BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0098.0017.p (399 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll0051 [GEPR] COG0477 Permeases of the major facilitator superf... 341 2e-93 BMEI1130 [GEPR] COG0477 Permeases of the major facilitator super... 327 3e-89 AGc3403 [GEPR] COG0477 Permeases of the major facilitator superf... 309 9e-84 SMc00537 [GEPR] COG0477 Permeases of the major facilitator super... 308 2e-83 SMc00536 [GEPR] COG0477 Permeases of the major facilitator super... 299 7e-81 >mll0051 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 394 Score = 341 bits (875), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 192/386 (49%), Positives = 259/386 (67%) Query: 14 MALNPLAMDMMLPALPNIRSAFQIADANRPQMVLSIFLVGFGVGQFVMGPLSDRFGRRPV 73 MALN LA+D+MLPAL I ++ + + N Q V++ +++GFG GQ GP+SDRFGRR Sbjct: 1 MALNSLAIDIMLPALQQIGASLGVENENHRQYVVTAYILGFGGGQLFFGPISDRFGRRSP 60 Query: 74 LLGGMTVYTIAGLLAIMAPSFETLLLARALQGLGTAATRVIATSIVRDCYAGRRMASVMS 133 L+ G+ +Y A A +APSFETLL+ RA+QG+G AATRVIA SIVRD + GRRMA VMS Sbjct: 61 LVAGLIIYVAAAAAAAIAPSFETLLICRAVQGIGAAATRVIAVSIVRDTFEGRRMAEVMS 120 Query: 134 LAMMVFIAVPVIAPSFGQAVMLLTHWRGIFVLLMIYGVIALAWSAMRMPETLPRELRKSL 193 L MVF+A+PVIAP GQ +ML W IFV + + +I AWS +R+PETL E R+ L Sbjct: 121 LIFMVFMAIPVIAPGIGQFIMLFATWHYIFVTMAVGALIVSAWSLLRLPETLRPEYRRQL 180 Query: 194 AIPEVLSAFRQTVTNRQTLGYALAAGGVQGSLFAFVFSSQQIFTEIFKLGHYFPVAFAAC 253 + VL FR +TNR L YA A+ + ++F F+ S+QQI+ IF +G FPV FA Sbjct: 181 TVSSVLGGFRIVLTNRIALCYAFASTFIFAAMFGFIASAQQIYVGIFNVGEMFPVIFAGV 240 Query: 254 AVGVAIAGFLNSRIVGRIGMRVISHAALTGFAVVAGALFIAVKTDTLSLPLFMVLSGLMM 313 A +A + FLNSR+VGRIGMR +S +AL F V++ A + + L LF+ M Sbjct: 241 AGVLAFSNFLNSRLVGRIGMRRLSQSALLLFLVISLAWLVVSLEIKMPLWLFITFFASAM 300 Query: 314 FAFGLMMANFTALAMEPQGKIAGTASSLYGTITTLLGIGVGTTIGQDYDGTLLPFATGFF 373 FG + ANF ALAMEP G++AGTASS+ G + T LG +GT IGQ ++GT+ P A GF Sbjct: 301 LPFGALGANFNALAMEPLGQLAGTASSILGFMQTFLGGILGTLIGQAFNGTVTPLAAGFC 360 Query: 374 LCTLAALAVVLVTEKGRMFRPHHHPI 399 ++AAL ++L+ E+G+MF+PH+ PI Sbjct: 361 SVSVAALLMILIAERGKMFQPHNPPI 386 >BMEI1130 