BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0090.0002.p (467 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 423 e-118 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 401 e-111 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 401 e-111 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 401 e-111 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 392 e-108 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 423 bits (1087), Expect = e-118, Method: Compositional matrix adjust. Identities = 220/452 (48%), Positives = 298/452 (65%), Gaps = 6/452 (1%) Query: 18 DGLPWERRRWAVAAIFTALAMASLDTAIANIALPAIASDLHVSPAEVVWVVNVYQIALVA 77 DGLP +R A+ I + MA LD IAN+ALP IA DL+ SPA +WVVN YQ+A+ Sbjct: 7 DGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITI 66 Query: 78 TLLPLGALGEIVGHQRIYLGGLLLFTLASLGCALAWSLPSLLVARTLQGLGASGLMSVNT 137 +LL + +LG+I+G++R+Y GLL+F++ SL CAL+ SL +L AR LQG GA+ LMSVNT Sbjct: 67 SLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNT 126 Query: 138 ALVRFVYPSRMHGRGFGHNALVVATAFTLGPTIASGILALGPWPWLFAVNIPFGVVALLI 197 AL+R +YP GRG G N L+VA + GP+IA+ +L++ W WLFA+N+P G++A + Sbjct: 127 ALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAWCL 186 Query: 198 GMKTLP--TTPRATHAFDFTGAALACACLGLFIIGIGSAAHKAAPALVIAELVGALVIGW 255 G+K LP T + FD T L GL I I + +PA++ A++V L+IG+ Sbjct: 187 GIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVALLLIGF 246 Query: 256 ILTRRHADHPAPMLPIDLFRRPIFALSAATAVCSFAVQGLAFVSLPFYFEDILHRSQVET 315 RR P+LP+DL R PIFALS T++ SFA Q LA VSLPF+ + +L R +V T Sbjct: 247 FFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVAT 306 Query: 316 GFFMTPWPLVVAFMAPIDGRLSDRYPAGILGGIGMLLLGLGMVLLATLPAEPSVANIVWR 375 G +TPWPL +API GRL +RY AG+LGGIG+ + G+ LLA LPA PS +I+WR Sbjct: 307 GLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWR 366 Query: 376 TMICGIGFGFFQTPNMKAIMSSAPSHRSGSASGIVATARLTGQTTGAALAALCFALADRE 435 ++CG GFG FQTPN I+S+AP HRSG ASG++ TARL GQT+GAAL AL F + Sbjct: 367 MILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVALMFNMFSTN 426 Query: 436 GATVALALGAGFAALGSVMSFLRLAVASPQKS 467 G +L L FA++ +++S LR+ QKS Sbjct: 427 GTHASLILAGCFASIAALVSLLRVT----QKS 454 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 401 bits (1031), Expect = e-111, Method: Compositional matrix adjust. Identities = 207/428 (48%), Positives = 278/428 (64%), Gaps = 6/428 (1%) Query: 18 DGLPWERRRWAVAAIFTALAMASLDTAIANIALPAIASDLHVSPAEVVWVVNVYQIALVA 77 DGLP +R A+ I ++MA LD AIAN+ALP IA+DLH +PA +WVVN YQIA+V Sbjct: 44 DGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVI 103 Query: 78 TLLPLGALGEIVGHQRIYLGGLLLFTLASLGCALAWSLPSLLVARTLQGLGASGLMSVNT 137 +LL LG++ G++RIY GL++F L+SL CAL+ SL L +AR +QG G + LMSVNT Sbjct: 104 SLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNT 163 Query: 138 ALVRFVYPSRMHGRGFGHNALVVATAFTLGPTIASGILALGPWPWLFAVNIPFGVVALLI 197 AL+R +YP R GRG G N+ +VA + GPTIA+ IL++ W WLF +N+P G++ALL+ Sbjct: 164 ALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLL 223 