BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0094.0088.p (245 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0266 [J] COG0101 Pseudouridylate synthase Bme Brucella meli... 317 1e-86 mll4852 [J] COG0101 Pseudouridylate synthase Mlo Mesorhizobium loti 311 1e-84 SMc01099 [J] COG0101 Pseudouridylate synthase Sme Sinorhizobium ... 306 3e-83 CC0278 [J] COG0101 Pseudouridylate synthase Ccr Caulobacter vibr... 291 1e-78 AGc644 [J] COG0101 Pseudouridylate synthase Atu Agrobacterium tu... 290 2e-78 >BMEII0266 [J] COG0101 Pseudouridylate synthase Bme Brucella melitensis Length = 251 Score = 317 bits (813), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 159/247 (64%), Positives = 185/247 (74%), Gaps = 2/247 (0%) Query: 1 MPRYKLTIEYDGTPFSGWQIQDTAPTVQGALEAAVKAICGEDVRVHGAGRTDAGVHARGQ 60 MPRYKLT+EYDGTP+ GWQ Q+ VQGA+E A K CGED+ + AGRTDAGVHA Q Sbjct: 1 MPRYKLTVEYDGTPYVGWQRQENGHAVQGAIEQAFKKFCGEDLTLSAAGRTDAGVHATAQ 60 Query: 61 VAHCDIAKHFPPGRFRDGLNAHL--RPNPIGVLAADVVPDDFEARFSATRRHYLYRITNT 118 VAH D+AK + G+ RD +NAHL I +L + D F+ARFSA RHYLYRI N Sbjct: 61 VAHVDLAKDWGAGKVRDAVNAHLVMADERISILNVEKTTDTFDARFSARARHYLYRIHNR 120 Query: 119 RANLALDIGRVWRVPRALDADAMHDAAQRLLGKHDFTTFRDTECQARSPEKTLDQLDVTR 178 RA LA+D R W V + LDADAMH+AAQRLLG+HDFTTFR T+CQA+SP KTLD+LDVTR Sbjct: 121 RAPLAVDYQRAWWVQKQLDADAMHEAAQRLLGEHDFTTFRATQCQAKSPVKTLDRLDVTR 180 Query: 179 EGDAVNIVTSARSFLHSQVRSMVGSLVWVGEGRWSADDLAAALAARNRAACGPVAPPDGL 238 GD V + SARSFLH+QVRS GSL+ VG GRW+ADDL AAL AR+R ACG VAPP GL Sbjct: 181 NGDMVEMRVSARSFLHNQVRSFAGSLMEVGVGRWTADDLQAALEARDRKACGQVAPPYGL 240 Query: 239 YLMRVDY 245 YL+ VDY Sbjct: 241 YLVGVDY 247 >mll4852 [J] COG0101 Pseudouridylate synthase Mlo Mesorhizobium loti Length = 248 Score = 311 bits (796), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 153/247 (61%), Positives = 191/247 (77%), Gaps = 2/247 (0%) Query: 1 MPRYKLTIEYDGTPFSGWQIQDTAPTVQGALEAAVKAICGEDVRVHGAGRTDAGVHARGQ 60 MPR++L IEYDG+ F+GWQ Q P+VQ A+E A++ CGE VR+ AGRTDAGVHA Q Sbjct: 1 MPRFRLDIEYDGSLFAGWQHQADQPSVQQAIEQAIEKFCGEAVRLRAAGRTDAGVHASAQ 60 Query: 61 VAHCDIAKHFPPGRFRDGLNAHLRPNP--IGVLAADVVPDDFEARFSATRRHYLYRITNT 118 VAH D+AK +P + RD +NAHL+ + +L A +VPDDF+ARFSAT RHYLYRI N Sbjct: 61 VAHVDLAKPWPGDKVRDAVNAHLQAAGAHVAILKAAIVPDDFDARFSATGRHYLYRILNR 120 Query: 119 RANLALDIGRVWRVPRALDADAMHDAAQRLLGKHDFTTFRDTECQARSPEKTLDQLDVTR 178 RA AL+ G+VW VP+ LDA AMH+AA+ LLG+HDFTTFR T+CQA SP +TL++LDV+R Sbjct: 121 RAPAALEKGKVWWVPKRLDAGAMHEAAKLLLGRHDFTTFRSTQCQANSPVRTLERLDVSR 180 Query: 179 EGDAVNIVTSARSFLHSQVRSMVGSLVWVGEGRWSADDLAAALAARNRAACGPVAPPDGL 238 GD + + SARSFLH+QVRSMVGSL VG+G W+ +L AAL AR+RAACG VAPPDGL Sbjct: 181 AGDMIEVRASARSFLHNQVRSMVGSLKRVGDGGWTEAELKAALEARDRAACGQVAPPDGL 240 Query: 239 YLMRVDY 245 +L+ VDY Sbjct: 241 FLIGVDY 247 >SMc01099 [J] COG0101 Pseudouridylate synthase Sme Sinorhizobium meliloti Length = 247 Score = 306 bits (783), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 148/247 (59%), Positives = 183/247 (74%), Gaps = 2/247 (0%) Query: 1 MPRYKLTIEYDGTPFSGWQIQDTAPTVQGALEAAVKAICGEDVRVHGAGRTDAGVHARGQ 