BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0087.0044.p (290 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00706 [GER] COG0697 Permeases of the drug/metabolite transpor... 317 3e-86 mll3550 [GER] COG0697 Permeases of the drug/metabolite transport... 275 1e-73 yddG [GER] COG0697 Permeases of the drug/metabolite transporter ... 78 2e-14 ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter... 78 2e-14 ECs2077 [GER] COG0697 Permeases of the drug/metabolite transport... 78 2e-14 >SMc00706 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 295 Score = 317 bits (811), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 162/284 (57%), Positives = 201/284 (70%) Query: 5 TATLVGLTAILMWSLLSVMTVATGAIPAFQLAAMTFAIGTAVAFASFLLRPSAFGALKQP 64 ATL+G TAILMWSLL++ T A+G +P FQL+A+ F IG+ A +P LKQP Sbjct: 4 KATLIGFTAILMWSLLALFTAASGKMPPFQLSAVCFLIGSLPGIAVLASKPERLALLKQP 63 Query: 65 LVAWVVGVGGLFGYHALYFLALRFAPPAEAGLLNYLWPLLIVLFSSLLPGERLAVHHIVG 124 WV+G+ GLFGYH LYF ALR AP EAGL+ YLWPL IV+ S+LLPGERL HH+ G Sbjct: 64 AKVWVIGIAGLFGYHFLYFTALRNAPAVEAGLIAYLWPLFIVVGSALLPGERLRWHHVAG 123 Query: 125 ALLGLAGTVLLFAGNTGAFTTEQIPGFAAAFVAAFVWASYSVMSRRLKAVPTDAVAGFCL 184 AL GL GT+L+ A N AF G+ AAF+ AF W+ YS+++RR AV TD V GFCL Sbjct: 124 ALAGLVGTILIVARNGIAFDDAYALGYGAAFLCAFTWSGYSLITRRFDAVSTDVVTGFCL 183 Query: 185 ATAVLAALVHMMVETTVWPATPLQWLAVIALGIGPVGAAFFAWDIGMKRGDIRVLGAASY 244 AT+ L+ L H+ +ETTVWP T +WLAV LG+ PVGAAF+AWD G+K GDI+ LG ASY Sbjct: 184 ATSALSFLCHLGLETTVWPETTFEWLAVAGLGLLPVGAAFYAWDYGVKNGDIQFLGVASY 243 Query: 245 ATPLLSTAFLILAGFAKPSANIAIAAILIAGGGLIAAKDMVLRK 288 A P+LST LIL GFA+PS I A +L+ GG ++AAKDM+ RK Sbjct: 244 AAPVLSTLILILFGFAEPSWRIVAACLLVTGGAVLAAKDMIFRK 287 >mll3550 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 304 Score = 275 bits (702), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 159/284 (55%), Positives = 204/284 (71%), Gaps = 1/284 (0%) Query: 6 ATLVGLTAILMWSLLSVMTVATGAIPAFQLAAMTFAIGTAVAFASFLLRPSAFGALKQPL 65 ATL+G +A+ MW+LL+++T A+G +P F L+A+TF+IGT V + L P+A + K P Sbjct: 4 ATLIGFSAVAMWALLALLTDASGKVPPFLLSAITFSIGTGVGLVARLFMPAADKSQKIPP 63 Query: 66 VAWVVGVGGLFGYHALYFLALRFAPPAEAGLLNYLWPLLIVLFSSLLPGERLAVHHIVGA 125 W++G+ GLFGYH YF ALR AP EA L+ YLWPLLIVL S+L+PGE+LA +H+VGA Sbjct: 64 QVWLIGIAGLFGYHFFYFTALRNAPAVEASLIAYLWPLLIVLGSALMPGEKLAWNHVVGA 123 Query: 126 LLGLAGTVLLFAGNTG-AFTTEQIPGFAAAFVAAFVWASYSVMSRRLKAVPTDAVAGFCL 184 LLGLAGTVL+ G AF G+A A V A +W+SYS++SRR +VPT V FC Sbjct: 124 LLGLAGTVLIVTKGGGLAFDARYAFGYAMAAVCALLWSSYSLLSRRFPSVPTSIVTWFCA 183 Query: 185 ATAVLAALVHMMVETTVWPATPLQWLAVIALGIGPVGAAFFAWDIGMKRGDIRVLGAASY 244 ATAVL+ + H+ +E TV P QWLAV+ LG+ PVGAAF+AWDIG+KRG+I+VLGAASY Sbjct: 184 ATAVLSLVCHLALEQTVLPNGAGQWLAVLGLGLMPVGAAFYAWDIGVKRGNIQVLGAASY 243 Query: 245 ATPLLSTAFLILAGFAKPSANIAIAAILIAGGGLIAAKDMVLRK 288 A PLLST LI AG A+PS I A +LI GG +AAK + LRK Sbjct: 244 AAPLLSTLVLIGAGVAEPSLRILAACVLITGGAALAAKSLFLRK 287 >yddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 293 Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 82/295 (27%), Positives = 141/295 (47%), Gaps = 24/295 (8%) Query: 1 MTTRTATLVGLTAILMWSLLS--VMTVATGAIPAFQLAAMTFAIGTAVAFASFLLRPSAF 