIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSL 267 Query: 270 GLALMFGTAGLPHILMRFFTVKDAQAARKSVFYATGFIGYFYILTFIIGFGAITLVSTDL 329 GL LMFGTAGLPHILMRFFTV DA+ ARKSVFYATGF+GYFYILTFIIGFGAI LV + Sbjct: 268 GLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANP 327 Query: 330 AFLDAGILEKTKSGIAAIKGGSNMAAIHLADAVGGNLFLGFISAVAFATILAVVSGLALA 389 A+ DA A+ GG+NMAA+HLA+AVGGNLFLGFISAVAFATILAVV+GL LA Sbjct: 328 AYKDAA---------GALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLA 378 Query: 390 GASSISHDIYAMVIKGGRANEQDEVRVSKIATLFLGVLAIVLGIIFENQNVAFMVGLAFA 449 GAS++SHD+YA V + G A E++E++VSKI L LGV+AI+LG++FENQN+AFMVGLAFA Sbjct: 379 GASAVSHDLYANVFRKG-ATEREELKVSKITVLVLGVIAIILGVLFENQNIAFMVGLAFA 437 Query: 450 IAASCNFPVLVMSIFWKNLTTRGALIGGLLGLISAVVGVILSPAVWEVTLGFAKGSAPIK 509 IAASCNFP++++S++W LTTRGA++GG LGL++AVV +IL P +W LG K P Sbjct: 438 IAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFP-- 495 Query: 510 LDNPALFSMAIAFASIWLISVLDRSARAGTDRDGFDAQFVRSQTGIGAASATSH 563 + PALFS+++AF IW S D SA +R+ F AQF+RSQTG G +H Sbjct: 496 YEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH 549