60 MPRY+LT+EYDG+ + GWQ QD P+VQGA+E AV ++ E V + GAGRTD+GVHARGQ Sbjct: 1 MPRYRLTVEYDGSDYVGWQRQDNGPSVQGAIEKAVLSLTRETVSIRGAGRTDSGVHARGQ 60 Query: 61 VAHCDIAKHFPPGRFRDGLNAHLR--PNPIGVLAADVVPDDFEARFSATRRHYLYRITNT 118 VAH D+ + + ++ LNAHL + +L P DF+ARFSA RRHYLYRI + Sbjct: 61 VAHLDLTREWKSYTLQNALNAHLALAGERVSILDVAEAPGDFDARFSAIRRHYLYRIISR 120 Query: 119 RANLALDIGRVWRVPRALDADAMHDAAQRLLGKHDFTTFRDTECQARSPEKTLDQLDVTR 178 R+ LAL+ R W VP+ LD DAMH+AAQRL+G HDFTTFR CQA SP +TLD+LDVTR Sbjct: 121 RSPLALEARRAWWVPKPLDHDAMHEAAQRLVGHHDFTTFRSAHCQATSPLRTLDRLDVTR 180 Query: 179 EGDAVNIVTSARSFLHSQVRSMVGSLVWVGEGRWSADDLAAALAARNRAACGPVAPPDGL 238 G+ + I +A+SFLH+Q+RS GSL VGEG+W+ DDL AAL AR+R ACGPVAPPDGL Sbjct: 181 AGELIEIRATAQSFLHNQIRSFAGSLKLVGEGKWTPDDLQAALEARDRKACGPVAPPDGL 240 Query: 239 YLMRVDY 245 Y MRVDY Sbjct: 241 YFMRVDY 247 >CC0278 [J] COG0101 Pseudouridylate synthase Ccr Caulobacter vibrioides Length = 247 Score = 291 bits (745), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 143/245 (58%), Positives = 177/245 (72%) Query: 1 MPRYKLTIEYDGTPFSGWQIQDTAPTVQGALEAAVKAICGEDVRVHGAGRTDAGVHARGQ 60 MPRY+L +EYDG P++G+Q Q T P+VQGA+EAAVKA CG++VR+ AGRTD GVHA GQ Sbjct: 1 MPRYRLLVEYDGRPYAGFQAQATLPSVQGAIEAAVKAFCGQEVRIAAAGRTDTGVHATGQ 60 Query: 61 VAHCDIAKHFPPGRFRDGLNAHLRPNPIGVLAADVVPDDFEARFSATRRHYLYRITNTRA 120 V H D+ K +P + LNAHL + +L+A+V + + ARFSA R YLYRI N RA Sbjct: 61 VVHVDLDKDWPAQTVFNALNAHLTREAVSILSAEVAEEGWHARFSANERRYLYRILNRRA 120 Query: 121 NLALDIGRVWRVPRALDADAMHDAAQRLLGKHDFTTFRDTECQARSPEKTLDQLDVTREG 180 ALD GRVW + + LD +AMH AAQ L+G HDFTTFRD CQ++SP KTLD V R G Sbjct: 121 PPALDKGRVWHMKKDLDHEAMHAAAQHLIGLHDFTTFRDMHCQSKSPVKTLDVARVRRVG 180 Query: 181 DAVNIVTSARSFLHSQVRSMVGSLVWVGEGRWSADDLAAALAARNRAACGPVAPPDGLYL 240 + +++ ARSFLH QVRSM G+LV VG GRW+ DD+ AAL AR+R CGPVAP DGLYL Sbjct: 181 EEIHLDFEARSFLHRQVRSMTGTLVEVGAGRWTVDDVKAALEARDRRECGPVAPADGLYL 240 Query: 241 MRVDY 245 + V Y Sbjct: 241 VGVGY 245 >AGc644 [J] COG0101 Pseudouridylate synthase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 266 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 144/247 (58%), Positives = 185/247 (74%), Gaps = 2/247 (0%) Query: 1 MPRYKLTIEYDGTPFSGWQIQDTAPTVQGALEAAVKAICGEDVRVHGAGRTDAGVHARGQ 60 MPR+++T+EYDGTP+ GWQ Q+ P+VQGALEAAV+++ GE V + GAGRTD+GVHA GQ Sbjct: 1 MPRFRMTVEYDGTPYYGWQRQENGPSVQGALEAAVRSLTGESVSIRGAGRTDSGVHAVGQ 60 Query: 61 VAHCDIAKHFPPGRFRDGLNAHLRP--NPIGVLAADVVPDDFEARFSATRRHYLYRITNT 118 VAH D+++ + P + R+ LNAHL + VL A V +DF+ARFSA RRHYLYRI Sbjct: 61 VAHIDLSRDWEPYKLRNALNAHLAMAGEAVAVLDAAAVTEDFDARFSALRRHYLYRIICR 120 Query: 119 RANLALDIGRVWRVPRALDADAMHDAAQRLLGKHDFTTFRDTECQARSPEKTLDQLDVTR 178 ++ LAL+ R W V + LD + MH+AAQ L+G+HDFTTFR CQA SP +TLD+LDVTR Sbjct: 121 KSRLALEHKRAWWVSKDLDHERMHEAAQMLVGRHDFTTFRSVHCQANSPVRTLDRLDVTR 180 Query: 179 EGDAVNIVTSARSFLHSQVRSMVGSLVWVGEGRWSADDLAAALAARNRAACGPVAPPDGL 238 GD + I +A+SFLH+Q+RS G+L GEG + DD+ AAL AR+R ACGPVAPPDGL Sbjct: 181 NGDLIEIRATAQSFLHNQIRSFAGTLKLAGEGGMTPDDVRAALEARDRKACGPVAPPDGL 240 Query: 239 YLMRVDY 245 Y M+VDY Sbjct: 241 YFMQVDY 247