58 MT + ATL+GL AI++WS + + V+ G P AA+ G + F F Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTV------GF 54 Query: 59 GALKQPLVAWVVGVGGLF-GYHALYFLALRFA----PPAEAGLLNYLWPLLIVLFSSLLP 113 ++Q +++ LF Y L+L +A E G++NYLWP L +LF+ L Sbjct: 55 PRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLWPSLTILFAILFN 114 Query: 114 GERLAVHHIVGALLGLAGTVLLFAGNTGAFTTEQIPG-------FAAAFVAAFVWASYSV 166 G++ + G LL L G + G+ G E I + AF+ AF+WA+Y Sbjct: 115 GQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCT 174 Query: 167 MSRRLKAVPTDAVAGFCLAT-AVLAALVHMMVETTVWPATPLQWLAVIALGIGPVGAAFF 225 ++ + A + + F L T A L + + + +TP+ + +I+ +G A+ Sbjct: 175 VTNK-YARGFNGITVFVLLTGASLWVYYFLTPQPEMIFSTPVM-IKLISAAF-TLGFAYA 231 Query: 226 AWDIGMKRGDIRVLGAASYATPLLSTAFLILAGFAKPSANIAIAAILIAGGGLIA 280 AW++G+ G++ ++ SY TP+LS+A + A S + A+++ GG L+ Sbjct: 232 AWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLC 286 >ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 82/295 (27%), Positives = 140/295 (47%), Gaps = 24/295 (8%) Query: 1 MTTRTATLVGLTAILMWSLLS--VMTVATGAIPAFQLAAMTFAIGTAVAFASFLLRPSAF 58 MT + ATL+GL AI++WS + + V+ G P AA+ G + F F Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTV------GF 54 Query: 59 GALKQPLVAWVVGVGGLF-GYHALYFLALRFA----PPAEAGLLNYLWPLLIVLFSSLLP 113 ++Q +++ LF Y L+L +A E G++NYLWP L +LF+ L Sbjct: 55 PRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFN 114 Query: 114 GERLAVHHIVGALLGLAGTVLLFAGNTGAFTTEQIPGFAA-------AFVAAFVWASYSV 166 G++ + G LL L G + G+ G E I AF+ AF+WA+Y Sbjct: 115 GQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCT 174 Query: 167 MSRRLKAVPTDAVAGFCLAT-AVLAALVHMMVETTVWPATPLQWLAVIALGIGPVGAAFF 225 ++ + A + + F L T A L + + + +TP+ + +I+ +G A+ Sbjct: 175 VTNK-YARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVM-IKLISAAF-TLGFAYA 231 Query: 226 AWDIGMKRGDIRVLGAASYATPLLSTAFLILAGFAKPSANIAIAAILIAGGGLIA 280 AW++G+ G++ ++ SY TP+LS+A + A S + A+++ GG L+ Sbjct: 232 AWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLC 286 >ECs2077 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 293 Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 82/295 (27%), Positives = 140/295 (47%), Gaps = 24/295 (8%) Query: 1 MTTRTATLVGLTAILMWSLLS--VMTVATGAIPAFQLAAMTFAIGTAVAFASFLLRPSAF 58 MT + ATL+GL AI++WS + + V+ G P AA+ G + F F Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTV------GF 54 Query: 59 GALKQPLVAWVVGVGGLF-GYHALYFLALRFA----PPAEAGLLNYLWPLLIVLFSSLLP 113 ++Q +++ LF Y L+L +A E G++NYLWP L +LF+ L Sbjct: 55 PRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFN 114 Query: 114 GERLAVHHIVGALLGLAGTVLLFAGNTGAFTTEQIPGFAA-------AFVAAFVWASYSV 166 G++ + G LL L G + G+ G E I AF+ AF+WA+Y Sbjct: 115 GQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCT 174 Query: 167 MSRRLKAVPTDAVAGFCLAT-AVLAALVHMMVETTVWPATPLQWLAVIALGIGPVGAAFF 225 ++ + A + + F L T A L + + + +TP+ + +I+ +G A+ Sbjct: 175 VTNK-YARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVM-IKLISAAF-TLGFAYA 231 Query: 226 AWDIGMKRGDIRVLGAASYATPLLSTAFLILAGFAKPSANIAIAAILIAGGGLIA 280 AW++G+ G++ ++ SY TP+LS+A + A S + A+++ GG L+ Sbjct: 232 AWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLC 286