BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0094.0056.p         (192 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SMb20213_2 [OC] COG0526 Thiol-disulfide isomerase and thioredoxi...   163   2e-40
MT2942_2 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins...   156   2e-38
Rv2874_2 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins...   152   4e-37
alr1013_1 [OC] COG0526 Thiol-disulfide isomerase and thioredoxin...   113   2e-25
BH2664 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins B...    88   1e-17

>SMb20213_2 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Sme
           Sinorhizobium meliloti
          Length = 346

 Score =  163 bits (412), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 74/138 (53%), Positives = 89/138 (64%)

Query: 51  PEFAGISNWFNSKPLKLADLRGKVVLVDFWTYGCVNCVNTLPHVTQLYSKYRDRGLVVIG 110
           P   G   W NSKPL +  LRGKVVLVDFWTY C+NC+ T+P+V     KYRD+GLVVIG
Sbjct: 32  PPLDGAVEWVNSKPLSVEQLRGKVVLVDFWTYSCINCIRTIPYVRAWAEKYRDQGLVVIG 91

Query: 111 VHTPEFPFEHSASNVQAALKRHGILYPVAQDNNSQTWNAYRNQYWPAQYVIDQNGKIVFQ 170
           VH PEF FE   +NV++A+    I YPVA DN+   W A+ N YWPA Y ID  G+I   
Sbjct: 92  VHAPEFAFEKRIANVRSAVTDFDIRYPVAIDNDFAIWRAFGNSYWPAHYFIDAEGRIRHH 151

Query: 171 HAGEGQYDEIDRTVARLL 188
           H GEG Y   +R +  LL
Sbjct: 152 HFGEGDYARSERVIQELL 169


>MT2942_2 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins MtC
           Mycobacterium tuberculosis CDC1551
          Length = 296

 Score =  156 bits (395), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 71/143 (49%), Positives = 89/143 (62%), Gaps = 3/143 (2%)

Query: 50  APEFAGISNWFNS---KPLKLADLRGKVVLVDFWTYGCVNCVNTLPHVTQLYSKYRDRGL 106
           AP+  GI+ W N+   KP+ L  LRGKVVL+DFW Y C+NC   +PHV   Y  Y+D GL
Sbjct: 1   APDLKGITGWLNTPGNKPIDLKSLRGKVVLIDFWAYSCINCQRAIPHVVGWYQAYKDSGL 60

Query: 107 VVIGVHTPEFPFEHSASNVQAALKRHGILYPVAQDNNSQTWNAYRNQYWPAQYVIDQNGK 166
            VIGVHTPE+ FE    NV       GI YP+A DNN  TW  YRN+YWPA+Y+ID  G 
Sbjct: 61  AVIGVHTPEYAFEKVPGNVAKGAANLGISYPIALDNNYATWTNYRNRYWPAEYLIDATGT 120

Query: 167 IVFQHAGEGQYDEIDRTVARLLD 189
           +     GEG Y+  +  V +LL+
Sbjct: 121 VRHIKFGEGDYNVTETLVRQLLN 143


>Rv2874_2 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Mtu
           Mycobacterium tuberculosis H37Rv
          Length = 294

 Score =  152 bits (385), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 69/141 (48%), Positives = 87/141 (61%), Gaps = 3/141 (2%)

Query: 52  EFAGISNWFNS---KPLKLADLRGKVVLVDFWTYGCVNCVNTLPHVTQLYSKYRDRGLVV 108
           +  GI+ W N+   KP+ L  LRGKVVL+DFW Y C+NC   +PHV   Y  Y+D GL V
Sbjct: 1   DLKGITGWLNTPGNKPIDLKSLRGKVVLIDFWAYSCINCQRAIPHVVGWYQAYKDSGLAV 60

Query: 109 IGVHTPEFPFEHSASNVQAALKRHGILYPVAQDNNSQTWNAYRNQYWPAQYVIDQNGKIV 168
           IGVHTPE+ FE    NV       GI YP+A DNN  TW  YRN+YWPA+Y+ID  G + 
Sbjct: 61  IGVHTPEYAFEKVPGNVAKGAANLGISYPIALDNNYATWTNYRNRYWPAEYLIDATGTVR 120

Query: 169 FQHAGEGQYDEIDRTVARLLD 189
               GEG Y+  +  V +LL+
Sbjct: 121 HIKFGEGDYNVTETLVRQLLN 141


>alr1013_1 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Nos Nostoc
           sp. PCC 7120
          Length = 173

 Score =  113 bits (283), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 84/140 (60%), Gaps = 2/140 (1%)

Query: 50  APEFAGISNWFNS-KPLKLADLRGKVVLVDFWTYGCVNCVNTLPHVTQLYSKYRDRGLVV 108
           APE      W N+ +PL +  L G+VV++DFWTY C+NC++ LP +  L  KY+D  L V
Sbjct: 7   APELPQNYPWLNTEQPLSIKQLNGRVVILDFWTYCCINCLHVLPDLKYLEQKYKD-SLTV 65

Query: 109 IGVHTPEFPFEHSASNVQAALKRHGILYPVAQDNNSQTWNAYRNQYWPAQYVIDQNGKIV 168
           IGVH+ +F  E    N++ A+ R+ I +PV  D + + W  Y  + WP   VID  G ++
Sbjct: 66  IGVHSAKFDNEQETENIRQAILRYDIEHPVLVDKDFRVWQEYAVRAWPTLMVIDPKGYVI 125

Query: 169 FQHAGEGQYDEIDRTVARLL 188
              +GEG  D++D+ + +++
Sbjct: 126 GYVSGEGNRDKLDQLITQVI 145


>BH2664 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bha
           Bacillus halodurans
          Length = 149

 Score = 88.2 bits (217), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 74/147 (50%), Gaps = 2/147 (1%)

Query: 42  MTTEQSQTAPEFAGISNWFNSKPLKLADLRGKVVLVDFWTYGCVNCVNTLPHVTQLYSKY 101
           M  +     PE  G + W N +  K +DL+ K  L+ FW+  C  C   +P+V +   KY
Sbjct: 1   MALKLRSQMPELEGATAWLNGEVQK-SDLQDKPTLIHFWSISCGLCKEAMPNVNEFRDKY 59

Query: 102 RDRGLVVIGVHTPEFPFEHSASNVQAALKRHGILYPVAQDNNSQTWNAYRNQYWPAQYVI 161
           +D+ L VI VH P    +     ++   + HGI  P+  D+  +  +A+ N+Y PA YV 
Sbjct: 60  KDQ-LHVIAVHMPRSEKDLDLEQIKQVAEEHGITQPIFVDSQHKLTDAFENEYVPAYYVF 118

Query: 162 DQNGKIVFQHAGEGQYDEIDRTVARLL 188
           D+ G++    AG G    + + V R+L
Sbjct: 119 DEEGQLRHFQAGGGGMKMLTKRVNRVL 145