BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0090.0022.p         (297 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Rv2456c [GEPR] COG0477 Permeases of the major facilitator superf...   150   3e-36
MT2531 [GEPR] COG0477 Permeases of the major facilitator superfa...   150   3e-36
AGc2694 [GEPR] COG0477 Permeases of the major facilitator superf...    86   1e-16

>Rv2456c [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu
           Mycobacterium tuberculosis H37Rv
          Length = 418

 Score =  150 bits (380), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 96/278 (34%), Positives = 149/278 (53%), Gaps = 2/278 (0%)

Query: 22  RGLDWFIFFLADVQTGFGPFVAVYLT-TQKWTQVEIGFVLSIGGIIGLLGQMPGGAIVDA 80
           R LD   F LADV+ G GP++++YL     W Q  IGFV+++GGI  ++ Q P GA+VD 
Sbjct: 14  RALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDR 73

Query: 81  ARSERVVAGCAVAAIGASALAYALWPIFPVVTLAATLHALASCVLGPAIAAISLGLVGPL 140
             ++R +       + A+A+A  L+     +++   +  +AS V  PA+AAI+LG VGP 
Sbjct: 74  TTAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQ 133

Query: 141 AIGERLGRNARFASLGSGSAAALMGACGYLLSSRSVFLVTFILAIPTLLSLARIREREID 200
               R+GRN  F   G+ SAA   GA  Y      VF V   +A+ ++L+  RI    +D
Sbjct: 134 FFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVD 193

Query: 201 IAQAHG-EVKREVPDKRATSVVGLVRQRPLLIFAGAMMLFQLANAAMLPLMAGVVTTRSS 259
              A G +     P  + +    L   R L+IF  A++ F  ANAAMLPL+  ++   + 
Sbjct: 194 HDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNR 253

Query: 260 QWAPVLIAACIIVPQAIVALCSPSVGRKAQAWGRRPLL 297
                L+++CI+  Q ++   +  VG +A AWGR+P+ 
Sbjct: 254 DEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIF 291


>MT2531 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC
           Mycobacterium tuberculosis CDC1551
          Length = 418

 Score =  150 bits (380), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 96/278 (34%), Positives = 149/278 (53%), Gaps = 2/278 (0%)

Query: 22  RGLDWFIFFLADVQTGFGPFVAVYLT-TQKWTQVEIGFVLSIGGIIGLLGQMPGGAIVDA 80
           R LD   F LADV+ G GP++++YL     W Q  IGFV+++GGI  ++ Q P GA+VD 
Sbjct: 14  RALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDR 73

Query: 81  ARSERVVAGCAVAAIGASALAYALWPIFPVVTLAATLHALASCVLGPAIAAISLGLVGPL 140
             ++R +       + A+A+A  L+     +++   +  +AS V  PA+AAI+LG VGP 
Sbjct: 74  TTAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQ 133

Query: 141 AIGERLGRNARFASLGSGSAAALMGACGYLLSSRSVFLVTFILAIPTLLSLARIREREID 200
               R+GRN  F   G+ SAA   GA  Y      VF V   +A+ ++L+  RI    +D
Sbjct: 134 FFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVD 193

Query: 201 IAQAHG-EVKREVPDKRATSVVGLVRQRPLLIFAGAMMLFQLANAAMLPLMAGVVTTRSS 259
              A G +     P  + +    L   R L+IF  A++ F  ANAAMLPL+  ++   + 
Sbjct: 194 HDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNR 253

Query: 260 QWAPVLIAACIIVPQAIVALCSPSVGRKAQAWGRRPLL 297
                L+++CI+  Q ++   +  VG +A AWGR+P+ 
Sbjct: 254 DEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIF 291


>AGc2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu
           Agrobacterium tumefaciens strain C58 (Cereon)
          Length = 498

 Score = 85.5 bits (210), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 71/233 (30%), Positives = 114/233 (48%), Gaps = 21/233 (9%)

Query: 29  FFLADVQTGFGPFVAVYLTTQKWTQVEIGFVLSIGGIIGLLGQMPGGAIVDAARSERVVA 88
           FFLAD + G GPF+  +L TQ W+ + +G + ++GG++GLL     GA+VD    +R++ 
Sbjct: 110 FFLADARDGLGPFLDAFLATQGWSSLSLGMIATVGGLVGLLATPLCGALVDGTTWKRMLI 169

Query: 89  GCAVAAIGASALAYALWPIFPVVTLAATLHALASCVLGPAIAAISLGLVGPLAIGERLGR 148
              V  +   AL   ++P   +V     + A+   V+GPA+A ++LGLVG      ++ R
Sbjct: 170 AIPVVLVTIGALITLIFPDAWIVWTGQIMTAVVGAVVGPALAGLTLGLVGERLFSNQISR 229

Query: 149 N------ARFASLGSGSAA----ALMGACGYLLSSRSVFLVTFILAIPTLLSLARIRERE 198
           N        FASL +         + G  G +L + +  LV      P     ARI  + 
Sbjct: 230 NEFWNHGGNFASLFATYVVVTFFGMNGIIGLMLLTAAGALVATAAIDP-----ARIDHK- 283

Query: 199 IDIAQAHGEVKREVPDKRATSVVGLVRQRPLLIFAGAMMLFQLANAAMLPLMA 251
             +A+   E K E P     +V  L+ +R L+  A  +++F   NA M  L+A
Sbjct: 284 --VARGLAEDKGE-PGPSGINV--LLHERGLIFLAIILLVFHFGNAPMGRLIA 331