BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0098.0021.p (178 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC3190 [V] COG1680 Beta-lactamase class C and other penicillin b... 95 1e-19 CC1568 [V] COG1680 Beta-lactamase class C and other penicillin b... 90 3e-18 CC3628 [V] COG1680 Beta-lactamase class C and other penicillin b... 84 2e-16 Rv1367c [V] COG1680 Beta-lactamase class C and other penicillin ... 83 3e-16 MT1414 [V] COG1680 Beta-lactamase class C and other penicillin b... 83 3e-16 >CC3190 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 490 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 66/186 (35%), Positives = 94/186 (50%), Gaps = 12/186 (6%) Query: 1 MNDTGYVL--GAETERTRLAEPLPSDTILIEGENDRRAH---PEWESGGGGLVSTILDYA 55 M DTG+ + G T PS ++++ + ++ + P +SGGGGLVST DY Sbjct: 303 MVDTGFFVPEGQRERFTACYALTPSGKVVLQDDPEKSRYLSDPSVKSGGGGLVSTADDYM 362 Query: 56 RFAQMLLNGGELDGKRYLSPAAFKTMTTDHIGPGSGVGRD----YWYFPGDGFGYGYGIA 111 RF +MLLNGGELDG R LSP K MT +HI G + + + +G G+G G A Sbjct: 363 RFCRMLLNGGELDGVRLLSPKTIKLMTMNHIPGGQELVQASKSLFSEAVFEGLGFGLGFA 422 Query: 112 VRTDPGIVKPPPPGSIGELKWDSGSGTYFGVDPKLDMIYIMLEQTQ-NERQRITPAFRKL 170 + D K GS+GE W + T F +DP D+ + + Q + I R L Sbjct: 423 MTIDQARTK--NLGSLGEYFWGGMASTAFWIDPVEDLAVVFMTQLMPSTSYPIRRELRTL 480 Query: 171 VYDAFS 176 VY +F+ Sbjct: 481 VYSSFT 486 >CC1568 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 436 Score = 89.7 bits (221), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/190 (36%), Positives = 92/190 (48%), Gaps = 22/190 (11%) Query: 1 MNDTGYVLGAETERTRLA----------EPLPSDTILIEGENDRRAHPEWESGGGGLVST 50 M DTG+ L AE + RLA + +P+D ++ D P SGGGGLVST Sbjct: 249 MKDTGFWLPAE-KADRLASLYVWSPKVNKLVPADGYMVL---DITKPPAMASGGGGLVST 304 Query: 51 ILDYARFAQMLLNGGELDGKRYLSPAAFKTMTTDHIGPGSGVGRDYWYFPGDGFGYGYGI 110 DYARFAQMLLNGGEL+G R L P M T+ + + + G G+G Sbjct: 305 NADYARFAQMLLNGGELEGARILKPETVTLMRTNALSDAIMTSSEPPFNTARGRGFGLDF 364 Query: 111 AVRTDPGIVKPPPPGSIGELKWDSGSGTYFGVDPKLDMIYIMLEQTQNER-----QRITP 165 A+ D K P G G W +GT+F +DPK D+ ++ + N+ + I Sbjct: 365 AIVLDSA--KAGPQGE-GTYSWGGAAGTWFWIDPKNDLFFLGMIHILNKAGDPAIKDIDD 421 Query: 166 AFRKLVYDAF 175 KLVYDA Sbjct: 422 DSAKLVYDAL 431 >CC3628 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 479 Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 51/131 (38%), Positives = 69/131 (52%), Gaps = 4/131 (3%) Query: 43 GGGGLVSTILDYARFAQMLLNGGELDGKRYLSPAAFKTMTTDHIGPGSGVGRDYWYFPGD 102 GG GLV++I DYARF++MLL G LDG R L P+ + M +DH+ P V W PG Sbjct: 342 GGAGLVASIDDYARFSRMLLGQGALDGVRILKPSTVRLMASDHLDP--RVTARSW-LPGK 398 Query: 103 G-FGYGYGIAVRTDPGIVKPPPPGSIGELKWDSGSGTYFGVDPKLDMIYIMLEQTQNERQ 161 G G+G+ +AVR G++GE WD + T F VDP + ++ QT Sbjct: 399 GAVGFGFDVAVRNSQPQTPSENRGAVGEYFWDGMASTVFWVDPANQLTAVLFVQTLPFDG 458 Query: 162 RITPAFRKLVY 172 + FR VY Sbjct: 459 TLHRDFRAAVY 469 >Rv1367c [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Mtu Mycobacterium tuberculosis H37Rv Length = 377 Score = 83.2 bits (204), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 58/170 (34%), Positives = 82/170 (48%), Gaps = 26/170 (15%) Query: 1 MNDTGYVLGAETERTRLAEPLPSDTILIEGENDRRAH----------PEWESGGGGLVST 50 M DTG+ + A+ +R + T+ E DR H P + + GGGL ST Sbjct: 180 MTDTGFYVSADAQRR-------AATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWST 232 Query: 51 ILDYARFAQMLLNGGELDGKRYLSPAAFKTMTTDHI----GPGSGVGRDYWYFPGDGFGY 106 DY RF +MLL G +DG R LSP + + M TD + S +G +W G G+ Sbjct: 233 ADDYLRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWV----GRGF 288 Query: 107 GYGIAVRTDPGIVKPP-PPGSIGELKWDSGSGTYFGVDPKLDMIYIMLEQ 155 G ++V TDP +P PG +G W GT++ DP D+I + L Q Sbjct: 289 GLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQ 338 >MT1414 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins MtC Mycobacterium tuberculosis CDC1551 Length = 401 Score = 83.2 bits (204), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 58/170 (34%), Positives = 82/170 (48%), Gaps = 26/170 (15%) Query: 1 MNDTGYVLGAETERTRLAEPLPSDTILIEGENDRRAH----------PEWESGGGGLVST 50 M DTG+ + A+ +R + T+ E DR H P + + GGGL ST Sbjct: 204 MTDTGFYVSADAQRR-------AATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWST 256 Query: 51 ILDYARFAQMLLNGGELDGKRYLSPAAFKTMTTDHI----GPGSGVGRDYWYFPGDGFGY 106 DY RF +MLL G +DG R LSP + + M TD + S +G +W G G+ Sbjct: 257 ADDYLRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWV----GRGF 312 Query: 107 GYGIAVRTDPGIVKPP-PPGSIGELKWDSGSGTYFGVDPKLDMIYIMLEQ 155 G ++V TDP +P PG +G W GT++ DP D+I + L Q Sbjct: 313 GLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQ 362