BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0077.0004.p         (748 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA0165 [S] COG1944 Uncharacterized conserved protein Mac Methano...   108   6e-23
MTH987 [S] COG1944 Uncharacterized conserved protein Mth Methano...    97   2e-19
MJ1094 [S] COG1944 Uncharacterized conserved protein Mja Methano...    85   6e-16
mlr7074 Non COG                                                        67   1e-10
MK0115 [S] COG1944 Uncharacterized conserved protein Mka Methano...    66   4e-10

>MA0165 [S] COG1944 Uncharacterized conserved protein Mac Methanosarcina
           acetivorans str.C2A
          Length = 424

 Score =  108 bits (269), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 89/333 (26%), Positives = 156/333 (46%), Gaps = 22/333 (6%)

Query: 392 GKGSTAEQGEASALMEAIERYSGIFQGDEIRTKRRFVDFAPGDALLPNEVQLFSDAQFQN 451
           GKGST ++   SA+ME+ ER      G     +        G    P  V+ +S+AQ +N
Sbjct: 72  GKGSTEQRARISAIMESFERCLAERPGVNANIE--------GGISAPALVESYSNAQ-EN 122

Query: 452 RHTSQPDDSHLVPEPLDPSTKTEWSPVWSLRDKRFKHLPTGLLYFFYGG-------FHTD 504
            +   P+ S L+ +P +P +  EW   + L ++    +    +Y  Y         F ++
Sbjct: 123 CNVLDPN-SLLLSQPFNPGSLLEWVGAYDLMNREEVFVNANAVYHPYDAPGQCQKLFLSN 181

Query: 505 SNGCAAGNTREEAIVQGFLELVERDAYAIWWYNRLQRAEVDLAQFEDPYVRDLQAQLADA 564
           +NG A+GN  EEAI+ G LE++ERDA +   + R    E+ L + ED Y+ +L  +  D 
Sbjct: 182 TNGLASGNVLEEAILHGLLEVIERDAISTAQFTRNLGKEIVLTE-EDGYLYELARKFKDT 240

Query: 565 GRRLWVLDITSDLGIPSYVAIIHWTQ-NGHENIEFGSGSHFDRRIALLRSLTELTQFMSI 623
           G  L +  + +D GIP+ +A     +      +  G+GSH    IA+ R++TE  Q   +
Sbjct: 241 GIDLKIWLVPTDTGIPTIIAATDDVKLKDPALLVMGAGSHLKPEIAIARAITEAAQSRVV 300

Query: 624 GMMGG--GSGEKPTLDGVTPLRLDDYPFLIPSENPIVPSAPSLKVHDNA-RDQVNACIEI 680
            + G    +  +  +  V   R+    +    E   +  +    +   +  + ++  +E 
Sbjct: 301 QIQGAREDTDREGFIRSVGYDRMKRLNWFWFEEGEKISLSEVKDLSGKSPTENIDIILEQ 360

Query: 681 ATGAGFDFLVLDQTRPDVQVPVVRVLVPGLRHF 713
             G     +V+D +R ++ VPVVRV++PG   F
Sbjct: 361 LKGLTEKVIVVDLSREEIAVPVVRVIIPGFELF 393


>MTH987 [S] COG1944 Uncharacterized conserved protein Mth
           Methanothermobacter thermautotrophicus
          Length = 383

 Score = 96.7 bits (239), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 71/245 (28%), Positives = 116/245 (47%), Gaps = 33/245 (13%)

Query: 392 GKGSTAEQGEASALMEAIERYSGIFQGDEIRTKRRFVD---FAPGDALLPNEVQLFSDAQ 448
           GKG+T  Q  ASA+MEA ERYS   + ++        D     P   +LP    L S+ +
Sbjct: 58  GKGATRTQARASAMMEAFERYSAERKPEDETFTAHPEDCDGLDPESLILPGSTDLKSELE 117