Query: 198 GMKTLPTTPRATHA----FDFTGAALACACLGLFIIGIGSAAHKAAPALVIAELVGALVI 253 M+ LP P + A FD A + GL I + A + L+ AELV +V+ Sbjct: 224 AMRFLP--PNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVV 281 Query: 254 GWILTRRHADHPAPMLPIDLFRRPIFALSAATAVCSFAVQGLAFVSLPFYFEDILHRSQV 313 G RR P P+LP+DL R P+F+LS T+VCSF Q LA VSLPFY + +L RS+V Sbjct: 282 GIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEV 341 Query: 314 ETGFFMTPWPLVVAFMAPIDGRLSDRYPAGILGGIGMLLLGLGMVLLATLPAEPSVANIV 373 ETG +TPWPL MAP+ G L +R AG+LG +G+ ++ G+ L LPA P+ NI+ Sbjct: 342 ETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINII 401 Query: 374 WRTMICGIGFGFFQTPNMKAIMSSAPSHRSGSASGIVATARLTGQTTGAALAALCFALAD 433 W ++CG GFG FQ+PN I++SAP RSG ASG++ TARL GQ++GAAL AL Sbjct: 402 WPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQFG 461 Query: 434 REGATVAL 441 G V+L Sbjct: 462 DNGTHVSL 469 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 401 bits (1030), Expect = e-111, Method: Compositional matrix adjust. Identities = 207/428 (48%), Positives = 278/428 (64%), Gaps = 6/428 (1%) Query: 18 DGLPWERRRWAVAAIFTALAMASLDTAIANIALPAIASDLHVSPAEVVWVVNVYQIALVA 77 DGLP +R A+ I ++MA LD AIAN+ALP IA+DLH +PA +WVVN YQIA+V Sbjct: 44 DGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVI 103 Query: 78 TLLPLGALGEIVGHQRIYLGGLLLFTLASLGCALAWSLPSLLVARTLQGLGASGLMSVNT 137 +LL LG++ G++RIY GL++F L+SL CAL+ SL L +AR +QG G + LMSVNT Sbjct: 104 SLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSVNT 163 Query: 138 ALVRFVYPSRMHGRGFGHNALVVATAFTLGPTIASGILALGPWPWLFAVNIPFGVVALLI 197 AL+R +YP R GRG G N+ +VA + GPTIA+ IL++ W WLF +N+P G++ALL+ Sbjct: 164 ALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLL 223 Query: 198 GMKTLPTTPRATHA----FDFTGAALACACLGLFIIGIGSAAHKAAPALVIAELVGALVI 253 M+ LP P + A FD A + GL I + A + L+ AELV +V+ Sbjct: 224 AMRFLP--PNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVV 281 Query: 254 GWILTRRHADHPAPMLPIDLFRRPIFALSAATAVCSFAVQGLAFVSLPFYFEDILHRSQV 313 G RR P P+LP+DL R P+F+LS T+VCSF Q LA VSLPFY + +L RS+V Sbjct: 282 GIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEV 341 Query: 314 ETGFFMTPWPLVVAFMAPIDGRLSDRYPAGILGGIGMLLLGLGMVLLATLPAEPSVANIV 373 ETG +TPWPL MAP+ G L +R AG+LG +G+ ++ G+ L LPA P+ NI+ Sbjct: 342 ETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINII 401 Query: 374 WRTMICGIGFGFFQTPNMKAIMSSAPSHRSGSASGIVATARLTGQTTGAALAALCFALAD 433 W ++CG GFG FQ+PN I++SAP RSG ASG++ TARL GQ++GAAL AL Sbjct: 402 WPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQFG 461 Query: 434 REGATVAL 441 G V+L Sbjct: 462 DNGTHVSL 469 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 401 bits (1030), Expect = e-111, Method: Compositional matrix adjust. Identities = 207/428 (48%), Positives = 278/428 (64%), Gaps = 6/428 (1%) Query: 18 DGLPWERRRWAVAAIFTALAMASLDTAIANIALPAIASDLHVSPAEVVWVVNVYQIALVA 77 DGLP +R A+ I ++MA LD AIAN+ALP IA+DLH +PA +WVVN YQIA+V Sbjct: 44 DGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVI 103 Query: 78 