BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0096.0020.p (442 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa1328 [GEPR] COG0477 Permeases of the major facilitator superf... 787 0.0 RSc0547 [GEPR] COG0477 Permeases of the major facilitator superf... 340 5e-93 SMc04407 [GEPR] COG0477 Permeases of the major facilitator super... 328 2e-89 BMEII0406 [GEPR] COG0477 Permeases of the major facilitator supe... 321 2e-87 mlr0338 [GEPR] COG0477 Permeases of the major facilitator superf... 311 2e-84 >SMa1328 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 440 Score = 787 bits (2032), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/439 (88%), Positives = 415/439 (94%) Query: 1 MAIQVPSDFRRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVAALLSTIALFTA 60 MA+QVP+DFRRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVAALLSTIALFTA Sbjct: 1 MAVQVPTDFRRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVAALLSTIALFTA 60 Query: 61 GFLIRPLGAFLFGWMGDRVGRKYTFLITLSGMGLGTGAIGLIPTYQSIGLTAAFILFGLR 120 GFLIRPLGAFLFGWMGDRVGRKYTFLITL+GMGLGTGAIGLIPTY+SIGLTAAF+LF LR Sbjct: 61 GFLIRPLGAFLFGWMGDRVGRKYTFLITLTGMGLGTGAIGLIPTYESIGLTAAFLLFSLR 120 Query: 121 MIQGLCLGGEYGGAITYVAEHVPDHSRGYYTGWLQTSPTLGIVVSLAVIVLTRTWAGNQA 180 MIQGLCLGGEYGGAITYVAEHVPD RGYYTGWLQTSPTLGIVVSLAVI+ RT+ G++A Sbjct: 121 MIQGLCLGGEYGGAITYVAEHVPDERRGYYTGWLQTSPTLGIVVSLAVIIAARTYFGSEA 180 Query: 181 FDEWAWRVPFLVSFLLVAIAIYIRLQLQETPIFQEIKARGQMTRNPWREAFLSANIKYIL 240 FD WAWRVPFLVSFLLV IAIYIRLQLQETPIFQEIKA+GQMT+NPWREAFLS+NIKY+ Sbjct: 181 FDAWAWRVPFLVSFLLVGIAIYIRLQLQETPIFQEIKAKGQMTQNPWREAFLSSNIKYVG 240 Query: 241 IAIVVLIGQGVVWYSGQFWALYFLQQVSKVDAVTSAYIVGAALLIGTPSLIFFGWLSDQI 300 IA +VLIGQGVVWYSGQFWALYFLQQVSKVD + SAYIVGAALL+ TPSLI FGWLSD I Sbjct: 241 IATIVLIGQGVVWYSGQFWALYFLQQVSKVDPLNSAYIVGAALLLATPSLILFGWLSDII 300 Query: 301 GRKSVILGGMLLAAITYYPLYLWLGMVTQPGHINYPVAVFIIFILVCYVGMVYGPVGAFL 360 GRK VILGGMLLAA+TYYPLYLWLG VTQP +INYP+A+FIIFILVCYVGMVYGPVGAFL Sbjct: 301 GRKPVILGGMLLAALTYYPLYLWLGAVTQPDNINYPIAIFIIFILVCYVGMVYGPVGAFL 360 Query: 361 AEFFPARIRYTSVSVPYHIGNGWGGGLVPFITSAAFAATGSIGYALIYPIVVPAVCFVIA 420 AE+FP RIRYTSVSVPYHIGNGWGGGLVPFITSAAFAATGSIGYALIYPI VPAVCFV+A Sbjct: 361 AEYFPGRIRYTSVSVPYHIGNGWGGGLVPFITSAAFAATGSIGYALIYPIAVPAVCFVLA 420 Query: 421 VFIMPETRKTRIWEQIEAK 439 +F+MPETR+ IW+ IE + Sbjct: 421 IFLMPETRRISIWQPIEPR 439 >RSc0547 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 567 Score = 340 bits (871), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 168/324 (51%), Positives = 232/324 (71%), Gaps = 3/324 (0%) Query: 10 RRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVAALLSTIALFTAGFLIRPLGA 69 ++VI A+S+G + EWYDFY++GSLAA+++ +FF P AA + + F AGFL+RP GA Sbjct: 25 KKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFSGLDPTAAFIFALLAFAAGFLVRPFGA 84 Query: 70 FLFGWMGDRVGRKYTFLITLSGMGLGTGAIGLIPTYQSIGLTAAFILFGLRMIQGLCLGG 129 +FG +GD +GRKYTFLIT+ MG T +GL+P+Y +IG A IL LR++QGL LGG Sbjct: 85 LVFGRLGDMIGRKYTFLITILIMGTSTFIVGLLPSYTTIGAAAPVILIMLRLLQGLALGG 144 Query: 130 EYGGAITYVAEHVPDHSRGYYTGWLQTSPTLGIVVSLAVIVLTRTWAGNQAFDEWAWRVP 189 EYGGA TYVAEH P RG YT W+QT+ TLG+ +SL VI++ R G +F++W WR+P Sbjct: 145 EYGGAATYVAEHAPHGRRGNYTSWIQTTATLGLFLSLIVILVVRELTG-ASFEDWGWRIP 203 Query: 190 FLVSFLLVAIAIYIRLQLQETPIFQEIKARGQMTRNPWREAFLS-ANIKYILIAIVVLI- 247 FLVS +L+A ++YIRL + E+P FQ++KA G+ ++ P E+F N+K +++A+V L Sbjct: 204 FLVSIVLLATSVYIRLSMSESPAFQKMKAEGKTSKAPLTESFGQWRNLKIVILALVGLTA 263 Query: 248 GQGVVWYSGQFWALYFLQQVSKVDAVTSAYIVGAALLIGTPSLIFFGWLSDQIGRKSVIL 307 GQ VVWY+GQF+AL+FL QV KVDA T+ ++ AL IGTP +FFG LSD+IGRK +I+ Sbjct: 264 GQAVVWYTGQFYALFFLTQVLKVDAFTANVLIAVALAIGTPFFVFFGSLSDRIGRKGIIM 323 Query: 308 GGMLLAAITYYPLYLWLGMVTQPG 331 G LLA +TY+PL+ L P Sbjct: 324 AGCLLAVLTYFPLFKALTHYANPA 347 Score = 95.9 bits (237), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 54/107 (50%), Positives = 69/107 (64%) Query: 329 QPGHINYPVAVFIIFILVCYVGMVYGPVGAFLAEFFPARIRYTSVSVPYHIGNGWGGGLV 388 P +N + + I+ ILV YV MVYGP+ A L E FP RIRYTS+S+PYHIGNGW GGL+ Sbjct: 460 DPAQMNTVMVLVILVILVIYVTMVYGPIAAMLVELFPTRIRYTSMSLPYHIGNGWFGGLL 519 Query: 389 PFITSAAFAATGSIGYALIYPIVVPAVCFVIAVFIMPETRKTRIWEQ 435 P I+ A A G+I Y L YPI + A+ FVI + ET+ I+ Sbjct: 520 PTISFALVAQHGNIYYGLWYPIWIAAITFVIGALFVRETKDVDIYRH 566 >SMc04407 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 629 Score = 328 bits (840), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 160/323 (49%), Positives = 228/323 (70%), Gaps = 2/323 (0%) Query: 10 RRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVAALLSTIALFTAGFLIRPLGA 69 ++VI A+S+G + EWYDFY++GSLA + FF Q + + F AGFL+RP GA Sbjct: 20 KKVIFASSLGTVFEWYDFYLYGSLAVYIGATFFSQYPETTRNIFALLAFAAGFLVRPFGA 79 Query: 70 FLFGWMGDRVGRKYTFLITLSGMGLGTGAIGLIPTYQSIGLTAAFILFGLRMIQGLCLGG 129 +FG +GD VGRKYTFL+T+ MG+ T +G++P SIG+ A IL LR++QGL LGG Sbjct: 80 LVFGRLGDLVGRKYTFLVTILIMGVSTFLVGVLPGAASIGIAAPIILIALRLLQGLALGG 139 Query: 130 