Query: 449 FQNRHTSQPDDSHLVP-----EPLDPSTKTEWSPVWSLRDKRFKHLPTGLLYFFYGGFHT 503
           + N      D+   VP      P +P                    P G +      F +
Sbjct: 118 WINAENLTGDEEVPVPANAVFHPYNP--------------------PEGCMSL----FRS 153

Query: 504 DSNGCAAGNTREEAIVQGFLELVERDAYAIWWYNRLQRAEVDLAQFEDPYVRDLQAQLAD 563
           ++NG A+GN REEAI  G +E++ERDA++++   R  + EVD +  ++  +  L  +   
Sbjct: 154 NTNGLASGNAREEAIFHGLMEVIERDAWSLFEARRGPKVEVDCSGTDNDIISGLLEKFHA 213

Query: 564 AGRRLWVLDITSDLGIPSYVAIIHWT-QNGHENIEFGSGSHFDRRIALLRSLTELTQFMS 622
           AG  + ++D+T+D G+ +  A+   T       +  G G+H D  IA++R+LTE+ Q  +
Sbjct: 214 AGVEVTLVDLTADTGVATVAAVADDTVLRDPALLTMGVGTHLDPEIAVIRALTEVAQSRA 273

Query: 623 IGMMG 627
             + G
Sbjct: 274 TQIHG 278


>MJ1094 [S] COG1944 Uncharacterized conserved protein Mja Methanococcus
           jannaschii
          Length = 385

 Score = 85.1 bits (209), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 61/239 (25%), Positives = 113/239 (47%), Gaps = 30/239 (12%)

Query: 391 FGKGSTAEQGEASALMEAIERYSGIFQGDEIRTKRRFVDFAPGDALLPNEVQLFSDAQFQ 450
           +GKG+   Q + SA MEAIER+S  +  ++++ K       P + +   ++         
Sbjct: 66  YGKGANDIQAKVSACMEAIERFSASYDKNKVKEK-------PDNPINVEDL--------- 109

Query: 451 NRHTSQPDDSHLVPEPLDPSTKTEWSPVWSLRDKRFKHLPTGLLYFFYGG--FHTDSNGC 508
                      ++P+  D + K EW     + +     +P   +++   G  F  ++NG 
Sbjct: 110 -----------ILPQYADKNVK-EWVEGIDIINNETIDVPADAVFYPTSGKLFRGNTNGL 157

Query: 509 AAGNTREEAIVQGFLELVERDAYAIWWYNRLQRAEVDLAQFEDPYVRDLQAQLADAGRRL 568
           A+GN  +EAI+   LE++ERDA+++    R    +++    ++P + +L  +   AG ++
Sbjct: 158 ASGNNLDEAILHATLEIIERDAWSLADLARKIPTKINPEDAKNPLIHELIEKYEKAGVKI 217

Query: 569 WVLDITSDLGIPSYVAIIHWTQNGHENIEFGSGSHFDRRIALLRSLTELTQFMSIGMMG 627
            + D+TS+  IP   AI          +  G G H    IA+LR+LTE+ Q  +  + G
Sbjct: 218 ILKDLTSEFEIPVVAAISDDLSKNPLMLCVGVGCHLHPEIAILRALTEVAQSRASQLHG 276


>mlr7074 Non COG
          Length = 410

 Score = 67.4 bits (163), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 72/258 (27%), Positives = 106/258 (41%), Gaps = 13/258 (5%)

Query: 475 WSPVWSLRDKRFKHLPTGLLYFFYG-GFHTDSNGCAAGNTREEAIVQGFLELVERDAYAI 533
           W PV  L D R  +LP  L            S GCAAG T E A+    LE +ERDA A 
Sbjct: 140 WVPVRRLDDGRQGYLPETLFIRSANRSAWVTSCGCAAGITHEAALTSALLEAIERDAAAG 199

