BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0094.0046.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 82 3e-15 BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superf... 73 1e-12 AF0367 [GEPR] COG0477 Permeases of the major facilitator superfa... 67 9e-11 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 81.6 bits (200), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 103/404 (25%), Positives = 177/404 (43%), Gaps = 33/404 (8%) Query: 16 YEGWRIVVVCFL--LATFGWGLGF--YGQSVYVAELHKLHGWPASLISSGTTFFYLFGAA 71 + GW IV V FL LA G L F + Q + E G SLIS T F ++G + Sbjct: 6 HYGWIIVAVTFLTFLAVQGVRLSFGAFVQP-WETEFSMDRG-SISLIS--TLSFIVYGIS 61 Query: 72 LVAFVSEAIKAFGARSCLIAGTFAMAIAAVAIGEVREPWQLYL-------ANALLAFGWA 124 + + + GAR L T + ++ V +PW L++ A A Sbjct: 62 -QPLIGKLVDRLGARFILSCSTLLVGVSFVLTTMATQPWHLFILYGVVVSIGVGGASNVA 120 Query: 125 GTSLGIITNTLGLWFDKKRGMAISLALNGASFGGIVGVPLLVAGIGTFGFSGAMIAAALL 184 T +ITN WF+KKRG+A + G G ++ VP + I + ++ Sbjct: 121 ATV--VITN----WFNKKRGLAFGIIEAGFGAGQMILVPGSLMLIQWLDWKATVVILGFF 174 Query: 185 LIVVMVPVILILVGRPPAHLHAVTAAAAADAP-------SATQVRARALRDIRFLSVSIA 237 L V++ P++L+L+ P+ + SAT R F + + Sbjct: 175 LAVIVFPIVLLLLRNHPSEKQVEPIGGVREEEETNTSPNSATFSNWSVFRMRPFWFLVLP 234 Query: 238 FALVLFAQVGFI-VHLI--AHLDQVIGRERATVAMALLTAMAVVGRVSFSFVIDRLNQRL 294 FA+ F G + HLI +H D + A++LL +VG + + DR + R Sbjct: 235 FAICGFTTTGLMDTHLIPLSH-DHGFSTSVTSAAVSLLAGFNIVGILLSGVIADRWSSRK 293 Query: 295 ASALSFVSQAIALAVIINVHNDVAQIAACALFGFSVGNLITLPALIVQREFDPRAFGVLV 354 L +V++A++L ++++ H+ + + LFG + L+ + F + G+++ Sbjct: 294 FLFLLYVARALSLVILVHSHDPLLLLGFAILFGLVDFATVAPTQLLATQYFKRYSIGLMI 353 Query: 355 SLLTAINQITYAFGPGVVGLLRDLSGSYSLPFYGCIGLELIAAV 398 L +Q+ A G V GLL + +GSY++ Y I + ++AA+ Sbjct: 354 GWLFLSHQVGSALGAYVPGLLYEQTGSYTVSLYVSIVILIVAAI 397 >BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 416 Score = 73.2 bits (178), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 82/333 (24%), Positives = 151/333 (45%), Gaps = 11/333 (3%) Query: 76 VSEAIKAFGARSCLIAGTFAMAIAAVAIGEVREPWQLYLANALLAFGWAGTSLGIITNTL 135 + + +GAR+ L ++ V PWQL+L L G + + + L Sbjct: 64 IGRLVDKWGARAVLAWSALLTGVSIFLTYLVTSPWQLFLLYGLGVSLGVGGASNVAASVL 123 Query: 136 GL-WFDKKRGMAISLALNGASFGGIVGVPLLVAGIGTFGFSGAMIAAALLLIVVMVPVIL 194 + WF KKRG+A + G G ++ VP + I F + ++ LLLIV++ P