BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0082.0014.p (403 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI1292 [GEPR] COG0477 Permeases of the major facilitator super... 412 e-115 YPO3093 [GEPR] COG0477 Permeases of the major facilitator superf... 398 e-110 mlr2687 [GEPR] COG0477 Permeases of the major facilitator superf... 397 e-110 Zfsr [GEPR] COG0477 Permeases of the major facilitator superfami... 397 e-110 ECs0532 [GEPR] COG0477 Permeases of the major facilitator superf... 397 e-110 >BMEI1292 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 403 Score = 412 bits (1059), Expect = e-115, Method: Compositional matrix adjust. Identities = 209/383 (54%), Positives = 278/383 (72%), Gaps = 15/383 (3%) Query: 30 VVLAGISFSHFLNDTMQSLIASVYPILKDNYALDFAQIGMITLAFQFTASLLQPLVGHFT 89 ++ S HFLND MQSL+ ++YP+LK+NY+L F QIG++T FQ TAS+LQPLVG +T Sbjct: 20 TIILATSLGHFLNDMMQSLLPAIYPMLKENYSLSFWQIGLLTFTFQMTASILQPLVGIYT 79 Query: 90 DKKAQPFSLAIGMGFTFFGLLLLSVAHTYGVILIAASLVGLGSAVFHPESSRIARLASGG 149 D+K P+SL GMG T GL+ L+ AH Y +L+ A+ VG GS+VFHPE++R+ARLASGG Sbjct: 80 DRKPMPYSLTFGMGCTLIGLVFLATAHHYSFLLLGAACVGFGSSVFHPEAARVARLASGG 139 Query: 150 RYGFAQSVFQLGGSFGTSMGPVLAALIVVPXS---------IAFLAIVILWRIGVWYKPQ 200 R+GFAQS+FQ+GG+FG+S+GP+LAA IV+P A + + +LW +G WY Sbjct: 140 RHGFAQSLFQVGGNFGSSIGPLLAAFIVLPFGQISVSWFSVAALIGMFVLWYVGNWYNRY 199 Query: 201 ISGRKAAASARHPDHP---DQRRVRIALIVLVALLFSKQLYVSSLSSYYIFYLIDRFGVS 257 R A A+ PD + RV ++ VL L+F+K +Y++SL+SYY FY I FGVS Sbjct: 200 ---RLANANKPKPDKTLPLPRNRVIASVAVLALLVFTKYIYMASLTSYYTFYTISHFGVS 256 Query: 258 TQAAQLYLFVFLAANAAGAFIGGPLGDRFGRKYVIWFSILGALPFTLALPYAGLFASAVL 317 Q +QL LF+FL A AAG IGGP+GD+ G + VIW SILG LPFTLALPYA L +AVL Sbjct: 257 VQTSQLLLFLFLGAVAAGTIIGGPIGDKIGARKVIWASILGVLPFTLALPYANLEMTAVL 316 Query: 318 TVVIGLIISSATSAIIVFAQELMPHRFGMISGVFFGVAFGIGGLGAAVLGKLADHTSIAF 377 T++IGLI++SA AIIVFAQEL+P R GM+SG+FFG AFG+ G+ AAVLG +AD I F Sbjct: 317 TIIIGLILASAFPAIIVFAQELLPGRVGMLSGLFFGFAFGMAGIAAAVLGIVADQKGIEF 376 Query: 378 VYQLCAFLPAIGLLAVFLPKMPK 400 VY++C++LP +GLL +FLPK+ + Sbjct: 377 VYRICSYLPFLGLLTIFLPKLER 399 >YPO3093 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 404 Score = 398 bits (1022), Expect = e-110, Method: Compositional matrix adjust. Identities = 221/389 (56%), Positives = 291/389 (74%), Gaps = 12/389 (3%) Query: 21 KAAVAGPAYVVLAGISFSHFLNDTMQSLIASVYPILKDNYALDFAQIGMITLAFQFTASL 80 +V ++ +L IS SH LND +QSLI ++YP+L+ ++L FAQIG+ITL +Q TASL Sbjct: 14 NVSVKRTSFSILGAISVSHLLNDMIQSLILAIYPLLQAEFSLSFAQIGLITLTYQLTASL 73 Query: 81 LQPLVGHFTDKKAQPFSLAIGMGFTFFGLLLLSVAHTYGVILIAASLVGLGSAVFHPESS 140 LQPL+G +TDK QP+SL IGMGFT G+LLL+VA T+ V+L+AA+LVG GS+VFHPESS Sbjct: 74 LQPLIGLYTDKHPQPYSLPIGMGFTLSGILLLAVATTFPVVLLAAALVGTGSSVFHPESS 133 Query: 141 RIARLASGGRYGFAQSVFQLGGSFGTSMGPVLAALIVVPXS---------IAFLAIVILW 191 R+AR+ASGGR+G AQSVFQ+GG+FG+++GP+LAA+I+ P A LAIV+L