BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0082.0060.p (434 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 159 1e-38 BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superf... 138 2e-32 AF0367 [GEPR] COG0477 Permeases of the major facilitator superfa... 121 4e-27 AGl3235 [GEPR] COG0477 Permeases of the major facilitator superf... 115 2e-25 mll4118 [GEPR] COG0477 Permeases of the major facilitator superf... 107 4e-23 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 159 bits (403), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 124/437 (28%), Positives = 212/437 (48%), Gaps = 30/437 (6%) Query: 5 MRLPFFYGWIIVAVTFVTMAIGVNARTAFSLFYPPIISEFGWERGITAGAFSFGFVASAI 64 M+ YGWIIVAVTF+T R +F F P +EF +RG + + F+ I Sbjct: 1 MKRKIHYGWIIVAVTFLTFLAVQGVRLSFGAFVQPWETEFSMDRGSISLISTLSFIVYGI 60 Query: 65 ASPLIGRLMDRGGPRAVMELGVLLMGSGLLLAPLTTQPWHLYLTIGVLVGAGSVCLGYSG 124 + PLIG+L+DR G R ++ LL+G +L + TQPWHL++ GV+V G Sbjct: 61 SQPLIGKLVDRLGARFILSCSTLLVGVSFVLTTMATQPWHLFILYGVVVSIGVGGASNVA 120 Query: 125 QSLFVPNWFVRRRGLAIGLAFAGVGIGSVTLLPWVQHMIEHTGWRTACTAMGIVVLVVLA 184 ++ + NWF ++RGLA G+ AG G G + L+P +I+ W+ +G + V++ Sbjct: 121 ATVVITNWFNKKRGLAFGIIEAGFGAGQMILVPGSLMLIQWLDWKATVVILGFFLAVIVF 180 Query: 185 PIN-LLLHKRPEDIGLQPDG---DAAPTATSARPASNIVDPVWAGTDWTLPRALRTARFW 240 PI LLL P + ++P G + T TS A+ ++W++ R FW Sbjct: 181 PIVLLLLRNHPSEKQVEPIGGVREEEETNTSPNSAT--------FSNWSV---FRMRPFW 229 Query: 241 WIAIGY-FCGLYIWYAVQVHQTKFLLDIGFSSSVSVWALGVVSLLGIPGQIWLGHLSDRI 299 ++ + + CG + H D GFS+SV+ A+ +++ I G + G ++DR Sbjct: 230 FLVLPFAICGFTTTGLMDTHLIPLSHDHGFSTSVTSAAVSLLAGFNIVGILLSGVIADR- 288 Query: 300 GREWVWAISCFGFVICFAALAAL-----KYWPNMALIYLMVFTQGALGYGLTSVMGPVVL 354 W+ F F++ A +L + P + L + ++F G + + + + Sbjct: 289 -----WSSRKFLFLLYVARALSLVILVHSHDPLLLLGFAILF--GLVDFATVAPTQLLAT 341 Query: 355 EIFQGKHYGSIFGTVMLAALAGGAAGPWITGQLYDLSGSYTSAFLLGIAVSLLSAVA-IW 413 + F+ G + G + L+ G A G ++ G LY+ +GSYT + + I + +++A+ ++ Sbjct: 342 QYFKRYSIGLMIGWLFLSHQVGSALGAYVPGLLYEQTGSYTVSLYVSIVILIVAAICNLF 401 Query: 414 QASPRKVRAVAGQMHKV 430 P K R Q V Sbjct: 402 LPEPNKQRNDVKQAEAV 418 >BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 416 Score = 138 bits (348), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 115/404 (28%), Positives = 192/404 (47%), Gaps = 18/404 (4%) Query: 11 YGWIIVAVTFVTMAIGVNARTAFSLFYPPIISEFGWERGITAGAFSFGFVASAIASPLIG 70 Y WIIV+VTF+ + R +F F P +F +R + + F+ I+ P+IG Sbjct: 6 YAWIIVSVTFLILLAVQGVRLSFGAFVEPWERQFSIDRSTISLISTVSFIVYGISQPVIG 65 