BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0084.0018.p (384 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc279 [P] COG3454 Metal-dependent hydrolase involved in phospho... 358 1e-98 mll4974 Non COG 352 9e-97 SMb21171 [P] COG3454 Metal-dependent hydrolase involved in phosp... 349 6e-96 BMEI1106 [P] COG3454 Metal-dependent hydrolase involved in phosp... 348 2e-95 PA3374 [P] COG3454 Metal-dependent hydrolase involved in phospho... 299 6e-81 >AGc279 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 378 Score = 358 bits (919), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 194/376 (51%), Positives = 249/376 (66%), Gaps = 3/376 (0%) Query: 9 IGNARLVLADRVIEQGWVAISGGKIAEFGEGRAPEAAEDAGGDLLMPGLIELHTDHLEMH 68 + NAR+VL D +I G V I GKIA+ EG A + ED GD L+PGL+ELHTDHLE H Sbjct: 6 LSNARIVLEDDII-LGSVLIRDGKIADISEG-ASKTGEDLEGDFLIPGLVELHTDHLEQH 63 Query: 69 YVPRPKVFWNPVAAVISYDGQLATSGITTVLDSLRVWREDGAEDVDGRAGVLAAAIAAAR 128 Y PRP V W+ +AA+ ++D Q+A+SGITTV D LR+ ++ G +A AI AA Sbjct: 64 YSPRPGVIWDKIAAIQAHDAQVASSGITTVFDCLRLGSDEDGGFKKGEMREMADAIEAAA 123 Query: 129 EENLLRADHFLHLRCEVPMPDVVAEAKELIDRPDVRLMSLMDHTPGQRQFRDEVKLRDYY 188 ++N LRADH LHLRCEV DV+ ++ P VRL+SLMDH+PGQRQF+ + YY Sbjct: 124 DQNRLRADHLLHLRCEVASADVLEHFEDFETDPRVRLISLMDHSPGQRQFQSMDQYIFYY 183 Query: 189 RGKGGGMTDAQLDVLFARRFAYQKEYAVANTRAIVALAHEYRIPLASHDDTTDENVVDAV 248 + K G ++D RR A EY+ + + A + I +ASHDD T+ +V +A+ Sbjct: 184 QKKRG-LSDEAFAEFVRRRQAASAEYSAKHRDYLAASCAKRGITVASHDDATEAHVGEAI 242 Query: 249 NDRVAVAEFPTTMEAARGLHAAGIDILMGAPNVVRGGSHSGNIAAVDLANEGMLDILSSD 308 V +AEFPT++EAA+ H+AG+ +LMGAPN+VRG SHSGNIAA DLA G+LD+LSSD Sbjct: 243 GHGVKLAEFPTSVEAAKASHSAGMSVLMGAPNIVRGKSHSGNIAARDLAEIGVLDVLSSD 302 Query: 309 YIPSSLLMAALQLPRHVPAIDLASAVRTVTKTPAEAVGLNDRGEIAVGRRADLIRVHVAR 368 Y+P SLL A L V AI L+ A+R VT TPA VGL DRG IA G RADL+RVH Sbjct: 303 YVPFSLLFAPFLLADQVEAISLSEALRMVTATPARTVGLVDRGRIATGLRADLVRVHRED 362 Query: 369 DLPVVRSVWREGGRVA 384 +PV RSVWR+G RVA Sbjct: 363 GVPVARSVWRQGKRVA 378 >mll4974 Non COG Length = 379 Score = 352 bits (903), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 198/380 (52%), Positives = 252/380 (66%), Gaps = 5/380 (1%) Query: 6 DTIIGNARLVLADRVIEQGWVAISGGKIAEFGEGRAPEAAEDAGGDLLMPGLIELHTDHL 65 +T++ NAR+VLAD ++E G + + G IA G + ED GGD + PGL+ELHTDHL Sbjct: 4 ETVLSNARIVLADEIVE-GSLVLRDGFIAGIDAG-SSRIGEDMGGDYVTPGLVELHTDHL 61 Query: 66 EMHYVPRPKVFWNPVAAVISYDGQLATSGITTVLDSLRVWREDGAEDVDGRAGVLAAAIA 125 E HY PRPKV WNP+AAV+++D Q+AT+GITTVLD+LRV ++ A+ LA AI Sbjct: 62 EGHYAPRPKVRWNPIAAVLAHDAQVATAGITTVLDALRVGMDEDADLTLADIRKLADAIE 121 Query: 126 AAREENLLRADHFLHLRCEVPMPDVVAEAKELIDRPD-VRLMSLMDHTPGQRQFRDEVKL 184 + ++ LRADHFLHLRCEV PD + +A D+ D V+L SLMDH PGQRQF + ++ Sbjct: 122 