BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0094.0084.p (458 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3162 [GEPR] COG0477 Permeases of the major facilitator superf... 270 4e-72 RSc0154 [GEPR] COG0477 Permeases of the major facilitator superf... 267 4e-71 ampG [GEPR] COG0477 Permeases of the major facilitator superfami... 260 4e-69 ZampG [GEPR] COG0477 Permeases of the major facilitator superfam... 260 4e-69 ECs0487 [GEPR] COG0477 Permeases of the major facilitator superf... 260 4e-69 >YPO3162 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 492 Score = 270 bits (691), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 170/415 (40%), Positives = 243/415 (58%), Gaps = 25/415 (6%) Query: 29 VYLQPRVLIVLLLGFSSGLPLALSGSTLQVWMKEAGVDLGTIGLLALIGTPYTLKFLWAP 88 ++ Q +I+LLLGF+SGLPLAL+ TLQ WM V+L TIG+ +L+G Y KFLW+P Sbjct: 8 LFTQRNSIILLLLGFASGLPLALTSGTLQAWMTVENVNLKTIGIFSLVGQAYVFKFLWSP 67 Query: 89 LVDALHVPLFTQMFGRRRGWLLFSQLLLIAAILVLAMADPARSPWFAAFAALLVATASST 148 L+D + P F GRRRGWLL SQLLLI AI+ + +PA+ W+ A A+LVA S++ Sbjct: 68 LMDR-YTPSF---LGRRRGWLLVSQLLLIIAIIAMGFMEPAKHLWWLAAVAVLVAFCSAS 123 Query: 149 QDIVVDAFRVESLPESEQAAGMASYVAAYRVGMLVSTAGALFIVSGFESAGLARPSAWMW 208 QDIV DA++ + L E+ G A V YR+ MLVS AL+I R W Sbjct: 124 QDIVFDAYKTDLLTTEERGTGAAVSVLGYRLAMLVSGGLALWIAD--------RYLGWQS 175 Query: 209 GYVVMAVLVVIGIITALAATEPAQSKGAETATHAQNAAERVLHAALGA-FSEFLSRKDAF 267 Y +MA L++IG+ L A EP + A + L A+ A +F R +A+ Sbjct: 176 TYWLMAGLMLIGVFATLLAPEP----------DIRIAPPKTLEQAIVAPLRDFFGRNNAW 225 Query: 268 AALAFVVLFKFTDAFSGTMTAPFVID-IGFSKVDYAAIVKGVGLAATLIGGFAGGFVARR 326 L +V +K DAF+ +++ F+I +GF + + K +GL AT+IG GG + +R Sbjct: 226 LILLLIVFYKMGDAFAASLSTTFLIRGVGFDAGEVGLVNKTLGLIATIIGALYGGLLMQR 285 Query: 327 YSLATSLWIGGVLQAVANLSFSWLAHVGVDQWALALAITAENFTSAIGTVIFVAYLSALC 386 SL +L I G+LQAV+N+ + LA + +++ AI EN +GT FVA L LC Sbjct: 286 LSLFRALMIFGILQAVSNMGYWLLAITDKNIFSMGSAIFLENLCGGMGTAAFVALLMTLC 345 Query: 387 RNPLHTATQYALLTALAAVGRTYLSSGAGYVAKAVGWQVFFVICVLVAIPSLILL 441 N +ATQ+ALL+AL+AVGR Y+ AG+ +A GW +F++ + AIP L+LL Sbjct: 346 -NKSFSATQFALLSALSAVGRVYVGPIAGWFVEAHGWPLFYLFSIAAAIPGLLLL 399 >RSc0154 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 426 Score = 267 bits (683), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 177/426 (41%), Positives = 247/426 (57%), Gaps = 24/426 (5%) Query: 22 SWRDSLAVYLQPRVLIVLLLGFSSGLPLALSGSTLQVWMKEAGVDLGTIGLLALIGTPYT 81 ++ D L V+ R+ +LLLGF+SGLPLAL+ TLQ WM G+D+ TIGL +L+G Y Sbjct: 2 TFHDYLDVFRNRRIGAMLLLGFASGLPLALTSGTLQAWMTVEGLDIRTIGLFSLVGQAYI 61 Query: 82 LKFLWAPLVDALHVPLFTQMFGRRRGWLLFSQLLLIAAILVLAMADPARSPWFAAFAALL 141 KFLWAPL+D PL GRRRGWL+ +Q L A+I +A P + W A A+L Sbjct: 62 FKFLWAPLMDRFTPPL----IGRRRGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVL 117 Query: 142 VATASSTQDIVVDAFRVESLPESEQAAGMASYVAAYRVGMLVSTAGALFIVSGFESAGLA 201 VA S++QDIV DA+ + L SE+ G A V YR+ MLVS AL++ Sbjct: 118 VAFLSASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVSGGLALWLAD-------- 169 Query: 202 RPSAWMWGYVVMAVLVVIGIITALAATEPAQSKGAETATHAQNAAERVLHAALGAFSEFL 261 R W Y++MA L+ + ++ L + EP E A + + A +G +F Sbjct: 170 RVMGWSSMYLLMAGLMALFVLATLWSPEP------EAAARPPRSLQ---EAVVGPLRDFF 220 Query: 262 SRKDAFAALAFVVLFKFTDAFSGTMTAPFVID-IGFSKVDYAAIVKGVGLAATLIGGFAG 320 +R+ A+A LA +VL+K DAF+G+++ F+I +GFS + + K +GL AT+IG G Sbjct: 221 ARRGAWALLALIVLYKLGDAFAGSLSTTFLIRGVGFSAGEVGIVNKTLGLVATIIGALYG 280 Query: 321 GFVARRYSLATSLWIGGVLQAVANLSFSWLAHVGVDQWALALAITAENFTSAIGTVIFVA 380 G + R L +L + GVLQAV+NL + LA W +ALAI EN +GT FVA Sbjct: 281 GTLMVRLGLVRALLLFGVLQAVSNLGYWVLAVTPQHLWTMALAIGIENLCGGMGTAAFVA 340 Query: 381 YLSALCRNPLHTATQYALLTALAAVGRTYLSSGAGYVAKAVGWQVFFVICVLVAIPSLIL 440 L ALC N +ATQYALL+ALA++GR Y+ +GY+ +A GW F+++ V A P L L Sbjct: 341 LLMALC-NRSFSATQYALLSALASIGRVYVGPTSGYLVEAYGWPAFYLMTVAFAFPGLAL 399 Query: 441 LAWLQR 446 L W R Sbjct: 400 L-WCMR 404 >ampG [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 491 Score = 260 bits (665), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 162/416 (38%), Positives = 235/416 (56%), Gaps = 23/416 (5%) Query: 27 LAVYLQPRVLIVLLLGFSSGLPLALSGSTLQVWMKEAGVDLGTIGLLALIGTPYTLKFLW 86 L ++ QPR I+L+LGF+SGLPLAL+ TLQ WM +DL TIG +L+G Y KFLW Sbjct: 6 LRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYVFKFLW 65 Query: 87 APLVDALHVPLFTQMFGRRRGWLLFSQLLLIAAILVLAMADPARSPWFAAFAALLVATAS 146 +PL+D P FGRRRGWLL +Q+LL+ AI + +P + A A+++A S Sbjct: 66 SPLMDRYTPPF----FGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 Query: 147 STQDIVVDAFRVESLPESEQAAGMASYVAAYRVGMLVSTAGALFIVSGFESAGLARPSAW 206 ++QDIV DA++ + LP E+ AG A V YR+GMLVS AL++ + W Sbjct: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLAD--------KWLGW 173 Query: 207 MWGYVVMAVLVVIGIITALAATEPAQSKGAETATHAQNAAERVLHAALGAFSEFLSRKDA 266 Y +MA L++ II L A EP T + + A + +F R +A Sbjct: 174 QGMYWLMAALLIPCIIATLLAPEP---------TDTIPVPKTLEQAVVAPLRDFFGRNNA 224 Query: 267 FAALAFVVLFKFTDAFSGTMTAPFVID-IGFSKVDYAAIVKGVGLAATLIGGFAGGFVAR 325 + L +VL+K DAF+ ++T F+I +GF + + K +GL AT++G GG + + Sbjct: 225 WLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQ 284 Query: 326 RYSLATSLWIGGVLQAVANLSFSWLAHVGVDQWALALAITAENFTSAIGTVIFVAYLSAL 385 R SL +L I G+LQ +N + L+ +++ A+ EN +GT FVA L L Sbjct: 285 RLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTL 344 Query: 386 CRNPLHTATQYALLTALAAVGRTYLSSGAGYVAKAVGWQVFFVICVLVAIPSLILL 441 C N +ATQ+ALL+AL+AVGR Y+ AG+ +A GW F++ V A+P LILL Sbjct: 345 C-NKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAAVPGLILL 399 >ZampG [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 491 Score = 260 bits (665), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 162/416 (38%), Positives = 235/416 (56%), Gaps = 23/416 (5%) Query: 27 LAVYLQPRVLIVLLLGFSSGLPLALSGSTLQVWMKEAGVDLGTIGLLALIGTPYTLKFLW 86 L ++ QPR I+L+LGF+SGLPLAL+ TLQ WM +DL TIG +L+G Y KFLW