Sbjct: 134 RVARMASGGRHGLAQSVFQVGGNFGSALGPLLAAIIIAPYGKGNVGWFSLAALLAIVVLL 193 Query: 192 RIGVWYKPQ--ISGRKAAASARHPDHPDQRRVRIALIVLVALLFSKQLYVSSLSSYYIFY 249 ++ WYK Q S K + P + + L +L+ L+FSK Y++S+SSYY FY Sbjct: 194 QVSKWYKLQQRASYGKVLKISSAKTLPKNKIIS-TLAILMVLIFSKYFYLTSISSYYTFY 252 Query: 250 LIDRFGVSTQAAQLYLFVFLAANAAGAFIGGPLGDRFGRKYVIWFSILGALPFTLALPYA 309 LI +FGVS Q+AQ++LFVFL A AAG IGGPLGD+ GRKYVIW SILG PFTLALPYA Sbjct: 253 LIHKFGVSVQSAQIHLFVFLFAVAAGTIIGGPLGDKIGRKYVIWGSILGVAPFTLALPYA 312 Query: 310 GLFASAVLTVVIGLIISSATSAIIVFAQELMPHRFGMISGVFFGVAFGIGGLGAAVLGKL 369 L+ + +LTV IG+I++SA SAI+V+AQEL+P + GM+SG+FFG AFG+GG+GAAVLG + Sbjct: 313 SLYWTGILTVFIGVILASAFSAILVYAQELIPGKVGMVSGLFFGFAFGMGGIGAAVLGYV 372 Query: 370 ADHTSIAFVYQLCAFLPAIGLLAVFLPKM 398 AD TSI VYQ+CAFLP +G+ LP + Sbjct: 373 ADLTSIELVYQICAFLPLLGIFTALLPNL 401 >mlr2687 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 423 Score = 397 bits (1021), Expect = e-110, Method: Compositional matrix adjust. Identities = 223/397 (56%), Positives = 292/397 (73%), Gaps = 13/397 (3%) Query: 18 TAAKAAVAGPAYVVLAGISFSHFLNDTMQSLIASVYPILKDNYALDFAQIGMITLAFQFT 77 TA+ A+ A+ V+ +SF H +ND MQSL++++YP+LK NY LDF QIG++T FQ T Sbjct: 24 TASHASAQATAFTVILAVSFCHCINDIMQSLLSAIYPLLKQNYGLDFWQIGLLTFTFQVT 83 Query: 78 ASLLQPLVGHFTDKKAQPFSLAIGMGFTFFGLLLLSVAHTYGVILIAASLVGLGSAVFHP 137 ASLLQP++G TDK+ P+SL GM + GL++L+ A Y ++LI ASL+G+GSA+FHP Sbjct: 84 ASLLQPVIGMITDKRPMPYSLPYGMASSLIGLVVLAYAGHYYLLLIGASLIGIGSAIFHP 143 Query: 138 ESSRIARLASGGRYGFAQSVFQLGGSFGTSMGPVLAALIVVP---XSIAFLA------IV 188 ESSRIAR ASGGR+G AQS+FQ+GG+FG SMGP+LAA IVVP SIA+ A IV Sbjct: 144 ESSRIARFASGGRFGLAQSLFQVGGNFGQSMGPLLAAFIVVPFGQTSIAWFAVGSLIGIV 203 Query: 189 ILWRIGVWYKP--QISGRKAAASARHPDHPDQRRVRIALIVLVALLFSKQLYVSSLSSYY 246 +LW++G WY G + A S P +R+V ALIVL L+ SK Y++SL+SYY Sbjct: 204 VLWQVGGWYSRLRAAQGTRKAVSFVSPF--PRRKVMSALIVLTLLVLSKNAYIASLASYY 261 Query: 247 IFYLIDRFGVSTQAAQLYLFVFLAANAAGAFIGGPLGDRFGRKYVIWFSILGALPFTLAL 306 FY I +FGVS Q +Q+ LF+FL A+A G +GGP GDR+G+K +IWFSI+G LPFTLAL Sbjct: 262 TFYSIHKFGVSVQMSQVMLFLFLGASALGILLGGPFGDRYGQKAMIWFSIVGVLPFTLAL 321 Query: 307 PYAGLFASAVLTVVIGLIISSATSAIIVFAQELMPHRFGMISGVFFGVAFGIGGLGAAVL 366 PYA L + VLTV+IGLI+SSA S I+VFAQEL+P R GMI+G+FFG AFG+GG+ AAVL Sbjct: 322 PYANLEWTMVLTVLIGLILSSAFSNIVVFAQELVPGRVGMIAGIFFGFAFGMGGIAAAVL 381 Query: 367 GKLADHTSIAFVYQLCAFLPAIGLLAVFLPKMPKAVR 403 G +AD I FV+Q+C++LP +GLL VFLP M +A + Sbjct: 382 GVVADMKGIDFVFQVCSYLPLLGLLTVFLPNMKEARK 418 >Zfsr [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 406 Score = 397 bits (1019), Expect = e-110, Method: Compositional matrix adjust. Identities = 219/388 (56%), Positives = 289/388 (74%), Gaps = 9/388 (2%) Query: 19 AAKAAVAGPAYVVLAGISFSHFLNDTMQSLIASVYPILKDNYALDFAQIGMITLAFQFTA 78 AA A ++ +L IS SH LND +QSLI ++YP+L+ ++L F QIGMITL FQ + Sbjct: 14 AASTTKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQSEFSLTFMQIGMITLTFQLAS 