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 421 Score = 327 bits (839), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 177/381 (46%), Positives = 246/381 (64%), Gaps = 4/381 (1%) Query: 21 MDMMLPALPNIRSAFQIADANRPQMVLSIFLVGFGVGQFVMGPLSDRFGRRPVLLGGMTV 80 +D+MLP LP I ++ + N Q V++ +L+GFGV Q GPLSDRFGRR L GG+ + Sbjct: 37 VDIMLPGLPQIGASLGVHSENHVQFVITAYLLGFGVSQLFYGPLSDRFGRRLPLFGGLAI 96 Query: 81 YTIAGLLAIMAPSFETLLLARALQGLGTAATRVIATSIVRDCYAGRRMASVMSLAMMVFI 140 Y +A L + F TL++ R LQGLG AATRVIA S+VRD ++GR+MA VMSL MMVF+ Sbjct: 97 YVVAALGSAFVTDFTTLIILRVLQGLGAAATRVIAVSVVRDKFSGRQMAEVMSLVMMVFM 156 Query: 141 AVPVIAPSFGQAVMLLTHWRGIFVLLMIYGVIALAWSAMRMPETLPRELRKSLAIPEVLS 200 +PV+AP+ GQ +ML W IF+ + I ++ W+ +R+PETLP R+ L + L Sbjct: 157 ILPVVAPATGQLIMLFGEWHLIFMFMAIMALVVGLWAFLRLPETLPVSHRRPLTMKSTLG 216 Query: 201 AFRQTVTNRQTLGYALAAGGVQGSLFAFVFSSQQIFTEIFKLGHYFPVAFAACAVGVAIA 260 F +TNR L Y L + G+LF ++ S+QQIF I++LG FP+AFAA A+ +A+A Sbjct: 217 GFVIVLTNRVALFYMLGTSFILGALFGYINSAQQIFVGIYQLGTLFPLAFAAVAMTLALA 276 Query: 261 GFLNSRIVGRIGMRVISHAAL---TGFAVVAGALFIAVKTDTLSLPLFMVLSGLMMFAFG 317 FLNSR+VGR GMR IS L T F+++ L I V + + M++ +M +F Sbjct: 277 SFLNSRLVGRFGMRRISQTMLLVFTSFSLLWMVLSI-VMDGPIPFAVLMIIYMTIMLSFS 335 Query: 318 LMMANFTALAMEPQGKIAGTASSLYGTITTLLGIGVGTTIGQDYDGTLLPFATGFFLCTL 377 L+ ANF ALAMEP G++AGTASS+ G T++G +G IGQ +DGT P ATG+ + Sbjct: 336 LVTANFNALAMEPLGEVAGTASSVLGFAQTVIGAALGAVIGQAFDGTTTPVATGYCVLGF 395 Query: 378 AALAVVLVTEKGRMFRPHHHP 398 ALA VL+ E+GR+FR + P Sbjct: 396 VALACVLIAERGRLFRVQNPP 416 >AGc3403 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 438 Score = 309 bits (791), Expect = 9e-84, Method: Compositional matrix adjust. Identities = 173/400 (43%), Positives = 250/400 (62%), Gaps = 2/400 (0%) Query: 1 MGFPEFVVVIASIMALNPLAMDMMLPALPNIRSAFQIADANRPQMVLSIFLVGFGVGQFV 60 MG EF+ + A +MALN LA+D+MLP L I ++ + + N Q V+S +L+GFG+ Q + Sbjct: 37 MGRTEFIGLAAMLMALNALAIDIMLPGLQEIGASLGVVNENHRQYVISTYLLGFGIAQLL 96 Query: 61 MGPLSDRFGRRPVLLGGMTVYTIAGLLAIMAPSFETLLLARALQGLGTAATRVIATSIVR 120 GP+SDRFGRR +L G+ +Y I+ + + PSF LL+ R +QG+G+AATRVI SIVR Sbjct: 97 