L Sbjct: 124 VVNWFSKKRGLAFGIMEAGFGAGQMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVFPAAL 183 Query: 195 ILVGRPPAHLHA-----VTAAAAADAPSATQVRARALRDIR-FLSVSIAFALVLFAQVGF 248 +++ P+ + + A+ AP T + + +R F + F + F VG Sbjct: 184 LMLRNNPSEKNTEPIGGLAASEKETAPKTTALSVAGMFRMRQFWFLIFPFLICGFTTVGL 243 Query: 249 I-VHLI--AHLDQVIGRERATVAMALLTAMAVVGRVSFSFVIDRLNQRLASALSFVSQAI 305 + HLI +H D + A++LL + G + V DR + R + + +A+ Sbjct: 244 MDTHLIPFSH-DHGFSTTVTSAAVSLLAGFNIAGILLSGIVADRWSSRKILCILYAVRAL 302 Query: 306 ALAVIINVHNDVAQIAACALFGFSVGNLITLPALIVQREFDPRAFGVLVSLLTAINQITY 365 ++ ++I H +A LFG + ++ + F + G+++ L+ +QI Sbjct: 303 SIVILIYSHEPYLLLAFAILFGLVDFATVAPTQMLATQYFQNYSIGLMIGWLSLAHQIGS 362 Query: 366 AFGPGVVGLLRDLSGSYSLPFYGCIGLELIAAV 398 A G V G++ ++G Y+L FY IG+ ++A+V Sbjct: 363 ALGAYVPGVIYTVTGEYTLAFYLSIGMLVLASV 395 >AF0367 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 397 Score = 66.6 bits (161), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 99/390 (25%), Positives = 160/390 (41%), Gaps = 17/390 (4%) Query: 19 WRIVVVCFLLATFGWGLGF-YGQSVYVAELHKLHGWPASLISSGTTFFYLFGAALVAFVS 77 W ++ FLL LG Y SV+V L GW ++ S + F L A ++ Sbjct: 5 WLVIFAGFLLNLM---LGIVYAWSVFVNPLMNTFGWSKTIASLPFSIFLLIFALMMVPAG 61 Query: 78 EAIKAFGARSCLIAGTFAMAIAAVAIG---EVREPWQLYLANALLAFGWAGTSLGIITNT 134 G R + G + + + G ++ P+ L + ++A G Sbjct: 62 RTQDRIGPRKVAMLGGVLLGVGFLLSGLIESIQSPYWLIFSYGVIAGAGCGLGYACPIPV 121 Query: 135 LGLWFDKKRGMAISLALNGASFGGIVGVPLLVAGIGTFGFSGAMIAAALLLIVVMVPVIL 194 WF ++ G+A L + G ++ PL I T+G S ++L++V V Sbjct: 122 ARKWFPERVGLATGLVVMGFGMSALIFAPLERILIDTYGISTTFYILGVILLIVAV-FAA 180 Query: 195 ILVGRPPAHLHAVTAAAAADAPSATQV----RARALRDIRFLSVSIAFALVLFAQVGFIV 250 L+ PP L AV A+ A T + LRD RF + ++F + A + I Sbjct: 181 SLLSNPP-ELPAVQASNPAKVEVVTGKPELGPSEMLRDYRFYVLWLSFFFMALAGLMVIG 239 Query: 251 HLIAHLDQVIGRER--ATVAMALLTAMAVVGRVSFSFVIDRLNQRLASALSFVSQAIALA 308 H IA Q G E A A+++L+ VGR + D++ + + + F+ Q I L Sbjct: 240 H-IAPYAQERGLEPLAAAFAVSILSVANAVGRPGAGALSDKIGRAMTMFVLFLIQGITLI 298 Query: 309 VIINVHNDVAQIAAC-ALFGFSVGNLITLPALIVQREFDPRAFGVLVSLLTAINQITYAF 367 +V + I C A+ GF+ G +L F + GV L+ + Sbjct: 299 AFPHVALTLITIYICAAIIGFNYGANFSLFPSATGDFFGTKNLGVNYGLVFTSYGVGGLV 358 Query: 368 GPGVVGLLRDLSGSYSLPFYGCIGLELIAA 397 GP + G + D++GSY + F L LIAA Sbjct: 359 GPIMAGYVFDVTGSYEIAFLVAGVLALIAA 388