73 Query: 79 SLLQPLVGHFTDKKAQPFSLAIGMGFTFFGLLLLSVAHTYGVILIAASLVGLGSAVFHPE 138 SLLQP+VG++TDK P+SL IGM FT GL+LL++A ++G +L+AA+LVG GS+VFHPE Sbjct: 74 SLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSFGAVLLAAALVGTGSSVFHPE 133 Query: 139 SSRIARLASGGRYGFAQSVFQLGGSFGTSMGPVLAALIVVPXS---------IAFLAIVI 189 SSR+AR+ASGGR+G AQS+FQ+GG+FG+S+GP+LAA+I+ P A LAIV+ Sbjct: 134 SSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVV 193 Query: 190 LWRIGVWYKPQISGRKAAASARHPDHPDQRRVRIALIVLVALLFSKQLYVSSLSSYYIFY 249 L +I WY Q K A + + +V +A+ +L+ L+FSK Y++S+SSYY FY Sbjct: 194 LAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILLILIFSKYFYMASISSYYTFY 253 Query: 250 LIDRFGVSTQAAQLYLFVFLAANAAGAFIGGPLGDRFGRKYVIWFSILGALPFTLALPYA 309 L+ +FG+S Q AQL+LF FL A AAG IGGP+GD+ GRKYVIW SILG PFTL LPYA Sbjct: 254 LMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYA 313 Query: 310 GLFASAVLTVVIGLIISSATSAIIVFAQELMPHRFGMISGVFFGVAFGIGGLGAAVLGKL 369 L + VLTV+IG I++SA SAI+V+AQEL+P R GM+SG+FFG AFG+GGLGAAVLG + Sbjct: 314 SLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLI 373 Query: 370 ADHTSIAFVYQLCAFLPAIGLLAVFLPK 397 ADHTSI VY++CAFLP +G+L +FLP Sbjct: 374 ADHTSIELVYKICAFLPLLGMLTIFLPD 401 >ECs0532 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 406 Score = 397 bits (1019), Expect = e-110, Method: Compositional matrix adjust. Identities = 219/388 (56%), Positives = 289/388 (74%), Gaps = 9/388 (2%) Query: 19 AAKAAVAGPAYVVLAGISFSHFLNDTMQSLIASVYPILKDNYALDFAQIGMITLAFQFTA 78 AA A ++ +L IS SH LND +QSLI ++YP+L+ ++L F QIGMITL FQ + Sbjct: 14 AASTTKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQSEFSLTFMQIGMITLTFQLAS 73 Query: 79 SLLQPLVGHFTDKKAQPFSLAIGMGFTFFGLLLLSVAHTYGVILIAASLVGLGSAVFHPE 138 SLLQP+VG++TDK P+SL IGM FT GL+LL++A ++G +L+AA+LVG GS+VFHPE Sbjct: 74 SLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSFGAVLLAAALVGTGSSVFHPE 133 Query: 139 SSRIARLASGGRYGFAQSVFQLGGSFGTSMGPVLAALIVVPXS---------IAFLAIVI 189 SSR+AR+ASGGR+G AQS+FQ+GG+FG+S+GP+LAA+I+ P A LAIV+ Sbjct: 134 SSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVV 193 Query: 190 LWRIGVWYKPQISGRKAAASARHPDHPDQRRVRIALIVLVALLFSKQLYVSSLSSYYIFY 249 L +I WY Q K A + + +V +A+ +L+ L+FSK Y++S+SSYY FY Sbjct: 194 LAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILLILIFSKYFYMASISSYYTFY 253 Query: 250 LIDRFGVSTQAAQLYLFVFLAANAAGAFIGGPLGDRFGRKYVIWFSILGALPFTLALPYA 309 L+ +FG+S Q AQL+LF FL A AAG IGGP+GD+ GRKYVIW SILG PFTL LPYA Sbjct: 254 LMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYA 313 Query: 310 GLFASAVLTVVIGLIISSATSAIIVFAQELMPHRFGMISGVFFGVAFGIGGLGAAVLGKL 369 L + VLTV+IG I++SA SAI+V+AQEL+P R GM+SG+FFG AFG+GGLGAAVLG + Sbjct: 314 SLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLI 373 Query: 370 ADHTSIAFVYQLCAFLPAIGLLAVFLPK 397 ADHTSI VY++CAFLP +G+L +FLP Sbjct: 374 ADHTSIELVYKICAFLPLLGMLTIFLPD 401