YGPISDRFGRRKPMLVGLAIYIISAIAVVFVPSFTGLLVLRFIQGIGSAATRVITISIVR 156 Query: 121 DCYAGRRMASVMSLAMMVFIAVPVIAPSFGQAVMLLTHWRGIFVLLMIYGVIALAWSAMR 180 D Y GR+MA VMSL MMVF+ VPVIAP GQ V+ W IF + + AW R Sbjct: 157 DIYGGRQMAEVMSLIMMVFMVVPVIAPGTGQIVLFFGDWHLIFAFMAGIAAVVTAWMYFR 216 Query: 181 MPETLPRELRKSLAIPEVLSAFRQTVTNRQTLGYALAAGGVQGSLFAFVFSSQQIFTEIF 240 +PETL + + +L F+ +TNR L Y L++ + G+LF F+ S++Q++ I+ Sbjct: 217 LPETLHPDDVRPFTARSILGGFKIVLTNRIALCYTLSSTFIFGALFGFINSAEQVYKGIY 276 Query: 241 KLGHYFPVAFAACAVGVAIAGFLNSRIVGRIGMRVISHAALTGFAVVAGALFIA--VKTD 298 LG +F AFA A+ +A + F+N+R+VGR GMR +SH +L GF + + + + Sbjct: 277 GLGAWFAAAFAGVALFMAFSSFINARLVGRFGMRKLSHGSLLGFIAITFVWLLVQILGPE 336 Query: 299 TLSLPLFMVLSGLMMFAFGLMMANFTALAMEPQGKIAGTASSLYGTITTLLGIGVGTTIG 358 + +F+V L MF FG + +NF +LAMEP G +AGTASS+ G + T+ G +G IG Sbjct: 337 PMPFAIFIVFFALAMFQFGWIGSNFNSLAMEPLGHVAGTASSVIGFMGTVGGSLIGAGIG 396 Query: 359 QDYDGTLLPFATGFFLCTLAALAVVLVTEKGRMFRPHHHP 398 Q +DGT LP GFF ++ L VL+ EKG +F+ H+ P Sbjct: 397 QAFDGTALPMVAGFFAVSIIGLIFVLIGEKGVLFQAHNKP 436 >SMc00537 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 412 Score = 308 bits (789), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 180/392 (45%), Positives = 251/392 (64%) Query: 5 EFVVVIASIMALNPLAMDMMLPALPNIRSAFQIADANRPQMVLSIFLVGFGVGQFVMGPL 64 +F+ ++A +M++N +++D+MLP L I ++ +AD N Q V++ +L+G G Q GPL Sbjct: 18 QFIALMAMLMSINAISIDIMLPGLQEIGASLGVADENHRQYVITAYLLGMGFAQLFFGPL 77 Query: 65 SDRFGRRPVLLGGMTVYTIAGLLAIMAPSFETLLLARALQGLGTAATRVIATSIVRDCYA 124 SDRFGRR LLGG+ +Y ++ L + P+F LL R +QG+G AATRVI SIVRD Y Sbjct: 78 SDRFGRRAPLLGGLALYGVSALAIVFVPTFGALLFLRLVQGIGAAATRVITVSIVRDVYG 137 Query: 125 GRRMASVMSLAMMVFIAVPVIAPSFGQAVMLLTHWRGIFVLLMIYGVIALAWSAMRMPET 184 GR+MA +MSL MMVF+ VPVIAPS GQ +ML + W IFV++ ++ V A+R+ ET Sbjct: 138 GRQMAEIMSLVMMVFMIVPVIAPSIGQLIMLFSEWHMIFVVIALFAVAVALPVALRLRET 197 Query: 185 LPRELRKSLAIPEVLSAFRQTVTNRQTLGYALAAGGVQGSLFAFVFSSQQIFTEIFKLGH 244 L R+ +L+ FR +TNR L Y LA + G+LF F+ S+QQI ++ LG Sbjct: 198 LAPANRRPFTASSILAGFRIVLTNRLALFYTLATSALLGALFGFINSAQQILVGVYGLGV 257 Query: 245 