Query: 71 RLMDRGGPRAVMELGVLLMGSGLLLAPLTTQPWHLYLTIGVLVGAGSVCLGYSGQSLFVP 130 RL+D+ G RAV+ LL G + L L T PW L+L G+ V G S+ V Sbjct: 66 RLVDKWGARAVLAWSALLTGVSIFLTYLVTSPWQLFLLYGLGVSLGVGGASNVAASVLVV 125 Query: 131 NWFVRRRGLAIGLAFAGVGIGSVTLLPWVQHMIEHTGWRTACTAMGIVVLVVLAPINLL- 189 NWF ++RGLA G+ AG G G + L+P +I W+ +G++++V++ P LL Sbjct: 126 NWFSKKRGLAFGIMEAGFGAGQMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVFPAALLM 185 Query: 190 LHKRPEDIGLQPDGDAAPTATSARPASNIVDPVWAGTDWTLPRALRTARFWWIAIGYF-C 248 L P + +P G A + P + T ++ R +FW++ + C Sbjct: 186 LRNNPSEKNTEPIGGLAASEKETAPKT---------TALSVAGMFRMRQFWFLIFPFLIC 236 Query: 249 GLYIWYAVQVHQTKFLLDIGFSSSVSVWALGVVSLLGIPGQIWLGHLSDRIGREWVWAIS 308 G + H F D GFS++V+ A+ +++ I G + G ++DR I Sbjct: 237 GFTTVGLMDTHLIPFSHDHGFSTTVTSAAVSLLAGFNIAGILLSGIVADRWSSR---KIL 293 Query: 309 CFGFVICFAALAALKY--WPNMALIYLMVFTQGALGYGLTSVMGPVVLEIFQGKHYGSIF 366 C + + ++ L Y P + L + ++F G + + + + + FQ G + Sbjct: 294 CILYAVRALSIVILIYSHEPYLLLAFAILF--GLVDFATVAPTQMLATQYFQNYSIGLMI 351 Query: 367 GTVMLAALAGGAAGPWITGQLYDLSGSYTSAFLLGIAVSLLSAV 410 G + LA G A G ++ G +Y ++G YT AF L I + +L++V Sbjct: 352 GWLSLAHQIGSALGAYVPGVIYTVTGEYTLAFYLSIGMLVLASV 395 >AF0367 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 397 Score = 121 bits (303), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 109/386 (28%), Positives = 177/386 (45%), Gaps = 28/386 (7%) Query: 32 AFSLFYPPIISEFGWERGITAGAFSFGFVASAIASPLIGRLMDRGGPRAVMELGVLLMGS 91 A+S+F P+++ FGW + I + FS + A+ GR DR GPR V LG +L+G Sbjct: 23 AWSVFVNPLMNTFGWSKTIASLPFSIFLLIFALMMVPAGRTQDRIGPRKVAMLGGVLLGV 82 Query: 92 GLLLAPLTT---QPWHLYLTIGVLVGAGSVC-LGYSGQSLFVPNWFVRRRGLAIGLAFAG 147 G LL+ L P+ L + GV+ GAG C LGY+ WF R GLA GL G Sbjct: 83 GFLLSGLIESIQSPYWLIFSYGVIAGAG--CGLGYACPIPVARKWFPERVGLATGLVVMG 140 Query: 148 VGIGSVTLLPWVQHMIEHTGWRTACTAMGIVVLVVLAPINLLLHKRPEDIGLQPDGDAAP 207 G+ ++ P + +I+ G T +G+++L+V LL PE +Q A Sbjct: 141 FGMSALIFAPLERILIDTYGISTTFYILGVILLIVAVFAASLLSNPPELPAVQASNPAKV 200 Query: 208 TATSARPASNIVDPVWAGTDWTLPRALRTARFWWIAIGYFCGLYIWYAVQVHQTKFLLDI 267 + +P + LR RF+ + + +F V H + + Sbjct: 201 EVVTGKP------------ELGPSEMLRDYRFYVLWLSFFFMALAGLMVIGHIAPYAQER 248 Query: 268 GFSSSVSVWALGVVSLLGIPGQIWLGHLSDRIGREWVWAISCFGFVICFAALAALKYWPN 327 G + +A+ ++S+ G+ G LSD+IGR FV+ L +P+ Sbjct: 249 GLEPLAAAFAVSILSVANAVGRPGAGALSDKIGRAMTM------FVLFLIQGITLIAFPH 302 Query: 328 MALIYLMVFTQGAL---GYGLTSVMGPVVL-EIFQGKHYGSIFGTVMLAALAGGAAGPWI 383 +AL + ++ A+ YG + P + F K+ G +G V + GG GP + Sbjct: 303 