DSVAQDRLRADHFLHLRCEVSAPDCL-QAFASFDQDDRVKLASLMDHAPGQRQFVN-LET 179 Query: 185 RDYYRGKGGGMTDAQLDVLFARRFAYQKEYAVANTRAIVALAHEYRIPLASHDDTTDENV 244 YY + ++D + +R A + N I A HE I LASHDD T +V Sbjct: 180 YAYYYQRKLKLSDRDFKLFCEKRMAESARNSAPNRAVIAAACHERGIVLASHDDATSGHV 239 Query: 245 VDAVNDRVAVAEFPTTMEAARGLHAAGIDILMGAPNVVRGGSHSGNIAAVDLANEGMLDI 304 +A+ V VAEFPTT EAAR AAG+ +LMGAPNV+RG SHSGN++A LA +G+LDI Sbjct: 240 DEAIEQGVRVAEFPTTEEAARASKAAGLGVLMGAPNVMRGASHSGNVSARTLAGDGLLDI 299 Query: 305 LSSDYIPSSLLMAALQLPRHVPAIDLASAVRTVTKTPAEAVGLNDRGEIAVGRRADLIRV 364 LSSDYIP SL+ +A L V I L AV V+K PAEAVGL DRG I GRRADL+RV Sbjct: 300 LSSDYIPFSLIQSAFFLGDMVEGISLPHAVAMVSKNPAEAVGLTDRGTIEQGRRADLVRV 359 Query: 365 HVARDLPVVRSVWREGGRVA 384 V +PVVR+VWR+G RVA Sbjct: 360 RVDDHVPVVRTVWRQGRRVA 379 >SMb21171 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism Sme Sinorhizobium meliloti Length = 379 Score = 349 bits (895), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 189/380 (49%), Positives = 247/380 (65%), Gaps = 3/380 (0%) Query: 5 QDTIIGNARLVLADRVIEQGWVAISGGKIAEFGEGRAPEAAEDAGGDLLMPGLIELHTDH 64 ++ ++ NAR+VL DR+++ G V I G+IA+ EG A A ED GD L+PGL+ELHTDH Sbjct: 3 KEQLLTNARIVLEDRILD-GSVLIRDGRIADISEG-ASAAGEDFEGDYLLPGLVELHTDH 60 Query: 65 LEMHYVPRPKVFWNPVAAVISYDGQLATSGITTVLDSLRVWREDGAEDVDGRAGVLAAAI 124 LE HY PRP V W +AA+ ++D Q+ TSGITTV D LR+ ++ + G +A A+ Sbjct: 61 LEAHYSPRPGVRWLKIAAIQAHDAQVVTSGITTVFDCLRLGSDEDSGFPKGEMRSMADAL 120 Query: 125 AAAREENLLRADHFLHLRCEVPMPDVVAEAKELIDRPDVRLMSLMDHTPGQRQFRDEVKL 184 A A++E LRADH +HLRCEV DV+ ++ + P VRL+SLMDH PGQRQF+ + Sbjct: 121 AQAKQEGRLRADHLIHLRCEVSTADVLEHYEDFRNDPQVRLVSLMDHAPGQRQFQTMDQY 180 Query: 185 RDYYRGKGGGMTDAQLDVLFARRFAYQKEYAVANTRAIVALAHEYRIPLASHDDTTDENV 244 YY+ K G +TD R+ A YA + A+ E I +ASHDD T E+V Sbjct: 181 TLYYKTKRG-LTDDAFAAFIERQQALSARYATPHRNALAKACAERGITVASHDDATVEHV 239 Query: 245 VDAVNDRVAVAEFPTTMEAARGLHAAGIDILMGAPNVVRGGSHSGNIAAVDLANEGMLDI 304 +++ + +AEFPT+ EAA H AG+ +LMGAPN+VRG SHSGNIAA DLA G+LD+ Sbjct: 240 EESIGYGIRLAEFPTSFEAAEASHRAGLSVLMGAPNIVRGKSHSGNIAARDLAKRGVLDV 299 Query: 305 LSSDYIPSSLLMAALQLPRHVPAIDLASAVRTVTKTPAEAVGLNDRGEIAVGRRADLIRV 364 LSSDY+P SL+ A L V +I L A+ VT TPA VGL DRG IAVG RAD+ RV Sbjct: 300 LSSDYVPFSLIHAPFILADEVESIGLPEAIAMVTATPARTVGLEDRGRIAVGLRADIARV 359 Query: 365 HVARDLPVVRSVWREGGRVA 384 +PVVR+VWREG RVA Sbjct: 360 RRPEGIPVVRTVWREGRRVA 379 >BMEI1106 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism Bme Brucella melitensis Length = 379 Score = 348 bits (892), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 184/379 (48%), Positives = 246/379 (64%), Gaps = 3/379 (0%) Query: 5 QDTIIGNARLVLADRVIEQGWVAISGGKIAEFGEGRAPEAAEDAGGDLLMPGLIELHTDH 64 +T++ NAR+VL D VI G V ++ G IA+ G A +D GD L PGL+ELHTDH Sbjct: 3 