BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0091.0008.p (467 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Z3566 [R] COG1090 Predicted nucleoside-diphosphate sugar epimera... 227 4e-59 ECs3188 [R] COG1090 Predicted nucleoside-diphosphate sugar epime... 227 4e-59 yfcH [R] COG1090 Predicted nucleoside-diphosphate sugar epimeras... 226 7e-59 STM2350 [R] COG1090 Predicted nucleoside-diphosphate sugar epime... 212 2e-54 YPO2778 [R] COG1090 Predicted nucleoside-diphosphate sugar epime... 207 4e-53 >Z3566 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase EcZ Escherichia coli O157:H7 EDL933 Length = 297 Score = 227 bits (579), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 122/279 (43%), Positives = 166/279 (59%), Gaps = 3/279 (1%) Query: 186 LVASLTISGHQVIALIRNPAKAD-MLPPPVTLITSLDQLPADSGIDAIVNLAGEPIGNGL 244 L+ L GHQ+ + RNP KA +L P VTL L +GIDA++NLAGEPI + Sbjct: 16 LIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGIDAVINLAGEPIADKR 75 Query: 245 WTEAKRRKIIASRIDMTSDVIKLIARLERKPSVLVSGSAIGWYGLWQDQVLTESAKSHAC 304 WT ++ ++ SR ++T ++ LI + PSVL+SGSA G+YG + V+TE H Sbjct: 76 WTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNK 135 Query: 305 FSHELCEAWENAAKPAADHGVRVAYLRIGLVVGTDGGFITRMLTPFEFGLGGPLGSGKQW 364 F+H+LC WE A A RV LR G+V+ DGG + +ML PF GLGGP+GSG+Q+ Sbjct: 136 FTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQY 195 Query: 365 MSWIERDDLVRLIAHVIARPELSGPVNATAPIPVTNTKFTEELGRRLHRPAIFRVPAALL 424 ++WI DD+V I ++ EL GP N +P P+ N +F LG LHRPAI RVPA + Sbjct: 196 LAWIHIDDMVNGILWLLDN-ELRGPFNMVSPYPIRNEQFAHALGHALHRPAILRVPATAI 254 Query: 425 RAVGGDFADELLLGGQRVLPNKALSNGFVFRHETLRSAF 463 R + G+ + L+LGGQR LP + GF FR L A Sbjct: 255 RLLMGE-SSVLVLGGQRALPKRLEEAGFAFRWYDLEEAL 292 >ECs3188 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase Ecs Escherichia coli O157:H7 Length = 297 Score = 227 bits (579), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 122/279 (43%), Positives = 166/279 (59%), Gaps = 3/279 (1%) Query: 186 LVASLTISGHQVIALIRNPAKAD-MLPPPVTLITSLDQLPADSGIDAIVNLAGEPIGNGL 244 L+ L GHQ+ + RNP KA +L P VTL L +GIDA++NLAGEPI + Sbjct: 16 LIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGIDAVINLAGEPIADKR 75 Query: 245 WTEAKRRKIIASRIDMTSDVIKLIARLERKPSVLVSGSAIGWYGLWQDQVLTESAKSHAC 304 WT ++ ++ SR ++T ++ LI + PSVL+SGSA G+YG + V+TE H Sbjct: 76 WTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNK 135 Query: 305 FSHELCEAWENAAKPAADHGVRVAYLRIGLVVGTDGGFITRMLTPFEFGLGGPLGSGKQW 364 F+H+LC WE A A RV LR G+V+ DGG + +ML PF GLGGP+GSG+Q+ Sbjct: 136 FTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQY 195 Query: 365 MSWIERDDLVRLIAHVIARPELSGPVNATAPIPVTNTKFTEELGRRLHRPAIFRVPAALL 424 ++WI DD+V I ++ EL GP N +P P+ N +F LG LHRPAI RVPA + Sbjct: 196 LAWIHIDDMVNGILWLLDN-ELRGPFNMVSPYPIRNEQFAHALGHALHRPAILRVPATAI 254 Query: 425 RAVGGDFADELLLGGQRVLPNKALSNGFVFRHETLRSAF 463 R + G+ + L+LGGQR LP + GF FR L A Sbjct: 255 RLLMGE-SSVLVLGGQRALPKRLEEAGFAFRWYDLEEAL 292 >yfcH [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase Eco Escherichia coli K12 Length = 297 Score = 226 bits (577), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 122/279 (43%), Positives = 166/279 (59%), Gaps = 3/279 (1%) Query: 186 LVASLTISGHQVIALIRNPAKAD-MLPPPVTLITSLDQLPADSGIDAIVNLAGEPIGNGL 244 L+ L GHQ+ + RNP KA +L P VTL L +G+DA++NLAGEPI + Sbjct: 16 LIPRLLELGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNGVDAVINLAGEPIADKR 75 Query: 245 WTEAKRRKIIASRIDMTSDVIKLIARLERKPSVLVSGSAIGWYGLWQDQVLTESAKSHAC 304 WT ++ ++ SR ++T ++ LI + PSVL+SGSA G+YG + V+TE H Sbjct: 76 WTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNE 135 Query: 305 FSHELCEAWENAAKPAADHGVRVAYLRIGLVVGTDGGFITRMLTPFEFGLGGPLGSGKQW 364 F+H+LC WE A A RV LR G+V+ DGG + +ML PF GLGGP+GSG+Q+ Sbjct: 136 FTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQY 195 Query: 365 MSWIERDDLVRLIAHVIARPELSGPVNATAPIPVTNTKFTEELGRRLHRPAIFRVPAALL 424 ++WI DD+V I ++ EL GP N +P PV N +F LG LHRPAI RVPA + Sbjct: 196 LAWIHIDDMVNGILWLLDN-ELRGPFNMVSPYPVRNEQFAHALGHALHRPAILRVPATAI 254 Query: 425 RAVGGDFADELLLGGQRVLPNKALSNGFVFRHETLRSAF 463 R + G+ + L+LGGQR LP + GF FR L A Sbjct: 255 RLLMGE-SSVLVLGGQRALPKRLEEAGFAFRWYDLEEAL 292 >STM2350 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase Sty Salmonella typhimurium LT2 Length = 297 Score = 212 bits (539), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 118/283 (41%), Positives = 163/283 (57%), Gaps = 3/283 (1%) Query: 186 LVASLTISGHQVIALIRNPAKA-DMLPPPVTLITSLDQLPADSGIDAIVNLAGEPIGNGL 244 L+ L GHQV + RNP A +L VTL L + + IDAI+NLAGEPI + Sbjct: 16 LIPRLLTLGHQVTVVTRNPDNARQILDSRVTLWKGLAEREHLNEIDAIINLAGEPIADKR 75 Query: 245 WTEAKRRKIIASRIDMTSDVIKLIARLERKPSVLVSGSAIGWYGLWQDQVLTESAKSHAC 304 WT ++ ++ SR +T ++ LI PSVL+SGSA G+YG D V+TE H Sbjct: 76 WTSQQKERLCQSRWAITQKLVDLIHASATPPSVLISGSATGYYGDLGDVVVTEDEPPHNE 135 Query: 305 FSHELCEAWENAAKPAADHGVRVAYLRIGLVVGTDGGFITRMLTPFEFGLGGPLGSGKQW 364 F+H+LC WE A A RV LR G+V+ GG + +M+ PF GLGGP+G+G+Q+ Sbjct: 136 FTHKLCARWEQIACRAQSDQTRVCLLRTGVVLAPQGGILGKMVPPFRLGLGGPVGNGRQY 195 Query: 365 MSWIERDDLVRLIAHVIARPELSGPVNATAPIPVTNTKFTEELGRRLHRPAIFRVPAALL 424 ++WI DD+V I ++ +L GP N +P PV N F LGR L RPAI R+PA + Sbjct: 196 LAWIHIDDMVNGILWLLDN-DLRGPFNMVSPYPVHNEHFAHALGRALRRPAIIRIPATAI 254 Query: 425 RAVGGDFADELLLGGQRVLPNKALSNGFVFRHETLRSAFDAIL 467 R + G+ + L+LGGQR LP + + GF FR L A ++ Sbjct: 255 RLLMGE-SSVLVLGGQRALPKRLEAAGFAFRWYDLEEALADVI 296 >YPO2778 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase Ype Yersinia pestis Length = 302 Score = 207 bits (527), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 114/283 (40%), Positives = 160/283 (56%), Gaps = 2/283 (0%) Query: 186 LVASLTISGHQVIALIRNPAKAD-MLPPPVTLITSLDQLPADSGIDAIVNLAGEPIGNGL 244 L L GHQ+ AL R+ +A+ +L VT +LD + DA++NLAGEPI Sbjct: 16 LTPFLLSQGHQITALTRSLQRANNLLGQQVTYWPTLDDQEDLNSFDAVINLAGEPIAEKR 75 Query: 245 WTEAKRRKIIASRIDMTSDVIKLIARLERKPSVLVSGSAIGWYGLWQDQVLTESAKSHAC 304 WT ++ + SR +T + LI + P+V +SGSA+G+YG ++TE H Sbjct: 76 WTSQQKEILCQSRWQITERLATLINASSQPPTVFISGSAVGFYGDQGQALVTEEEPPHDE 135 Query: 305 FSHELCEAWENAAKPAADHGVRVAYLRIGLVVGTDGGFITRMLTPFEFGLGGPLGSGKQW 364 F+H+LCE WEN A A RV LR G+V+ +GG + +ML F GLGGP+G G+Q+ Sbjct: 136 FTHQLCERWENLALAAESSHTRVCLLRTGVVLAPEGGALAKMLPLFRLGLGGPMGDGRQY 195 Query: 365 MSWIERDDLVRLIAHVIARPELSGPVNATAPIPVTNTKFTEELGRRLHRPAIFRVPAALL 424 + WI +D+V+ I +++ L GP N AP PV N +FT L L RPA R PAA + Sbjct: 196 LPWIHLEDMVQGIYYLLTTHNLRGPFNMVAPYPVHNEQFTATLADVLDRPAAIRTPAAAI 255 Query: 425 RAVGGDFADELLLGGQRVLPNKALSNGFVFRHETLRSAFDAIL 467 R + G+ A L+LGGQR LP + GF FR+ L A +L Sbjct: 256 RLLMGESAI-LVLGGQRALPKRLEEAGFGFRYYELEDALRDVL 297