Query: 534 WWYNRLQRAEVDLAQFEDPYVRDLQAQL--ADAGRRLWVLDITSDLGIPSYVAIIHWTQN 591
           WW +R     + L       V DL A++     GR    LDI+ +   P  +A + +  +
Sbjct: 200 WWRSRRGGRLIGLEALAGAGVLDLLARIRQEKLGRCTQFLDISGEFPAP-VIAALSFDAD 258

Query: 592 GHENIEFGSGSHFDRRIALLRSLTELTQF---MSIGMMGGGSGEKPTLDGVTPLRLD--D 646
           G   +  G     D   AL  +L E+ Q    + +  M         LD V  L+ +  +
Sbjct: 259 GR-GLAVGLACRLDAGNALRAALLEMCQMELALDLAAMKRAEQGVERLDEVDRLQAERAE 317

Query: 647 YPFLIPSENPIVPSAPSLKVHDNARDQVN--ACIEIATGAGFDFLVLDQTRPDVQVPVVR 704
            P  I + + +   +  + +H N    +N  + +       +     D T P   +PV +
Sbjct: 318 TPGAIDT-DLVSHLSSGVLMHKNDEKDLNFVSLVGEMLKKQYRIYAADLTTPMFDIPVAK 376

Query: 705 VLVPGLRHFYRRFAPGRL 722
           V VPGL+ F   F   RL
Sbjct: 377 VFVPGLQPFPSPFQSRRL 394


>MK0115 [S] COG1944 Uncharacterized conserved protein Mka Methanopyrus
           kandleri AV19
          Length = 377

 Score = 65.9 bits (159), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 83/339 (24%), Positives = 138/339 (40%), Gaps = 61/339 (17%)

Query: 392 GKGSTAEQGEASALMEAIERYSGIFQGDEIRTKRRFVDFAP-GDALLPNEVQLFSDAQFQ 450
           GKG+T  Q   SA ME +ER +          +   ++  P GD   P        A ++
Sbjct: 63  GKGTTRIQARVSAAMECVERAAA-------EPREEIIERGPEGDKWTP--------AWYR 107

Query: 451 NRHTSQPDDSHLVPEPLDPSTKTEWSPVWSLRDKRFKHLPTGLLYFFYGG--FHTDSNGC 508
                         EP       EW     L  +   ++P   ++  + G    + +NG 
Sbjct: 108 T-------------EP------REWVEGVDLTTREPVYVPANEVFHPWLGDALPSHTNGL 148

Query: 509 AAGNTREEAIVQGFLELVERDAYAIWWYNRLQRAEVDLAQFEDPYVRDLQAQLADAGRRL 568
           +AG  REEA++QG LE+VERD+++I  Y R+   E+++    +   R L+ ++     RL
Sbjct: 149 SAGRLREEAVIQGLLEVVERDSWSIVEYFRIHPPELEVHGELEELRRSLEREVGRVELRL 208

Query: 569 WVLDITSDLGIPSYVAIIHWT-----QNGHENIEFGSGSHFDRRIALLRSLTELTQFMSI 623
                     +PS V  ++           E +  G G+  D  +A+LR+L E+ Q +S+
Sbjct: 209 ----------LPSRVEGVYVVGAVTEAERVEEMVMGFGASPDPEMAVLRALLEVAQGLSM 258

Query: 624 GMMG------GGSGEKPTLDGVTPLRLD--DYPFLIPSENPIVPSAPSLKVHDNARDQVN 675
              G       G GE      +TP RL   +  +  P     +     +    +      
Sbjct: 259 ARRGIESPVRKGLGEFSAPGKLTPERLKRLNRHWFEPEGTVEIDDLDRVITTGSLEKLTE 318

Query: 676 ACIEIATGAGFDFLV-LDQTRPDVQVPVVRVLVPGLRHF 713
             +E    AG   ++ +D T  ++ VPVVRV V G   +
Sbjct: 319 ELVERVAEAGLGKVIEVDLTLENLDVPVVRVRVTGASEY 357