YFPVAFAACAVGVAIAGFLNSRIVGRIGMRVISHAALTGFAVVAGALFIAVKTDTLSLPL 304 +FP FAA A +A+A F NSR+V GMR +SHAAL GF + + A L LPL Sbjct: 258 WFPAVFAAFAGMMAVASFTNSRLVRTFGMRALSHAALLGFTLASFIWMSASLIGPLPLPL 317 Query: 305 FMVLSGLMMFAFGLMMANFTALAMEPQGKIAGTASSLYGTITTLLGIGVGTTIGQDYDGT 364 FM+L MF FGL+ ANF A+AMEP G +AGTASS+ G T+ G +G IGQ ++ + Sbjct: 318 FMLLHAATMFQFGLIAANFNAMAMEPLGHVAGTASSVLGFTQTIGGGIIGAFIGQAFNNS 377 Query: 365 LLPFATGFFLCTLAALAVVLVTEKGRMFRPHH 396 + P A GFF + AL VL+ E G++F+PH+ Sbjct: 378 VTPLAVGFFTVAVVALVCVLIAEGGKLFKPHN 409 >SMc00536 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 437 Score = 299 bits (766), Expect = 7e-81, Method: Compositional matrix adjust. Identities = 166/398 (41%), Positives = 240/398 (60%), Gaps = 3/398 (0%) Query: 1 MGFPEFVVVIASIMALNPLAMDMMLPALPNIRSAFQIADANRPQMVLSIFLVGFGVGQFV 60 MG EF+V IA + A LA+D MLPALP+I +A+AN Q+V+ +F +GFG+ Q Sbjct: 29 MGLVEFIVTIAVMTASIALAIDSMLPALPSIGQTLDVANANDTQLVIGVFFLGFGLSQIF 88 Query: 61 MGPLSDRFGRRPVLLGGMTVYTIAGLLAIMAPSFETLLLARALQGLGTAATRVIATSIVR 120 G LSD FGRR VLLGG+ +++++ A S ETLLL R +QG+G AA R+ +IVR Sbjct: 89 FGSLSDAFGRRSVLLGGLALFSLSMFAASWVESIETLLLLRFIQGIGGAAVRITTMAIVR 148 Query: 121 DCYAGRRMASVMSLAMMVFIAVPVIAPSFGQAVMLLTHWRGIFVLLMIYGVIALAWSAMR 180 DC+ GR MA VMS M+VF+ VP++AP+ GQ V+ W IF+L+ + G W+ R Sbjct: 149 DCFGGRDMARVMSYVMIVFMIVPIVAPTLGQVVIAYADWHWIFILIGVVGAALFVWALTR 208 Query: 181 MPETLPRELRKSLAIPEVLSAFRQTVTNRQTLGYALAAGGVQGSLFAFVFSSQQIFTEIF 240 M E+LP+E R L++ VLS FR +TNR T GY + + A+V S QQ+F E++ Sbjct: 209 MKESLPKEERLPLSVGAVLSGFRTVLTNRITCGYMIGMTLFTAVICAYVVSVQQVFGEVY 268 Query: 241 KLGHYFPVAFAACAVGVAIAGFLNSRIVGRIGMRVISHAALTGFAVVAGALFIAVKTDTL 300 L + P+AFA A G+A+A F N V GMR ISHAA+ F + A ++ T Sbjct: 269 NLSDWMPIAFAGTAGGIAVANFANGYFVRSFGMRRISHAAMILFTLFAAIGYVLSLAGTP 328 Query: 301 SLPLFMVLSGLMMFAFGLMMANFTALAMEPQGKIAGTASSLYGTITTLLGIGVGTTIGQD 360 + + +L L++ F ++ NFTA+++EP G +AGTA+++ G ++T G +G +GQ Sbjct: 329 AFAISYLLFSLLLMFFAVIATNFTAISLEPMGHLAGTATAVTGFVSTTGGALIGGAVGQL 388 Query: 361 YDGTLLPFATGFFLCTLAALAVVLVTEKGRMFRPHHHP 398 +DGTL P G+ L L + L E G++F HP Sbjct: 389 FDGTLQPLFGGYALFGLLTILATLWAENGKLFT---HP 423