EYGGAITYVAEHVPDHSRGYYTGWLQTSPTLGIVVSLAVIVLTRTWAGNQAFDEWAWRVP 189 EYGGA TYVAEH P RGY+T W+QT+ TLG+ +SL VI+L + G +AF EW WR+P Sbjct: 140 EYGGAATYVAEHAPHGRRGYFTSWIQTTATLGLFLSLVVILLVQYMLGKEAFAEWGWRIP 199 Query: 190 FLVSFLLVAIAIYIRLQLQETPIFQEIKARGQMTRNPWREAFLS-ANIKYILIAIV-VLI 247 FL+SF+L+ ++++IRL++ E+P F+++K G+ ++ P EAF N K ++A+ ++ Sbjct: 200 FLLSFVLLGVSVWIRLKMNESPAFKKMKEEGKGSKAPLTEAFGQWRNAKIAVLALFGAVV 259 Query: 248 GQGVVWYSGQFWALYFLQQVSKVDAVTSAYIVGAALLIGTPSLIFFGWLSDQIGRKSVIL 307 GQ VVWYSGQF+AL+FLQ + KVD ++ +V A+LL+GT +FFGWLSD+IGRK +I+ Sbjct: 260 GQAVVWYSGQFYALFFLQSILKVDGQSANLMVAASLLLGTGFFVFFGWLSDKIGRKPIIM 319 Query: 308 GGMLLAAITYYPLYLWLGMVTQP 330 G+LLA +TY+PL+ L P Sbjct: 320 AGLLLAMLTYFPLFKALTWAGNP 342 Score = 112 bits (280), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 54/107 (50%), Positives = 68/107 (63%) Query: 326 MVTQPGHINYPVAVFIIFILVCYVGMVYGPVGAFLAEFFPARIRYTSVSVPYHIGNGWGG 385 MV P +N+ V + ++ +LV YV MVYGP+ A L E FP RIRYT +S+PYHIGNGW G Sbjct: 519 MVADPARVNWTVIIAVLTVLVIYVTMVYGPIAALLVELFPTRIRYTGMSLPYHIGNGWFG 578 Query: 386 GLVPFITSAAFAATGSIGYALIYPIVVPAVCFVIAVFIMPETRKTRI 432 GL+P A AA G I Y L YPIV + VI + +PET+ I Sbjct: 579 GLLPATAFAMSAAKGDIYYGLWYPIVFAGITLVIGLLFLPETKDRDI 625 >BMEII0406 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 632 Score = 321 bits (822), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 160/329 (48%), Positives = 225/329 (68%), Gaps = 2/329 (0%) Query: 4 QVPSDFRRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVAALLSTIALFTAGFL 63 ++ + R+VI A+S+G + EWYDFY++G+LA+ + FF + + + F AGF+ Sbjct: 13 KMTGEERKVIFASSLGTVFEWYDFYLYGTLASFIGAAFFNEYPEATRNIFVLLAFAAGFV 72 Query: 64 IRPLGAFLFGWMGDRVGRKYTFLITLSGMGLGTGAIGLIPTYQSIGLTAAFILFGLRMIQ 123 +RP GA +FG +GD VGRKYTFL+T+ MG T +GL+P S+G+ A IL LRM+Q Sbjct: 73 VRPFGALVFGRIGDLVGRKYTFLVTIVIMGGSTFLVGLLPGSASLGIFAPIILIALRMLQ 132 Query: 124 GLCLGGEYGGAITYVAEHVPDHSRGYYTGWLQTSPTLGIVVSLAVIVLTRTWAGNQAFDE 183 GL LGGEYGGA TYVAEH P++ RG++T W+QT+ TLG+ +SL VI+ +T AF Sbjct: 133 GLALGGEYGGAATYVAEHAPNNRRGFFTSWIQTTATLGLFLSLLVILGAQTLLSKDAFAA 192 Query: 184 WAWRVPFLVSFLLVAIAIYIRLQLQETPIFQEIKARGQMTRNPWREAFLS-ANIKYILIA 242 W WR+PFLVS LL+ I+++IR+Q+ E+P F+ +K G+ ++ P EAF N K LIA Sbjct: 193 WGWRIPFLVSVLLLGISVWIRMQMSESPAFKRMKEEGKTSKAPLSEAFGQWKNAKIALIA 252 Query: 243 IVVLI-GQGVVWYSGQFWALYFLQQVSKVDAVTSAYIVGAALLIGTPSLIFFGWLSDQIG 301 + L GQ VVWY GQF+AL+FLQ V KV+ ++ +V ALLIGT + FGWLSD+IG Sbjct: 253 LFGLTAGQAVVWYCGQFYALFFLQNVLKVENQSANIMVAIALLIGTGFFVIFGWLSDKIG 312 Query: 302 