BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0094.0070.p         (213 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF0907 [GEPR] COG0477 Permeases of the major facilitator superfa...    94   2e-19
MA4166 [GEPR] COG0477 Permeases of the major facilitator superfa...    91   2e-18
Cgl2173 [GEPR] COG0477 Permeases of the major facilitator superf...    71   2e-12
yjiZ [GEPR] COG0477 Permeases of the major facilitator superfami...    60   2e-09
BS_yybO [GEPR] COG0477 Permeases of the major facilitator superf...    60   5e-09

>AF0907 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu
           Archaeoglobus fulgidus
          Length = 419

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 55/157 (35%), Positives = 83/157 (52%), Gaps = 2/157 (1%)

Query: 1   LIAAPLTSELGLDAGDLGLLTSVYFLTFAVAQIPVGILLDRYGPRLIQSVLLVAAAVGAA 60
           ++A  L  E  + A  +G+L+S YF  + + QIPVG L D  GPRL  +V  + A VG  
Sbjct: 43  ILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYLSDTKGPRLTTTVFTLLAFVGTV 102

Query: 61  LFATSDNLLMLLLGRALLGLGVAASLTAGLKALVLWFPKDRLPFLNGLMVMLGALGAVTT 120
           LFA S N  + +LGR L+G+GV+      +K L  WF  D    L G++  +G +GA+ +
Sbjct: 103 LFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGVLFAVGNMGALVS 162

Query: 121 TSPAQWLLAWVGWRTLFALLA--VFTAGCSAMIYLDD 155
             P   +++  GWR  F  +    F    S  I++ D
Sbjct: 163 AYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRD 199


>MA4166 [GEPR] COG0477 Permeases of the major facilitator superfamily Mac
           Methanosarcina acetivorans str.C2A
          Length = 444

 Score = 90.5 bits (223), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 50/145 (34%), Positives = 84/145 (57%), Gaps = 1/145 (0%)

Query: 1   LIAAPLTSELGLDAGDLGLLTSVYFLTFAVAQIPVGILLDRYGPRLIQSVLLVAAAVGAA 60
           ++AA + +  G+ A  +GLL S YF  +   Q+P GIL D +G +    V  + AAVGA 
Sbjct: 27  VVAADIMNTFGVGAASIGLLGSAYFYAYTAMQLPSGILSDSWGVKKTAGVFTLLAAVGAV 86

Query: 61  LFATSDNLLMLLLGRALLGLGVAASLTAGLKALVLWFPKDRLPFLNGLMVMLGALGAVTT 120
           L   + N  M+L+GR L+G+GVA      +K L +WF K+    ++G+++ +G +GA++ 
Sbjct: 87  LTGVASNFTMVLIGRVLIGIGVAMVYIPVMKVLAIWFKKNEFASMSGVLLAIGNIGALSA 146

Query: 121 TSPAQWLLAWVG-WRTLFALLAVFT 144
             P   + A  G W+ +F +L +F+
Sbjct: 147 AGPLAIMAAAFGDWQKVFLMLGLFS 171


>Cgl2173 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl
           Corynebacterium glutamicum
          Length = 408

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 65/132 (49%)

Query: 9   ELGLDAGDLGLLTSVYFLTFAVAQIPVGILLDRYGPRLIQSVLLVAAAVGAALFATSDNL 68
              +DA  + + TSV    +A AQIP+GIL+D++GPR + ++  +   +G  +   +D+ 
Sbjct: 20  RFQVDATRIAVFTSVQVGVYAFAQIPMGILIDKFGPRKLLAIGALVMGIGQLILGFTDSY 79

Query: 69  LMLLLGRALLGLGVAASLTAGLKALVLWFPKDRLPFLNGLMVMLGALGAVTTTSPAQWLL 128
            + ++ R  +G G A+   + ++ L  WFP    P    L   LG LG   +  P   LL
Sbjct: 80  SIAIIARVFIGAGDASIFLSVMRILPFWFPLKHTPIFTQLTTCLGQLGQFFSAVPFMALL 139

Query: 129 AWVGWRTLFALL 140
              GW   F  L
Sbjct: 140 GAQGWPVAFVSL 151


>yjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco
           Escherichia coli K12
          Length = 453

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 55/187 (29%), Positives = 85/187 (45%), Gaps = 6/187 (3%)

Query: 6   LTSELGLDAGDLGLLTSVYFLTFAVAQIPVGILLDRYGPRLIQSVLLVAAAVGAALFATS 65
           +  ELGL A ++G L SV+ L + +AQ+P G LLDR GPRL+  + +   ++  A+    
Sbjct: 68  IREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMV 127

Query: 66  DNLLMLLLGRALLGLGVAASLTAGLKALVLWFPKDRLPFLNGLMVMLGALGAVTTTSPAQ 125
            N    +L R  +G+G A     G+K +  WF         G       +G   +     
Sbjct: 128 HNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILA 187

Query: 126 WLLAWVGWRTLF---ALLAVFTAGCSAMIY--LDDLSLGAGE-CIGNAGPAWNSRGQLEE 179
            ++  +GWR +F    +L +F A    M+Y   + + L A E    NAG     R  L  
Sbjct: 188 AMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSF 247

Query: 180 DLYRSAF 186
             +RS F
Sbjct: 248 AEWRSLF 254


>BS_yybO [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu
           Bacillus subtilis
          Length = 435

 Score = 59.7 bits (143), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 6/152 (3%)

Query: 2   IAAP-LTSELGLDAGDLGLLTSVYFLTFAVAQIPVGILLDRYGPRLIQSVLLVAAAVGAA 60
           +AAP +     L A +LG++ S+Y  ++ + Q+PVG LLDR+G   +  V +   +    
Sbjct: 43  VAAPAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSLLDRFGVAWVTRVGMTIWSFLTI 102

Query: 61  LFATSDNLLMLLLGRALLGLGVAASLTAGLKALVLWFPKDRLPFLNGLMVMLGALGAVTT 120
           L A     L+L L R L+GL  A++  A  KA  LWFP       N L         V  
Sbjct: 103 LLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNVIG 162

Query: 121 TSPAQWLLAWVGWRTLFALLAVFTAGCSAMIY 152
                +L+    WR     +A  T GC  +++
Sbjct: 163 APLVAFLVTTFDWR-----VAFLTIGCINVLF 189