NETVLRNARIVLTDDVI-LGSVKLTDGLIADISAG-ASSVGDDMEGDFLTPGLVELHTDH 60 Query: 65 LEMHYVPRPKVFWNPVAAVISYDGQLATSGITTVLDSLRVWREDGAEDVDGRAGVLAAAI 124 LE HY PRP+V WNP+AAV ++D Q+A SGIT V D+LR+ + AE L+ AI Sbjct: 61 LEGHYAPRPRVRWNPIAAVQAHDAQIAASGITAVFDALRIGFDGEAETDIEDMRKLSNAI 120 Query: 125 AAAREENLLRADHFLHLRCEVPMPDVVAEAKELIDRPDVRLMSLMDHTPGQRQFRDEVKL 184 A R+ LRADHFLHLRCEV PD ++ + P V+L+SLMDH PGQRQF D Sbjct: 121 AEGRDAGRLRADHFLHLRCEVSAPDCLSAFERFGSHPLVKLVSLMDHAPGQRQFADIESY 180 Query: 185 RDYYRGKGGGMTDAQLDVLFARRFAYQKEYAVANTRAIVALAHEYRIPLASHDDTTDENV 244 + Y+ K ++ + + +R + Y+ + I L H I LASHDD T E+V Sbjct: 181 KAYFLRKSN-FSEEEFRLYCEKRIGQSQRYSAPTRKVIADLCHARGIILASHDDATVEHV 239 Query: 245 VDAVNDRVAVAEFPTTMEAARGLHAAGIDILMGAPNVVRGGSHSGNIAAVDLANEGMLDI 304 +A ++VAEFPTT AA+ A+G+ +LMGAPN+VRGGSHSGN++A +LA G LDI Sbjct: 240 AEAQAQGISVAEFPTTHMAAKASRASGMSVLMGAPNIVRGGSHSGNVSARELAEAGHLDI 299 Query: 305 LSSDYIPSSLLMAALQLPRHVPAIDLASAVRTVTKTPAEAVGLNDRGEIAVGRRADLIRV 364 +SSDYIP+S++ +A L V I L A+R V+ PA A+ L+DRGEIA G+RADL+RV Sbjct: 300 VSSDYIPASMMQSAFFLAEVVENISLPQAIRLVSANPARALRLDDRGEIAAGKRADLVRV 359 Query: 365 HVARDLPVVRSVWREGGRV 383 +A +P++R+VWREG RV Sbjct: 360 QMAGHVPIIRTVWREGQRV 378 >PA3374 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism Pae Pseudomonas aeruginosa Length = 387 Score = 299 bits (766), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 186/388 (47%), Positives = 245/388 (63%), Gaps = 9/388 (2%) Query: 3 VKQDTIIGNARLVLADRVIEQGWVAISGGKIAEFGEGRAPEA-AEDAGGDLLMPGLIELH 61 + + ++ NAR+V A+RV G V + G IA EGR+ A AED GGD L+PGL+ELH Sbjct: 1 MSSERVLSNARVVSAERVF-VGSVLLRDGLIAAVDEGRSHLAGAEDLGGDYLLPGLVELH 59 Query: 62 TDHLEMHYVPRPKVFWNPVAAVISYDGQLATSGITTVLDSLRVWREDGAEDVDGRAGVLA 121 TD+LE H PRP V W +AV+++D Q+ ++GITTV D+L + + + + Sbjct: 60 TDNLEKHMTPRPGVDWPSASAVLAHDAQIVSAGITTVFDALSIGDVNPKGKRMQQLPKML 119 Query: 122 AAIAAAREENLLRADHFLHLRCEVPMPDVVAEAKELIDRPDVRLMSLMDHTPGQRQFRDE 181 AI A RADH LHLRCEV P + +EL++ P V+L+S+MDH PGQRQF Sbjct: 120 EAIGEAAASGDARADHRLHLRCEVSHPQTLEVFRELVEHPLVQLVSVMDHAPGQRQFARL 179 Query: 182 VKLRDYYRGKGGGMTDAQLDVLFARRFAYQKEYAVANTRAIVALAHEYRIPLASHDDTTD 241 K R+YY+GK ++DA++D + A + Y+ A AIV + + +ASHDD T Sbjct: 180 EKYREYYQGKYH-LSDAEMDAFIVEQVANSERYSDAARAAIVDVCQGRGLSVASHDDATL 238 Query: 242 ENVVDAVNDRVAVAEFPTTMEAARGLHAAGIDILMGAPNVVRGGSHSGNIAAVDLANEGM 301 +V ++ +A+AEFPTT+EAAR H G+ +LMGAPNVVRGGSHSGN+AA LA G+ Sbjct: 239 AHVRESAGYGMAIAEFPTTVEAARASHEHGLQVLMGAPNVVRGGSHSGNVAAAQLAGIGV 298 Query: 302 LDILSSDYIPSSLLMAALQLP---RHVPAI--DLASAVRTVTKTPAEAVGLNDRGEIAVG 356 LDILSSDY P+SLL AAL L AI DL AV V++TPA A GL DRGEI VG Sbjct: 299 LDILSSDYYPASLLHAALLLAGEHSEYDAIRYDLPRAVAMVSRTPALAAGLTDRGEIRVG 358 Query: 357 RRADLIRVH-VARDLPVVRSVWREGGRV 383 RADL++ + + PVVR VWR G RV Sbjct: 359 LRADLLQARALGNNQPVVRQVWRGGQRV 386