RKSVILGGMLLAAITYYPLYLWLGMVTQP 330 RK +I+ G++LAA+TY+PL+ L P Sbjct: 313 RKPIIMAGLILAAVTYFPLFKALTNAANP 341 Score = 109 bits (273), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 54/103 (52%), Positives = 69/103 (66%) Query: 326 MVTQPGHINYPVAVFIIFILVCYVGMVYGPVGAFLAEFFPARIRYTSVSVPYHIGNGWGG 385 MV P +N+ + + I+ ILV YV MVYGP+ A L E FP RIRYT +S+PYHIGNGW G Sbjct: 522 MVADPAQVNWVLTIAILTILVIYVTMVYGPIAAILVEMFPTRIRYTGMSLPYHIGNGWFG 581 Query: 386 GLVPFITSAAFAATGSIGYALIYPIVVPAVCFVIAVFIMPETR 428 GL+P A AA G I Y L YPI++ +V FVI + + ET+ Sbjct: 582 GLLPAGVFALSAAKGDIYYGLWYPIIIASVTFVIGMLFVKETK 624 >mlr0338 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 629 Score = 311 bits (797), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 161/328 (49%), Positives = 225/328 (68%), Gaps = 11/328 (3%) Query: 10 RRVIVAASVGNIIEWYDFYIFGSLAAVLSVKFFEQSHPVA-----ALLSTIALFTAGFLI 64 ++VI A+S+G + EWYDFY++GSLAA + FF + P A ALL+ F AGFL+ Sbjct: 19 KKVIFASSLGTVFEWYDFYLYGSLAAFIGSTFFSPTIPEATRNIFALLA----FAAGFLV 74 Query: 65 RPLGAFLFGWMGDRVGRKYTFLITLSGMGLGTGAIGLIPTYQSIGLTAAFILFGLRMIQG 124 RP GA +FG +GD VGRKYTFL+T++ MGL T +GL+P Y ++G+ A IL LRM+QG Sbjct: 75 RPFGALVFGRIGDLVGRKYTFLVTMTIMGLSTFLVGLLPGYATLGIAAPVILIALRMLQG 134 Query: 125 LCLGGEYGGAITYVAEHVPDHSRGYYTGWLQTSPTLGIVVSLAVIVLTRTWAGNQAFDEW 184 L LGGEYGGA TYVAEH PD RG+YT W+QT+ TLG+ +SL VI++ + + + W Sbjct: 135 LALGGEYGGAATYVAEHAPDDRRGFYTSWIQTTATLGLFLSLIVILIVQGSLSKETYAAW 194 Query: 185 AWRVPFLVSFLLVAIAIYIRLQLQETPIFQEIKARGQMTRNPWREAFLS-ANIK-YILIA 242 WR+PF+VSF+L+A++I+IRL L E+P FQ++K G+ ++ P EAF N K +L Sbjct: 195 GWRIPFIVSFVLLAVSIWIRLSLSESPTFQKMKDEGKGSKAPLSEAFGQWKNAKIALLAL 254 Query: 243 IVVLIGQGVVWYSGQFWALYFLQQVSKVDAVTSAYIVGAALLIGTPSLIFFGWLSDQIGR 302 + + GQ VVWY+GQF+AL+FLQ V KVDA + ++ AL +G+ + FGWLSD+IGR Sbjct: 255 LGLTAGQAVVWYNGQFYALFFLQNVLKVDAQSVNIMIAIALALGSIFFVVFGWLSDKIGR 314 Query: 303 KSVILGGMLLAAITYYPLYLWLGMVTQP 330 K +I+ G+ LA + +PL+ L P Sbjct: 315 KPIIMAGLALAIVCTFPLFKALTWAANP 342 Score = 103 bits (258), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 50/107 (46%), Positives = 69/107 (64%) Query: 326 MVTQPGHINYPVAVFIIFILVCYVGMVYGPVGAFLAEFFPARIRYTSVSVPYHIGNGWGG 385 M P +N+P+ + I+FILV +V MVYGP+ A L E FP RIRYT +S+PYHIGNGW G Sbjct: 519 MFADPAAVNWPMTIGILFILVLFVTMVYGPIAAILVEMFPTRIRYTGMSLPYHIGNGWFG 578 Query: 386 GLVPFITSAAFAATGSIGYALIYPIVVPAVCFVIAVFIMPETRKTRI 432 GL+P A A G I + L YP+V+ A+ +I + + +T T + Sbjct: 579 GLLPATVFALSAYRGDIYFGLWYPVVIAAMTLIIGMIFVKDTLGTDL 625