Sbjct: 6 LRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYVFKFLW 65 Query: 87 APLVDALHVPLFTQMFGRRRGWLLFSQLLLIAAILVLAMADPARSPWFAAFAALLVATAS 146 +PL+D P FGRRRGWLL +Q+LL+ AI + +P + A A+++A S Sbjct: 66 SPLMDRYTPPF----FGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 Query: 147 STQDIVVDAFRVESLPESEQAAGMASYVAAYRVGMLVSTAGALFIVSGFESAGLARPSAW 206 ++QDIV DA++ + LP E+ AG A V YR+GMLVS AL++ + W Sbjct: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLAD--------KWLGW 173 Query: 207 MWGYVVMAVLVVIGIITALAATEPAQSKGAETATHAQNAAERVLHAALGAFSEFLSRKDA 266 Y +MA L++ II L A EP T + + A + +F R +A Sbjct: 174 QGMYWLMAALLIPCIIATLLAPEP---------TDTIPVPKTLEQAVVAPLRDFFGRNNA 224 Query: 267 FAALAFVVLFKFTDAFSGTMTAPFVID-IGFSKVDYAAIVKGVGLAATLIGGFAGGFVAR 325 + L +VL+K DAF+ ++T F+I +GF + + K +GL AT++G GG + + Sbjct: 225 WLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQ 284 Query: 326 RYSLATSLWIGGVLQAVANLSFSWLAHVGVDQWALALAITAENFTSAIGTVIFVAYLSAL 385 R SL +L I G+LQ +N + L+ +++ A+ EN +GT FVA L L Sbjct: 285 RLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTL 344 Query: 386 CRNPLHTATQYALLTALAAVGRTYLSSGAGYVAKAVGWQVFFVICVLVAIPSLILL 441 C N +ATQ+ALL+AL+AVGR Y+ AG+ +A GW F++ V A+P LILL Sbjct: 345 C-NKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAAVPGLILL 399 >ECs0487 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 491 Score = 260 bits (665), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 162/416 (38%), Positives = 235/416 (56%), Gaps = 23/416 (5%) Query: 27 LAVYLQPRVLIVLLLGFSSGLPLALSGSTLQVWMKEAGVDLGTIGLLALIGTPYTLKFLW 86 L ++ QPR I+L+LGF+SGLPLAL+ TLQ WM +DL TIG +L+G Y KFLW Sbjct: 6 LRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYVFKFLW 65 Query: 87 APLVDALHVPLFTQMFGRRRGWLLFSQLLLIAAILVLAMADPARSPWFAAFAALLVATAS 146 +PL+D P FGRRRGWLL +Q+LL+ AI + +P + A A+++A S Sbjct: 66 SPLMDRYTPPF----FGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 Query: 147 STQDIVVDAFRVESLPESEQAAGMASYVAAYRVGMLVSTAGALFIVSGFESAGLARPSAW 206 ++QDIV DA++ + LP E+ AG A V YR+GMLVS AL++ + W Sbjct: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLAD--------KWLGW 173 Query: 207 MWGYVVMAVLVVIGIITALAATEPAQSKGAETATHAQNAAERVLHAALGAFSEFLSRKDA 266 Y +MA L++ II L A EP T + + A + +F R +A Sbjct: 174 QGMYWLMAALLIPCIIATLLAPEP---------TDTIPVPKTLEQAVVAPLRDFFGRNNA 224 Query: 267 FAALAFVVLFKFTDAFSGTMTAPFVID-IGFSKVDYAAIVKGVGLAATLIGGFAGGFVAR 325 + L +VL+K DAF+ ++T F+I +GF + + K +GL AT++G GG + + Sbjct: 225 WLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQ 284 Query: 326 RYSLATSLWIGGVLQAVANLSFSWLAHVGVDQWALALAITAENFTSAIGTVIFVAYLSAL 385 R SL +L I G+LQ +N + L+ +++ A+ EN +GT FVA L L Sbjct: 285 RLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTL 344 Query: 386 CRNPLHTATQYALLTALAAVGRTYLSSGAGYVAKAVGWQVFFVICVLVAIPSLILL 441 C N +ATQ+ALL+AL+AVGR Y+ AG+ +A GW F++ V A+P LILL Sbjct: 345 C-NKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAAVPGLILL 399