BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0097.0004.p (257 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yngF [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bsu ... 140 2e-33 AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu A... 133 3e-31 PAE1383_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Py... 130 3e-30 AF0285_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu... 129 6e-30 SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ss... 128 1e-29 >BS_yngF [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bsu Bacillus subtilis Length = 260 Score = 140 bits (354), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 87/262 (33%), Positives = 137/262 (52%), Gaps = 17/262 (6%) Query: 4 IIVAKRDGIARVALNRSSARNAVTLAMWRELADIFSHFACDRDVRAVLLAGEG-KDFSVG 62 + K + +A + LNR A NA++ M R L I + ++R V+L G G K F G Sbjct: 6 LFTVKNEHMALITLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILTGTGEKAFCAG 65 Query: 63 ADISEFDSIRDDKRQAADYEVAVDACSGAIAALGKPVVAVISGYCLGGGCHLALACDFRF 122 AD+ E +++D Q + + + + AL +PV+A I+G LGGG LALACD R Sbjct: 66 ADLKERIKLKED--QVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLELALACDLRI 123 Query: 123 GDRTATIGIPSAKLSIVYGVRSVQRLLSLTGVANAKRILYSADRYRAEQAMSMGLIDEIH 182 A +G+P L+I+ G QRL L G AK +Y+ R A +A +GL++ + Sbjct: 124 ATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEAKEIGLVEHVT 183 Query: 183 ---DDAPRAAERFLKQLADNAPLSIAGAKYMLNE-----LSTGAGSLDLAMAQQFIDAAS 234 D P+ AE ++ N P+++ AK+ +N+ L+TG LA+ Q+ + Sbjct: 184 APCDLMPK-AEELAAAISANGPIAVRQAKFAINKGLETDLATG-----LAIEQKAYEQTI 237 Query: 235 DSEDFREGRRAFAEKRAPRFRG 256 ++D REG +AF EKR ++G Sbjct: 238 PTKDRREGLQAFQEKRRAVYKG 259 >AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 256 Score = 133 bits (335), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 86/253 (33%), Positives = 130/253 (51%), Gaps = 18/253 (7%) Query: 12 IARVALNRSSARNAVTLAMWRELADIFSHFACDRDVRAVLLAGEGKDFSVGADISEFDSI 71 IA LNR NA+ ELA++ + R +++ G GK F+ GADI+E Sbjct: 13 IAVATLNRPEKLNALDTKTRMELAEVIE--GIEEVARVLIITGSGKAFAAGADINELLQ- 69 Query: 72 RDDKRQAADYEVAVDACSGAIAALGKPVVAVISGYCLGGGCHLALACDFRFGDRTATIGI 131 RD + ++ D S I L PV+A ++GY LGGGC LA+ACD R A G Sbjct: 70 RDAIKAFEATKLGTDLFS-RIEELEIPVIAAVNGYTLGGGCELAMACDIRIASEKAKFGQ 128 Query: 132 PSAKLSIVYGVRSVQRLLSLTGVANAKRILYSADRYRAEQAMSMGLIDEI--HDDAPRAA 189 P L+I+ G QRL L G+ AK+++ + + A+ A+ +GL++E+ H+ A Sbjct: 129 PEINLAIIPGAGGTQRLPRLVGLGMAKKLVLTGEIIDAQTALRIGLVEEVVEHERLMERA 188 Query: 190 ERFLKQLADNAPLSIAGAKYMLNELSTGAGSLDLAMAQQFIDAAS------DSEDFREGR 243 + ++ + +PL++ AK LN S+++ + + AS SED +EG Sbjct: 189 KEVAAKIIEKSPLAVKVAKKALN------ASINMPLKEGLRYEASLFALLFSSEDAKEGM 242 Query: 244 RAFAEKRAPRFRG 256 RAF EKR P FRG Sbjct: 243 RAFLEKRKPEFRG 255 >PAE1383_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pya Pyrobaculum aerophilum Length = 259 Score = 130 bits (327), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 85/266 (31%), Positives = 129/266 (48%), Gaps = 18/266 (6%) Query: 1 