BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0087.0045.p (241 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr3848 [IQR] COG1028 Dehydrogenases with different specificitie... 374 e-104 SMc03878 [IQR] COG1028 Dehydrogenases with different specificiti... 368 e-102 AGc5024 [IQR] COG1028 Dehydrogenases with different specificitie... 323 2e-88 CC0511 [IQR] COG1028 Dehydrogenases with different specificities... 310 2e-84 RP035 [IQR] COG1028 Dehydrogenases with different specificities ... 254 9e-68 >mlr3848 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 241 Score = 374 bits (961), Expect = e-104, Method: Compositional matrix adjust. Identities = 181/239 (75%), Positives = 206/239 (86%) Query: 1 MARVALVTGGTRGIGAAISKALKAAGYKVAASYAGNDAAAEKFKAESGIPVYKWDVASFD 60 M +VA+VTGG+RGIGAAIS ALK+AGY VAA+YAGND AA KFKAE+GIPVYKW VA +D Sbjct: 1 MTKVAIVTGGSRGIGAAISIALKSAGYSVAANYAGNDEAAAKFKAETGIPVYKWSVADYD 60 Query: 61 ACAAGVKQVEADLGPVDVLVNNAGITKDTAFHKMTVEQWNAVINTNLGSLFNMTRQVIEG 120 ACAAG+KQVEADLGPV VLVNNAGIT+D FHK+T +QW VI+TNL +FNMT + G Sbjct: 61 ACAAGIKQVEADLGPVSVLVNNAGITRDAMFHKITRDQWKEVIDTNLSGVFNMTHPLWNG 120 Query: 121 MRARKFGRVISISSINGQKGQFGQVNYSAAKAGDIGFTKALALENAKGGITVNVICPGYI 180 MR RKFGRVI+ISSINGQKGQ GQVNYSAAKAGDIGF+KALA E A+ GITVNVICPGYI Sbjct: 121 MRDRKFGRVITISSINGQKGQAGQVNYSAAKAGDIGFSKALAQEGARAGITVNVICPGYI 180 Query: 181 NTEMVQAVPKDVLEKNVIPQIPVARLGEPEEIARAVVFLAADDAGFITGSTLTVNGGQY 239 TEMV+A+ + VL + ++PQIPV RLGEPEEIAR VVFLA+ DAGFITGST+T NGGQY Sbjct: 181 ATEMVKAIDEKVLNERILPQIPVGRLGEPEEIARCVVFLASQDAGFITGSTITANGGQY 239 >SMc03878 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 241 Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust. Identities = 177/241 (73%), Positives = 202/241 (83%) Query: 1 MARVALVTGGTRGIGAAISKALKAAGYKVAASYAGNDAAAEKFKAESGIPVYKWDVASFD 60 M+RVALVTGG+RGIGAAI ALKAAGYKVAA+YAGND A+ F+ ESGIPVYKWDV+S+ Sbjct: 1 MSRVALVTGGSRGIGAAICVALKAAGYKVAANYAGNDERAKAFEQESGIPVYKWDVSSYQ 60 Query: 61 ACAAGVKQVEADLGPVDVLVNNAGITKDTAFHKMTVEQWNAVINTNLGSLFNMTRQVIEG 120 AC G+ +VEADLGPVD+LVNNAGIT+D FHKMT EQW VI TNL +FNMT + G Sbjct: 61 ACVDGIARVEADLGPVDILVNNAGITRDAMFHKMTPEQWGEVIGTNLTGVFNMTHPLWSG 120 Query: 121 MRARKFGRVISISSINGQKGQFGQVNYSAAKAGDIGFTKALALENAKGGITVNVICPGYI 180 MR R FGR+++ISSINGQKGQ GQVNYSAAKAGD+G TKALA E A GITVN ICPGYI Sbjct: 121 MRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGITVNAICPGYI 180 Query: 181 NTEMVQAVPKDVLEKNVIPQIPVARLGEPEEIARAVVFLAADDAGFITGSTLTVNGGQYH 240 TEMV+AVP+ VL + +IPQIPV RLGEPEE+AR VVFLA+DDAGFITGST++ NGGQY Sbjct: 181 GTEMVRAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLASDDAGFITGSTISANGGQYF 240 Query: 241 A 241 A Sbjct: 241 A 241 >AGc5024 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 245 Score = 323 bits (829), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 159/241 (65%), Positives = 194/241 (80%) Query: 1 MARVALVTGGTRGIGAAISKALKAAGYKVAASYAGNDAAAEKFKAESGIPVYKWDVASFD 60 M+RVAL++GGT GIGAAI++AL+AAGY+VA +YA AE F+ E+GIP ++WDV +D Sbjct: 5 MSRVALISGGTSGIGAAIARALQAAGYRVAVNYAFTTDRAEAFQKETGIPAFQWDVRDYD 64 Query: 61 ACAAGVKQVEADLGPVDVLVNNAGITKDTAFHKMTVEQWNAVINTNLGSLFNMTRQVIEG 120 AC G+ +VE GPV+VLVNNAGIT+D FHKM+ +QW VI+TNL +FNMT V G Sbjct: 65 ACVDGITKVEETFGPVEVLVNNAGITRDAMFHKMSPQQWREVIDTNLTGVFNMTHPVWPG 124 Query: 121 MRARKFGRVISISSINGQKGQFGQVNYSAAKAGDIGFTKALALENAKGGITVNVICPGYI 180 MR R FGR+++ISSINGQKGQ GQVNYSA+KAGDIGFTKALA E A ITVN ICPGYI Sbjct: 125 MRERGFGRIVNISSINGQKGQAGQVNYSASKAGDIGFTKALAQEGASRNITVNAICPGYI 184 Query: 181 NTEMVQAVPKDVLEKNVIPQIPVARLGEPEEIARAVVFLAADDAGFITGSTLTVNGGQYH 240 TEMV+A+P+ VL + ++PQIPV RLGEPEEIAR V+FL +D+AGFITGST+T NGGQY Sbjct: 185 GTEMVRAIPEKVLAERIVPQIPVGRLGEPEEIARCVLFLVSDEAGFITGSTMTANGGQYF 244 Query: 241 A 241 A Sbjct: 245 A 245 >CC0511 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 240 Score = 310 bits (793), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 162/241 (67%), Positives = 190/241 (78%), Gaps = 1/241 (0%) Query: 1 MARVALVTGGTRGIGAAISKALKAAGYKVAASYAGNDAAAEKFKAESGIPVYKWDVASFD 60 M RVA VTGGTRGIG AI + L A G+KVAA Y+GN+AAAE E G+ V K +V F+ Sbjct: 1 MTRVAFVTGGTRGIGRAICERLIADGHKVAAGYSGNEAAAEACAKELGVMVVKGNVGVFE 60 Query: 61 ACAAGVKQVEADLGPVDVLVNNAGITKDTAFHKMTVEQWNAVINTNLGSLFNMTRQVIEG 120 C A VK+VEA+LGP+D+LVNNAGIT+D HKMT EQW+ VI N+ S FNMTR VIEG Sbjct: 61 DCQAAVKKVEAELGPIDILVNNAGITRDGMLHKMTYEQWSEVIRVNMDSAFNMTRPVIEG 120 Query: 121 MRARKFGRVISISSINGQKGQFGQVNYSAAKAGDIGFTKALALENAKGGITVNVICPGYI 180 MR R +GR+I+ISSINGQKGQ GQ NYSAAKAG IGFTKALALENAK G+TVNVICPGYI Sbjct: 121 MRDRSWGRIINISSINGQKGQMGQTNYSAAKAGLIGFTKALALENAKKGVTVNVICPGYI 180 Query: 181 NTEMVQAVPKDVLEKNVIPQIPVARLGEPEEIARAVVFLAADDAGFITGSTLTVNGGQYH 240 +TEMV AVP++VL + ++ IPV RLG EEIA V FLA + AGF+TG+TLT+NGGQY Sbjct: 181 DTEMVAAVPENVLAQ-IVAGIPVGRLGRGEEIADMVSFLAGERAGFVTGATLTLNGGQYM 239 Query: 241 A 241 A Sbjct: 240 A 240 >RP035 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rpr Rickettsia prowazekii Length = 241 Score = 254 bits (650), Expect = 9e-68, Method: Compositional matrix adjust. Identities = 127/239 (53%), Positives = 163/239 (68%), Gaps = 2/239 (0%) Query: 1 MARVALVTGGTRGIGAAISKALKAAGYKVAASYAGNDAAAEKFKAESGIPVYKWDVASFD 60 M+ +A+VTGGTRGIG A + LK V A++ N AA++ +++ GI W+VA + Sbjct: 1 MSEIAIVTGGTRGIGKATALELKNKDLTVIANFFSNYDAAKEMESKYGIRTKCWNVADLE 60 Query: 61 ACAAGVKQVEADLG-PVDVLVNNAGITKDTAFHKMTVEQWNAVINTNLGSLFNMTRQVIE 119 C V ++E + V +LVNNAGITKD H+M+ + W VIN NL S FNM+ V++ Sbjct: 61 ECKKAVNEIEEEFKKSVSILVNNAGITKDKMLHRMSNQDWTDVINVNLHSCFNMSSSVMK 120 Query: 120 GMRARKFGRVISISSINGQKGQFGQVNYSAAKAGDIGFTKALALENAKGGITVNVICPGY 179 MR + +GR+++ISSIN Q GQ GQ NYSAAKAG IGFTKALA E A ITVN I PGY Sbjct: 121 QMRNQNYGRIVNISSINAQAGQIGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGY 180 Query: 180 INTEMVQAVPKDVLEKNVIPQIPVARLGEPEEIARAVVFLAADDAGFITGSTLTVNGGQ 238 I TEMV VPKD+L K ++ IP RLG+PEEIARAV FL +AGFITG T+++NGG Sbjct: 181 IATEMVNTVPKDILTK-IVNSIPKKRLGQPEEIARAVAFLVDKNAGFITGETISINGGH 238