TLLPLGALGEIVGHQRIYLGGLLLFTLASLGCALAWSLPSLLVARTLQGLGASGLMSVNT 137 +LL LG++ G++RIY GL++F L+SL CAL+ SL L +AR +QG G + LMSVNT Sbjct: 104 SLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSVNT 163 Query: 138 ALVRFVYPSRMHGRGFGHNALVVATAFTLGPTIASGILALGPWPWLFAVNIPFGVVALLI 197 AL+R +YP R GRG G N+ +VA + GPTIA+ IL++ W WLF +N+P G++ALL+ Sbjct: 164 ALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLL 223 Query: 198 GMKTLPTTPRATHA----FDFTGAALACACLGLFIIGIGSAAHKAAPALVIAELVGALVI 253 M+ LP P + A FD A + GL I + A + L+ AELV +V+ Sbjct: 224 AMRFLP--PNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVV 281 Query: 254 GWILTRRHADHPAPMLPIDLFRRPIFALSAATAVCSFAVQGLAFVSLPFYFEDILHRSQV 313 G RR P P+LP+DL R P+F+LS T+VCSF Q LA VSLPFY + +L RS+V Sbjct: 282 GIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEV 341 Query: 314 ETGFFMTPWPLVVAFMAPIDGRLSDRYPAGILGGIGMLLLGLGMVLLATLPAEPSVANIV 373 ETG +TPWPL MAP+ G L +R AG+LG +G+ ++ G+ L LPA P+ NI+ Sbjct: 342 ETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINII 401 Query: 374 WRTMICGIGFGFFQTPNMKAIMSSAPSHRSGSASGIVATARLTGQTTGAALAALCFALAD 433 W ++CG GFG FQ+PN I++SAP RSG ASG++ TARL GQ++GAAL AL Sbjct: 402 WPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQFG 461 Query: 434 REGATVAL 441 G V+L Sbjct: 462 DNGTHVSL 469 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 392 bits (1006), Expect = e-108, Method: Compositional matrix adjust. Identities = 215/448 (47%), Positives = 289/448 (64%), Gaps = 10/448 (2%) Query: 18 DGLPWERRRWAVAAIFTALAMASLDTAIANIALPAIASDLHVSPAEVVWVVNVYQIALVA 77 DGLP +R A+ I ++MA LD AIAN+ALP IA+DLH SPA +W+VN YQIA+V Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 78 TLLPLGALGEIVGHQRIYLGGLLLFTLASLGCALAWSLPSLLVARTLQGLGASGLMSVNT 137 +LL L LG++ G+ RIY GL++F L+SL CAL+ SL L +AR QG G + LMSVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 138 ALVRFVYPSRMHGRGFGHNALVVATAFTLGPTIASGILALGPWPWLFAVNIPFGVVALLI 197 AL+R +YP R GRG G N+ +VA + GPTIA+ IL++ W WLF +N+P G++AL++ Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 198 GMKTLP------TTPRATHAFDFTGAALACACLGLFIIGIGSAAHKAAPALVIAELVGAL 251 ++ LP T PR FD A + GL I + A + L+ AEL+ + Sbjct: 187 AIRFLPANIAHDTKPR----FDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLV 242 Query: 252 VIGWILTRRHADHPAPMLPIDLFRRPIFALSAATAVCSFAVQGLAFVSLPFYFEDILHRS 311 V+G+ RR P P+LPIDL R P+F+LS T++CSF Q LA VSLPFY + +L RS Sbjct: 243 VVGFFFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLGRS 302 Query: 312 QVETGFFMTPWPLVVAFMAPIDGRLSDRYPAGILGGIGMLLLGLGMVLLATLPAEPSVAN 371 +VETG +TPWPL MAP+ G L +R AG+LG +GM+++ G+ L LPA PS N Sbjct: 303 EVETGLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMAAGLFALVMLPASPSDLN 362 Query: 372 IVWRTMICGIGFGFFQTPNMKAIMSSAPSHRSGSASGIVATARLTGQTTGAALAALCFAL 431 I+W ++CG GFG FQ+PN I++SAP RSG ASG++ TARL GQ+TGAAL AL Sbjct: 363 IIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSTGAALVALMLNQ 422 Query: 432 ADREGATVALALGAGFAALGSVMSFLRL 459 G ++L A A L +V+S LR+ Sbjct: 423 FGDSGTHLSLLAAAILAILAAVVSGLRI 450