VKDIIVAKRDGIARVALNRSSARNAVTLAMWRELADIFSHF-ACDRD-VRAVLLAGEGKD 58 ++ +IV GIA + LNR NA+ M EL + D D VR V++ G G+ Sbjct: 1 LETLIVRYEPGIAWIILNRPERLNAINPKMIEELWKVLDEIEQMDYDKVRVVVITGSGRA 60 Query: 59 FSVGADISEF------DSIRDDKRQAADYEVAVDACSGAIAALGKPVVAVISGYCLGGGC 112 FS GAD++ F + ++ YE + L +PV+ ++GY LGGG Sbjct: 61 FSAGADVTGFMGATPVTIFKVSRKLQMLYE--------RLELLDRPVICGLNGYTLGGGL 112 Query: 113 HLALACDFRFGDRTATIGIPSAKLSIVYGVRSVQRLLSLTGVANAKRILYSADRYRAEQA 172 LA+ACDFR TA +G P L + G QRL L G AK ++++ DR A +A Sbjct: 113 ELAMACDFRIAAETAELGQPEINLGFIPGAGGTQRLARLIGRDKAKELIFTGDRIPAREA 172 Query: 173 MSMGLIDEI--HDDAPRAAERFLKQLADNAPLSIAGAKYMLNELSTGAGSLDLAMAQQFI 230 +GL+ ++ D + F +LA+ PL++A AKY +N + + + Sbjct: 173 ERLGLVHKVVPPDRLEQELRAFANKLAEKPPLALAMAKYAINFGLEAPQWVGMMLEASNF 232 Query: 231 DAASDSEDFREGRRAFAEKRAPRFRG 256 +ED EG AF +KR P+F+G Sbjct: 233 GLLFSTEDVIEGVSAFLQKRKPQFKG 258 >AF0285_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 268 Score = 129 bits (324), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 89/264 (33%), Positives = 130/264 (49%), Gaps = 15/264 (5%) Query: 3 DIIVAKRDGIARVALNRSSARNAVTLAMWRELADIFSHFACDRDVRAVLLAGEG-KDFSV 61 +I+ + IA++ +NR NA++L E+ + D DVR V++ G G K FS Sbjct: 9 EIVKDTENKIAKLIINRPQRLNALSLDTLDEIFEALRMLEKDDDVRVVVITGAGDKAFSA 68 Query: 62 GADISEFDSIRDDKRQAADYEVAVDA--CSGAIAALGKPVVAVISGYCLGGGCHLALACD 119 G D+ + D A VA I KPV+A I+GY GGGC LALACD Sbjct: 69 GFDLQTAMQVPDFLAPANSMMVAAKGQWVFTQIERFPKPVIAAINGYAFGGGCELALACD 128 Query: 120 FRFGDRTATIGIPSAKLSIVYGVRSVQRLLSLTGVANAKRILYSADRYRAEQAMSMGLID 179 FR R A IG+ L+++ G QRL L G+ AK ++ A R A++A +GL++ Sbjct: 129 FRIMKRGAKIGLTEISLALIPGWGGTQRLPKLVGLTKAKEMIMLAKRIDADEAERIGLVN 188 Query: 180 EIHDDAPRAAER----FLKQLADNAPLSIAGAKYMLN---ELSTGAGSLDLAMAQQFIDA 232 + D P E K+LA P+S+ AKY +N EL G + + Sbjct: 189 KAVD--PEKFEEEVMALAKELAAGPPVSLRAAKYAINFGAELPAEIGQM---IEAGMFAV 243 Query: 233 ASDSEDFREGRRAFAEKRAPRFRG 256 A+ ++D EG AF ++R P F+G Sbjct: 244 ATSTQDVVEGVSAFFQRRKPEFKG 267 >SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 256 Score = 128 bits (321), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 82/262 (31%), Positives = 125/262 (47%), Gaps = 13/262 (4%) Query: 1 VKDIIVAKRDGIARVALNRSSARNAVTLAMWRELADIFSHFACDRDVRAVLLAGEGKDFS 60 + +I+ +A + LNR NA+ + EL DVR V++ G G+ FS Sbjct: 1 MNTLIIRIEPPLAWIILNRPERLNALNPELVSELDKSLDELESRSDVRVVIITGNGRAFS 60 Query: 61 VGADISEFDSIRD-DKRQAADYEVAVDACSGAIAALGKPVVAVISGYCLGGGCHLALACD 119 GAD+S F ++R D + V+ IA KP++A I+G+ LGGG LA+ACD Sbjct: 61 AGADVSSFITLRPIDVIRLRTLRNVVNK----IALYTKPIIAGINGFALGGGLELAMACD 116 Query: 120 FRFGDRTATIGIPSAKLSIVYGVRSVQRLLSLTGVANAKRILYSADRYRAEQAMSMGLID 179 R A +G P + I+ G QRL L G AK ++Y+ D AE A MGL+D Sbjct: 117 IRIASEVAQLGQPEINIGIIPGAGGTQRLPRLVGKGKAKLMIYTGDMVSAEDAYKMGLVD 176 Query: 180 EI--HDDAPRAAERFLKQLADNAPLSIAGAKYMLN---ELSTGAGSLDLAMAQQFIDAAS 234 + + R ++A+ +P+S+ AK + E + G + Sbjct: 177 LVVPSNRFEEEVRRVALKIAEKSPISLLAAKLAIELGYESNIWTGQ---TLESTLFGLLF 233 Query: 235 DSEDFREGRRAFAEKRAPRFRG 256 ++D EG +AF EKR P+F+G Sbjct: 234 TTKDVEEGVKAFLEKRKPQFKG 255