VALTLITIYICAAIIGFNYGANFSLFPSATGDFFGTKNLGVNYGLVFTSYGVGGLVGPIM 362 Query: 384 TGQLYDLSGSYTSAFLLGIAVSLLSA 409 G ++D++GSY AFL+ ++L++A Sbjct: 363 AGYVFDVTGSYEIAFLVAGVLALIAA 388 >AGl3235 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 433 Score = 115 bits (289), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 82/296 (27%), Positives = 129/296 (43%), Gaps = 5/296 (1%) Query: 11 YGWIIVAVTFVTMAIGVNARTAFSLFYPPIISEFGWERGITAGAFSFGFVASAIASPLIG 70 YGW++ TF+TM A + + P+ EFGW+ + A + V + P Sbjct: 19 YGWVVAVTTFLTMLATAGAMGSAGVMIQPLHQEFGWDIADISSAMAVRLVLFGLLGPFAA 78 Query: 71 RLMDRGGPRAVMELGVLLMGSGLLLAPLTTQPWHLYLTIGVLVGAGSVCLGYSGQSLFVP 130 M+ G R V+ + L+ G++ + TQ W L L GV++G G+ + Sbjct: 79 AFMNHFGIRQVVSTALALIMGGIVASFFMTQVWQLLLLWGVVIGVGTGMTALVLGATVAS 138 Query: 131 NWFVRRRGLAIGLAFAGVGIGSVTLLPWVQHMIEHTGWRTACTAMGIVVLVVLAPINLLL 190 WF +RRGL IGL A G + LP + + E GWRTA T V+ + + LL+ Sbjct: 139 RWFSKRRGLVIGLMTASNATGQLVFLPLLAALTEAYGWRTALTLSVAVIAAAMILVLLLM 198 Query: 191 HKRPEDIGLQPDGDAAPTATSARPASNIVDPVWAGTDWTLPRALRTARFWWIAIGYF--C 248 P D+GL G+ TA S P + + +++ +W+ G F C Sbjct: 199 RDHPSDVGLPAYGE---TAVSKPPKQDHNLLATLASPLVTLKSVSGNPVFWVLFGTFFVC 255 Query: 249 GLYIWYAVQVHQTKFLLDIGFSSSVSVWALGVVSLLGIPGQIWLGHLSDRIGREWV 304 GL +Q H D G ++ + L V+ + G I+ G LSDR ++ Sbjct: 256 GLSTNGLIQTHWISICGDFGMAAVTAAGTLAVIGIFDFFGTIFAGWLSDRFDNRFL 311 >mll4118 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 446 Score = 107 bits (268), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 90/292 (30%), Positives = 136/292 (46%), Gaps = 9/292 (3%) Query: 11 YGWIIVAVTFVTMAIGVNARTAFSLFYPPIISEFGWERGITAGAFSFGFVASAIASPLIG 70 Y +++V V F+ + I R+A ++ P+ + FGW R + + A G + + P Sbjct: 31 YAFVVVGVIFLCLLIAAGLRSAPAVMMLPLENSFGWRRDVISLAAGVGILLYGLTGPFAA 90 Query: 71 RLMDRGGPRAVMELGVLLMGSGLLLAPLTTQPWHLYLTIGVLVGAGSVCLGYSGQSLFVP 130 LM+R G R + +L+M L+ L T+PWHL++T GV G GS + + V Sbjct: 91 ALMERIGLRRTLIASLLVMSGSTALSLLMTKPWHLFITWGVFSGIGSGAVASVLGATIVN 150 Query: 131 NWFVRRRGLAIGLAFAGVGIGSVTLLPWVQHMIEHTGWRTACTAMGIVVLVVLAPINLLL 190 WF RGL +GL A G + LP + + + GW+ A+ + +L + LL+ Sbjct: 151 RWFKTNRGLVMGLMSASSATGLLVFLPLLASLAQSGGWKPVAVAVAVATACLLPLVWLLV 210 Query: 191 HKRPEDIGLQPDGDAAPTATSARPASNIVDPVWAGTDWTLPRALRTARFWWIAIGYF-CG 249 +RP IG+ G A PAS A T TL RA T FW++ +F CG Sbjct: 211 PERPASIGMVRYGAEADDVPPVPPASQ--GNFLAHTLNTLRRAAGTRVFWYLFATFFVCG 268 Query: 250 LYIWYAVQVHQTKFLLDIGFSSSVSVWALGVVSLLGI---PGQIWLGHLSDR 298 V H F D+G V A G++S++GI G G L+DR Sbjct: 269 FTTNGLVGTHLIAFCGDMGIG---EVQAAGLLSMMGIFDLIGTTLSGWLTDR 317