BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0094.0133.p (420 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0458 [GEPR] COG0477 Permeases of the major facilitator superf... 191 2e-48 DR1324 [GEPR] COG0477 Permeases of the major facilitator superfa... 145 1e-34 SMc02910 [GEPR] COG0477 Permeases of the major facilitator super... 109 1e-23 AGl1740 [GEPR] COG0477 Permeases of the major facilitator superf... 104 4e-22 BMEII0935 [GEPR] COG0477 Permeases of the major facilitator supe... 103 6e-22 >CAC0458 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 409 Score = 191 bits (486), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 126/398 (31%), Positives = 205/398 (51%), Gaps = 13/398 (3%) Query: 2 RRVFRSLASFNYRVWAAGALVSNIGTWMQRAAQDWLVLTQLTNHSASAVGIVMALQFGPQ 61 + F SL +++ + G +S +GTW+QR A+ WL+ T S +G + QFGP Sbjct: 6 KNTFTSLHHRDFKCFIIGQSISLMGTWLQRTAEVWLLYT--LTKSPLLLGSLSVFQFGPT 63 Query: 62 LLLMPWTGFAADHFNQRKLLMATQATMGAL-ALILGILTVTGLVQLWHVYTFAFLFGCAA 120 L+ ++G D F ++KLL TQ T+G L AL L IL T + ++ A + G + Sbjct: 64 LIFSVFSGAIVDRFPKKKLLYLTQ-TVGMLQALALFILVYTNHITAILIFILATIGGLST 122 Query: 121 ALDAPVRQTFVAELVSDTNLSNAIALNSTSFNAARMIGPAVAGLIIASVGTGWAFLFNGA 180 LD P RQ++ ELV +L NA++LNS+ FN A++IGP++AG+I+ G F N Sbjct: 123 TLDMPTRQSYFMELVGKKDLPNAVSLNSSIFNLAKIIGPSIAGIIMGKFGMSVCFFINFL 182 Query: 181 SFLAVLTSLTLLRTSELRPNARAHRTKGSVMQGFHYVWSRPDLRATLIMLFLIGTFGLNF 240 S+ AVLT L ++ N + + +G Y++ L LI + +I TF +N Sbjct: 183 SYAAVLTGLFFIKQKSYAANISSDNIFKEIKEGLKYIYENKILLKALIFMAIICTFAMNV 242 Query: 241 PIFISTMAVGVFHTDARGFGLLSSMMALGTMSGALLAAS--REEPRFGSLML---GAAIF 295 + + + V H + G+ L S M +G++ G + A R+ F L + +AIF Sbjct: 243 DVIVPVFSKTVLHKGSHGYTFLLSSMGVGSLFGTMKMAGLRRKNLNFKLLKIVGFSSAIF 302 Query: 296 GLGCTLAALAPSYWLFAAALVVIGVAALTVTNTSNALMQLSTEPAMRGRVMALRLGVALG 355 + +AA + + + A ++ G + L N SN+++QL+T RGRVM++ + G Sbjct: 303 QI---VAAFSGNLYFTAVLVLGSGFSNLCFLNGSNSILQLNTSDKYRGRVMSIYTLLNAG 359 Query: 356 GTPIGAPIVGGSADHL-GPRWALGVGAAAGFAAAIVAL 392 TPIG VG + ++L GP L G F + ++ Sbjct: 360 TTPIGNLFVGAAMNNLGGPYGFLLAGIVTAFLTTVFSI 397 >DR1324 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 430 Score = 145 bits (367), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 137/392 (34%), Positives = 196/392 (50%), Gaps = 21/392 (5%) Query: 3 RVFRSLASFNYRVWAAGALVSNIGTWMQRAAQDWLVLTQLTNHSASAVGIVMALQFGPQL 62 R F +L YR + L+S IG+WMQ AQ +LVL +L+ +S++A+ V QF P L Sbjct: 11 RTFGALRFPEYRRYWFSQLLSLIGSWMQSTAQQYLVL-ELSGNSSAALAQVTIAQFLPSL 69 Query: 63 LLMPWTGFAADHFNQRKLLMATQATMGALALILGILTVTGLVQLWHVYTFAFLFGCAAAL 122 LL + G D +R++L+ TQ T+ A+ L + T G V + V FAF+ G A A Sbjct: 70 LLSLFAGAVVDRVPRRRVLLTTQITLMTTAIALAVTTHQGSVSVPLVMVFAFISGIANAF 129 Query: 123 DAPVRQTFVAELVSDTNLSNAIALNSTSFNAARMIGPAVAGLIIASVGT----------- 171 D P RQT V + V +SNA+ALNS SFN +R IG A+ G ++A++G Sbjct: 130 DMPARQTMVVDFVPREQVSNAVALNSLSFNVSRTIGQALFG-VVAALGVSLLAGGNPDSV 188 Query: 172 ---GWAFLFNGASFLAVLTSLTLLRTSELRPNARAHRTKGSVMQGFHYVWSRPDLRATLI 228 F N SFL VL + L ++ H V +G YV + P +R ++ Sbjct: 189 ARLALPFYLNVVSFLVVLFVIATLPFPPVQERGN-HSMVDDVREGLRYVKTHPGVRNVML 247 Query: 229 MLFLIGTFGLNFPIFISTMAVGVFHTDARGFGLLSSMMALGTMSGALLAASREEPRFGSL 288 ++ + +NF + I A V+ FGLLS+ +G M+GAL AS+ P +L Sbjct: 248 LVGALSLTVINFNVIIPYYARVVYGAREATFGLLSAGFGIGAMAGALWQASKPNP-VRNL 306 Query: 289 MLGAAIFGLGCTLAALAPSYWLFAAALVVIGVAALTVTNTSNALMQLSTEPAMRGRVMAL 348 LGA + L + PS L L G LT ++N+ +QLS A+RGRVM+L Sbjct: 307 RLGATLVMLSSLALSAVPSAALALPVLAACGFGMLTFLISANSTVQLSIPDALRGRVMSL 366 Query: 349 RLGVALGGTPIGAPIVG---GSADHLGPRWAL 377 V +G P GA + LGPRW L Sbjct: 367 YSFVLVGMGPAGAALASTLISREGPLGPRWGL 398 >SMc02910 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 551 Score = 109 bits (273), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 105/362 (29%), Positives = 171/362 (47%), Gaps = 9/362 (2%) Query: 15 VWAAGALVSNIGTWMQRAAQDWLVLTQLTNHSASAVGIVMALQFGPQLLLMPWTGFAADH 74 +W A +L SN G +Q WL+ + + S + V +V A P +L +G AD+ Sbjct: 28 IWIA-SLASNFGGLIQAVGAAWLMTS--ISQSVNMVALVQASTSLPIMLFSLVSGALADN 84 Query: 75 FNQRKLLMATQATMGALALILGILTVTGLVQLWHVYTFAFLFGCAAALDAPVRQTFVAEL 134 F++R++++ Q+ M A++ +L + G+V W + F FL GC AL+ P Q V ++ Sbjct: 85 FDRRRIMLVAQSFMLAVSALLTVCAYYGIVTPWLLLIFTFLLGCGTALNNPSWQASVGDM 144 Query: 135 VSDTNLSNAIALNSTSFNAARMIGPAVAGLIIASVGTGWAFLFNGASFLAVLTSLTLLRT 194 V +L A+ALNS FN R +GPA+ G I+A+ G AF N S+ A+L +L R Sbjct: 145 VPRDDLPAAVALNSMGFNLTRSVGPAIGGAIVAAAGAAAAFAANTLSYFAILFALA--RW 202 Query: 195 SELRPNARAHRTK--GSVMQGFHYVWSRPDLRATLIMLFLIGTFGLNFPIFISTMAVGVF 252 + P R R +V G YV P++ L+ F G + +A + Sbjct: 203 KPVAPENRLPRETLGRAVSAGLRYVAMSPNIGKVLVRGFAFGLSASAILALLPLVARDLV 262 Query: 253 HTDARGFGLLSSMMALGTMSGALLAASREEPRFGSLMLGAAI--FGLGCTLAALAPSYWL 310 +G++ +G + GALL+A E ++ A F + A++P WL Sbjct: 263 GGGPLTYGVMLGAFGVGAIGGALLSARLREFLTSEAIVRYAFAGFAFSALVTAISPQAWL 322 Query: 311 FAAALVVIGVAALTVTNTSNALMQLSTEPAMRGRVMALRLGVALGGTPIGAPIVGGSADH 370 L V G + + N +QLST + GR ++L + GG G+ + G +A+ Sbjct: 323 TCLVLAVSGACWVLALSLFNTTVQLSTPRWVVGRALSLYQTMTFGGIAGGSWLWGVTAEQ 382 Query: 371 LG 372 G Sbjct: 383 YG 384 >AGl1740 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 532 Score = 104 bits (259), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 119/392 (30%), Positives = 187/392 (47%), Gaps = 8/392 (2%) Query: 15 VWAAGALVSNIGTWMQRAAQDWLVLTQLTNHSASAVGIVMALQFGPQLLLMPWTGFAADH 74 +WAA L N G++M+ A WL +T L+ S +AV +V A P LL G D Sbjct: 22 LWAATVL-GNTGSFMRDVASSWL-MTDLSA-SPAAVALVQAAGTLPIFLLAIPAGVLTDI 78 Query: 75 FNQRKLLMATQATMGALALILGILTVTGLVQLWHVYTFAFLFGCAAALDAPVRQTFVAEL 134 ++RK L+A Q + ++++ L +L TG++ + + FL G AAL P Q V EL Sbjct: 79 LDRRKFLIAVQLLLASVSVTLMVLAHTGMLSVSALIGLTFLGGIGAALMGPTWQAIVPEL 138 Query: 135 VSDTNLSNAIALNSTSFNAARMIGPAVAGLIIASVGTGWAFLFNGASFLAVLTSLTLLRT 194 V ++ +A+ALNS N AR IGPAV G+++A+ G + + + AS+ V+ +L Sbjct: 139 VKREDIKSAVALNSLGINIARSIGPAVGGILLAAFGAAFTYGADVASYFFVIAALLWWPR 198 Query: 195 SELRPNARAHRTKGSVMQGFHYVWSRPDLRATLIMLFLIGTFGLNFPIFISTMAVGVFHT 254 ++ NA G+ G Y + L L+ + F + +A + Sbjct: 199 AKNANNALQENFFGAFRAGLRYTRASRPLHVVLLRAAIFFAFASAVWALLPLVARQLLGG 258 Query: 255 DARGFGLLSSMMALGTMSGALLAASREEPRFGS--LMLGAAIF-GLGCTLAALAPSYWLF 311 DA +G+L + G ++GAL+ + RF + L+LGAAI L + AP WL Sbjct: 259 DASFYGILLGAVGAGAIAGALV-MPKLRARFDADGLLLGAAIVTALVMAGLSFAPPKWLA 317 Query: 312 AAALVVIGVAALTVTNTSNALMQLSTEPAMRGRVMALRLGVALGGTPIGAPIVGGSADHL 371 L+ +G A +T T N Q +RGR +A+ L V G G+ G + Sbjct: 318 IIILLFLGGAWITALTTLNGAAQAILPNWVRGRGLAVYLTVFNGAMTAGSIGWGAVGEAA 377 Query: 372 GPRWALGVGAAAGFAAAIVALGMLSRSGGEAE 403 G L +GAA F A ++ + L G+A+ Sbjct: 378 GVPGTLLIGAAGLFIAGLI-MHRLKLPAGDAD 408 >BMEII0935 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 344 Score = 103 bits (258), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 81/278 (29%), Positives = 138/278 (49%), Gaps = 2/278 (0%) Query: 69 GFAADHFNQRKLLMATQATMGALALILGILTVTGLVQLWHVYTFAFLFGCAAALDAPVRQ 128 G AD+F++R++++ Q + +++IL ++ W + +F FL GC AL P Q Sbjct: 65 GALADNFDRRRIMLVAQILLLGISVILAACAYFNVLTPWMLLSFTFLIGCGGALHNPSWQ 124 Query: 129 TFVAELVSDTNLSNAIALNSTSFNAARMIGPAVAGLIIASVGTGWAFLFNGASFLAVLTS 188 + ++V +L A+ALNS SFN R IGPA+ GLI+A+ G +AF+FN S+ A++ + Sbjct: 125 ASMGDIVPRHDLPAAVALNSMSFNLMRSIGPAIGGLIVAAAGAAFAFIFNAFSYCALILA 184 Query: 189 LTLLRTSELRPNARAHRTKGSVMQGFHYVWSRPDLRATLIMLFLIGTFGLNFPIFISTMA 248 L + + + G+++ G YV P+L + FL G + + +A Sbjct: 185 LWQWKPQTAKSTLPREKFGGAMVAGLRYVSMSPNLLKVMFRGFLFGLSAIVILALLPLVA 244 Query: 249 VGVFHTDARGFGLLSSMMALGTMSGALLAASREEPRFGSLMLGAAI--FGLGCTLAALAP 306 + A +G++ LG + GA+L+A E ++ + F C L +L+ Sbjct: 245 RDLVKGTALTYGIMLGFFGLGAIGGAILSARLRELMGNEWLVRGSFVAFAASCVLLSLSR 304 Query: 307 SYWLFAAALVVIGVAALTVTNTSNALMQLSTEPAMRGR 344 WL L+ GVA + + N +QLST + GR Sbjct: 305 QMWLSCLFLLPAGVAWVLALSLFNVTVQLSTPRWVVGR 342